Motif ID: NR5A1,2.p2

Z-value: 3.134

Transcription factors associated with NR5A1,2.p2:

NameEntrezDescription
Nr5a1 26423 nuclear receptor subfamily 5, group A, member 1
Nr5a2 26424 nuclear receptor subfamily 5, group A, member 2



Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr8_-_70342105 24.956 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr18_+_77424573 19.786 NM_013666
NM_153124
St8sia5

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

chr7_-_31699850 19.685 NM_010758
Mag
myelin-associated glycoprotein
chr1_-_137064124 19.051 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr18_+_82723920 18.296 Mbp
myelin basic protein
chr9_-_54509453 17.888 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_+_43851477 17.835 Thy1
thymus cell antigen 1, theta
chr2_-_25174498 16.772 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr4_-_8166182 16.069 NM_007592
Car8
carbonic anhydrase 8
chr5_-_77524256 15.997 NM_001159900
NM_001159901
Hopx

HOP homeobox

chr10_+_75398588 15.886 Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr3_-_87804062 15.796 Bcan
brevican
chr2_+_25118144 14.307 Tprn
taperin
chr9_+_107242932 14.239 NM_175486
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr18_+_82723907 14.128 Mbp
myelin basic protein
chr6_+_114081227 13.900 NM_172890
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr14_+_70857227 13.588 NM_145981
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr2_+_138104219 13.255 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr4_-_82151180 13.229 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr2_-_25174662 12.529 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr10_+_79179326 12.526 NM_008226
Hcn2
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr8_-_87297283 12.357 Nfix
nuclear factor I/X
chr4_-_82151004 12.024 Nfib
nuclear factor I/B
chr15_-_83936038 11.710 Sult4a1
sulfotransferase family 4A, member 1
chr16_+_91270009 11.566 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr4_-_82151657 11.245 Nfib
nuclear factor I/B
chr6_+_90500776 11.051 NM_027406
Aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr2_-_180891448 11.035 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chrX_+_133357268 10.832 NM_011123
Plp1
proteolipid protein (myelin) 1
chr7_-_31699888 10.309 Mag
myelin-associated glycoprotein
chr14_-_104242892 10.097 NM_007904
Ednrb
endothelin receptor type B
chr6_+_117118552 10.066 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr6_+_113232319 9.814 Cpne9
copine family member IX
chr15_+_79921725 9.431 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr3_-_87804277 9.341 NM_001109758
NM_007529
Bcan

brevican

chr19_+_4711220 9.292 NM_021287
Spnb3
spectrin beta 3
chr4_+_97248556 9.246 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr9_-_29770699 8.930 NM_172290
Ntm
neurotrimin
chr7_-_148615247 8.915 NM_021316
Cend1
cell cycle exit and neuronal differentiation 1
chr3_+_27081918 8.888 NM_178772
Nceh1
arylacetamide deacetylase-like 1
chr1_+_174271397 8.857 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr18_+_82723854 8.638 NM_001025251
NM_001025255
NM_001025256
NM_001025258
NM_001025259
NM_001025254
Mbp





myelin basic protein





chr11_-_116515361 8.398 Cygb
cytoglobin
chr6_-_59376283 8.355 NM_183183
Gprin3
GPRIN family member 3
chr3_+_95985065 8.323 NM_022030
Sv2a
synaptic vesicle glycoprotein 2 a
chr2_+_32442585 8.319 St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr3_+_104442568 8.289 NM_009196
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr11_-_72080066 8.238 NM_001004148
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr15_+_3220994 8.184 Sepp1
selenoprotein P, plasma, 1
chr13_+_83663817 8.168 Mef2c
myocyte enhancer factor 2C
chr2_+_129419252 7.919 Sirpa
signal-regulatory protein alpha
chr14_+_122874598 7.820 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr2_-_170232008 7.818 Bcas1
breast carcinoma amplified sequence 1
chr19_+_4711207 7.802 Spnb3
spectrin beta 3
chr15_+_3220999 7.799 Sepp1
selenoprotein P, plasma, 1
chr3_-_36589048 7.710 NM_019510
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr4_-_139802683 7.666 NM_198610
Igsf21
immunoglobin superfamily, member 21
chr10_+_60638341 7.664 Tbata
thymus, brain and testes associated
chr7_+_51846254 7.659 NM_008422
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr7_+_96781228 7.651 Me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_+_53214934 7.522 NM_001164099
NM_001164101
Add3

adducin 3 (gamma)

chr8_+_48072271 7.508 NM_177304
Enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr6_-_113991945 7.458 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr14_-_73785035 7.444 Itm2b
integral membrane protein 2B
chr16_+_18776936 7.333 NM_013805
Cldn5
claudin 5
chr2_-_73749317 7.326 NM_175015
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr7_-_25790888 7.279 NM_144921
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr7_-_88851662 7.194 Homer2
homer homolog 2 (Drosophila)
chr8_+_96676506 7.112 NM_013603
Mt3
metallothionein 3
chr6_-_115201866 7.055 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr9_+_56712850 7.036 NM_139001
Cspg4
chondroitin sulfate proteoglycan 4
chr8_-_13494457 6.985 NM_019521
Gas6
growth arrest specific 6
chr16_+_17276434 6.835 Tmem191c
transmembrane protein 191C
chr18_-_61173753 6.795 NM_201353
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr3_-_117063090 6.677 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr2_+_121184334 6.652 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr6_-_113451811 6.543 NM_172487
Prrt3
proline-rich transmembrane protein 3
chr7_-_135349828 6.543 NM_009943
Cox6a2
cytochrome c oxidase, subunit VI a, polypeptide 2
chr7_-_88851798 6.526 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr4_-_82151590 6.522 Nfib
nuclear factor I/B
chr7_+_19469999 6.399 NM_009402
Pglyrp1
peptidoglycan recognition protein 1
chr5_-_8367951 6.373 NM_001007220
NM_001007221
NM_001098225
Adam22


a disintegrin and metallopeptidase domain 22


chr9_+_123060096 6.323 Clec3b
C-type lectin domain family 3, member b
chr17_-_57199207 6.230 NM_025877
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr2_+_32442620 6.219 St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr11_-_114657186 6.159 NM_028055
Btbd17
BTB (POZ) domain containing 17
chr5_+_107926763 6.132 NM_001007574
NM_001168557
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr1_-_156731538 6.096 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr11_-_116515602 6.064 NM_030206
Cygb
cytoglobin
chr5_+_98683202 5.997 NM_010203
Fgf5
fibroblast growth factor 5
chr14_-_73785068 5.980 NM_008410
Itm2b
integral membrane protein 2B
chr1_-_84692750 5.978 NM_152915
Dner
delta/notch-like EGF-related receptor
chr19_+_8665743 5.949 NM_001164634
NM_031194
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr11_+_29618696 5.901 Rtn4
reticulon 4
chr1_+_36748379 5.882 Cox5b
cytochrome c oxidase, subunit Vb
chr10_+_57514349 5.869 NM_020561
Smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr11_-_116515232 5.802 Cygb
cytoglobin
chr7_-_31514527 5.743 NM_027215
Tmem147
transmembrane protein 147
chr5_-_104542751 5.724 Sparcl1
SPARC-like 1
chr8_-_113917651 5.713 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr6_-_115201846 5.699 Timp4
tissue inhibitor of metalloproteinase 4
chr6_+_38613031 5.628 NM_001101507
Clec2l
C-type lectin domain family, member L
chr9_+_57369014 5.626 NM_007747
Cox5a
cytochrome c oxidase, subunit Va
chr11_-_98636538 5.579 NM_145434
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr9_+_43893029 5.571 Usp2
ubiquitin specific peptidase 2
chr9_-_58160966 5.560 NM_010729
Loxl1
lysyl oxidase-like 1
chr10_-_59414516 5.543 NM_029083
Ddit4
DNA-damage-inducible transcript 4
chr13_+_21879356 5.540 NM_178202
Hist1h2bp
histone cluster 1, H2bp
chrM_+_3320 5.538


chr18_+_78012766 5.462 Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr12_+_103793130 5.336 NM_007693
Chga
chromogranin A
chr11_+_78136681 5.306 Aldoc
aldolase C, fructose-bisphosphate
chr11_+_77744280 5.294 NM_021286
Sez6
seizure related gene 6
chr19_-_40588219 5.266 NM_178362
Sorbs1
sorbin and SH3 domain containing 1
chr5_-_46030523 5.188 NM_021416
Fam184b
family with sequence similarity 184, member B
chr4_-_82150687 5.174 Nfib
nuclear factor I/B
chr11_-_54846882 5.132 NM_001110211
NM_013472
Anxa6

annexin A6

chr15_-_79635156 5.129 Nptxr
neuronal pentraxin receptor
chr2_-_84265422 5.112 NM_018782
Calcrl
calcitonin receptor-like
chr7_+_52419317 5.089 Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr14_-_22668093 5.086 NM_026965
Comtd1
catechol-O-methyltransferase domain containing 1
chr13_-_54867800 5.027 NM_033610
Sncb
synuclein, beta
chr9_-_30978164 5.000 Aplp2
amyloid beta (A4) precursor-like protein 2
chr2_+_121115337 4.921 NM_032393
Mtap1a
microtubule-associated protein 1 A
chr9_-_60497537 4.845 Lrrc49
leucine rich repeat containing 49
chr5_-_104542729 4.830 Sparcl1
SPARC-like 1
chr1_-_169323901 4.830 NM_025569
Mgst3
microsomal glutathione S-transferase 3
chr1_-_136131399 4.826 Adora1
adenosine A1 receptor
chr16_-_95219189 4.810 NM_001025584
NM_001025585
NM_010606
Kcnj6


potassium inwardly-rectifying channel, subfamily J, member 6


chr1_-_84692352 4.805 Dner
delta/notch-like EGF-related receptor
chr5_-_34630913 4.801 NM_001015039
Zfyve28
zinc finger, FYVE domain containing 28
chr2_+_156439426 4.798 NM_146128
Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr19_+_26679649 4.797 NM_011416
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_122874625 4.791 Zic2
zinc finger protein of the cerebellum 2
chr3_-_117063317 4.759 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr16_-_84835213 4.721 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr6_-_136824323 4.672 NM_008597
Mgp
matrix Gla protein
chr9_+_43851466 4.663 NM_009382
Thy1
thymus cell antigen 1, theta
chr2_-_147011990 4.642 NM_001077632
NM_010919
Nkx2-2

NK2 transcription factor related, locus 2 (Drosophila)

chr14_+_14117313 4.612 Synpr
synaptoporin
chr10_-_42722514 4.571 Sobp
sine oculis-binding protein homolog (Drosophila)
chr11_+_68902025 4.496 NM_009497
Vamp2
vesicle-associated membrane protein 2
chrX_-_138740574 4.443 Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr2_+_121973414 4.418 NM_009735
B2m
beta-2 microglobulin
chr10_+_93661746 4.393 NM_025551
Ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr7_-_104566013 4.347 NM_009381
Thrsp
thyroid hormone responsive SPOT14 homolog (Rattus)
chr18_-_61560053 4.340 NM_133249
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr16_+_17276384 4.291 NM_177473
Tmem191c
transmembrane protein 191C
chr5_-_9725274 4.269 NM_181850
Grm3
glutamate receptor, metabotropic 3
chr11_-_95936914 4.224 NM_001161419
NM_007506
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr5_-_104542641 4.221 Sparcl1
SPARC-like 1
chr7_-_53435334 4.217 NM_011510
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr15_+_99223622 4.207 NM_001171035
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr10_+_42221973 4.201 Snx3
sorting nexin 3
chr11_+_68901989 4.190 Vamp2
vesicle-associated membrane protein 2
chr10_-_68004607 4.177 NM_028491
1700040L02Rik
RIKEN cDNA 1700040L02 gene
chr9_+_64949242 4.168 NM_020043
Igdcc4
immunoglobulin superfamily, DCC subclass, member 4
chr7_+_96780900 4.120 Me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr4_+_84851440 4.072 Sh3gl2
SH3-domain GRB2-like 2
chr6_+_54222814 4.050 NM_023543
Chn2
chimerin (chimaerin) 2
chr9_-_40965718 4.018 Ubash3b
ubiquitin associated and SH3 domain containing, B
chr18_+_69843730 4.017 Tcf4
transcription factor 4
chr11_+_119804400 4.009 NM_001037754
NM_001037755
NM_130862
Baiap2


brain-specific angiogenesis inhibitor 1-associated protein 2


chr5_+_150921233 3.999 Fry
furry homolog (Drosophila)
chr8_-_116372637 3.994 NM_172466
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr19_-_23522811 3.986 NM_174857
Mamdc2
MAM domain containing 2
chr2_+_121121189 3.983 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr1_+_164569280 3.975 NM_010865
Myoc
myocilin
chr17_+_37187984 3.952 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr9_+_57787915 3.937 NM_011352
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr1_+_174271338 3.932 NM_001039484
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_127316918 3.901 NM_198632
Trim67
tripartite motif-containing 67
chr13_+_22127689 3.899 NM_175665
Hist1h2bk
histone cluster 1, H2bk
chr7_-_116925058 3.884 NM_020610
Nrip3
nuclear receptor interacting protein 3
chr4_-_126430511 3.858 NM_011986
Ncdn
neurochondrin
chr19_+_21346734 3.845 NM_009551
Zfand5
zinc finger, AN1-type domain 5
chr18_-_13020914 3.805 Osbpl1a
oxysterol binding protein-like 1A
chr2_-_127346987 3.776 Kcnip3
Kv channel interacting protein 3, calsenilin
chr17_+_31523178 3.756 NM_001163748
NM_008804
Pde9a

phosphodiesterase 9A

chr7_-_25757587 3.729 NM_010261
Rabac1
Rab acceptor 1 (prenylated)
chr9_-_53418394 3.712 NM_144784
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr19_-_40588193 3.683 Sorbs1
sorbin and SH3 domain containing 1
chr9_+_45820886 3.638 NM_027498
Sik3
SIK family kinase 3
chr5_-_138052555 3.633 NM_008788
Pcolce
procollagen C-endopeptidase enhancer protein
chrX_+_20265590 3.627 NM_011049
Cdk16
cyclin-dependent kinase 16
chr14_-_16271386 3.597 NM_146052
Lrrc3b
leucine rich repeat containing 3B
chr5_-_104542598 3.579 Sparcl1
SPARC-like 1
chr11_-_21270436 3.578 Ugp2
UDP-glucose pyrophosphorylase 2
chr5_+_52755183 3.558 Sod3
superoxide dismutase 3, extracellular
chr9_+_56712829 3.551 Cspg4
chondroitin sulfate proteoglycan 4
chr2_+_164611444 3.550 NM_133924
Snx21
sorting nexin family member 21
chrM_+_3913 3.546


chr2_+_149656518 3.531 NM_001085521
Tmem90b
transmembrane protein 90B
chr2_-_167318313 3.495 NM_170756
Spata2
spermatogenesis associated 2
chr15_+_22966203 3.486 NM_001081299
Cdh18
cadherin 18
chr5_-_108863376 3.469 NM_007507
Atp5k
ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e
chr9_-_70504934 3.455 NM_172772
Fam63b
family with sequence similarity 63, member B
chr17_-_45686604 3.441 NM_001013749
Tmem151b
transmembrane protein 151B
chr10_+_128370814 3.429 NM_008398
Itga7
integrin alpha 7
chr4_-_115817140 3.406 NM_026547
1520402A15Rik
RIKEN cDNA 1520402A15 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.77 1.57e-07 GO:0006810 transport
1.76 2.26e-07 GO:0051234 establishment of localization
1.66 5.94e-07 GO:0051179 localization
2.43 3.98e-06 GO:0022008 neurogenesis
2.16 4.08e-06 GO:0007399 nervous system development
3.95 9.68e-06 GO:0006091 generation of precursor metabolites and energy
19.21 3.43e-05 GO:0015985 energy coupled proton transport, down electrochemical gradient
19.21 3.43e-05 GO:0015986 ATP synthesis coupled proton transport
3.01 3.57e-05 GO:0044057 regulation of system process
2.60 4.74e-05 GO:0006812 cation transport
2.29 1.15e-04 GO:0006811 ion transport
3.65 1.72e-04 GO:0031644 regulation of neurological system process
3.90 1.97e-04 GO:0050804 regulation of synaptic transmission
2.32 2.12e-04 GO:0051049 regulation of transport
2.92 3.18e-04 GO:0007610 behavior
1.64 4.17e-04 GO:0048731 system development
2.91 5.48e-04 GO:0051050 positive regulation of transport
1.79 6.56e-04 GO:0044281 small molecule metabolic process
3.62 7.04e-04 GO:0051969 regulation of transmission of nerve impulse
6.89 7.68e-04 GO:0006754 ATP biosynthetic process
2.39 9.34e-04 GO:0048878 chemical homeostasis
2.21 1.13e-03 GO:0048699 generation of neurons
1.31 1.66e-03 GO:0044237 cellular metabolic process
1.79 2.39e-03 GO:0051239 regulation of multicellular organismal process
5.56 2.57e-03 GO:0048167 regulation of synaptic plasticity
2.58 2.87e-03 GO:0055082 cellular chemical homeostasis
2.94 3.02e-03 GO:0034220 ion transmembrane transport
2.85 3.32e-03 GO:0019226 transmission of nerve impulse
2.85 3.32e-03 GO:0035637 multicellular organismal signaling
1.80 3.33e-03 GO:0023051 regulation of signaling
1.70 3.37e-03 GO:0065008 regulation of biological quality
19.82 3.45e-03 GO:0006734 NADH metabolic process
1.62 3.77e-03 GO:0048523 negative regulation of cellular process
1.27 3.79e-03 GO:0008152 metabolic process
2.25 4.07e-03 GO:0007154 cell communication
5.86 4.15e-03 GO:0009206 purine ribonucleoside triphosphate biosynthetic process
5.77 4.83e-03 GO:0009145 purine nucleoside triphosphate biosynthetic process
5.77 4.83e-03 GO:0009201 ribonucleoside triphosphate biosynthetic process
2.56 4.84e-03 GO:0006873 cellular ion homeostasis
5.61 6.48e-03 GO:0009142 nucleoside triphosphate biosynthetic process
1.91 6.93e-03 GO:0010646 regulation of cell communication
1.16 7.36e-03 GO:0009987 cellular process
1.52 7.37e-03 GO:0048856 anatomical structure development
2.84 8.76e-03 GO:0015672 monovalent inorganic cation transport
1.91 1.04e-02 GO:0032879 regulation of localization
2.93 1.29e-02 GO:0045664 regulation of neuron differentiation
4.09 1.47e-02 GO:0006164 purine nucleotide biosynthetic process
8.92 1.64e-02 GO:0009109 coenzyme catabolic process
3.82 1.64e-02 GO:0007626 locomotory behavior
4.34 1.65e-02 GO:0022900 electron transport chain
1.47 1.73e-02 GO:0007275 multicellular organismal development
1.45 1.82e-02 GO:0032502 developmental process
7.32 1.83e-02 GO:0043648 dicarboxylic acid metabolic process
4.26 2.02e-02 GO:0015980 energy derivation by oxidation of organic compounds
10.70 2.31e-02 GO:0006099 tricarboxylic acid cycle
8.32 2.69e-02 GO:0050433 regulation of catecholamine secretion
2.65 2.71e-02 GO:0050767 regulation of neurogenesis
2.34 2.79e-02 GO:0050801 ion homeostasis
5.33 2.87e-02 GO:0043270 positive regulation of ion transport
2.30 2.89e-02 GO:0030001 metal ion transport
2.07 2.96e-02 GO:0055085 transmembrane transport
1.53 3.03e-02 GO:0048519 negative regulation of biological process
3.84 3.06e-02 GO:0072522 purine-containing compound biosynthetic process
10.19 3.16e-02 GO:0046356 acetyl-CoA catabolic process
2.24 3.74e-02 GO:0019725 cellular homeostasis
1.76 3.75e-02 GO:0009056 catabolic process
4.67 3.91e-02 GO:0009152 purine ribonucleotide biosynthetic process
1.92 4.07e-02 GO:0042592 homeostatic process
3.36 4.32e-02 GO:0042391 regulation of membrane potential

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.69 2.41e-18 GO:0044444 cytoplasmic part
1.50 4.28e-18 GO:0005737 cytoplasm
3.41 1.65e-12 GO:0043005 neuron projection
2.32 3.68e-12 GO:0005739 mitochondrion
1.30 4.03e-12 GO:0005622 intracellular
1.31 4.81e-12 GO:0044424 intracellular part
2.58 7.26e-12 GO:0042995 cell projection
3.52 1.94e-11 GO:0045202 synapse
4.09 2.17e-10 GO:0005743 mitochondrial inner membrane
3.54 3.67e-10 GO:0005740 mitochondrial envelope
2.37 3.92e-10 GO:0031090 organelle membrane
3.88 1.04e-09 GO:0019866 organelle inner membrane
3.52 1.52e-09 GO:0031966 mitochondrial membrane
4.25 3.15e-09 GO:0030424 axon
3.07 4.12e-09 GO:0044429 mitochondrial part
1.32 4.63e-09 GO:0043229 intracellular organelle
1.31 6.97e-09 GO:0043226 organelle
1.16 1.55e-08 GO:0005623 cell
1.16 1.55e-08 GO:0044464 cell part
1.61 2.88e-08 GO:0071944 cell periphery
1.62 4.17e-08 GO:0005886 plasma membrane
1.33 6.05e-08 GO:0016020 membrane
3.54 9.82e-08 GO:0044456 synapse part
1.33 1.20e-07 GO:0043231 intracellular membrane-bounded organelle
2.73 1.35e-07 GO:0031975 envelope
3.76 1.49e-07 GO:0030425 dendrite
1.32 1.54e-07 GO:0043227 membrane-bounded organelle
2.71 2.58e-07 GO:0031967 organelle envelope
2.32 6.15e-07 GO:0005626 insoluble fraction
2.13 8.02e-07 GO:0000267 cell fraction
2.35 8.09e-07 GO:0005624 membrane fraction
5.77 4.22e-06 GO:0008021 synaptic vesicle
16.65 1.91e-05 GO:0045259 proton-transporting ATP synthase complex
1.78 2.93e-05 GO:0044459 plasma membrane part
10.36 3.19e-05 GO:0044304 main axon
3.10 3.57e-05 GO:0043025 neuronal cell body
4.40 4.06e-05 GO:0030136 clathrin-coated vesicle
4.60 4.75e-05 GO:0033267 axon part
5.20 4.94e-05 GO:0044455 mitochondrial membrane part
2.79 5.52e-05 GO:0044463 cell projection part
7.14 8.16e-05 GO:0070469 respiratory chain
2.96 9.70e-05 GO:0044297 cell body
17.84 1.04e-04 GO:0005753 mitochondrial proton-transporting ATP synthase complex
9.84 2.54e-04 GO:0030672 synaptic vesicle membrane
3.87 2.80e-04 GO:0030135 coated vesicle
15.29 3.22e-04 GO:0048786 presynaptic active zone
1.29 4.76e-04 GO:0044425 membrane part
1.41 7.46e-04 GO:0044446 intracellular organelle part
1.40 9.07e-04 GO:0044422 organelle part
6.83 1.45e-03 GO:0005746 mitochondrial respiratory chain
20.38 5.51e-03 GO:0043218 compact myelin
4.67 6.08e-03 GO:0044306 neuron projection terminus
3.23 6.36e-03 GO:0045121 membrane raft
1.67 7.55e-03 GO:0005829 cytosol
9.31 8.73e-03 GO:0043209 myelin sheath
17.84 1.08e-02 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
4.76 1.22e-02 GO:0044309 neuron spine
1.81 1.73e-02 GO:0044421 extracellular region part
6.75 1.78e-02 GO:0016469 proton-transporting two-sector ATPase complex
4.30 2.94e-02 GO:0014069 postsynaptic density
5.29 3.33e-02 GO:0030665 clathrin coated vesicle membrane
1.89 4.60e-02 GO:0005615 extracellular space
12.97 4.75e-02 GO:0060076 excitatory synapse
3.10 4.99e-02 GO:0045211 postsynaptic membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
5.10 6.10e-10 GO:0022890 inorganic cation transmembrane transporter activity
1.50 6.70e-10 GO:0005515 protein binding
1.27 9.08e-09 GO:0005488 binding
5.58 9.34e-09 GO:0015077 monovalent inorganic cation transmembrane transporter activity
3.12 3.15e-08 GO:0008324 cation transmembrane transporter activity
7.32 1.73e-07 GO:0015078 hydrogen ion transmembrane transporter activity
2.64 4.50e-07 GO:0015075 ion transmembrane transporter activity
2.37 6.11e-07 GO:0022892 substrate-specific transporter activity
2.48 7.23e-07 GO:0022891 substrate-specific transmembrane transporter activity
2.21 1.29e-06 GO:0005215 transporter activity
2.33 3.23e-06 GO:0022857 transmembrane transporter activity
12.59 1.93e-03 GO:0004129 cytochrome-c oxidase activity
12.59 1.93e-03 GO:0015002 heme-copper terminal oxidase activity
12.59 1.93e-03 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
11.89 2.83e-03 GO:0016675 oxidoreductase activity, acting on a heme group of donors
5.23 3.15e-03 GO:0008081 phosphoric diester hydrolase activity
3.68 2.33e-02 GO:0046873 metal ion transmembrane transporter activity
1.97 2.52e-02 GO:0016491 oxidoreductase activity
2.39 2.56e-02 GO:0030246 carbohydrate binding
2.42 2.87e-02 GO:0032403 protein complex binding
3.29 4.23e-02 GO:0001871 pattern binding
3.29 4.23e-02 GO:0030247 polysaccharide binding