Motif ID: NRF1.p2

Z-value: 4.952

Transcription factors associated with NRF1.p2:

NameEntrezDescription
Nrf1 18181 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Nrf1chr6_+_299979720.521.0e-03Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Description
chr11_+_50191220 18.956 NM_021510
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chr10_+_79144868 18.691 NM_177613
Cdc34
cell division cycle 34 homolog (S. cerevisiae)
chr13_+_14705508 17.443 NM_008944
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr11_-_33063024 14.941 NM_008722
Npm1
nucleophosmin 1
chr14_-_65881225 14.874 NM_021458
Fzd3
frizzled homolog 3 (Drosophila)
chr2_+_160471623 13.669 NM_009408
Top1
topoisomerase (DNA) I
chr17_+_35031503 12.873 NM_198886
Zbtb12
zinc finger and BTB domain containing 12
chr5_+_125343060 12.753 NM_001081750
Zfp664
zinc finger protein 664
chrX_-_91787353 12.595 Maged1
melanoma antigen, family D, 1
chr17_-_48548973 12.443 NM_001110832
NM_010913
Nfya

nuclear transcription factor-Y alpha

chr7_+_25292105 12.426 NM_146183
Zfp428
zinc finger protein 428
chr2_+_156546758 12.090 Dlgap4
discs, large homolog-associated protein 4 (Drosophila)
chr1_-_167932735 11.976 NM_011137
NM_198932
Pou2f1

POU domain, class 2, transcription factor 1

chr7_+_52071622 11.969 NM_001171024
NM_053074
Nup62-il4i1
Nup62
Nup62-Il4i1 protein
nucleoporin 62
chr2_-_24775083 11.893 NM_001012518
NM_001109686
NM_001109687
NM_172545
Ehmt1



euchromatic histone methyltransferase 1



chr18_+_80403581 11.845 NM_178604
Txnl4a
thioredoxin-like 4A
chr14_+_73542810 10.798 Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_-_116661519 10.725 NM_026570
Yeats4
YEATS domain containing 4
chr14_-_21000972 10.336 NM_021542
Kcnk5
potassium channel, subfamily K, member 5
chr11_+_97177029 10.307 NM_025927
Mrpl45
mitochondrial ribosomal protein L45
chr14_-_104867215 10.121 NM_011143
Pou4f1
POU domain, class 4, transcription factor 1
chr14_+_73542866 10.091 Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr18_+_80403500 9.961 NM_001038608
NM_025299
Txnl4a

thioredoxin-like 4A

chr7_+_13609719 9.709 Trim28
tripartite motif-containing 28
chr5_+_77739506 9.700 NM_153798
Polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr5_+_125343129 9.688 Zfp664
zinc finger protein 664
chr10_+_62706550 9.648 Herc4
hect domain and RLD 4
chr6_-_39156706 9.305 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr7_-_4610551 8.965 NM_172894
Ppp6r1
protein phosphatase 6, regulatory subunit 1
chr7_-_29766721 8.802 NM_028659
Eif3k
eukaryotic translation initiation factor 3, subunit K
chr11_-_62602910 8.716 NM_138949
Zfp286
zinc finger protein 286
chr9_-_59598416 8.672 NM_001172068
NM_001172069
NM_001172070
NM_001172071
NM_027838
Senp8




SUMO/sentrin specific peptidase 8




chr15_+_84753817 8.647 NM_016714
Nup50
nucleoporin 50
chr2_+_160471695 8.600 Top1
topoisomerase (DNA) I
chr11_+_3190334 8.120 NM_019574
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr11_+_43342241 8.059 NM_001045530
Ccnjl
cyclin J-like
chr11_+_118884275 8.008 NM_007623
Cbx2
chromobox homolog 2 (Drosophila Pc class)
chr2_-_174298383 7.960 Slmo2
slowmo homolog 2 (Drosophila)
chr11_-_40546863 7.822 NM_013552
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr9_-_22193577 7.816 Anln
anillin, actin binding protein
chr11_+_69446453 7.804 NM_011814
Fxr2
fragile X mental retardation, autosomal homolog 2
chr19_-_5912757 7.755 NM_011262
Dpf2
D4, zinc and double PHD fingers family 2
chr3_+_133899454 7.627 Cxxc4
CXXC finger 4
chr2_+_120393393 7.615 NM_001177792
NM_001177793
NM_009222
Snap23


synaptosomal-associated protein 23


chr10_-_119913319 7.576 Hmga2
high mobility group AT-hook 2
chr13_-_14705281 7.532 NM_029271
Mrpl32
mitochondrial ribosomal protein L32
chr17_+_46339730 7.468 NM_028198
Xpo5
exportin 5
chr2_+_167328944 7.447 Rnf114
ring finger protein 114
chr18_+_80403577 7.321 Txnl4a
thioredoxin-like 4A
chr17_+_10512744 7.164 B930003M22Rik
RIKEN cDNA B930003M22 gene
chr13_+_74487800 7.157 Ccdc127
coiled-coil domain containing 127
chr12_+_16817741 7.144 E2f6
E2F transcription factor 6
chr11_+_60351469 7.106 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr13_-_29045399 7.031 NM_009238
Sox4
SRY-box containing gene 4
chr13_-_3610328 6.942 NM_134063
BC016423
cDNA sequence BC016423
chr1_-_46910333 6.896 NM_172653
Slc39a10
solute carrier family 39 (zinc transporter), member 10
chr1_-_140753398 6.880 NM_001081226
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr11_+_40547143 6.782 NM_026023
Nudcd2
NudC domain containing 2
chr15_-_31531464 6.777 NM_007637
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr17_-_28759356 6.656 NM_016795
Srpk1
serine/arginine-rich protein specific kinase 1
chr14_+_102053172 6.620 NM_016723
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr15_-_73253534 6.601 Ptk2
PTK2 protein tyrosine kinase 2
chr3_+_88101037 6.569 NM_009836
Cct3
chaperonin containing Tcp1, subunit 3 (gamma)
chr5_+_36827236 6.526 NM_025725
Ccdc96
coiled-coil domain containing 96
chr1_+_174078145 6.509 NM_153555
Dcaf8
DDB1 and CUL4 associated factor 8
chr9_+_74709673 6.454 NM_008262
Onecut1
one cut domain, family member 1
chr2_+_167906462 6.439 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr10_-_79862025 6.429 Mbd3
methyl-CpG binding domain protein 3
chr7_-_17199935 6.417 Grlf1
glucocorticoid receptor DNA binding factor 1
chr16_+_96366980 6.407 NM_207301
Wrb
tryptophan rich basic protein
chr4_-_155366696 6.377 NM_080445
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr2_-_139996251 6.239 NM_001081090
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr10_+_61111331 6.218 NM_026438
Ppa1
pyrophosphatase (inorganic) 1
chr5_-_33617477 6.157 Ctbp1
C-terminal binding protein 1
chr6_+_42214999 6.151 NM_007610
Casp2
caspase 2
chr10_-_75700507 6.149 NM_001077638
NM_133182
Prmt2

protein arginine N-methyltransferase 2

chr12_+_16817772 6.124 E2f6
E2F transcription factor 6
chr11_-_6174828 6.120 NM_134020
Tmed4
transmembrane emp24 protein transport domain containing 4
chrX_+_50265390 6.092 NM_027642
Phf6
PHD finger protein 6
chr8_-_91566329 6.042 Sall1
sal-like 1 (Drosophila)
chr19_-_4397065 6.018 Kdm2a
lysine (K)-specific demethylase 2A
chr4_-_126645421 5.982 Zmym4
zinc finger, MYM-type 4
chr13_-_104968472 5.951 NM_001093759
NM_001093760
NM_025879
2410002O22Rik


RIKEN cDNA 2410002O22 gene


chr11_+_40547368 5.948 Nudcd2
NudC domain containing 2
chr12_+_110691637 5.898 NM_001190703
NM_001190704
NM_001190705
NM_010052
Dlk1



delta-like 1 homolog (Drosophila)



chr10_+_61111426 5.865 Ppa1
pyrophosphatase (inorganic) 1
chr2_+_32092184 5.854 NM_145145
Pomt1
protein-O-mannosyltransferase 1
chr6_-_89312545 5.849 NM_008881
Plxna1
plexin A1
chr4_+_148178500 5.758 NM_001159344
NM_027195
Casz1

castor homolog 1, zinc finger (Drosophila)

chr9_+_64988960 5.751 NM_008988
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr15_-_11329310 5.722 Tars
threonyl-tRNA synthetase
chr1_-_54614516 5.691 NM_001163314
Pgap1
post-GPI attachment to proteins 1
chr7_-_134160841 5.691 2900092E17Rik
RIKEN cDNA 2900092E17 gene
chr6_-_134847832 5.654 NM_001167695
NM_001167696
NM_001167693
NM_001167694
NM_001167700
Gpr19




G protein-coupled receptor 19




chr4_-_44180769 5.635


chr1_+_161162285 5.583 NM_011931
Rfwd2
ring finger and WD repeat domain 2
chr2_+_37307751 5.554 NM_001033960
Rabgap1
RAB GTPase activating protein 1
chr4_+_10801637 5.535 NM_026005
2610301B20Rik
RIKEN cDNA 2610301B20 gene
chr17_-_46817800 5.531 NM_001163729
NM_027910
Klhdc3

kelch domain containing 3

chr3_-_108525202 5.530 NM_029522
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr16_-_90727466 5.527 NM_025642
2610039C10Rik
RIKEN cDNA 2610039C10 gene
chr10_-_117147722 5.522 Mdm2
transformed mouse 3T3 cell double minute 2
chr1_+_39044599 5.519 NM_026850
Pdcl3
phosducin-like 3
chr5_+_28492235 5.479 NM_010134
En2
engrailed 2
chr1_-_37921891 5.446 NM_207228
Tsga10
testis specific 10
chr7_+_13609462 5.443 NM_011588
Trim28
tripartite motif-containing 28
chr9_+_108594470 5.416 NM_008924
Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha
chr2_+_119722957 5.403 NM_001164274
NM_013720
Mga

MAX gene associated

chr1_-_42751652 5.360 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr11_+_59263522 5.329 NM_178659
Jmjd4
jumonji domain containing 4
chr7_+_4610254 5.299


chr2_-_25838722 5.273 NM_001115076
Camsap1
calmodulin regulated spectrin-associated protein 1
chr14_+_32149804 5.271 NM_009796
Capn7
calpain 7
chr4_-_88368313 5.242 NM_172871
Klhl9
kelch-like 9 (Drosophila)
chr19_-_7557678 5.240 Rtn3
reticulon 3
chr2_+_157385835 5.204 NM_010923
NM_180960
Nnat

neuronatin

chr8_-_9976197 5.197 NM_176953
Lig4
ligase IV, DNA, ATP-dependent
chr10_+_58786043 5.180 NM_011030
P4ha1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr15_-_73253617 5.170 NM_001130409
NM_007982
Ptk2

PTK2 protein tyrosine kinase 2

chr9_+_21420612 5.162 NM_001174078
NM_001174079
NM_011417
Smarca4


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4


chr4_-_45421590 5.150 NM_001009949
Mcart1
mitochondrial carrier triple repeat 1
chr2_+_167328880 5.119 Rnf114
ring finger protein 114
chr5_+_124778178 5.085 2810006K23Rik
RIKEN cDNA 2810006K23 gene
chr17_-_23810808 5.082 Thoc6
THO complex 6 homolog (Drosophila)
chr3_-_108525060 5.070 Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr11_-_86071041 5.067 NM_027421
Ints2
integrator complex subunit 2
chr11_+_77796215 5.066 NM_174852
Phf12
PHD finger protein 12
chr19_+_5490454 5.064 NM_007687
Cfl1
cofilin 1, non-muscle
chr12_+_16817770 5.048 NM_033270
E2f6
E2F transcription factor 6
chr3_-_138152336 5.046 NM_175224
Metap1
methionyl aminopeptidase 1
chr5_-_33617629 5.028 Ctbp1
C-terminal binding protein 1
chr6_-_77929575 4.996 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_+_10002207 4.976 NM_025280
Kin
antigenic determinant of rec-A protein
chr4_+_123582074 4.976 NM_019660
Mycbp
c-myc binding protein
chrX_+_54307050 4.963 Htatsf1
HIV TAT specific factor 1
chr11_+_86358491 4.945 NM_001199045
NM_001199046
NM_001199047
NM_019756
Tubd1



tubulin, delta 1



chr2_-_120389559 4.931 NM_011743
Zfp106
zinc finger protein 106
chr17_+_74738195 4.919 NM_001162870
NM_016962
Spast

spastin

chr17_+_35272395 4.878 Bag6
BCL2-associated athanogene 6
chr6_+_83864346 4.854 NM_001166371
NM_008717
Zfml

zinc finger, matrin-like

chr17_-_80606644 4.836 NM_001195485
NM_001195486
NM_001195487
NM_146083
Srsf7



serine/arginine-rich splicing factor 7



chr4_-_154010868 4.795 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr2_+_37307786 4.776 Rabgap1
RAB GTPase activating protein 1
chr11_+_59021811 4.767 NM_024210
2310033P09Rik
RIKEN cDNA 2310033P09 gene
chr17_-_80606526 4.766 Srsf7
serine/arginine-rich splicing factor 7
chr9_+_119354040 4.761 NM_001172136
NM_172456
Exog

endo/exonuclease (5'-3'), endonuclease G-like

chr12_+_31596533 4.738 NM_013709
Sh3yl1
Sh3 domain YSC-like 1
chr4_-_117963950 4.736 NM_011213
Ptprf
protein tyrosine phosphatase, receptor type, F
chr9_-_26962964 4.733 NM_023277
Jam3
junction adhesion molecule 3
chr4_-_120242805 4.676 NM_016748
Ctps
cytidine 5'-triphosphate synthase
chr5_-_33617631 4.672 NM_001198859
NM_001198860
NM_001198861
NM_013502
Ctbp1



C-terminal binding protein 1



chrX_+_96331434 4.665 NM_010110
Efnb1
ephrin B1
chr15_-_83425479 4.664 NM_183017
Ttll12
tubulin tyrosine ligase-like family, member 12
chr15_-_103070291 4.660


chr19_+_41557475 4.627 Lcor
ligand dependent nuclear receptor corepressor
chr6_-_146526247 4.625 NM_138757
4933424B01Rik
RIKEN cDNA 4933424B01 gene
chr7_-_148599956 4.614 NM_172116
Pddc1
Parkinson disease 7 domain containing 1
chr15_-_51823107 4.586 Rad21
RAD21 homolog (S. pombe)
chr4_+_131830270 4.585 NM_025579
Taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_+_74674793 4.574 NM_153406
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr13_+_68721096 4.563 NM_027123
Fastkd3
FAST kinase domains 3
chr1_+_136391318 4.550 Rabif
RAB interacting factor
chr2_+_157854192 4.528 Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr18_+_6765174 4.519 NM_181070
Rab18
RAB18, member RAS oncogene family
chr1_-_130488785 4.498 NM_009911
Cxcr4
chemokine (C-X-C motif) receptor 4
chr10_+_59465552 4.498 NM_026937
Ascc1
activating signal cointegrator 1 complex subunit 1
chr7_+_25292201 4.492 Zfp428
zinc finger protein 428
chr10_-_119913204 4.483 Hmga2
high mobility group AT-hook 2
chr6_-_39156609 4.482 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr12_+_99985150 4.477 NM_001008506
NM_001160107
NM_029334
Zc3h14


zinc finger CCCH type containing 14


chrX_+_148667763 4.468 NM_013668
Kdm5c
lysine (K)-specific demethylase 5C
chr2_+_21127350 4.467 NM_001001297
NM_177588
Thnsl1

threonine synthase-like 1 (bacterial)

chr7_-_105805050 4.460 NM_172280
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr15_-_73253659 4.431 Ptk2
PTK2 protein tyrosine kinase 2
chr6_-_118512232 4.422 NM_001081112
Ankrd26
ankyrin repeat domain 26
chr18_-_37803782 4.418 NM_175770
Taf7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_-_79502432 4.412 Polr2e
polymerase (RNA) II (DNA directed) polypeptide E
chr11_+_57917469 4.390 NM_026949
Cnot8
CCR4-NOT transcription complex, subunit 8
chr3_-_154756325 4.386 NM_029330
Fpgt
fucose-1-phosphate guanylyltransferase
chr16_+_94592373 4.379 Ttc3
tetratricopeptide repeat domain 3
chr8_+_72758479 4.368 Sugp2
SURP and G patch domain containing 2
chr1_+_53353919 4.365 NM_145517
Ormdl1
ORM1-like 1 (S. cerevisiae)
chr1_-_133034721 4.333 NM_145508
Dyrk3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr1_-_55144637 4.317 Hspd1
heat shock protein 1 (chaperonin)
chr2_-_136942066 4.314 NM_013822
Jag1
jagged 1
chr8_-_122099015 4.305 Hsdl1
hydroxysteroid dehydrogenase like 1
chr9_+_110034489 4.304 NM_009211
Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr17_-_87665211 4.287 Mcfd2
multiple coagulation factor deficiency 2
chr16_-_45742995 4.280 NM_172511
Abhd10
abhydrolase domain containing 10
chr5_-_137462712 4.277 Znhit1
zinc finger, HIT domain containing 1
chr5_-_92566671 4.268


chr19_-_7315495 4.259 NM_027643
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr3_-_68848588 4.187 Trim59
tripartite motif-containing 59
chr7_+_25315666 4.177 NM_153134
Irgq
immunity-related GTPase family, Q
chr6_+_66485368 4.173 NM_019499
Mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr14_+_73542894 4.158 Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr17_-_87665228 4.155 NM_139295
NM_176808
Mcfd2

multiple coagulation factor deficiency 2

chr15_-_102501463 4.144 NM_026468
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr2_-_164705231 4.142 4930445K14Rik
RIKEN cDNA 4930445K14 gene
chr8_-_87956606 4.131 4921524J17Rik
RIKEN cDNA 4921524J17 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.91 3.89e-51 GO:0044260 cellular macromolecule metabolic process
1.79 1.24e-44 GO:0043170 macromolecule metabolic process
2.19 1.03e-41 GO:0090304 nucleic acid metabolic process
2.03 5.92e-39 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 2.14e-37 GO:0044237 cellular metabolic process
1.91 1.27e-34 GO:0034641 cellular nitrogen compound metabolic process
2.12 1.87e-34 GO:0010467 gene expression
1.57 7.92e-33 GO:0044238 primary metabolic process
2.15 1.14e-32 GO:0016070 RNA metabolic process
1.86 1.68e-32 GO:0006807 nitrogen compound metabolic process
1.48 1.83e-29 GO:0008152 metabolic process
1.97 2.62e-24 GO:0034645 cellular macromolecule biosynthetic process
1.96 9.33e-24 GO:0009059 macromolecule biosynthetic process
1.86 2.15e-17 GO:0071841 cellular component organization or biogenesis at cellular level
1.70 3.44e-17 GO:0044249 cellular biosynthetic process
1.76 5.33e-17 GO:0010468 regulation of gene expression
1.85 6.61e-17 GO:0044267 cellular protein metabolic process
1.78 1.05e-16 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.75 5.96e-16 GO:0010556 regulation of macromolecule biosynthetic process
1.96 6.12e-16 GO:0032774 RNA biosynthetic process
1.63 7.08e-16 GO:0060255 regulation of macromolecule metabolic process
1.72 1.14e-15 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.95 1.16e-15 GO:0006351 transcription, DNA-dependent
1.71 2.20e-15 GO:0051171 regulation of nitrogen compound metabolic process
1.65 2.29e-15 GO:0009058 biosynthetic process
1.83 2.30e-15 GO:0071842 cellular component organization at cellular level
2.89 2.82e-15 GO:0006396 RNA processing
2.48 3.61e-15 GO:0007049 cell cycle
1.59 6.35e-15 GO:0031323 regulation of cellular metabolic process
1.77 8.78e-15 GO:0051252 regulation of RNA metabolic process
1.54 1.04e-14 GO:0019222 regulation of metabolic process
1.77 1.56e-14 GO:0006355 regulation of transcription, DNA-dependent
2.03 1.99e-14 GO:0006996 organelle organization
1.68 4.27e-14 GO:0031326 regulation of cellular biosynthetic process
1.58 5.35e-14 GO:0080090 regulation of primary metabolic process
1.67 1.05e-13 GO:0009889 regulation of biosynthetic process
3.60 2.53e-13 GO:0008380 RNA splicing
1.62 8.80e-13 GO:0071840 cellular component organization or biogenesis
1.65 2.88e-12 GO:0019538 protein metabolic process
1.59 5.53e-11 GO:0016043 cellular component organization
2.67 6.50e-11 GO:0006259 DNA metabolic process
2.59 4.65e-10 GO:0051276 chromosome organization
1.18 1.64e-09 GO:0009987 cellular process
2.65 3.89e-09 GO:0022403 cell cycle phase
2.87 7.63e-09 GO:0051301 cell division
2.36 8.81e-09 GO:0022402 cell cycle process
1.71 5.89e-08 GO:0006464 protein modification process
1.69 8.99e-08 GO:0043412 macromolecule modification
2.72 1.31e-07 GO:0000279 M phase
3.16 2.90e-07 GO:0000280 nuclear division
3.16 2.90e-07 GO:0007067 mitosis
2.57 3.19e-07 GO:0000278 mitotic cell cycle
2.65 3.52e-07 GO:0016071 mRNA metabolic process
3.09 5.80e-07 GO:0000087 M phase of mitotic cell cycle
2.81 6.28e-07 GO:0006281 DNA repair
3.03 9.92e-07 GO:0048285 organelle fission
3.67 1.78e-06 GO:0006913 nucleocytoplasmic transport
3.60 3.00e-06 GO:0051169 nuclear transport
2.56 9.05e-06 GO:0016568 chromatin modification
2.42 1.23e-05 GO:0006325 chromatin organization
2.66 1.31e-05 GO:0006397 mRNA processing
2.02 1.37e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.56 2.11e-05 GO:0051168 nuclear export
1.81 2.54e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.99 2.61e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.57 7.95e-05 GO:0006412 translation
2.01 8.51e-05 GO:0051253 negative regulation of RNA metabolic process
2.01 1.06e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.95 1.16e-04 GO:0010629 negative regulation of gene expression
1.76 1.61e-04 GO:0031324 negative regulation of cellular metabolic process
2.43 1.93e-04 GO:0070647 protein modification by small protein conjugation or removal
2.24 2.17e-04 GO:0006974 response to DNA damage stimulus
1.73 2.28e-04 GO:0051641 cellular localization
1.91 2.39e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.56 2.74e-04 GO:0032446 protein modification by small protein conjugation
1.71 3.07e-04 GO:0009892 negative regulation of metabolic process
1.96 3.81e-04 GO:0046907 intracellular transport
2.16 4.80e-04 GO:0044265 cellular macromolecule catabolic process
1.45 8.17e-04 GO:0048523 negative regulation of cellular process
2.57 8.53e-04 GO:0016567 protein ubiquitination
11.28 9.78e-04 GO:0000726 non-recombinational repair
1.84 1.11e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.58 1.12e-03 GO:0034660 ncRNA metabolic process
6.09 1.53e-03 GO:0006405 RNA export from nucleus
1.87 1.54e-03 GO:0033554 cellular response to stress
13.30 1.64e-03 GO:0006303 double-strand break repair via nonhomologous end joining
2.33 2.13e-03 GO:0033043 regulation of organelle organization
1.40 3.11e-03 GO:0048519 negative regulation of biological process
1.66 3.47e-03 GO:0008104 protein localization
1.78 3.70e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.66 4.41e-03 GO:0016570 histone modification
2.61 6.06e-03 GO:0016569 covalent chromatin modification
2.42 6.40e-03 GO:0007017 microtubule-based process
1.58 7.40e-03 GO:0033036 macromolecule localization
1.70 7.68e-03 GO:0051649 establishment of localization in cell
1.73 8.57e-03 GO:0009890 negative regulation of biosynthetic process
1.64 9.08e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.68 1.00e-02 GO:0050657 nucleic acid transport
3.68 1.00e-02 GO:0050658 RNA transport
3.68 1.00e-02 GO:0051236 establishment of RNA localization
4.63 1.29e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
3.55 1.69e-02 GO:0006403 RNA localization
4.19 1.75e-02 GO:0006367 transcription initiation from RNA polymerase II promoter
5.37 1.78e-02 GO:0000070 mitotic sister chromatid segregation
3.01 1.89e-02 GO:0032259 methylation
2.62 1.89e-02 GO:0051493 regulation of cytoskeleton organization
3.88 2.08e-02 GO:0006302 double-strand break repair
2.55 2.16e-02 GO:0034470 ncRNA processing
1.69 2.24e-02 GO:0051254 positive regulation of RNA metabolic process
9.67 2.33e-02 GO:0046605 regulation of centrosome cycle
1.89 2.52e-02 GO:0009057 macromolecule catabolic process
3.16 2.56e-02 GO:0043414 macromolecule methylation
2.38 2.61e-02 GO:0010564 regulation of cell cycle process
4.34 2.62e-02 GO:0006354 transcription elongation, DNA-dependent
1.63 2.87e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.65 3.63e-02 GO:0006260 DNA replication
1.63 3.81e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.50 4.07e-02 GO:0070936 protein K48-linked ubiquitination
4.92 4.20e-02 GO:0000819 sister chromatid segregation
3.65 4.34e-02 GO:0006352 transcription initiation, DNA-dependent
2.61 4.49e-02 GO:0000226 microtubule cytoskeleton organization
1.50 4.73e-02 GO:0010604 positive regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.97 2.69e-64 GO:0005634 nucleus
1.46 1.12e-62 GO:0005622 intracellular
1.46 6.83e-59 GO:0044424 intracellular part
1.53 1.00e-55 GO:0043229 intracellular organelle
1.53 4.06e-55 GO:0043226 organelle
1.58 1.05e-53 GO:0043231 intracellular membrane-bounded organelle
1.58 2.61e-53 GO:0043227 membrane-bounded organelle
1.87 3.48e-40 GO:0044446 intracellular organelle part
2.48 5.01e-39 GO:0044428 nuclear part
1.84 1.94e-38 GO:0044422 organelle part
2.50 1.12e-31 GO:0031981 nuclear lumen
2.29 3.92e-29 GO:0031974 membrane-enclosed lumen
2.29 3.05e-28 GO:0070013 intracellular organelle lumen
2.29 3.96e-28 GO:0043233 organelle lumen
1.82 6.07e-27 GO:0032991 macromolecular complex
2.57 4.75e-23 GO:0005654 nucleoplasm
1.79 4.02e-20 GO:0043234 protein complex
1.35 3.93e-19 GO:0005737 cytoplasm
1.84 4.43e-19 GO:0043228 non-membrane-bounded organelle
1.84 4.43e-19 GO:0043232 intracellular non-membrane-bounded organelle
2.75 3.15e-18 GO:0044451 nucleoplasm part
3.11 6.25e-17 GO:0005694 chromosome
3.11 1.65e-15 GO:0044427 chromosomal part
1.12 5.47e-10 GO:0005623 cell
1.12 5.47e-10 GO:0044464 cell part
3.34 8.69e-09 GO:0000228 nuclear chromosome
3.29 1.37e-08 GO:0000785 chromatin
3.43 4.32e-08 GO:0044454 nuclear chromosome part
2.24 6.32e-08 GO:0015630 microtubule cytoskeleton
2.34 1.82e-07 GO:0030529 ribonucleoprotein complex
1.70 2.15e-07 GO:0005829 cytosol
5.35 3.28e-07 GO:0000792 heterochromatin
5.11 5.42e-06 GO:0034708 methyltransferase complex
5.11 5.42e-06 GO:0035097 histone methyltransferase complex
2.50 9.87e-06 GO:0005667 transcription factor complex
2.33 1.59e-05 GO:0005730 nucleolus
2.73 3.35e-05 GO:0005815 microtubule organizing center
3.28 4.58e-05 GO:0000775 chromosome, centromeric region
4.43 5.43e-05 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.75 1.03e-04 GO:0005813 centrosome
3.66 1.36e-04 GO:0000790 nuclear chromatin
3.94 1.60e-04 GO:0016585 chromatin remodeling complex
3.77 6.45e-04 GO:0071013 catalytic step 2 spliceosome
3.14 1.68e-03 GO:0005819 spindle
5.13 1.82e-03 GO:0000118 histone deacetylase complex
1.21 3.21e-03 GO:0044444 cytoplasmic part
8.86 7.77e-03 GO:0005665 DNA-directed RNA polymerase II, core complex
1.59 8.81e-03 GO:0044430 cytoskeletal part
6.89 1.16e-02 GO:0000428 DNA-directed RNA polymerase complex
6.89 1.16e-02 GO:0055029 nuclear DNA-directed RNA polymerase complex
8.18 1.37e-02 GO:0005852 eukaryotic translation initiation factor 3 complex
6.53 1.75e-02 GO:0030880 RNA polymerase complex
6.53 1.75e-02 GO:0045120 pronucleus
1.44 1.83e-02 GO:0005856 cytoskeleton
2.65 2.21e-02 GO:0005681 spliceosomal complex
4.32 2.50e-02 GO:0000922 spindle pole
3.09 3.00e-02 GO:0000776 kinetochore
11.82 4.90e-02 GO:0070419 nonhomologous end joining complex

Gene overrepresentation in function category:

enrichment p-value GO term description
2.05 2.87e-32 GO:0003676 nucleic acid binding
1.27 3.92e-19 GO:0005488 binding
2.68 6.87e-18 GO:0003723 RNA binding
1.89 5.23e-15 GO:0003677 DNA binding
1.76 1.39e-13 GO:0000166 nucleotide binding
1.37 2.56e-11 GO:0005515 protein binding
3.41 6.13e-09 GO:0003682 chromatin binding
2.51 9.29e-08 GO:0016874 ligase activity
1.67 9.55e-07 GO:0030554 adenyl nucleotide binding
1.67 1.30e-06 GO:0032559 adenyl ribonucleotide binding
1.88 1.33e-06 GO:0030528 transcription regulator activity
1.67 1.47e-06 GO:0005524 ATP binding
2.77 3.43e-06 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.55 1.48e-05 GO:0017076 purine nucleotide binding
1.56 1.62e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.55 1.96e-05 GO:0032555 purine ribonucleotide binding
1.54 2.03e-05 GO:0032553 ribonucleotide binding
3.71 3.50e-05 GO:0016779 nucleotidyltransferase activity
2.70 5.50e-05 GO:0016881 acid-amino acid ligase activity
1.24 7.13e-04 GO:0003824 catalytic activity
6.65 1.58e-03 GO:0035064 methylated histone residue binding
3.78 1.61e-03 GO:0042393 histone binding
2.40 1.77e-03 GO:0003712 transcription cofactor activity
2.39 1.94e-03 GO:0000989 transcription factor binding transcription factor activity
2.36 2.53e-03 GO:0000988 protein binding transcription factor activity
2.52 2.84e-03 GO:0019787 small conjugating protein ligase activity
2.15 3.36e-03 GO:0016564 transcription repressor activity
1.51 3.59e-03 GO:0008270 zinc ion binding
1.66 3.94e-03 GO:0019899 enzyme binding
2.86 5.65e-03 GO:0004386 helicase activity
2.12 6.03e-03 GO:0008134 transcription factor binding
2.52 6.07e-03 GO:0004842 ubiquitin-protein ligase activity
2.23 6.15e-03 GO:0016887 ATPase activity
1.75 6.59e-03 GO:0016462 pyrophosphatase activity
1.74 7.62e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.73 7.99e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.59 1.11e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.71 2.06e-02 GO:0017111 nucleoside-triphosphatase activity
14.18 2.25e-02 GO:0046974 histone methyltransferase activity (H3-K9 specific)
4.99 2.25e-02 GO:0034061 DNA polymerase activity
4.84 2.94e-02 GO:0003899 DNA-directed RNA polymerase activity
4.84 2.94e-02 GO:0034062 RNA polymerase activity
3.13 3.44e-02 GO:0051082 unfolded protein binding