Motif ID: PRRX1,2.p2

Z-value: 1.335

Transcription factors associated with PRRX1,2.p2:

NameEntrezDescription
Prrx1 18933 paired related homeobox 1
Prrx2 20204 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Prrx1chr1_-_165243608-0.261.2e-01Click!
Prrx2chr2_+_30700800-0.115.4e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr5_+_13125413 9.405 LOC100503462
hypothetical LOC100503462
chr8_+_56040211 9.150 Gpm6a
glycoprotein m6a
chr9_+_118387306 8.435 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr8_+_56040193 8.052 Gpm6a
glycoprotein m6a
chr12_+_30219982 7.614 Myt1l
myelin transcription factor 1-like
chr6_+_79968948 7.301 Lrrtm4
leucine rich repeat transmembrane neuronal 4
chr3_+_125106995 7.015 NM_022565
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_55586431 6.793 NM_010750
Mab21l1
mab-21-like 1 (C. elegans)
chr3_-_80606500 6.349 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr15_+_91991704 6.101 NM_001159647
Cntn1
contactin 1
chr16_-_42340613 6.085 NM_008083
Gap43
growth associated protein 43
chr13_-_16115192 5.584 B230303A05Rik
RIKEN cDNA B230303A05 gene
chr2_+_138104219 5.174 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr15_-_56526052 5.132 NM_008216
Has2
hyaluronan synthase 2
chr8_+_56040445 5.124 Gpm6a
glycoprotein m6a
chr2_+_65458814 5.068


chr8_-_3625251 4.967 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr10_+_101621491 4.894 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chr5_-_124053691 4.890 Clip1
CAP-GLY domain containing linker protein 1
chr8_-_70342105 4.866 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr8_-_3624988 4.837 NM_001129804
Pcp2
Purkinje cell protein 2 (L7)
chr3_+_13946371 4.789 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chr2_+_37372112 4.784 NM_177383
Gpr21
G protein-coupled receptor 21
chr1_+_189821727 4.717 NM_011935
Esrrg
estrogen-related receptor gamma
chr2_+_70312979 4.698 NM_022435
Sp5
trans-acting transcription factor 5
chr2_+_61642509 4.639 NM_009322
Tbr1
T-box brain gene 1
chr3_-_95032039 4.516 Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_152645143 4.491 NM_012028
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr3_-_80606641 4.480 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr9_-_58049765 4.349 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_-_80606598 4.343 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr8_+_24780132 4.281 NM_177086
Zmat4
zinc finger, matrin type 4
chr11_+_93905501 4.252 NM_001025428
NM_001025429
NM_001025430
Spag9


sperm associated antigen 9


chr9_-_29770699 4.203 NM_172290
Ntm
neurotrimin
chr6_-_13789847 4.100 NM_145066
Gpr85
G protein-coupled receptor 85
chr1_-_167865030 4.072 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chr11_+_42234760 3.765 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr10_-_88067758 3.720 NM_175418
Mybpc1
myosin binding protein C, slow-type
chr15_-_8660462 3.670 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_79436564 3.654 NM_009129
Scg2
secretogranin II
chr19_-_17912073 3.633 NM_001163144
NM_001190483
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr7_-_80686630 3.408 NM_001081345
Chd2
chromodomain helicase DNA binding protein 2
chr4_-_35792385 3.363 NM_001166001
NM_175516
Lingo2

leucine rich repeat and Ig domain containing 2

chrM_+_13320 3.277


chr1_-_157264398 3.250 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr4_+_97248556 3.203 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr1_-_160286359 3.151 NM_207583
Fam5b
family with sequence similarity 5, member B
chr2_-_79296732 3.141 NM_010894
Neurod1
neurogenic differentiation 1
chr2_-_77541328 3.083 NM_001113399
Zfp385b
zinc finger protein 385B
chr7_+_152024499 3.038 NM_008007
Fgf3
fibroblast growth factor 3
chr9_+_113721698 3.012 NM_001081960
NM_029633
Clasp2

CLIP associating protein 2

chr11_-_41814008 2.919 NM_008073
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr9_-_58049842 2.912 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_55631085 2.910 Neurod6
neurogenic differentiation 6
chr15_-_8660442 2.884 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_77192615 2.881 NM_028880
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr2_-_65405546 2.765 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr16_+_96689322 2.736


chr2_-_7317513 2.728 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr5_+_19413335 2.657 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr13_+_20564928 2.597 NM_198093
Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr9_-_58050091 2.467 NM_001161536
NM_177193
NM_001161539
Islr2


immunoglobulin superfamily containing leucine-rich repeat 2


chr7_+_134094045 2.464 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr4_+_101927543 2.348 NM_019840
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_+_148344816 2.347 NM_001145807
Fam5c
family with sequence similarity 5, member C
chrX_-_161765324 2.339 Glra2
glycine receptor, alpha 2 subunit
chr6_-_138371302 2.336 Lmo3
LIM domain only 3
chr4_-_63707964 2.334 Tnc
tenascin C
chr8_+_115093942 2.333 NM_130457
Cntnap4
contactin associated protein-like 4
chr6_+_17699145 2.309 NM_001083315
NM_022332
St7

suppression of tumorigenicity 7

chr18_-_31606908 2.300 NM_009308
Syt4
synaptotagmin IV
chr7_+_98239427 2.299 Dlg2
discs, large homolog 2 (Drosophila)
chrX_-_147091911 2.293 NM_001002272
NM_019548
Tro

trophinin

chr11_-_30168153 2.284 Spnb2
spectrin beta 2
chr13_+_58909236 2.282 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr17_+_80706746 2.264 NM_001145452
Arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr12_+_110798661 2.262 Meg3
maternally expressed 3
chr15_-_8660479 2.236 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_100286446 2.234 Mtap1b
microtubule-associated protein 1B
chr7_+_97535490 2.171 NM_001040087
NM_001040088
Sytl2

synaptotagmin-like 2

chr1_+_66368571 2.165 Mtap2
microtubule-associated protein 2
chr10_-_24919916 2.164 Akap7
A kinase (PRKA) anchor protein 7
chr14_-_109313298 2.122 Slitrk1
SLIT and NTRK-like family, member 1
chr12_+_53800302 2.109 Akap6
A kinase (PRKA) anchor protein 6
chr1_+_70772288 2.103 NM_177164
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr16_-_23520662 2.090 NM_008555
Masp1
mannan-binding lectin serine peptidase 1
chr17_-_90487479 2.055 Nrxn1
neurexin I
chr6_-_55631039 2.047 Neurod6
neurogenic differentiation 6
chr14_+_84843366 2.040 NM_001013753
Pcdh17
protocadherin 17
chr3_+_8509479 2.016 NM_025285
Stmn2
stathmin-like 2
chr10_+_73284612 2.001 NM_001142735
NM_001142736
NM_001142737
NM_001142738
NM_001142739
NM_001142740
NM_001142741
NM_001142742
NM_001142743
NM_001142746
NM_001142747
NM_001142748
NM_001142760
NM_023115
Pcdh15













protocadherin 15













chr10_-_33344405 1.985 NM_175448
Clvs2
clavesin 2
chr4_+_109015660 1.965 NM_001159964
Eps15
epidermal growth factor receptor pathway substrate 15
chr12_+_25659777 1.961 NM_001081378
Kidins220
kinase D-interacting substrate 220
chrM_+_11741 1.940 ND5
NADH dehydrogenase subunit 5
chr3_-_151856766 1.937 NM_025926
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr12_-_32398730 1.933 NM_175191
Gpr22
G protein-coupled receptor 22
chr14_+_66963139 1.931 NM_019675
Stmn4
stathmin-like 4
chr11_-_33103458 1.929 NM_019916
Tlx3
T-cell leukemia, homeobox 3
chr11_+_78640059 1.890 NM_001076681
1810012P15Rik
RIKEN cDNA 1810012P15 gene
chr18_+_37460452 1.884 NM_053128
Pcdhb3
protocadherin beta 3
chr11_+_77744280 1.882 NM_021286
Sez6
seizure related gene 6
chrM_+_14143 1.860


chr15_-_37389073 1.851 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr8_-_42140113 1.838 NM_001005864
Mtus1
mitochondrial tumor suppressor 1
chr7_+_62090867 1.837 Luzp2
leucine zipper protein 2
chr16_-_23890909 1.837 NM_009215
Sst
somatostatin
chr11_+_93905443 1.804 Spag9
sperm associated antigen 9
chr11_+_23978110 1.780 Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr8_-_63433528 1.745 NM_173876
Clcn3
chloride channel 3
chr1_-_171677653 1.707 NM_009062
Rgs4
regulator of G-protein signaling 4
chr9_-_60497537 1.688 Lrrc49
leucine rich repeat containing 49
chr10_-_101953046 1.683 NM_024435
Nts
neurotensin
chr18_+_37133455 1.681 NM_009957
Pcdha7
protocadherin alpha 7
chr15_+_4325490 1.676 NM_177355
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr13_-_100286521 1.676 NM_008634
Mtap1b
microtubule-associated protein 1B
chr9_-_40153864 1.662 Gramd1b
GRAM domain containing 1B
chr14_+_122879276 1.662 Zic2
zinc finger protein of the cerebellum 2
chr3_+_67696141 1.655 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr12_+_110783593 1.637 Meg3
maternally expressed 3
chrX_+_111587911 1.633 NM_172781
Klhl4
kelch-like 4 (Drosophila)
chr16_-_88290458 1.618 NM_010348
NM_146072
Grik1

glutamate receptor, ionotropic, kainate 1

chr3_-_10440061 1.608 NM_001127191
NM_029068
Snx16

sorting nexin 16

chr10_+_99478457 1.605 NM_013598
Kitl
kit ligand
chr9_-_53823107 1.578 NM_177769
Elmod1
ELMO domain containing 1
chr4_+_15808409 1.574 NM_009788
Calb1
calbindin 1
chr16_-_95680627 1.568


chr9_-_58049521 1.554 NM_001161535
NM_001161537
NM_001161540
Islr2


immunoglobulin superfamily containing leucine-rich repeat 2


chr2_-_6805937 1.547 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr2_+_143371807 1.535 NM_008792
Pcsk2
proprotein convertase subtilisin/kexin type 2
chrM_+_13998 1.535


chr13_+_58909168 1.527 NM_001025074
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr2_+_69058005 1.515 NM_021331
G6pc2
glucose-6-phosphatase, catalytic, 2
chr2_+_121184334 1.507 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr8_+_65430028 1.497 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr13_-_36826245 1.492 NM_153529
Nrn1
neuritin 1
chrX_+_166123130 1.471 NM_010797
Mid1
midline 1
chr18_-_6516073 1.465 NM_007935
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr12_+_83717883 1.430 NM_015812
Rgs6
regulator of G-protein signaling 6
chrX_-_85360961 1.415 NM_001160403
Il1rapl1
interleukin 1 receptor accessory protein-like 1
chr13_+_8202111 1.398 NM_052977
Adarb2
adenosine deaminase, RNA-specific, B2
chr9_+_37175190 1.397 NM_175189
Hepacam
hepatocyte cell adhesion molecule
chr7_+_98239230 1.387 NM_011807
Dlg2
discs, large homolog 2 (Drosophila)
chr1_+_81073778 1.385 NM_172849
9430031J16Rik
RIKEN cDNA 9430031J16 gene
chr8_-_39724524 1.377 NM_145841
Sgcz
sarcoglycan zeta
chr3_-_80606704 1.372 NM_001039195
NM_001083806
NM_013540
Gria2


glutamate receptor, ionotropic, AMPA2 (alpha 2)


chr18_-_15309939 1.371 NM_134112
Kctd1
potassium channel tetramerisation domain containing 1
chr8_+_96335202 1.366 Gnao1
guanine nucleotide binding protein, alpha O
chr12_+_30219769 1.362 NM_001093776
Myt1l
myelin transcription factor 1-like
chr19_+_8665743 1.360 NM_001164634
NM_031194
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr18_+_37678006 1.352 NM_053147
Pcdhb22
protocadherin beta 22
chr1_+_97230610 1.345 Fam174a
family with sequence similarity 174, member A
chrX_-_140367467 1.335 NM_001110222
NM_001110223
NM_001110224
NM_010025
Dcx



doublecortin



chr10_+_42580317 1.334 NM_172938
Scml4
sex comb on midleg-like 4 (Drosophila)
chr4_+_28740314 1.330 Epha7
Eph receptor A7
chr14_-_111154292 1.320 NM_175499
Slitrk6
SLIT and NTRK-like family, member 6
chr14_+_120674921 1.317 Mbnl2
muscleblind-like 2
chr18_+_23656024 1.311 Dtna
dystrobrevin alpha
chr5_+_107926763 1.284 NM_001007574
NM_001168557
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr17_-_35975148 1.279 NM_011655
Tubb5
tubulin, beta 5
chr19_+_26822892 1.270 NM_026003
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_+_46593141 1.251 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr6_-_119913623 1.248 Wnk1
WNK lysine deficient protein kinase 1
chr15_+_81767188 1.246 NM_145473
Csdc2
cold shock domain containing C2, RNA binding
chr19_+_4711207 1.244 Spnb3
spectrin beta 3
chr15_+_22966203 1.238 NM_001081299
Cdh18
cadherin 18
chr5_-_135223110 1.236 NM_007925
Eln
elastin
chrM_+_2750 1.234


chr18_+_64425037 1.229 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_-_161764912 1.226 NM_183427
Glra2
glycine receptor, alpha 2 subunit
chr4_+_28740280 1.224 NM_001122889
NM_010141
Epha7

Eph receptor A7

chr12_-_84828657 1.223 NM_058212
Dpf3
D4, zinc and double PHD fingers, family 3
chr17_-_14831095 1.213 Thbs2
thrombospondin 2
chr9_+_94570310 1.211 NM_177909
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr8_-_101940218 1.192 NM_001039154
NM_007667
Cdh8

cadherin 8

chr7_+_109371529 1.189 NM_145583
Pgap2
post-GPI attachment to proteins 2
chr18_+_37633193 1.178 NM_053140
Pcdhb15
protocadherin beta 15
chr15_-_101573522 1.177 NM_019956
Krt71
keratin 71
chr6_+_103460834 1.176 NM_007697
Chl1
cell adhesion molecule with homology to L1CAM
chr2_-_84265422 1.176 NM_018782
Calcrl
calcitonin receptor-like
chr11_-_98590680 1.169 NM_011869
Med24
mediator complex subunit 24
chr4_-_82151180 1.150 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chrX_+_35954355 1.142 Mcts1
malignant T cell amplified sequence 1
chr11_-_30168142 1.140 Spnb2
spectrin beta 2
chr7_+_77509969 1.140 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr2_+_180332926 1.133 NM_009936
Col9a3
collagen, type IX, alpha 3
chr5_+_27588462 1.129 NM_001136060
Dpp6
dipeptidylpeptidase 6
chr16_-_22439642 1.128 NM_023794
Etv5
ets variant gene 5
chr11_+_69831951 1.124 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr5_-_5265598 1.124 Cdk14
cyclin-dependent kinase 14
chr5_-_84846348 1.121 NM_007937
Epha5
Eph receptor A5
chr4_+_101180625 1.118 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_-_97372344 1.104 Srcin1
SRC kinase signaling inhibitor 1
chr3_-_86352170 1.093 NM_011839
Mab21l2
mab-21-like 2 (C. elegans)
chrX_+_16196823 1.085 NM_173740
Maoa
monoamine oxidase A
chr4_+_102262447 1.080 NM_001177981
Pde4b
phosphodiesterase 4B, cAMP specific
chr12_-_119474010 1.079 Sp4
trans-acting transcription factor 4
chr18_-_38129384 1.067 NM_175684
Fchsd1
FCH and double SH3 domains 1
chr14_+_14286471 1.067 NM_001163032
Synpr
synaptoporin
chr19_+_38339167 1.061 NM_020278
Lgi1
leucine-rich repeat LGI family, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
3.85 6.14e-10 GO:0007399 nervous system development
4.60 3.89e-09 GO:0048699 generation of neurons
7.26 1.18e-08 GO:0000904 cell morphogenesis involved in differentiation
2.65 1.36e-08 GO:0048731 system development
4.31 1.87e-08 GO:0022008 neurogenesis
7.75 1.91e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.37 7.46e-07 GO:0048856 anatomical structure development
2.17 2.63e-06 GO:0032502 developmental process
2.24 2.75e-06 GO:0007275 multicellular organismal development
5.23 2.94e-06 GO:0000902 cell morphogenesis
5.14 1.01e-05 GO:0048666 neuron development
4.81 1.15e-05 GO:0032989 cellular component morphogenesis
4.53 1.26e-05 GO:0030182 neuron differentiation
6.49 2.53e-05 GO:0048812 neuron projection morphogenesis
6.91 3.77e-05 GO:0007409 axonogenesis
5.75 4.00e-05 GO:0048858 cell projection morphogenesis
5.64 5.18e-05 GO:0032990 cell part morphogenesis
2.44 7.94e-05 GO:0030154 cell differentiation
5.43 8.53e-05 GO:0031175 neuron projection development
1.48 1.43e-04 GO:0065007 biological regulation
2.37 1.73e-04 GO:0048869 cellular developmental process
3.32 3.06e-04 GO:0048468 cell development
4.80 4.15e-04 GO:0051960 regulation of nervous system development
5.60 4.30e-04 GO:0045664 regulation of neuron differentiation
3.72 6.05e-04 GO:0007155 cell adhesion
1.49 6.51e-04 GO:0050794 regulation of cellular process
3.69 6.86e-04 GO:0022610 biological adhesion
4.34 1.44e-03 GO:0007267 cell-cell signaling
3.95 2.22e-03 GO:0030030 cell projection organization
14.41 2.41e-03 GO:0050806 positive regulation of synaptic transmission
1.44 2.42e-03 GO:0050789 regulation of biological process
4.65 3.40e-03 GO:0050767 regulation of neurogenesis
13.31 3.88e-03 GO:0051971 positive regulation of transmission of nerve impulse
1.94 4.60e-03 GO:0016043 cellular component organization
12.36 6.01e-03 GO:0031646 positive regulation of neurological system process
27.13 8.16e-03 GO:0007026 negative regulation of microtubule depolymerization
25.62 1.04e-02 GO:0031114 regulation of microtubule depolymerization
2.43 1.04e-02 GO:0009653 anatomical structure morphogenesis
15.58 1.10e-02 GO:0031110 regulation of microtubule polymerization or depolymerization
1.86 1.44e-02 GO:0071840 cellular component organization or biogenesis
2.32 1.66e-02 GO:0051239 regulation of multicellular organismal process
14.06 1.84e-02 GO:0043242 negative regulation of protein complex disassembly
3.17 1.90e-02 GO:0007154 cell communication
3.86 2.43e-02 GO:0060284 regulation of cell development
19.22 3.48e-02 GO:0031111 negative regulation of microtubule polymerization or depolymerization
1.57 3.56e-02 GO:0032501 multicellular organismal process
11.53 4.89e-02 GO:0043244 regulation of protein complex disassembly

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.99 1.39e-08 GO:0043005 neuron projection
5.32 2.69e-08 GO:0045202 synapse
2.12 6.78e-08 GO:0071944 cell periphery
2.10 2.30e-07 GO:0005886 plasma membrane
6.07 4.51e-06 GO:0030425 dendrite
5.77 7.07e-05 GO:0030424 axon
5.02 1.36e-04 GO:0043025 neuronal cell body
4.85 2.02e-04 GO:0044456 synapse part
2.85 2.04e-04 GO:0042995 cell projection
4.78 2.40e-04 GO:0044297 cell body
2.21 1.87e-03 GO:0044459 plasma membrane part
2.54 2.62e-03 GO:0000267 cell fraction
2.72 4.84e-03 GO:0005626 insoluble fraction
1.38 8.39e-03 GO:0016020 membrane
1.45 8.43e-03 GO:0044425 membrane part
8.54 1.17e-02 GO:0030426 growth cone
5.73 1.30e-02 GO:0045211 postsynaptic membrane
3.03 1.31e-02 GO:0030054 cell junction
8.34 1.34e-02 GO:0014069 postsynaptic density
8.24 1.43e-02 GO:0030427 site of polarized growth
1.17 1.64e-02 GO:0005623 cell
1.17 1.64e-02 GO:0044464 cell part
2.58 2.40e-02 GO:0005624 membrane fraction

Gene overrepresentation in function category:

enrichment p-value GO term description
1.63 1.89e-04 GO:0005515 protein binding
3.85 2.50e-02 GO:0016563 transcription activator activity
5.90 3.30e-02 GO:0008509 anion transmembrane transporter activity
76.85 3.84e-02 GO:0005519 cytoskeletal regulatory protein binding
9.01 3.97e-02 GO:0005230 extracellular ligand-gated ion channel activity