Motif ID: PATZ1.p2

Z-value: 0.921

Transcription factors associated with PATZ1.p2:

NameEntrezDescription
Patz1 56218 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Patz1chr11_+_31907810.261.3e-01Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr12_+_3891743 5.652 NM_153743
Dnmt3a
DNA methyltransferase 3A
chr7_-_150646883 4.225 NM_001161624
NM_009876
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr4_-_155571450 3.737 Agrn
agrin
chr4_-_44181148 2.688 NM_001038993
Rnf38
ring finger protein 38
chr11_-_95867076 2.475 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr12_-_28027541 2.473 NM_009234
Sox11
SRY-box containing gene 11
chr3_+_127336055 2.302 NM_009718
Neurog2
neurogenin 2
chr11_+_23978029 2.051 NM_001159289
NM_016707
Bcl11a

B-cell CLL/lymphoma 11A (zinc finger protein)

chr11_+_23978110 2.026 Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr1_-_153937097 1.971 1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr2_-_91771836 1.887 NM_001012335
Mdk
midkine
chr15_-_98764960 1.861 Tuba1b
tubulin, alpha 1B
chr4_+_129190877 1.860 Marcksl1
MARCKS-like 1
chr4_-_44180769 1.843


chr11_-_70846926 1.816 6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr19_+_7492081 1.766 NM_175381
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr8_-_126039251 1.740 Dbndd1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr11_-_69182891 1.728 NM_146019
Chd3
chromodomain helicase DNA binding protein 3
chr14_-_60705571 1.715 NM_015803
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr10_+_79642100 1.705 NM_007909
Efna2
ephrin A2
chr1_-_84281164 1.691 NM_001003948
Pid1
phosphotyrosine interaction domain containing 1
chr2_-_91771882 1.666 Mdk
midkine
chr8_-_126039287 1.665 NM_001170975
NM_001170976
NM_028146
Dbndd1


dysbindin (dystrobrevin binding protein 1) domain containing 1


chr11_+_101329615 1.664 NM_009708
Rnd2
Rho family GTPase 2
chr9_+_47338431 1.661 NM_001025600
NM_018770
NM_207675
NM_207676
Cadm1



cell adhesion molecule 1



chr17_+_30142111 1.654 Zfand3
zinc finger, AN1-type domain 3
chr5_+_115879617 1.637 NM_008629
Msi1
Musashi homolog 1(Drosophila)
chr9_-_122203483 1.613 NM_133979
Ano10
anoctamin 10
chr13_-_72101161 1.586 NM_010573
Irx1
Iroquois related homeobox 1 (Drosophila)
chr15_-_76352331 1.557 NM_130893
Scrt1
scratch homolog 1, zinc finger protein (Drosophila)
chr2_-_34227309 1.554 NM_016768
Pbx3
pre B-cell leukemia transcription factor 3
chr1_-_170362278 1.553 Pbx1
pre B-cell leukemia transcription factor 1
chr8_-_94325138 1.535 NM_008393
Irx3
Iroquois related homeobox 3 (Drosophila)
chr10_-_86956393 1.534 NM_008553
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr11_-_102091406 1.529 NM_001077696
NM_010412
Hdac5

histone deacetylase 5

chr3_-_83844042 1.527 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr2_-_76486033 1.525 NM_011871
Prkra
protein kinase, interferon inducible double stranded RNA dependent activator
chr14_-_52634206 1.472 Zfp219
zinc finger protein 219
chr9_-_82868992 1.451 Phip
pleckstrin homology domain interacting protein
chr18_-_16966954 1.428 Cdh2
cadherin 2
chr1_-_90598670 1.423 NM_177305
Arl4c
ADP-ribosylation factor-like 4C
chr15_+_98465193 1.409 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr7_-_35597470 1.377 NM_175140
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr2_+_38206759 1.376 NM_010710
Lhx2
LIM homeobox protein 2
chr13_-_78338131 1.375 NM_010151
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr15_-_88979923 1.373 NM_011161
Mapk11
mitogen-activated protein kinase 11
chr14_+_22320074 1.368 Myst4
MYST histone acetyltransferase monocytic leukemia 4
chr15_-_95358674 1.368 Nell2
NEL-like 2 (chicken)
chr9_-_107612238 1.366 Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_-_138182307 1.361 6430598A04Rik
RIKEN cDNA 6430598A04 gene
chr12_-_60112987 1.358 NM_009147
Sec23a
SEC23A (S. cerevisiae)
chr8_+_125935441 1.323 NM_023279
Tubb3
tubulin, beta 3
chr7_+_108966826 1.319 NM_008887
Phox2a
paired-like homeobox 2a
chr1_-_170362244 1.307 Pbx1
pre B-cell leukemia transcription factor 1
chr6_+_127837728 1.306 Tspan11
tetraspanin 11
chr4_+_129190872 1.299 Marcksl1
MARCKS-like 1
chr3_+_156224757 1.299 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr19_+_4756524 1.293 NM_025717
Rbm4b
RNA binding motif protein 4B
chr5_+_111846284 1.285 Mn1
meningioma 1
chr15_-_96529998 1.268 NM_175121
Slc38a2
solute carrier family 38, member 2
chrX_+_97972559 1.263 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr7_+_37483196 1.261 Tshz3
teashirt zinc finger family member 3
chr7_-_112936063 1.251 NM_001162943
Dchs1
dachsous 1 (Drosophila)
chr9_+_90057930 1.236 Adamts7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr4_+_111087610 1.227 NM_026279
Bend5
BEN domain containing 5
chr13_+_55313130 1.213 Nsd1
nuclear receptor-binding SET-domain protein 1
chr13_-_78337844 1.212 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chrX_-_11657678 1.207 NM_029510
NM_175044
NM_175045
NM_175046
Bcor



BCL6 interacting corepressor



chr6_+_4697305 1.201 NM_001040611
NM_130877
Peg10

paternally expressed 10

chr7_+_30074296 1.194 NM_026731
Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr3_-_122322556 1.183 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr8_+_37157910 1.164 D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr3_+_133899454 1.145 Cxxc4
CXXC finger 4
chr15_+_80004048 1.142 NM_010795
Mgat3
mannoside acetylglucosaminyltransferase 3
chr5_+_21151760 1.131 NM_026034
Armc10
armadillo repeat containing 10
chr4_+_130125682 1.117 NM_025998
Nkain1
Na+/K+ transporting ATPase interacting 1
chr2_-_29701764 1.117 Gm3088
predicted gene 3088
chr7_+_16715637 1.111 NM_148946
Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr3_-_89049088 1.110 NM_001039466
Trim46
tripartite motif-containing 46
chr3_-_156224638 1.102 4930570G19Rik
RIKEN cDNA 4930570G19 gene
chr11_-_62462024 1.100 NM_198861
BC046404
cDNA sequence BC046404
chr4_-_22415277 1.099 NM_008899
Pou3f2
POU domain, class 3, transcription factor 2
chr7_+_16760712 1.088 NM_008627
Meis3
Meis homeobox 3
chrX_+_71550669 1.087 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr5_+_21151630 1.080 Armc10
armadillo repeat containing 10
chr4_-_154010868 1.078 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr4_-_22415444 1.069 Pou3f2
POU domain, class 3, transcription factor 2
chr5_-_138721164 1.067 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr15_-_25343483 1.066 NM_027395
Basp1
brain abundant, membrane attached signal protein 1
chr5_-_132014556 1.066 Auts2
autism susceptibility candidate 2
chr11_-_60988419 1.065 Usp22
ubiquitin specific peptidase 22
chr8_-_107995282 1.059 NM_026481
Tppp3
tubulin polymerization-promoting protein family member 3
chr4_+_118867914 1.057 NM_024462
NM_001038998
Ccdc23

coiled-coil domain containing 23

chr5_-_135028197 1.052 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr10_-_126971614 1.045 NM_183297
Nxph4
neurexophilin 4
chr14_+_15535538 1.041 NM_001033270
Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr4_-_131604821 1.038 NM_001128606
Epb4.1
erythrocyte protein band 4.1
chr14_-_40286109 1.032 Nrg3
neuregulin 3
chr12_-_28027272 1.031 Sox11
SRY-box containing gene 11
chr15_+_98462650 1.031 NM_001044741
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr7_-_52308243 1.030 NM_175022
Prr12
proline rich 12
chr1_-_75313930 1.028 NM_001110831
Dnpep
aspartyl aminopeptidase
chr4_+_41082861 1.027 Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr11_-_105042428 1.004 1700052K11Rik
RIKEN cDNA 1700052K11 gene
chr17_+_73185961 1.003 NM_027166
Ypel5
yippee-like 5 (Drosophila)
chr4_+_48598013 0.999 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_33226980 0.998 NM_175211
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr3_+_130813214 0.994 NM_010703
Lef1
lymphoid enhancer binding factor 1
chr16_-_17928207 0.986 Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chrX_+_71550301 0.981 NM_010273
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr4_+_3866023 0.967 NM_001190323
NM_001190324
NM_001190322
NM_181391
Chchd7



coiled-coil-helix-coiled-coil-helix domain containing 7



chr9_-_37421173 0.955 NM_011449
Spa17
sperm autoantigenic protein 17
chr19_-_5098486 0.955 Cnih2
cornichon homolog 2 (Drosophila)
chr2_-_179839111 0.953 Hrh3
histamine receptor H3
chr8_+_3493117 0.951 NM_080461
Zfp358
zinc finger protein 358
chr1_-_51972771 0.950 Myo1b
myosin IB
chr9_+_120842517 0.948 NM_007614
Ctnnb1
catenin (cadherin associated protein), beta 1
chr1_-_182743632 0.945 NM_008210
H3f3a
H3 histone, family 3A
chr7_+_26067559 0.945 Cic
capicua homolog (Drosophila)
chr17_+_35035395 0.940 NM_147151
Ehmt2
euchromatic histone lysine N-methyltransferase 2
chr8_-_3625251 0.938 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr1_-_173957316 0.936 NM_033509
Vangl2
vang-like 2 (van gogh, Drosophila)
chr1_+_42752608 0.933


chr14_+_77556622 0.926 NM_172813
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr1_-_66864088 0.919 NM_001122738
NM_177645
1110028C15Rik

RIKEN cDNA 1110028C15 gene

chr6_+_125045998 0.918 NM_145979
Chd4
chromodomain helicase DNA binding protein 4
chr3_-_100293092 0.915 NM_001142952
Fam46c
family with sequence similarity 46, member C
chr4_-_55545337 0.915 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr19_-_47538898 0.912 NM_001164717
NM_008018
Sh3pxd2a

SH3 and PX domains 2A

chr4_-_3865501 0.912 NM_019969
Plag1
pleiomorphic adenoma gene 1
chr2_-_91771919 0.910 NM_001012336
Mdk
midkine
chr17_+_15841889 0.910 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr19_-_5424751 0.909 Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr13_+_120217665 0.907 NM_145457
Paip1
polyadenylate binding protein-interacting protein 1
chr2_-_103637096 0.905 NM_001111289
NM_001111290
NM_001111292
Caprin1


cell cycle associated protein 1


chr13_+_104899814 0.904 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr2_-_153270059 0.899 NM_001001986
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr10_+_83903576 0.895


chr19_+_57685498 0.887 NM_181415
Atrnl1
attractin like 1
chr13_-_55589377 0.885 NM_001177371
NM_001177372
NM_019813
Dbn1


drebrin 1


chr17_-_35838974 0.880 NM_001198831
Ddr1
discoidin domain receptor family, member 1
chr13_-_108680257 0.880 NM_145456
Zswim6
zinc finger, SWIM domain containing 6
chr13_+_98011057 0.879 NM_007930
Enc1
ectodermal-neural cortex 1
chr12_-_119539909 0.871 NM_001166385
NM_009239
Sp4

trans-acting transcription factor 4

chr19_+_6363686 0.867 NM_001110791
NM_011750
Sf1

splicing factor 1

chr11_+_80114320 0.867 NM_139228
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr19_-_6996189 0.866 NM_007953
Esrra
estrogen related receptor, alpha
chr12_+_73186837 0.865 Jkamp
JNK1/MAPK8-associated membrane protein
chr1_+_122499031 0.863 NM_010133
En1
engrailed 1
chr12_-_92828018 0.860 NM_031391
Gtf2a1
general transcription factor II A, 1
chr3_-_104024291 0.858 NM_001159354
NM_133853
Magi3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr13_+_42147389 0.854 NM_007772
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr2_-_121097017 0.849 NM_013735
Trp53bp1
transformation related protein 53 binding protein 1
chr6_-_124867962 0.847 NM_026988
Ptms
parathymosin
chr7_-_140315030 0.836 Ctbp2
C-terminal binding protein 2
chr8_+_108384479 0.835 NM_026532
Nutf2
nuclear transport factor 2
chr11_-_11937330 0.829 NM_010345
Grb10
growth factor receptor bound protein 10
chr7_-_81158546 0.826 NM_009181
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr1_-_170362298 0.826 Pbx1
pre B-cell leukemia transcription factor 1
chr1_-_169215189 0.825 Uck2
uridine-cytidine kinase 2
chr11_-_120852554 0.825 Csnk1d
casein kinase 1, delta
chr4_-_41587334 0.823 NM_027147
Enho
energy homeostasis associated
chrX_-_58146562 0.822 NM_009237
Sox3
SRY-box containing gene 3
chr9_-_99776467 0.821 NM_011440
Sox14
SRY-box containing gene 14
chr3_-_101728226 0.820 NM_001039371
Slc22a15
solute carrier family 22 (organic anion/cation transporter), member 15
chr9_-_37240759 0.814 NM_001164767
Robo3
roundabout homolog 3 (Drosophila)
chr19_+_41557475 0.812 Lcor
ligand dependent nuclear receptor corepressor
chr7_+_90015842 0.810 NM_175366
Mex3b
mex3 homolog B (C. elegans)
chr2_-_102291924 0.806 NM_010218
Fjx1
four jointed box 1 (Drosophila)
chr1_+_155587480 0.804 NM_011267
Rgs16
regulator of G-protein signaling 16
chr2_+_18598644 0.803 NM_007552
Bmi1
Bmi1 polycomb ring finger oncogene
chr17_-_31992708 0.799 NM_010831
Sik1
salt inducible kinase 1
chr9_-_36954842 0.796 NM_001029838
Pknox2
Pbx/knotted 1 homeobox 2
chr2_-_30329737 0.796 Ier5l
immediate early response 5-like
chr1_-_157264398 0.795 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_+_98656807 0.795 Msl1
male-specific lethal 1 homolog (Drosophila)
chr10_-_117147722 0.794 Mdm2
transformed mouse 3T3 cell double minute 2
chr1_-_153937364 0.794 NM_197990
LOC545371
1700025G04Rik
hypothetical protein LOC545371
RIKEN cDNA 1700025G04 gene
chr10_-_127058163 0.789 Lrp1
low density lipoprotein receptor-related protein 1
chr15_-_85412250 0.787 NM_009528
Wnt7b
wingless-related MMTV integration site 7B
chr1_-_84281018 0.783 Pid1
phosphotyrosine interaction domain containing 1
chr3_+_121129396 0.783 NM_028044
Cnn3
calponin 3, acidic
chr9_-_45714409 0.778 Rnf214
ring finger protein 214
chr11_+_61890494 0.777 NM_001029936
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_+_106584074 0.776 NM_023672
NM_198438
Ssbp3

single-stranded DNA binding protein 3

chr12_-_119539840 0.773 Sp4
trans-acting transcription factor 4
chr1_-_140743779 0.772 Lhx9
LIM homeobox protein 9
chr4_+_130125551 0.766 Nkain1
Na+/K+ transporting ATPase interacting 1
chr15_-_38008565 0.765 NM_001081359
NM_001112721
Ubr5

ubiquitin protein ligase E3 component n-recognin 5

chr11_+_3190334 0.764 NM_019574
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_174242554 0.761 Igsf8
immunoglobulin superfamily, member 8
chr10_+_36226612 0.758 NM_001081208
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr11_-_23397927 0.758 NM_172391
Ahsa2
AHA1, activator of heat shock protein ATPase homolog 2 (yeast)
chr5_+_145016060 0.756 NM_018772
Bri3
brain protein I3
chr11_-_97560852 0.753 Pcgf2
polycomb group ring finger 2
chr5_-_133019167 0.750 Auts2
autism susceptibility candidate 2
chr8_+_130882920 0.749 NM_008737
Nrp1
neuropilin 1
chrX_+_71550562 0.748 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr2_+_19367264 0.747 NM_018809
Ptf1a
pancreas specific transcription factor, 1a
chr2_+_154617083 0.743 Raly
a
hnRNP-associated with lethal yellow
nonagouti

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.61 7.14e-04 GO:0051252 regulation of RNA metabolic process
2.48 7.27e-04 GO:0010468 regulation of gene expression
2.80 9.36e-04 GO:0030154 cell differentiation
2.57 9.89e-04 GO:0048731 system development
4.16 1.07e-03 GO:0022008 neurogenesis
3.50 1.11e-03 GO:0007399 nervous system development
2.72 1.58e-03 GO:0048869 cellular developmental process
2.57 1.65e-03 GO:0006355 regulation of transcription, DNA-dependent
2.45 2.49e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
4.14 2.52e-03 GO:0048699 generation of neurons
2.39 2.54e-03 GO:0048856 anatomical structure development
2.39 3.97e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.24 5.57e-03 GO:0007275 multicellular organismal development
2.75 6.37e-03 GO:0006351 transcription, DNA-dependent
2.74 6.55e-03 GO:0032774 RNA biosynthetic process
2.72 7.38e-03 GO:0048513 organ development
3.52 8.01e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
14.72 9.24e-03 GO:0051147 regulation of muscle cell differentiation
2.27 9.83e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.26 1.11e-02 GO:0031326 regulation of cellular biosynthetic process
2.25 1.19e-02 GO:0051171 regulation of nitrogen compound metabolic process
2.23 1.39e-02 GO:0009889 regulation of biosynthetic process
42.96 1.75e-02 GO:0030325 adrenal gland development
2.34 1.96e-02 GO:0016070 RNA metabolic process
40.28 2.14e-02 GO:0007416 synapse assembly
2.06 2.77e-02 GO:0032502 developmental process
35.81 3.10e-02 GO:0043576 regulation of respiratory gaseous exchange
4.98 3.27e-02 GO:0060284 regulation of cell development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment p-value GO term description
4.66 1.46e-06 GO:0030528 transcription regulator activity
5.44 2.80e-06 GO:0043565 sequence-specific DNA binding
2.92 1.76e-04 GO:0003677 DNA binding
2.45 3.52e-04 GO:0003676 nucleic acid binding
3.14 6.07e-04 GO:0008270 zinc ion binding
7.17 1.43e-03 GO:0000988 protein binding transcription factor activity
3.82 2.86e-03 GO:0001071 nucleic acid binding transcription factor activity
3.82 2.86e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
11.56 6.62e-03 GO:0003714 transcription corepressor activity
2.62 7.47e-03 GO:0046914 transition metal ion binding
5.50 9.37e-03 GO:0016564 transcription repressor activity
6.38 1.04e-02 GO:0003712 transcription cofactor activity
6.35 1.07e-02 GO:0000989 transcription factor binding transcription factor activity