Motif ID: NKX3-1.p2

Z-value: 1.189

Transcription factors associated with NKX3-1.p2:

NameEntrezDescription
Nkx3-1 18095 NK-3 transcription factor, locus 1 (Drosophila)



Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chrM_+_14143 8.936


chrM_+_3913 5.191


chrM_+_3844 4.278


chrM_+_3320 4.129


chr7_-_29678773 3.482 Actn4
actinin alpha 4
chrM_+_13998 2.978


chr12_+_110798661 2.929 Meg3
maternally expressed 3
chr1_-_180264067 2.433 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr1_-_88253690 2.312 Ncl
nucleolin
chrM_+_409 2.242


chrM_+_1091 2.183


chrM_+_2750 2.147


chrM_+_13543 2.140


chrM_+_13320 2.076


chr15_-_81222718 1.743 St13
suppression of tumorigenicity 13
chr1_+_19198994 1.676 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr4_+_45310018 1.619 NM_027266
Rg9mtd3
RNA (guanine-9-) methyltransferase domain containing 3
chr11_-_69182891 1.612 NM_146019
Chd3
chromodomain helicase DNA binding protein 3
chr2_+_155212676 1.557 Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr9_-_71743854 1.531 Tcf12
transcription factor 12
chrM_-_13886 1.515


chr15_-_56526052 1.398 NM_008216
Has2
hyaluronan synthase 2
chr2_+_91386476 1.365 NM_001165989
NM_029437
Ckap5

cytoskeleton associated protein 5

chr6_+_33922645 1.361


chr2_+_152495244 1.335 H13
histocompatibility 13
chr4_+_103291963 1.311


chr17_-_35971913 1.266 Tubb5
tubulin, beta 5
chrM_+_11741 1.266 ND5
NADH dehydrogenase subunit 5
chr1_-_42749940 1.260 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr9_+_104472090 1.250 NM_028719
Cpne4
copine IV
chr3_+_75878452 1.223 NM_178673
Fstl5
follistatin-like 5
chr2_+_37372112 1.207 NM_177383
Gpr21
G protein-coupled receptor 21
chrY_-_582062 1.159 NM_009484
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr8_-_55809700 1.158 NM_001172152
Wdr17
WD repeat domain 17
chr10_+_18189773 1.088 NM_001163592
Nhsl1
NHS-like 1
chrM_-_622 1.086


chr13_-_64376186 0.961 NM_172587
Cdc14b
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr6_+_5340417 0.956 Asb4
ankyrin repeat and SOCS box-containing 4
chr13_+_14722530 0.923 AW209491
expressed sequence AW209491
chr1_-_77511653 0.920 NM_007936
Epha4
Eph receptor A4
chr11_+_77499638 0.910 NM_001024205
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr2_-_24618566 0.885 NM_001042528
NM_007579
Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

chrM_+_11812 0.865


chr7_+_107789414 0.857 Rab6
RAB6, member RAS oncogene family
chr1_-_128634766 0.848 Nckap5
NCK-associated protein 5
chr7_+_107685608 0.807 NM_183270
Chchd8
coiled-coil-helix-coiled-coil-helix domain containing 8
chr11_-_62206116 0.799 Ncor1
nuclear receptor co-repressor 1
chr10_+_101621491 0.796 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chr2_-_174289526 0.790 Atp5e
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr12_+_104626888 0.788 NM_026580
NM_001177841
Otub2

OTU domain, ubiquitin aldehyde binding 2

chr5_+_22988226 0.783


chr12_+_30219982 0.775 Myt1l
myelin transcription factor 1-like
chr8_-_47292973 0.770 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr11_+_104189978 0.765 Mapt
microtubule-associated protein tau
chr12_-_42212538 0.763 Lrrn3
leucine rich repeat protein 3, neuronal
chrX_-_147091911 0.756 NM_001002272
NM_019548
Tro

trophinin

chr2_-_65405546 0.739 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_+_69058005 0.711 NM_021331
G6pc2
glucose-6-phosphatase, catalytic, 2
chr10_+_126921038 0.707 R3hdm2
R3H domain containing 2
chr8_-_39724524 0.699 NM_145841
Sgcz
sarcoglycan zeta
chr12_+_110800212 0.683 Meg3
maternally expressed 3
chr7_-_110976438 0.679 Hbb-b1
hemoglobin, beta adult major chain
chr9_+_3335139 0.657 NM_026303
Alkbh8
alkB, alkylation repair homolog 8 (E. coli)
chr13_-_74754745 0.633


chr8_+_115093942 0.620 NM_130457
Cntnap4
contactin associated protein-like 4
chr13_+_14722520 0.618 NM_134067
AW209491
expressed sequence AW209491
chr3_-_115832327 0.614 Vcam1
vascular cell adhesion molecule 1
chr3_-_115956312 0.601 NM_022427
Gpr88
G-protein coupled receptor 88
chr18_+_37133455 0.598 NM_009957
Pcdha7
protocadherin alpha 7
chrM_+_67 0.597


chr6_-_90612275 0.595 Iqsec1
IQ motif and Sec7 domain 1
chr10_-_80693488 0.590 NM_178662
Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr9_-_52484889 0.579 AI593442
expressed sequence AI593442
chr10_-_102698899 0.545 NM_001163559
NM_029134
Lrriq1

leucine-rich repeats and IQ motif containing 1

chr2_+_163899842 0.543 NM_021420
Stk4
serine/threonine kinase 4
chrM_-_14069 0.529 ND6
NADH dehydrogenase subunit 6
chr8_+_73282270 0.525


chr6_+_42236683 0.518 NM_013491
Clcn1
chloride channel 1
chr3_-_65940346 0.509 NM_028357
Veph1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr6_-_119913623 0.503 Wnk1
WNK lysine deficient protein kinase 1
chr11_-_54533036 0.498


chr3_+_13946371 0.491 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chr4_-_134409149 0.479 Tmem57
transmembrane protein 57
chrM_+_1550 0.479


chr2_+_162760505 0.473


chr16_-_85120798 0.473 App
amyloid beta (A4) precursor protein
chr11_-_100576628 0.469


chr9_+_59523404 0.469


chr7_-_125832234 0.466


chr17_+_78907402 0.461 NM_001197028
NM_028813
Vit

vitrin

chr4_-_134409044 0.461 Tmem57
transmembrane protein 57
chr8_+_56040193 0.459 Gpm6a
glycoprotein m6a
chr5_+_122135788 0.456 Brap
BRCA1 associated protein
chr13_-_84204320 0.452 LOC553095
hypothetical LOC553095
chr17_-_45707358 0.452 Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr5_-_101103051 0.444 NM_027978
Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr2_+_13500271 0.443 Vim
vimentin
chr9_-_78326946 0.442 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr2_-_174289569 0.441 NM_025983
Atp5e
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr1_-_180260325 0.439


chr10_+_126503214 0.437 Cdk4
cyclin-dependent kinase 4
chr11_+_117693543 0.434 Afmid
arylformamidase
chr2_-_168478155 0.428 Atp9a
ATPase, class II, type 9A
chr1_+_66368571 0.426 Mtap2
microtubule-associated protein 2
chr10_+_105907394 0.424 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr8_-_47292863 0.423


chr3_+_145541951 0.419


chr5_-_134718500 0.416 Gtf2i
general transcription factor II I
chr10_+_42580317 0.416 NM_172938
Scml4
sex comb on midleg-like 4 (Drosophila)
chr4_-_136891931 0.412 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr2_-_69551514 0.410 Fastkd1
FAST kinase domains 1
chr2_-_37502738 0.400 NM_009261
Strbp
spermatid perinuclear RNA binding protein
chr6_-_51416921 0.390 Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr10_+_20059547 0.389 Bclaf1
BCL2-associated transcription factor 1
chr5_-_114292851 0.389 Coro1c
coronin, actin binding protein 1C
chr19_-_41674337 0.384


chr4_-_118951578 0.376 Ybx1
Y box protein 1
chr12_+_17277227 0.373 Pdia6
protein disulfide isomerase associated 6
chr4_+_109015660 0.370 NM_001159964
Eps15
epidermal growth factor receptor pathway substrate 15
chr18_+_37127284 0.370 NM_007767
Pcdha6
protocadherin alpha 6
chr13_+_14722494 0.368 NM_001104646
AW209491
expressed sequence AW209491
chr16_-_16829386 0.367 NM_015773
Spag6
sperm associated antigen 6
chr4_+_132754604 0.367


chr11_-_50745128 0.365 NM_013744
Zfp354b
zinc finger protein 354B
chr17_+_13208071 0.363 Sod2
superoxide dismutase 2, mitochondrial
chr3_-_108707417 0.361 Prpf38b
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B
chr11_-_97023157 0.360 Kpnb1
karyopherin (importin) beta 1
chr11_-_62190182 0.342 Ncor1
nuclear receptor co-repressor 1
chr13_-_108516475 0.341 Zswim6
zinc finger, SWIM domain containing 6
chr19_-_5797068 0.341


chr16_+_59302980 0.338 NM_146486
Olfr203
olfactory receptor 203
chr15_+_92427539 0.338 NM_001164594
Pdzrn4
PDZ domain containing RING finger 4
chr11_+_87862035 0.335 Srsf1
serine/arginine-rich splicing factor 1
chr13_-_81772121 0.334 NM_054053
Gpr98
G protein-coupled receptor 98
chr4_-_109960078 0.329 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_+_102262447 0.327 NM_001177981
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_8860725 0.325 NM_146092
NM_001177798
Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chr10_-_90612412 0.323 Tmpo
thymopoietin
chr17_-_35971652 0.321 Tubb5
tubulin, beta 5
chr11_-_69229653 0.316 Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr2_+_163051189 0.315 NM_001098799
Tox2
TOX high mobility group box family member 2
chr1_-_192803077 0.309 Vash2
vasohibin 2
chr7_-_140179678 0.309 Ctbp2
C-terminal binding protein 2
chr11_-_41814008 0.305 NM_008073
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr17_-_34251399 0.296 Brd2
bromodomain containing 2
chr18_+_63112372 0.296 Apcdd1
adenomatosis polyposis coli down-regulated 1
chrM_+_7009 0.294 COX2
cytochrome c oxidase subunit II
chr14_+_27473359 0.280 Arf4
ADP-ribosylation factor 4
chr2_+_155576943 0.277 NM_011171
Procr
protein C receptor, endothelial
chr8_-_3154851 0.273 Insr
insulin receptor
chr18_+_37105758 0.272 NM_138662
Pcdha3
protocadherin alpha 3
chr1_-_53409415 0.272 NM_133728
Asnsd1
asparagine synthetase domain containing 1
chr2_+_162760216 0.271 Srsf6
serine/arginine-rich splicing factor 6
chr9_+_120868808 0.269 Ctnnb1
catenin (cadherin associated protein), beta 1
chr1_-_72583137 0.267 NM_001045533
March4
membrane-associated ring finger (C3HC4) 4
chr15_-_76983985 0.265 NM_001110828
NM_001110829
NM_001110830
Rbfox2


RNA binding protein, fox-1 homolog (C. elegans) 2


chr2_+_80193710 0.263


chr11_-_4987973 0.262 Ewsr1
Ewing sarcoma breakpoint region 1
chr17_-_87665228 0.261 NM_139295
NM_176808
Mcfd2

multiple coagulation factor deficiency 2

chr8_-_108462291 0.261 NM_013640
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr11_-_73661624 0.258 NM_147008
Olfr393
olfactory receptor 393
chr4_+_21801372 0.258 Sfrs18
serine/arginine-rich splicing factor 18
chr10_-_8665041 0.258


chr13_+_51245730 0.257


chr7_-_149069070 0.252 Tollip
toll interacting protein
chr8_+_97197870 0.250 Arl2bp
ADP-ribosylation factor-like 2 binding protein
chr11_-_100579201 0.248


chr1_+_66368409 0.247 Mtap2
microtubule-associated protein 2
chr1_+_44040367 0.243 Tpp2
tripeptidyl peptidase II
chrX_-_100381973 0.243 NM_008671
Nap1l2
nucleosome assembly protein 1-like 2
chr15_+_12082671 0.242 Zfr
zinc finger RNA binding protein
chr16_+_20651724 0.239 NM_134101
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr3_+_90145575 0.235 NM_139304
Gatad2b
GATA zinc finger domain containing 2B
chr17_-_85461840 0.235 Prepl
prolyl endopeptidase-like
chr3_-_10208575 0.233 NM_024406
Fabp4
fatty acid binding protein 4, adipocyte
chr10_-_116494883 0.229 Cct2
chaperonin containing Tcp1, subunit 2 (beta)
chr18_+_38611212 0.226


chr9_-_39411708 0.226 NM_178737
AW551984
expressed sequence AW551984
chr4_+_137762192 0.223 Eif4g3
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_146394874 0.223 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr6_-_85019497 0.222 NM_177077
Exoc6b
exocyst complex component 6B
chr17_-_31266539 0.221 NM_011575
Tff3
trefoil factor 3, intestinal
chr2_+_110561733 0.220 NM_172979
Muc15
mucin 15
chr13_+_76718869 0.220 Mctp1
multiple C2 domains, transmembrane 1
chr6_+_90424727 0.217 Klf15
Kruppel-like factor 15
chr4_+_154929136 0.216 Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr2_-_79969095 0.215 NM_016744
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr14_-_111154292 0.213 NM_175499
Slitrk6
SLIT and NTRK-like family, member 6
chr18_+_80315134 0.210 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr16_-_17125198 0.209 NM_183287
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr11_+_75578120 0.207 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr2_-_163450863 0.206 Serinc3
serine incorporator 3
chr5_+_34185760 0.205 NM_001081102
NM_001177884
NM_175231
Whsc1


Wolf-Hirschhorn syndrome candidate 1 (human)


chr18_+_35776026 0.203 Paip2
polyadenylate-binding protein-interacting protein 2
chr5_-_125866485 0.202 Ubc
ubiquitin C
chr14_-_60845511 0.198 BC010981
cDNA sequence BC010981
chr7_+_107423813 0.196 Pgm2l1
phosphoglucomutase 2-like 1
chr7_+_114179649 0.195 NM_147034
Olfr713
olfactory receptor 713
chr4_-_134409199 0.195 Tmem57
transmembrane protein 57
chr2_-_38080023 0.193 8030493G06Rik
RIKEN cDNA 8030493G06 gene

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.