Motif ID: PITX1..3.p2

Z-value: 1.941

Transcription factors associated with PITX1..3.p2:

NameEntrezDescription
Pitx1 18740 paired-like homeodomain transcription factor 1
Pitx2 18741 paired-like homeodomain transcription factor 2
Pitx3 18742 paired-like homeodomain transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Pitx2chr3_+_1289028220.212.2e-01Click!


Activity profile for motif PITX1..3.p2.

activity profile for motif PITX1..3.p2


Sorted Z-values histogram for motif PITX1..3.p2

Sorted Z-values for motif PITX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Description
chr6_+_34304098 9.866 NM_008012
Akr1b8
aldo-keto reductase family 1, member B8
chr4_-_116855158 9.583 NM_134471
Kif2c
kinesin family member 2C
chr7_-_150646883 9.374 NM_001161624
NM_009876
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr6_+_55967487 9.205 Gsbs
G substrate
chr6_-_88848650 7.076 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr14_+_67254087 6.828 NM_013461
Adra1a
adrenergic receptor, alpha 1a
chr11_+_101303558 6.681 NM_011289
Rpl27
ribosomal protein L27
chr11_-_40508405 6.621 Mat2b
methionine adenosyltransferase II, beta
chr4_-_33010429 6.414 NM_001012450
NM_080471
Ankrd6

ankyrin repeat domain 6

chr9_-_70269326 6.035 NM_007630
Ccnb2
cyclin B2
chr1_+_173155184 5.909 NM_013474
Apoa2
apolipoprotein A-II
chr16_-_4719058 5.745 NM_026393
Nmral1
NmrA-like family domain containing 1
chr2_+_79547936 5.404 NM_172420
Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_44966657 5.207 NM_001177394
Gm13476
predicted gene 13476
chr4_+_41082861 4.755 Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr8_-_74035629 4.589 Plvap
plasmalemma vesicle associated protein
chr1_+_94803538 4.374 NM_175118
Dusp28
dual specificity phosphatase 28
chr7_-_20277986 4.240 NM_001110009
Apoc1
apolipoprotein C-I
chr8_-_74035667 4.199 NM_032398
Plvap
plasmalemma vesicle associated protein
chr8_-_106966899 4.118 NM_001013380
Dync1li2
dynein, cytoplasmic 1 light intermediate chain 2
chr12_+_52449216 4.116 NM_001015099
NM_001167963
NM_001167964
G2e3


G2/M-phase specific E3 ubiquitin ligase


chr6_+_83299439 4.114 NM_175277
Bola3
bolA-like 3 (E. coli)
chr4_+_88783273 4.099 NM_024433
Mtap
methylthioadenosine phosphorylase
chr11_-_106860750 4.078 Kpna2
karyopherin (importin) alpha 2
chr14_-_21000972 3.996 NM_021542
Kcnk5
potassium channel, subfamily K, member 5
chr18_-_74367400 3.967 NM_001164355
NM_025581
Ska1

spindle and kinetochore associated complex subunit 1

chr13_-_22133203 3.950 NM_175656
Hist1h4i
histone cluster 1, H4i
chr10_+_97028409 3.949 Lum
lumican
chr5_-_138052555 3.909 NM_008788
Pcolce
procollagen C-endopeptidase enhancer protein
chr2_-_126959605 3.877 NM_144818
Ncaph
non-SMC condensin I complex, subunit H
chr5_+_135058559 3.819 NM_020022
Rfc2
replication factor C (activator 1) 2
chr2_-_44968508 3.688 Zeb2
zinc finger E-box binding homeobox 2
chr11_-_68821930 3.666 NM_001159519
Pfas
phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
chr18_+_80403500 3.614 NM_001038608
NM_025299
Txnl4a

thioredoxin-like 4A

chr12_-_29320713 3.554 Rps7
ribosomal protein S7
chr9_-_96378951 3.535 NM_011279
Rnf7
ring finger protein 7
chr16_+_38562924 3.481 NM_026407
Tmem39a
transmembrane protein 39a
chr14_-_48037815 3.463 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_-_70269246 3.443 Ccnb2
cyclin B2
chr15_+_80778910 3.406 NM_009634
Adsl
adenylosuccinate lyase
chr16_+_55966387 3.369 NM_024218
Rpl24
ribosomal protein L24
chr10_-_92185071 3.353 NM_008682
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr4_-_148511650 3.331 NM_027263
Apitd1
apoptosis-inducing, TAF9-like domain 1
chr11_-_86071041 3.327 NM_027421
Ints2
integrator complex subunit 2
chr15_-_82074765 3.295 NM_001080158
Cenpm
centromere protein M
chr6_-_127075853 3.265 Ccnd2
cyclin D2
chr11_-_78564918 3.264 NM_197989
Fam58b
family with sequence similarity 58, member B
chr1_+_88024759 3.262 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr17_-_28759356 3.262 NM_016795
Srpk1
serine/arginine-rich protein specific kinase 1
chr9_+_103207488 3.248 NM_176979
Topbp1
topoisomerase (DNA) II binding protein 1
chr8_+_18595130 3.209 NM_173189
Mcph1
microcephaly, primary autosomal recessive 1
chr4_+_100449274 3.168 NM_198037
Cachd1
cache domain containing 1
chr16_+_55966458 3.158 Rpl24
ribosomal protein L24
chr12_-_29320801 3.096 NM_011300
Rps7
ribosomal protein S7
chr4_+_153385839 3.095 NM_201226
Lrrc47
leucine rich repeat containing 47
chr8_-_11635688 3.044 Ankrd10
ankyrin repeat domain 10
chr5_-_134932407 3.034 NM_001081462
NM_001081463
NM_001081464
NM_001081466
NM_001081467
NM_001081468
NM_001081469
NM_001081470
NM_020331
Gtf2ird1








general transcription factor II I repeat domain-containing 1








chr5_-_139936486 3.029 NM_028469
3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr5_+_138220097 3.005 NM_027242
2010007H12Rik
RIKEN cDNA 2010007H12 gene
chr7_-_125728199 2.985 NM_172476
Tmc7
transmembrane channel-like gene family 7
chr10_-_62254998 2.974 Ccar1
cell division cycle and apoptosis regulator 1
chr10_+_128184908 2.952 NM_030100
Wibg
within bgcn homolog (Drosophila)
chr4_-_86257921 2.931 NM_173400
Haus6
HAUS augmin-like complex, subunit 6
chr11_+_96891242 2.926 NM_146027
Scrn2
secernin 2
chr3_-_153575890 2.893 NM_001163478
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr11_+_114529837 2.883 NM_001048057
NM_023372
Rpl38

ribosomal protein L38

chr3_-_86978431 2.883 NM_001170985
NM_130867
Kirrel

kin of IRRE like (Drosophila)

chr9_+_118415358 2.864 NM_018748
Golga4
golgi autoantigen, golgin subfamily a, 4
chr3_-_96001504 2.858 NM_026975
Bola1
bolA-like 1 (E. coli)
chr11_+_3863948 2.858 NM_022889
Pes1
pescadillo homolog 1, containing BRCT domain (zebrafish)
chr1_+_87690003 2.845 NM_133781
Cab39
calcium binding protein 39
chr7_+_135047561 2.834 NM_009739
Bckdk
branched chain ketoacid dehydrogenase kinase
chr3_-_146184337 2.832 NM_027332
NM_027371
Rpf1

ribosome production factor 1 homolog (S. cerevisiae)

chr5_-_123632567 2.805 NM_008277
Hpd
4-hydroxyphenylpyruvic acid dioxygenase
chrX_-_137491205 2.793 NM_001164177
NM_016883
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr8_+_116657473 2.731 NM_024437
NM_024446
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr2_+_157563136 2.680 NM_025680
Ctnnbl1
catenin, beta like 1
chr10_-_43260744 2.662 NM_026411
1700021F05Rik
RIKEN cDNA 1700021F05 gene
chr10_+_20067606 2.629 NM_027930
Fam54a
family with sequence similarity 54, member A
chr7_+_17477134 2.594 NM_010320
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr8_+_73197262 2.584 Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_94914936 2.548 NM_009336
Vps72
vacuolar protein sorting 72 (yeast)
chr5_-_137462712 2.545 Znhit1
zinc finger, HIT domain containing 1
chr8_+_80073336 2.533 Prmt10
protein arginine methyltransferase 10 (putative)
chr10_-_88289526 2.532 NM_175158
Utp20
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr17_+_71965554 2.515 NM_175639
Wdr43
WD repeat domain 43
chr1_-_36300951 2.511 Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_-_28438708 2.510 Gtf3c5
general transcription factor IIIC, polypeptide 5
chr10_-_62254978 2.499 Ccar1
cell division cycle and apoptosis regulator 1
chr5_+_138558132 2.482 NM_001044703
NM_001044704
NM_001044705
NM_011757
Zscan21



zinc finger and SCAN domain containing 21



chr9_+_110558996 2.478 NM_028312
Ccdc12
coiled-coil domain containing 12
chr10_+_42221829 2.476 NM_017472
Snx3
sorting nexin 3
chr17_+_27693518 2.456 NM_001166476
NM_001166477
NM_001025427
NM_001039356
NM_001166535
NM_001166536
NM_001166539
NM_001166540
NM_001166541
NM_001166542
NM_001166543
NM_001166544
NM_001166545
NM_001166546
NM_001166537
NM_016660
Hmga1-rs1

Hmga1













high mobility group AT-hook I, related sequence 1

high mobility group AT-hook 1













chr5_-_92738981 2.453 Sdad1
SDA1 domain containing 1
chr15_-_82075137 2.445 NM_025639
NM_178269
Cenpm

centromere protein M

chr8_-_123112974 2.439 NM_178856
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr6_-_120307360 2.429 NM_026028
Ccdc77
coiled-coil domain containing 77
chr2_+_174241304 2.418 NM_020580
Th1l
TH1-like homolog (Drosophila)
chr1_-_129998984 2.418 NM_027678
Zranb3
zinc finger, RAN-binding domain containing 3
chr4_+_41082993 2.415 NM_026275
Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr14_-_48037874 2.412 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr2_+_165818136 2.410 NM_008679
Ncoa3
nuclear receptor coactivator 3
chr5_+_110660011 2.395 NM_027922
Ankle2
ankyrin repeat and LEM domain containing 2
chr1_+_157887985 2.395 NM_001160181
NM_022329
Tor1aip2

torsin A interacting protein 2

chr8_-_114516147 2.384 NM_013925
Adat1
adenosine deaminase, tRNA-specific 1
chrX_+_137909951 2.383 NM_001163155
NM_007736
Col4a5

collagen, type IV, alpha 5

chr6_+_113102884 2.375 Setd5
SET domain containing 5
chr9_+_72887524 2.371 2310009A05Rik
5031420N21Rik
RIKEN cDNA 2310009A05 gene
RIKEN cDNA 5031420N21 gene
chr11_+_32105414 2.364 NM_030093
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr19_+_6061181 2.362 NM_013859
Znhit2-ps
zinc finger, HIT domain containing 2, pseudogene
chr6_-_128476708 2.330 NM_007376
Pzp
pregnancy zone protein
chr2_+_128926721 2.319 NM_009086
Polr1b
polymerase (RNA) I polypeptide B
chr5_-_113709569 2.313 Sgsm1
small G protein signaling modulator 1
chr2_-_29949088 2.282 NM_001037762
NM_025428
Zdhhc12

zinc finger, DHHC domain containing 12

chr7_-_20355818 2.274 Bcam
basal cell adhesion molecule
chr9_+_54798578 2.271 NM_011966
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr16_-_56037836 2.265 NM_029092
Rg9mtd1
RNA (guanine-9-) methyltransferase domain containing 1
chr5_-_139936448 2.256 3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr2_+_91386476 2.247 NM_001165989
NM_029437
Ckap5

cytoskeleton associated protein 5

chr6_-_29559792 2.242 Tnpo3
transportin 3
chr18_+_31963757 2.235 Wdr33
WD repeat domain 33
chr18_+_80403581 2.167 NM_178604
Txnl4a
thioredoxin-like 4A
chr18_-_24688688 2.148 NM_144861
Rprd1a
regulation of nuclear pre-mRNA domain containing 1A
chr18_+_80403577 2.147 Txnl4a
thioredoxin-like 4A
chr12_-_70260137 2.141 NM_009093
Rps29
ribosomal protein S29
chr10_-_67741461 2.116 NM_023598
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr1_-_153347884 2.112 NM_011277
Rnf2
ring finger protein 2
chr10_+_7387285 2.099 NM_145706
Nup43
nucleoporin 43
chr15_-_102181072 2.091 NM_153416
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr5_-_86601756 2.070 NM_172712
Uba6
ubiquitin-like modifier activating enzyme 6
chr5_-_138596915 2.069 NM_019747
Zfp113
zinc finger protein 113
chr2_-_30657226 2.026 NM_198000
1700001O22Rik
RIKEN cDNA 1700001O22 gene
chr4_-_12015073 2.025 NM_177861
Tmem67
transmembrane protein 67
chr2_-_130455670 2.023 NM_080562
Ubox5
Fastkd5
U box domain containing 5
FAST kinase domains 5
chr9_-_64188945 2.013 NM_001001295
Dis3l
DIS3 mitotic control homolog (S. cerevisiae)-like
chr10_-_70700764 2.003 NM_009360
Tfam
transcription factor A, mitochondrial
chr8_-_11635748 2.000 NM_001167967
NM_133971
Ankrd10

ankyrin repeat domain 10

chr11_-_106860803 1.992 NM_010655
Kpna2
karyopherin (importin) alpha 2
chr1_-_141273617 1.949 NM_133239
Crb1
crumbs homolog 1 (Drosophila)
chr18_+_80403593 1.947 NM_001042408
Txnl4a
thioredoxin-like 4A
chr11_+_80196766 1.944 NM_001130169
NM_001130170
NM_001130171
NM_011751
Zfp207



zinc finger protein 207



chr6_-_71773747 1.932 NM_025430
Mrpl35
mitochondrial ribosomal protein L35
chr5_+_108329554 1.930 NM_016980
Rpl5
ribosomal protein L5
chr10_-_90612412 1.924 Tmpo
thymopoietin
chr9_+_15110657 1.914 NM_027261
NM_029248
Taf1d

TATA box binding protein (Tbp)-associated factor, RNA polymerase I, D

chr9_-_20954341 1.912 NM_016742
Cdc37
cell division cycle 37 homolog (S. cerevisiae)
chr11_+_62271961 1.904 NM_001039536
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr10_+_57960671 1.902 NM_001162956
Ccdc138
coiled-coil domain containing 138
chr14_-_31832165 1.895 Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr13_-_54570167 1.889 NM_028597
Thoc3
THO complex 3
chr7_-_71518926 1.889 NM_177893
Fan1
FANCD2/FANCI-associated nuclease 1
chr1_-_121545442 1.875 NM_001113416
NM_145506
Epb4.1l5

erythrocyte protein band 4.1-like 5

chr14_+_56364564 1.864 2610027L16Rik
RIKEN cDNA 2610027L16 gene
chr2_-_44968728 1.863 NM_015753
Zeb2
zinc finger E-box binding homeobox 2
chr8_+_86239131 1.851 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr15_+_72920827 1.847 NM_053068
Chrac1
chromatin accessibility complex 1
chr15_+_102313591 1.815 Pcbp2
poly(rC) binding protein 2
chr8_+_87550720 1.808 NM_026760
2310036O22Rik
RIKEN cDNA 2310036O22 gene
chr15_+_8059306 1.800 NM_133227
Nup155
nucleoporin 155
chr14_+_27852148 1.799 NM_134437
Il17rd
interleukin 17 receptor D
chr15_-_98748371 1.785 NM_029098
Lmbr1l
limb region 1 like
chr2_+_127034130 1.783 NM_177214
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr15_-_99200868 1.775 NM_011711
Fmnl3
formin-like 3
chr2_-_28438389 1.772 Gtf3c5
general transcription factor IIIC, polypeptide 5
chr9_+_99476204 1.760 NM_031403
Dbr1
debranching enzyme homolog 1 (S. cerevisiae)
chr11_+_32646291 1.748 Fbxw11
F-box and WD-40 domain protein 11
chrX_+_93651684 1.742 NM_001159627
NM_181273
Heph

hephaestin

chr19_-_47611490 1.709 NM_175360
Obfc1
oligonucleotide/oligosaccharide-binding fold containing 1
chr2_+_164388211 1.707 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chr14_-_79790474 1.680 NM_025832
Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr10_+_84085020 1.675 Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chr9_+_69245718 1.674 NM_145618
Narg2
NMDA receptor-regulated gene 2
chr11_-_121090513 1.668 NM_144832
BC017643
cDNA sequence BC017643
chr10_+_62409776 1.664 NM_177372
Dna2
DNA replication helicase 2 homolog (yeast)
chr5_-_130731280 1.639 NM_023248
Sbds
Shwachman-Bodian-Diamond syndrome homolog (human)
chr15_+_76709688 1.625 NM_145916
Zfp7
zinc finger protein 7
chr4_+_33397279 1.610 NM_011884
Rngtt
RNA guanylyltransferase and 5'-phosphatase
chr7_+_29225955 1.608 NM_001039192
Gmfg
glia maturation factor, gamma
chr11_+_75570397 1.603 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr9_-_46043339 1.599 NM_023114
Apoc3
apolipoprotein C-III
chr11_+_20125239 1.598 Rab1
RAB1, member RAS oncogene family
chr19_+_36158191 1.587 NM_019428
Rpp30
ribonuclease P/MRP 30 subunit (human)
chr6_-_49195555 1.587 Tra2a
transformer 2 alpha homolog (Drosophila)
chr12_+_85291629 1.573 2410016O06Rik
RIKEN cDNA 2410016O06 gene
chr19_-_38893670 1.570 NM_021315
Noc3l
nucleolar complex associated 3 homolog (S. cerevisiae)
chr19_-_41970627 1.560 NM_199447
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr11_-_5442157 1.556 NM_134033
Ccdc117
coiled-coil domain containing 117
chr8_-_3467624 1.554 NM_026951
Pex11c
peroxisomal biogenesis factor 11 gamma
chr3_+_89070473 1.553 NM_026767
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr9_+_37015872 1.541 NM_025464
Tmem218
transmembrane protein 218
chr7_+_25378887 1.529 Ethe1
ethylmalonic encephalopathy 1
chr7_-_52409783 1.498 NM_145954
Aldh16a1
aldehyde dehydrogenase 16 family, member A1
chr17_+_35998262 1.495 NM_134122
Nrm
nurim (nuclear envelope membrane protein)
chr17_+_49567718 1.495 Mocs1
molybdenum cofactor synthesis 1
chr9_-_61918412 1.489 NM_033320
Glce
glucuronyl C5-epimerase
chr9_-_107888185 1.484 6230427J02Rik
RIKEN cDNA 6230427J02 gene
chrX_+_34142137 1.476


chr16_+_35770431 1.475 NM_175111
Hspbap1
Hspb associated protein 1
chr7_+_27814096 1.472 NM_133657
Cyp2a12
cytochrome P450, family 2, subfamily a, polypeptide 12
chr18_-_74367362 1.469 Ska1
spindle and kinetochore associated complex subunit 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.97 7.36e-13 GO:0044260 cellular macromolecule metabolic process
1.84 5.13e-11 GO:0043170 macromolecule metabolic process
4.35 6.98e-09 GO:0006396 RNA processing
1.63 2.14e-08 GO:0044237 cellular metabolic process
1.61 4.80e-08 GO:0044238 primary metabolic process
2.12 2.86e-07 GO:0010467 gene expression
1.50 1.48e-06 GO:0008152 metabolic process
2.02 2.55e-06 GO:0090304 nucleic acid metabolic process
2.12 7.37e-06 GO:0044267 cellular protein metabolic process
1.87 1.27e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.80 2.15e-05 GO:0034641 cellular nitrogen compound metabolic process
5.35 2.38e-05 GO:0034660 ncRNA metabolic process
2.04 2.55e-05 GO:0016070 RNA metabolic process
1.77 3.34e-05 GO:0006807 nitrogen compound metabolic process
3.35 8.55e-05 GO:0022402 cell cycle process
6.69 2.60e-04 GO:0042254 ribosome biogenesis
5.52 2.85e-04 GO:0034470 ncRNA processing
1.87 3.14e-04 GO:0019538 protein metabolic process
4.40 4.01e-04 GO:0006412 translation
2.80 4.10e-04 GO:0007049 cell cycle
1.93 8.14e-04 GO:0071841 cellular component organization or biogenesis at cellular level
7.43 9.97e-04 GO:0016072 rRNA metabolic process
1.88 1.03e-03 GO:0009059 macromolecule biosynthetic process
4.29 1.21e-03 GO:0008380 RNA splicing
40.77 1.33e-03 GO:0032372 negative regulation of sterol transport
40.77 1.33e-03 GO:0032375 negative regulation of cholesterol transport
3.65 1.43e-03 GO:0000278 mitotic cell cycle
1.86 1.71e-03 GO:0034645 cellular macromolecule biosynthetic process
4.78 3.82e-03 GO:0071843 cellular component biogenesis at cellular level
6.91 6.49e-03 GO:0006364 rRNA processing
53.51 1.12e-02 GO:0010915 regulation of very-low-density lipoprotein particle clearance
53.51 1.12e-02 GO:0010916 negative regulation of very-low-density lipoprotein particle clearance
53.51 1.12e-02 GO:0048261 negative regulation of receptor-mediated endocytosis
1.68 1.13e-02 GO:0071840 cellular component organization or biogenesis
4.66 1.19e-02 GO:0022613 ribonucleoprotein complex biogenesis
25.95 1.20e-02 GO:0033700 phospholipid efflux
25.95 1.20e-02 GO:0042273 ribosomal large subunit biogenesis
2.07 1.27e-02 GO:0006996 organelle organization
1.65 1.82e-02 GO:0044249 cellular biosynthetic process
2.28 2.42e-02 GO:0044085 cellular component biogenesis
1.63 2.50e-02 GO:0009058 biosynthetic process
6.42 3.67e-02 GO:0006414 translational elongation
1.79 3.76e-02 GO:0071842 cellular component organization at cellular level
19.03 4.74e-02 GO:0032369 negative regulation of lipid transport

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.90 5.21e-13 GO:0005634 nucleus
1.43 1.51e-11 GO:0044424 intracellular part
1.41 3.11e-11 GO:0005622 intracellular
1.48 1.50e-10 GO:0043229 intracellular organelle
1.54 1.52e-10 GO:0043231 intracellular membrane-bounded organelle
1.53 1.86e-10 GO:0043227 membrane-bounded organelle
1.48 2.03e-10 GO:0043226 organelle
1.98 1.32e-08 GO:0032991 macromolecular complex
2.45 2.17e-08 GO:0044428 nuclear part
4.02 3.49e-07 GO:0030529 ribonucleoprotein complex
2.05 1.42e-06 GO:0043228 non-membrane-bounded organelle
2.05 1.42e-06 GO:0043232 intracellular non-membrane-bounded organelle
2.23 7.30e-06 GO:0031974 membrane-enclosed lumen
1.69 1.02e-05 GO:0044446 intracellular organelle part
2.20 2.43e-05 GO:0070013 intracellular organelle lumen
2.19 2.57e-05 GO:0043233 organelle lumen
1.66 2.58e-05 GO:0044422 organelle part
2.22 1.17e-04 GO:0031981 nuclear lumen
3.71 1.91e-04 GO:0005730 nucleolus
3.22 8.67e-04 GO:0005694 chromosome
4.65 4.80e-03 GO:0005840 ribosome
20.39 5.99e-03 GO:0030684 preribosome
2.96 1.26e-02 GO:0044427 chromosomal part
30.58 1.62e-02 GO:0034366 spherical high-density lipoprotein particle
15.86 1.75e-02 GO:0034361 very-low-density lipoprotein particle
15.86 1.75e-02 GO:0034385 triglyceride-rich lipoprotein particle
2.58 1.95e-02 GO:0015630 microtubule cytoskeleton
12.97 4.01e-02 GO:0034364 high-density lipoprotein particle

Gene overrepresentation in function category:

enrichment p-value GO term description
1.85 1.34e-04 GO:0003676 nucleic acid binding
2.70 1.00e-03 GO:0003723 RNA binding
25.95 2.53e-03 GO:0055102 lipase inhibitor activity
3.25 2.86e-03 GO:0016874 ligase activity
1.24 4.82e-03 GO:0005488 binding
3.53 2.00e-02 GO:0004857 enzyme inhibitor activity