• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: NR6A1.p2

Z-value: 1.257

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr4_-_8166182	25.756	NM_007592	Car8	carbonic anhydrase 8
chr4_-_82151657	15.446		Nfib	nuclear factor I/B
chr2_-_25174498	14.451		Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr4_-_82151180	12.863	NM_001113209 NM_001113210 NM_008687	Nfib	nuclear factor I/B
chr4_-_82151004	12.106		Nfib	nuclear factor I/B
chr2_-_25174662	11.247	NM_001177656 NM_001177657 NM_008169	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr3_+_98084352	9.797	NM_008256	Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr16_+_17276434	9.590		Tmem191c	transmembrane protein 191C
chr7_+_17529961	9.294	NM_001099636	Pnmal2	PNMA-like 2
chr2_+_32442585	8.058		St6galnac4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr4_-_82151590	7.944		Nfib	nuclear factor I/B
chr16_+_17276384	7.452	NM_177473	Tmem191c	transmembrane protein 191C
chr13_-_105844882	7.135	NM_029879	Rgs7bp	regulator of G-protein signalling 7 binding protein
chr10_+_96942181	6.878		Dcn	decorin
chr1_-_137064124	6.359	NM_134438	Gpr37l1	G protein-coupled receptor 37-like 1
chr4_-_82150687	6.041		Nfib	nuclear factor I/B
chr2_+_32442620	5.402		St6galnac4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr7_+_19469999	5.375	NM_009402	Pglyrp1	peptidoglycan recognition protein 1
chr2_+_32462471	5.043	NM_001025310 NM_016973	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_79855177	4.839		Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2
chr8_-_109927080	4.546	NM_008706	Nqo1	NAD(P)H dehydrogenase, quinone 1
chr11_-_99105293	4.528	NM_172946	Krt222	keratin 222
chr10_+_96942263	4.430		Dcn	decorin
chr1_-_79855209	4.296		Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2
chr8_-_73284771	4.257	NM_183170	Mpv17l2	MPV17 mitochondrial membrane protein-like 2
chr7_-_90883999	4.096	NM_010551	Il16	interleukin 16
chr3_-_9833502	3.704	NM_001195031 NM_053182	Pag1	phosphoprotein associated with glycosphingolipid microdomains 1
chr15_+_99869071	3.605	NM_001159361	Dip2b	DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr6_+_135148004	3.596	NM_028982	8430419L09Rik	RIKEN cDNA 8430419L09 gene
chr8_+_73278577	3.452	NM_001166399 NM_009001	Rab3a	RAB3A, member RAS oncogene family
chr9_+_27598531	3.429		Opcml	opioid binding protein/cell adhesion molecule-like
chr7_+_17530050	3.411		Pnmal2	PNMA-like 2
chr5_-_124637176	3.171		Pitpnm2	phosphatidylinositol transfer protein, membrane-associated 2
chr2_+_181414995	2.976	NM_009326	Tcea2	transcription elongation factor A (SII), 2
chr4_-_8166157	2.835		Car8	carbonic anhydrase 8
chr7_-_148067703	2.512	NM_001127351 NM_001177804	Sirt3	sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)
chr7_-_135349828	2.246	NM_009943	Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2
chr13_-_12553652	2.225		Lgals8	lectin, galactose binding, soluble 8
chr5_-_138052555	2.162	NM_008788	Pcolce	procollagen C-endopeptidase enhancer protein
chr8_+_72607402	2.099	NM_177900	Hapln4	hyaluronan and proteoglycan link protein 4
chr1_-_83404659	2.060	NM_172430	Sphkap	SPHK1 interactor, AKAP domain containing
chr7_-_30980042	2.025	NM_009795	Capns1	calpain, small subunit 1
chr7_-_53435334	1.996	NM_011510	Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr10_+_122116066	1.896		Ppm1h	protein phosphatase 1H (PP2C domain containing)
chr6_-_60778740	1.856	NM_001042451	Snca	synuclein, alpha
chr5_-_5694033	1.846	NM_001103156 NM_001103157	Steap2	six transmembrane epithelial antigen of prostate 2
chr9_+_106073523	1.830		Wdr82	WD repeat domain containing 82
chr11_+_69659873	1.791	NM_001168497	Plscr3	phospholipid scramblase 3
chr1_+_34858544	1.786	NM_183019	Arhgef4	Rho guanine nucleotide exchange factor (GEF) 4
chr10_+_79167255	1.775		Bsg	basigin
chr18_+_65047408	1.745	NM_001114386	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like
chr17_+_34766489	1.627	NM_030890	Prrt1	proline-rich transmembrane protein 1
chr1_-_66909822	1.616	NM_007381	Acadl	acyl-Coenzyme A dehydrogenase, long-chain
chr15_-_75921924	1.611		Nrbp2	nuclear receptor binding protein 2
chr12_-_72237590	1.608	NM_001024853 NM_001024854 NM_013896	Timm9	translocase of inner mitochondrial membrane 9 homolog (yeast)
chr10_-_68004607	1.581	NM_028491	1700040L02Rik	RIKEN cDNA 1700040L02 gene
chr10_+_80318009	1.565	NM_175195	3110056O03Rik	RIKEN cDNA 3110056O03 gene
chr6_+_42195911	1.405	NM_029555	Gstk1	glutathione S-transferase kappa 1
chr8_+_41947720	1.389	NM_007514 NM_001044740	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_-_25922419	1.337		Haghl	hydroxyacylglutathione hydrolase-like
chr11_-_100632238	1.313	NM_031871	Ghdc	GH3 domain containing
chr7_+_31099832	1.309	NM_153577	AI428936	expressed sequence AI428936
chr11_+_8948594	1.236	NM_001037928	Gm11992	predicted gene 11992
chr17_-_25073798	1.230		Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3
chr8_+_65430028	1.216	NM_023689	Spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr15_+_58720783	1.204	NM_175226	Tatdn1 Rnf139	TatD DNase domain containing 1 ring finger protein 139
chr12_+_4776100	1.200	NM_028376	Pfn4	profilin family, member 4
chr11_+_75813413	1.134	NM_198637	1700016K19Rik	RIKEN cDNA 1700016K19 gene
chr7_+_16705217	1.124	NM_133727	Kptn	kaptin
chr5_-_115934305	1.114	NM_001167691 NM_133760	Sirt4	sirtuin 4 (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)
chr11_-_74982551	1.110		Hic1	hypermethylated in cancer 1
chr17_-_26078825	1.090	NM_011822	Pigq	phosphatidylinositol glycan anchor biosynthesis, class Q
chr18_+_69504145	1.087	NM_013685	Tcf4	transcription factor 4
chr2_-_76511070	1.065	NM_010222	Fkbp7	FK506 binding protein 7
chr2_+_121976718	1.054		B2m	beta-2 microglobulin
chr3_+_27081918	1.038	NM_178772	Nceh1	arylacetamide deacetylase-like 1
chr15_+_73582208	1.021		Ptp4a3	protein tyrosine phosphatase 4a3
chr12_+_3806955	1.011	NM_007872	Dnmt3a	DNA methyltransferase 3A
chr8_+_108939222	1.006	NM_011764	Zfp90	zinc finger protein 90
chr17_+_25960571	0.996	NM_173741	Wdr24	WD repeat domain 24
chr7_-_133520899	0.990		Spns1	spinster homolog 1 (Drosophila)
chr2_+_24909898	0.978	NM_001039386 NM_001039387 NM_001177654 NM_001177655 NM_020276	Nelf	nasal embryonic LHRH factor
chr2_+_91570249	0.972	NM_001080754 NM_172669	Ambra1	autophagy/beclin 1 regulator 1
chr9_+_54434140	0.960	NM_029573	Idh3a	isocitrate dehydrogenase 3 (NAD+) alpha
chr17_-_25073888	0.953		Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3
chr19_+_42245078	0.946		Zfyve27	zinc finger, FYVE domain containing 27
chr10_+_79167197	0.945		Bsg	basigin
chr8_-_127187268	0.943	NM_175149	2310022B05Rik	RIKEN cDNA 2310022B05 gene
chr9_+_65907975	0.921	NM_011149	Ppib	peptidylprolyl isomerase B
chr8_+_125589411	0.912		Spg7	spastic paraplegia 7 homolog (human)
chr5_+_130231000	0.905		Gbas	glioblastoma amplified sequence
chrX_+_162878676	0.904	NM_025432	Trappc2	trafficking protein particle complex 2
chr10_+_42221973	0.875		Snx3	sorting nexin 3
chr1_+_78306890	0.872	NM_001004173	Sgpp2	sphingosine-1-phosphate phosphotase 2
chr5_+_137462888	0.868	NM_011962	Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_17652725	0.853		Nebl	nebulette
chr5_-_37187944	0.846	NM_026242	Mrfap1	Morf4 family associated protein 1
chr9_+_89949315	0.836		Ctsh	cathepsin H
chr8_+_72607355	0.825		Hapln4	hyaluronan and proteoglycan link protein 4
chr7_-_20214596	0.820	NM_009046	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B
chr10_+_79792864	0.806	NM_139292	Reep6	receptor accessory protein 6
chr10_+_80217947	0.797	NM_199322	Dot1l	DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr2_+_131776596	0.777	NM_001126338 NM_023043	Prnd	prion protein dublet
chr18_-_61173753	0.757	NM_201353	Slc6a7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr10_+_79516232	0.754	NM_008162	Gpx4	glutathione peroxidase 4
chr9_+_87039136	0.728	NM_001101482 NM_001177731	Mrap2	melanocortin 2 receptor accessory protein 2
chr15_-_75922055	0.721		Nrbp2	nuclear receptor binding protein 2
chr7_+_138079669	0.716	NM_019564	Htra1	HtrA serine peptidase 1
chr11_-_69476065	0.715		Mpdu1	mannose-P-dolichol utilization defect 1
chr7_+_26404382	0.712	NM_025504	Atp5sl	ATP5S-like
chr6_-_146583036	0.699	NM_026281	Tm7sf3	transmembrane 7 superfamily member 3
chr10_+_34018323	0.678		Tspyl4	TSPY-like 4
chr15_+_82105647	0.676		Sept3	septin 3
chr18_+_75178449	0.658		Dym	dymeclin
chr5_-_135825744	0.644	NM_033571	Fkbp6	FK506 binding protein 6
chr3_+_89070473	0.637	NM_026767	Dpm3	dolichyl-phosphate mannosyltransferase polypeptide 3
chr17_-_74059735	0.634	NM_027864	Galnt14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14
chr19_+_42245160	0.619		Zfyve27	zinc finger, FYVE domain containing 27
chr1_-_172989475	0.618	NM_010188	Fcgr3	Fc receptor, IgG, low affinity III
chr7_+_17545027	0.606	NM_001007569	Pnmal1	PNMA-like 1
chr19_-_46073001	0.603
chr6_-_37249957	0.591	NM_001081206	Dgki	diacylglycerol kinase, iota
chr10_-_80317936	0.589	NM_025349	Lsm7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_+_75178416	0.587	NM_027727	Dym	dymeclin
chr15_+_100299545	0.584		Letmd1	LETM1 domain containing 1
chrX_-_57400778	0.574	NM_133197	Mcf2	mcf.2 transforming sequence
chr4_-_138686896	0.569	NM_001163006	2310028O11Rik	RIKEN cDNA 2310028O11 gene
chr5_+_33361386	0.541	NM_011738	Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr18_+_36440748	0.541	NM_008989	Pura	purine rich element binding protein A
chr19_-_44628193	0.540		Ndufb8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
chr2_+_126896378	0.532	NM_026678	Blvra	biliverdin reductase A
chr8_+_125589362	0.518		Spg7	spastic paraplegia 7 homolog (human)
chr5_+_114453834	0.517	NM_010018	Dao	D-amino acid oxidase
chr17_-_25073897	0.503	NM_001163447 NM_001163448 NM_001163449 NM_001163450 NM_001163451 NM_001163453 NM_013931	Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3
chr6_-_145159310	0.485	NM_177222	Casc1	cancer susceptibility candidate 1
chr13_+_85329102	0.485		Ccnh	cyclin H
chr9_-_123587923	0.485	NM_139142	Slc6a20a	solute carrier family 6 (neurotransmitter transporter), member 20A
chr17_+_34272535	0.468	NM_010386	H2-DMa	histocompatibility 2, class II, locus DMa
chr1_+_153418580	0.464		Fam129a	family with sequence similarity 129, member A
chr10_-_126959446	0.457	NM_028230	Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)
chr4_-_119165183	0.448	NM_177572	Rimkla	ribosomal modification protein rimK-like family member A
chr3_-_88214215	0.447		Pmf1	polyamine-modulated factor 1
chr2_-_127347102	0.436	NM_019789	Kcnip3	Kv channel interacting protein 3, calsenilin
chr14_+_35147355	0.435		Glud1	glutamate dehydrogenase 1
chr12_-_112909656	0.435		Ckb	creatine kinase, brain
chr2_-_174289569	0.429	NM_025983	Atp5e	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr4_-_116300533	0.425	NM_016777	Nasp	nuclear autoantigenic sperm protein (histone-binding)
chr12_-_88488851	0.411	NM_153415	Pomt2	protein-O-mannosyltransferase 2
chr19_-_57389371	0.408		Ablim1	actin-binding LIM protein 1
chr18_+_78017198	0.403
chr2_-_26236126	0.396	NM_172339	Snapc4	small nuclear RNA activating complex, polypeptide 4
chr5_-_122921160	0.386		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr9_+_110322311	0.383	NM_008694	Ngp	neutrophilic granule protein
chr11_-_94900779	0.379		Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2
chr6_+_135312948	0.371	NM_010128	Emp1	epithelial membrane protein 1
chr11_+_81859212	0.370	NM_013654	Ccl7	chemokine (C-C motif) ligand 7
chr1_+_173259275	0.369	NM_001128609 NM_011615	Dedd	death effector domain-containing
chr1_+_58852303	0.364		Casp8	caspase 8
chr19_-_23727286	0.359	NM_026188	1700028P14Rik	RIKEN cDNA 1700028P14 gene
chr11_-_60016324	0.358
chr1_+_176066876	0.353	NM_146721	Olfr424	olfactory receptor 424
chr8_+_107951514	0.347	NM_001033371 NM_001170789	Lrrc36	leucine rich repeat containing 36
chr11_-_22759512	0.346	NM_016888	B3gnt2	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr2_+_121976631	0.344		B2m	beta-2 microglobulin
chr4_-_136441982	0.344	NM_009777	C1qb	complement component 1, q subcomponent, beta polypeptide
chr19_-_3282785	0.344		Ighmbp2	immunoglobulin mu binding protein 2
chr7_+_4971977	0.342	NM_001033383	Zfp865	zinc finger protein 865
chr11_+_117643610	0.340	NM_001195089 NM_001195090 NM_181856	Tmc8	transmembrane channel-like gene family 8
chr8_+_125589407	0.339	NM_153176	Spg7	spastic paraplegia 7 homolog (human)
chr4_-_4065927	0.337		Penk Sdr39u1	preproenkephalin short chain dehydrogenase/reductase family 39U, member 1
chr6_+_128942978	0.335		BC064078	cDNA sequence BC064078
chr17_-_37160143	0.331		Mog	myelin oligodendrocyte glycoprotein
chr6_+_47785659	0.330	NM_027477 NM_173034	Zfp398	zinc finger protein 398
chr15_-_97597988	0.329	NM_001177810 NM_001177811 NM_144850	Rapgef3	Rap guanine nucleotide exchange factor (GEF) 3
chr11_+_72115129	0.327	NM_001037713	Xaf1	XIAP associated factor 1
chr13_-_56397521	0.327		Cxcl14	chemokine (C-X-C motif) ligand 14
chr11_-_101163456	0.322	NM_019584	Becn1	beclin 1, autophagy related
chr8_-_122333845	0.320
chr5_+_130230890	0.316	NM_008095	Gbas	glioblastoma amplified sequence
chr18_-_73914084	0.312	NM_053255	Elac1	elaC homolog 1 (E. coli)
chr5_+_32780438	0.307		Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform
chr11_+_77276081	0.307		Coro6	coronin 6
chr4_-_109149274	0.301		Rnf11	ring finger protein 11
chrX_-_133572810	0.292	NM_001082412	Mcart6	mitochondrial carrier triple repeat 6
chr5_+_31224206	0.292	NM_008439	Khk	ketohexokinase
chr15_-_75724685	0.282		Naprt1	nicotinate phosphoribosyltransferase domain containing 1
chr6_-_122806042	0.274		C3ar1	complement component 3a receptor 1
chr4_+_140924106	0.274	NM_001085513	Fam131c	family with sequence similarity 131, member C
chrX_-_16394443	0.273	NM_172778	Maob	monoamine oxidase B
chr19_-_7292057	0.271		Cox8a	cytochrome c oxidase, subunit VIIIa
chr6_+_114081375	0.270		Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr7_+_29572956	0.267		Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
chr7_-_135137189	0.264		Pycard	PYD and CARD domain containing
chr6_+_3954225	0.263		Gng11	guanine nucleotide binding protein (G protein), gamma 11
chr7_-_20300595	0.262		Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_25101619	0.261	NM_009568	Zfp94	zinc finger protein 94
chr5_+_124562306	0.258	NM_025671	Ogfod2	2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr2_+_91570304	0.256		Ambra1	autophagy/beclin 1 regulator 1
chr10_+_122116022	0.254
chr14_+_21113911	0.251	NM_026341	Nudt13	nudix (nucleoside diphosphate linked moiety X)-type motif 13

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
36.56	2.93e-02	GO:0045814	negative regulation of gene expression, epigenetic

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
11.65	1.28e-03	GO:0000139	Golgi membrane
3.69	1.81e-03	GO:0031090	organelle membrane
1.47	7.19e-03	GO:0044424	intracellular part
10.44	1.20e-02	GO:0030136	clathrin-coated vesicle
1.44	1.40e-02	GO:0005622	intracellular
1.59	1.61e-02	GO:0005737	cytoplasm
4.00	1.77e-02	GO:0012505	endomembrane system
9.19	2.19e-02	GO:0030135	coated vesicle
87.02	2.34e-02	GO:0030288	outer membrane-bounded periplasmic space
87.02	2.34e-02	GO:0042597	periplasmic space
24.71	2.53e-02	GO:0030173	integral to Golgi membrane
24.71	2.53e-02	GO:0031228	intrinsic to Golgi membrane
12.32	3.26e-02	GO:0008021	synaptic vesicle
6.34	3.73e-02	GO:0044431	Golgi apparatus part
60.92	4.97e-02	GO:0030313	cell envelope
60.92	4.97e-02	GO:0044462	external encapsulating structure part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
13.45	4.73e-04	GO:0005539	glycosaminoglycan binding
12.04	8.97e-04	GO:0001871	pattern binding
12.04	8.97e-04	GO:0030247	polysaccharide binding
6.53	2.48e-03	GO:0030246	carbohydrate binding
8.47	2.69e-02	GO:0050662	coenzyme binding