Motif ID: POU2F1..3.p2

Z-value: 1.605

Transcription factors associated with POU2F1..3.p2:

NameEntrezDescription
Pou2f1 18986 POU domain, class 2, transcription factor 1
Pou2f2 18987 POU domain, class 2, transcription factor 2
Pou2f3 18988 POU domain, class 2, transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Pou2f1chr1_-_1679327350.677.6e-06Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr1_-_42749940 16.776 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr13_+_23838602 16.704 NM_175664
Hist1h2bb
histone cluster 1, H2bb
chr13_+_23776066 15.334 NM_023422
Hist1h2bc
histone cluster 1, H2bc
chr13_-_23775827 14.722 NM_178189
Hist1h2ac
histone cluster 1, H2ac
chr2_+_25036276 13.546 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr13_+_22135065 10.215 NM_178198
Hist1h2bj
histone cluster 1, H2bj
chr13_-_23635220 8.647 NM_178197
Hist1h2bh
histone cluster 1, H2bh
chr14_+_67853446 8.409 Ebf2
early B-cell factor 2
chr1_+_6720153 8.314 St18
suppression of tumorigenicity 18
chr13_+_21813912 8.301 NM_178200
Hist1h2bm
histone cluster 1, H2bm
chr13_+_21879356 8.184 NM_178202
Hist1h2bp
histone cluster 1, H2bp
chrX_+_97972559 7.955 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr8_+_71404491 7.900 Lpl
lipoprotein lipase
chr13_-_23677831 7.088 Hist1h2be
histone cluster 1, H2be
chr13_+_22127689 7.009 NM_175665
Hist1h2bk
histone cluster 1, H2bk
chr11_+_58768179 6.914 NM_178218
Hist3h2a
histone cluster 3, H2a
chr13_+_23663264 6.794 NM_178196
Hist1h2bg
histone cluster 1, H2bg
chr13_+_23842956 6.332 NM_175660
Hist1h2ab
histone cluster 1, H2ab
chr11_+_61890494 6.264 NM_001029936
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr13_-_22127419 6.121 NM_175659
Hist1h2ah
histone cluster 1, H2ah
chr3_+_96073622 6.037 NM_175666
Hist2h2bb
histone cluster 2, H2bb
chr14_-_68333427 6.022 Cdca2
cell division cycle associated 2
chr13_-_23663006 6.022 NM_178187
Hist1h2ae
histone cluster 1, H2ae
chr7_+_52273317 5.927 NM_009101
Rras
Harvey rat sarcoma oncogene, subgroup R
chr13_-_22134795 5.776 NM_178186
Hist1h2ag
Hist1h2ai
histone cluster 1, H2ag
histone cluster 1, H2ai
chr4_-_129374039 5.369 NM_199305
Tmem39b
transmembrane protein 39b
chr2_+_51893618 5.277 NM_009398
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr1_-_93309713 5.266 NM_019479
Hes6
hairy and enhancer of split 6 (Drosophila)
chr12_-_35213738 5.167 NM_024124
Hdac9
histone deacetylase 9
chr14_-_68333397 5.151 Cdca2
cell division cycle associated 2
chr13_+_23666249 5.087 NM_178188
Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr19_+_9016335 4.870 NM_011842
Mta2
metastasis-associated gene family, member 2
chr2_+_109757803 4.648 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr17_+_27693518 4.603 NM_001166476
NM_001166477
NM_001025427
NM_001039356
NM_001166535
NM_001166536
NM_001166539
NM_001166540
NM_001166541
NM_001166542
NM_001166543
NM_001166544
NM_001166545
NM_001166546
NM_001166537
NM_016660
Hmga1-rs1

Hmga1













high mobility group AT-hook I, related sequence 1

high mobility group AT-hook 1













chr1_+_6720087 4.518 NM_173868
St18
suppression of tumorigenicity 18
chr13_-_23666058 4.485 NM_178195
Hist1h2bf
histone cluster 1, H2bf
chr11_-_86621074 4.376 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr5_+_138070341 4.153 NM_001168652
NM_146164
Lrch4-sap25
Lrch4

Lrch4-Sap25 gene
leucine-rich repeats and calponin homology (CH) domain containing 4

chr3_-_96024766 4.074 NM_175662
Hist2h2ac
histone cluster 2, H2ac
chr8_-_49075838 4.027 Wwc2
WW, C2 and coiled-coil domain containing 2
chr8_-_49075724 3.982 Wwc2
WW, C2 and coiled-coil domain containing 2
chr2_+_72314235 3.949 NM_025866
Cdca7
cell division cycle associated 7
chr5_-_21207184 3.934 Napepld
N-acyl phosphatidylethanolamine phospholipase D
chr11_+_98821784 3.859 NM_001176528
Rara
retinoic acid receptor, alpha
chr7_+_106614513 3.835 NM_028145
Klhl35
kelch-like 35 (Drosophila)
chr11_+_58762401 3.827 NM_030082
Hist3h2ba
histone cluster 3, H2ba
chr2_+_155207581 3.635 NM_178111
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr7_-_52252911 3.514 NM_029410
Bcl2l12
BCL2-like 12 (proline rich)
chr4_-_33010429 3.503 NM_001012450
NM_080471
Ankrd6

ankyrin repeat domain 6

chr11_-_30098163 3.449 NM_009260
Spnb2
spectrin beta 2
chr9_-_71743854 3.430 Tcf12
transcription factor 12
chr11_-_102046532 3.422 NM_172947
Lsm12
LSM12 homolog (S. cerevisiae)
chr10_+_97028409 3.378 Lum
lumican
chr19_+_9016466 3.334 Mta2
metastasis-associated gene family, member 2
chr11_-_63735652 3.329 NM_018805
Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr11_+_88107544 3.164 NM_028859
1700106J16Rik
RIKEN cDNA 1700106J16 gene
chr6_-_92431385 3.126 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr7_-_29157512 3.126 NM_001083912
NM_138752
Plekhg2

pleckstrin homology domain containing, family G (with RhoGef domain) member 2

chr7_+_148381017 3.113 NM_153777
Lrrc56
leucine rich repeat containing 56
chr10_-_13043959 2.975 NM_001033257
NM_001195096
Phactr2

phosphatase and actin regulator 2

chr17_+_29627697 2.973 Pim1
proviral integration site 1
chr3_+_133902563 2.954 Cxxc4
CXXC finger 4
chr10_+_62409776 2.916 NM_177372
Dna2
DNA replication helicase 2 homolog (yeast)
chrX_+_106290703 2.878 NM_019989
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr8_+_123059756 2.865 NM_001145897
Gse1
genetic suppressor element 1
chr1_-_165243608 2.752 Prrx1
paired related homeobox 1
chr10_-_79371636 2.668 NM_001163276
NM_198107
Med16

mediator complex subunit 16

chr10_-_90545406 2.646 Apaf1
apoptotic peptidase activating factor 1
chr8_+_71404452 2.584 NM_008509
Lpl
lipoprotein lipase
chr15_+_57526212 2.580 NM_199449
Zhx2
zinc fingers and homeoboxes 2
chr17_-_15512773 2.484 NM_007865
Dll1
delta-like 1 (Drosophila)
chr7_+_132695758 2.478 NM_001008700
Il4ra
interleukin 4 receptor, alpha
chr7_+_17460697 2.466 Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr13_+_41012969 2.421 NM_133219
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr13_-_54789548 2.405 NM_001146027
Rnf44
ring finger protein 44
chr5_+_73305509 2.345 NM_001113423
NM_153567
Slain2

SLAIN motif family, member 2

chr10_+_128143313 2.343 NM_021882
Pmel
premelanosome protein
chr11_-_86621130 2.267 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_+_154335029 2.145 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr13_+_72766425 2.132 NM_010574
Irx2
Iroquois related homeobox 2 (Drosophila)
chr10_-_8605668 2.107 NM_175155
Sash1
SAM and SH3 domain containing 1
chr13_-_54789148 2.074 NM_001146025
NM_001146026
NM_134064
Rnf44


ring finger protein 44


chr11_+_57985140 2.073 NM_175001
Mrpl22
mitochondrial ribosomal protein L22
chr12_-_80397239 2.041 NM_001008550
Zfyve26
zinc finger, FYVE domain containing 26
chr10_+_18189773 2.034 NM_001163592
Nhsl1
NHS-like 1
chr15_-_82979687 2.029 NM_178627
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr1_+_45368568 1.991 Col3a1
collagen, type III, alpha 1
chr1_-_165243777 1.979 NM_001025570
NM_011127
NM_175686
Prrx1


paired related homeobox 1


chr1_+_36528441 1.954 NM_033570
Cnnm4
cyclin M4
chr3_+_96023838 1.924 NM_178213
Hist2h2ab
histone cluster 2, H2ab
chr5_+_137384005 1.923 NM_026073
Rabl5
RAB, member of RAS oncogene family-like 5
chr5_-_21207158 1.922 NM_178728
Napepld
N-acyl phosphatidylethanolamine phospholipase D
chrX_+_50265390 1.877 NM_027642
Phf6
PHD finger protein 6
chr2_+_25036524 1.815 Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_26865431 1.788 NM_029862
5930434B04Rik
RIKEN cDNA 5930434B04 gene
chrX_+_148237785 1.720 NM_021523
Huwe1
HECT, UBA and WWE domain containing 1
chr13_-_55201578 1.720 Uimc1
ubiquitin interaction motif containing 1
chrX_-_92640149 1.615 NM_175179
Fam123b
family with sequence similarity 123, member B
chr19_+_5041341 1.609 NM_134155
Brms1
breast cancer metastasis-suppressor 1
chr6_-_81915918 1.547 NM_026490
Mrpl19
mitochondrial ribosomal protein L19
chr2_+_101518568 1.502 NM_009424
Traf6
TNF receptor-associated factor 6
chr4_+_154338216 1.489 NM_172990
Pank4
pantothenate kinase 4
chr11_-_70468061 1.464 Pfn1
profilin 1
chr1_-_141273617 1.446 NM_133239
Crb1
crumbs homolog 1 (Drosophila)
chr2_-_17970075 1.416 NM_028317
2810030E01Rik
RIKEN cDNA 2810030E01 gene
chr1_-_66864088 1.381 NM_001122738
NM_177645
1110028C15Rik

RIKEN cDNA 1110028C15 gene

chr3_+_159158396 1.376 NM_001172092
NM_001172093
NM_029523
Depdc1a


DEP domain containing 1a


chr5_-_46248719 1.370 NM_001163073
NM_178142
Lcorl

ligand dependent nuclear receptor corepressor-like

chr5_+_136592559 1.350 NM_011293
Polr2j
polymerase (RNA) II (DNA directed) polypeptide J
chr4_+_102243132 1.317 Pde4b
phosphodiesterase 4B, cAMP specific
chr11_-_115353104 1.313 NM_015807
Nt5c
5',3'-nucleotidase, cytosolic
chr5_-_5265981 1.301 Cdk14
cyclin-dependent kinase 14
chr14_-_63379948 1.296 NM_008715
Ints6
integrator complex subunit 6
chr3_-_73512139 1.286 Bche
butyrylcholinesterase
chr2_+_155207542 1.281 Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr1_+_93437120 1.255 NM_001039126
Asb1
ankyrin repeat and SOCS box-containing 1
chr13_-_108680257 1.255 NM_145456
Zswim6
zinc finger, SWIM domain containing 6
chr4_+_154975473 1.254 NM_177186
Slc35e2
solute carrier family 35, member E2
chr3_+_85378033 1.248 NM_144896
Pet112l
PET112-like (yeast)
chr3_+_83570228 1.244 NM_009144
Sfrp2
secreted frizzled-related protein 2
chr14_-_68333666 1.217 NM_001110162
Cdca2
cell division cycle associated 2
chr17_-_35301810 1.141 NM_001199044
NM_020027
Prrc2a

proline-rich coiled-coil 2A

chr6_+_135015679 1.100 NM_181444
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr7_-_109248742 1.067 NM_007491
Art5
ADP-ribosyltransferase 5
chr5_+_31543235 1.067 NM_147201
Nrbp1
nuclear receptor binding protein 1
chr11_+_80196766 1.056 NM_001130169
NM_001130170
NM_001130171
NM_011751
Zfp207



zinc finger protein 207



chr2_+_160471623 0.969 NM_009408
Top1
topoisomerase (DNA) I
chr11_+_79845841 0.954 Suz12
suppressor of zeste 12 homolog (Drosophila)
chr1_+_45368443 0.931 Col3a1
collagen, type III, alpha 1
chr19_+_20676453 0.929 NM_013467
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr17_-_35301791 0.927 Prrc2a
proline-rich coiled-coil 2A
chr13_+_21925611 0.882 NM_001097979
NM_001110555
Hist1h2bj
Hist1h2bq
Hist1h2br
histone cluster 1, H2bj
histone cluster 1, H2bq
histone cluster 1 H2br
chr13_+_16106279 0.875 NM_008380
Inhba
inhibin beta-A
chr5_+_130090042 0.868 NM_011846
Mmp17
matrix metallopeptidase 17
chr3_+_59885811 0.868 Sucnr1
succinate receptor 1
chr8_-_90483392 0.852 NM_033327
Zfp423
zinc finger protein 423
chr6_-_56319574 0.846 NM_001159955
NM_001159956
NM_001159957
Pde1c


phosphodiesterase 1C


chr1_-_179178874 0.846 NM_011785
Akt3
thymoma viral proto-oncogene 3
chr2_+_174276095 0.844 NM_001080971
Tubb1
tubulin, beta 1
chr13_+_42776161 0.844 Phactr1
phosphatase and actin regulator 1
chr11_+_16851377 0.843 NM_176982
Fbxo48
F-box protein 48
chr3_+_66789621 0.838 Rsrc1
arginine/serine-rich coiled-coil 1
chr16_-_34096095 0.823 Kalrn
kalirin, RhoGEF kinase
chr7_+_52253028 0.814 NM_016849
Irf3
interferon regulatory factor 3
chr2_+_103406466 0.803 NM_178890
Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_-_28623006 0.782 NM_010220
Fkbp5
FK506 binding protein 5
chr2_-_74497475 0.779 NM_007967
Evx2
even skipped homeotic gene 2 homolog
chr13_+_98011057 0.770 NM_007930
Enc1
ectodermal-neural cortex 1
chr13_+_51942043 0.767 NM_011817
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr1_-_53813191 0.766


chr19_-_40346058 0.761 NM_016861
Pdlim1
PDZ and LIM domain 1 (elfin)
chr10_+_126437764 0.749 NM_009635
Avil
advillin
chr8_-_72758275 0.746 NM_133972
Armc6
armadillo repeat containing 6
chr7_+_25292105 0.744 NM_146183
Zfp428
zinc finger protein 428
chr2_-_18314387 0.737 NM_001190817
NM_007869
Dnajc1

DnaJ (Hsp40) homolog, subfamily C, member 1

chr10_-_114799212 0.724 NM_133683
Tmem19
transmembrane protein 19
chr9_+_47338449 0.697 Cadm1
cell adhesion molecule 1
chr2_+_80171439 0.686 Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr17_+_8138892 0.685 Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chrX_-_137077639 0.682 NM_010286
Tsc22d3
TSC22 domain family, member 3
chr7_+_146271899 0.681 NM_011993
Dpysl4
dihydropyrimidinase-like 4
chr10_+_128184908 0.678 NM_030100
Wibg
within bgcn homolog (Drosophila)
chr19_-_41068625 0.676 Blnk
B-cell linker
chr13_-_23712946 0.650 NM_001177653
NM_178194
Hist1h2be

histone cluster 1, H2be

chr14_+_55094936 0.644 NM_080726
Rem2
rad and gem related GTP binding protein 2
chr7_+_17460662 0.635 NM_001081655
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr10_-_80813067 0.634 NM_001163165
NM_010440
Hmg20b

high mobility group 20 B

chr11_+_69139759 0.632 NM_010599
Kcnab3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr4_-_110024513 0.631 NM_001163397
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_69735301 0.630 NM_001081548
NM_177783
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr16_+_17045125 0.610 Mapk1
mitogen-activated protein kinase 1
chrX_-_163647057 0.608 Tmsb4x
thymosin, beta 4, X chromosome
chr13_+_17787239 0.604 NM_025479
2810021B07Rik
RIKEN cDNA 2810021B07 gene
chr15_+_81977633 0.600 NM_033218
Srebf2
sterol regulatory element binding factor 2
chr12_+_118997623 0.600 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr4_+_3605207 0.595 NM_001111096
NM_010747
Lyn

Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

chr1_-_186635045 0.588 Mosc1
MOCO sulphurase C-terminal domain containing 1
chr6_-_71582871 0.588 NM_001038695
Kdm3a
lysine (K)-specific demethylase 3A
chr8_+_32260775 0.585 NM_001112729
NM_144927
BC019943

cDNA sequence BC019943

chr15_-_8049142 0.584 Wdr70
WD repeat domain 70
chr14_-_55136145 0.575 NM_013768
Prmt5
protein arginine N-methyltransferase 5
chr13_-_21879086 0.569 NM_178184
Hist1h2an
histone cluster 1, H2an
chr2_-_168032561 0.560 NM_009628
Adnp
activity-dependent neuroprotective protein
chr10_+_21878374 0.558 NM_009016
Raet1a
Raet1e
H60b
retinoic acid early transcript 1, alpha
retinoic acid early transcript 1E
histocompatibility 60b
chr6_-_66987377 0.551 NM_007836
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr10_+_89280918 0.543 Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr7_+_28271928 0.526 NM_018820
Sertad1
SERTA domain containing 1
chr13_+_21826902 0.516 NM_178210
Hist1h4m
Hist1h4j
histone cluster 1, H4m
histone cluster 1, H4j
chr8_+_32297803 0.508 NM_134161
NM_001012517
Fut10

fucosyltransferase 10

chr11_+_115243203 0.507 NM_001080929
Cdr2l
cerebellar degeneration-related protein 2-like
chr12_-_103056971 0.505 Fbln5
fibulin 5
chr12_+_80130149 0.498 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr12_+_52449216 0.492 NM_001015099
NM_001167963
NM_001167964
G2e3


G2/M-phase specific E3 ubiquitin ligase


chr6_+_136467315 0.486 NM_019426
Atf7ip
activating transcription factor 7 interacting protein
chr12_-_55757465 0.480 NM_134054
1110002B05Rik
RIKEN cDNA 1110002B05 gene
chr4_-_106812064 0.479 2210012G02Rik
RIKEN cDNA 2210012G02 gene
chr14_+_51427582 0.473 NM_009632
Parp2
poly (ADP-ribose) polymerase family, member 2
chr10_+_85334563 0.468 NM_133993
Pwp1
PWP1 homolog (S. cerevisiae)
chr12_-_30212990 0.467


chr17_+_71965554 0.450 NM_175639
Wdr43
WD repeat domain 43

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
29.42 1.29e-07 GO:0006334 nucleosome assembly
26.27 3.31e-07 GO:0031497 chromatin assembly
25.81 3.84e-07 GO:0034728 nucleosome organization
25.36 4.43e-07 GO:0065004 protein-DNA complex assembly
19.02 5.23e-07 GO:0006323 DNA packaging
24.12 6.72e-07 GO:0071824 protein-DNA complex subunit organization
23.35 8.75e-07 GO:0006333 chromatin assembly or disassembly
15.19 3.94e-06 GO:0071103 DNA conformation change
6.04 3.53e-04 GO:0006325 chromatin organization
4.60 5.74e-03 GO:0051276 chromosome organization
3.79 3.82e-02 GO:0045892 negative regulation of transcription, DNA-dependent
3.73 4.42e-02 GO:0051253 negative regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
30.02 1.91e-08 GO:0000786 nucleosome
18.86 8.72e-07 GO:0032993 protein-DNA complex
1.95 2.06e-05 GO:0005634 nucleus
7.01 1.69e-03 GO:0000785 chromatin

Gene overrepresentation in function category:

enrichment p-value GO term description
3.36 2.10e-03 GO:0030528 transcription regulator activity
2.50 3.32e-03 GO:0003677 DNA binding
5.29 5.53e-03 GO:0016564 transcription repressor activity