• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: REST.p3

Z-value: 4.504

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr6_+_113232319	105.171		Cpne9	copine family member IX
chr4_+_15808409	98.935	NM_009788	Calb1	calbindin 1
chr16_-_23890909	69.865	NM_009215	Sst	somatostatin
chr2_-_25174498	65.817		Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr2_-_25174662	60.277	NM_001177656 NM_001177657 NM_008169	Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr4_-_128798481	54.038	NM_010471	Hpca	hippocalcin
chrX_+_7215705	51.376	NM_009305	Syp	synaptophysin
chr3_-_80606500	49.212		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr5_+_137506122	47.913	NM_001039385	Vgf	VGF nerve growth factor inducible
chr11_+_77744280	43.555	NM_021286	Sez6	seizure related gene 6
chr2_+_155601077	43.093	NM_010808	Mmp24	matrix metallopeptidase 24
chrX_-_20498021	41.811	NM_001110780 NM_013680	Syn1	synapsin I
chr1_-_84692750	39.431	NM_152915	Dner	delta/notch-like EGF-related receptor
chr1_-_84692352	37.187		Dner	delta/notch-like EGF-related receptor
chr7_+_28438881	36.475	NM_028417	Ttc9b	tetratricopeptide repeat domain 9B
chr2_+_132607013	36.413	NM_007694	Chgb	chromogranin B
chr3_-_80606598	34.878		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr3_-_80606641	33.972		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr1_+_81073778	32.971	NM_172849	9430031J16Rik	RIKEN cDNA 9430031J16 gene
chr16_-_37384915	32.831		Stxbp5l	syntaxin binding protein 5-like
chr18_-_31606908	31.712	NM_009308	Syt4	synaptotagmin IV
chr17_-_91492065	30.513	NM_020252 NM_177284	Nrxn1	neurexin I
chr11_+_80290509	29.976	NM_009871	Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr12_+_103793130	29.919	NM_007693	Chga	chromogranin A
chr9_+_40076800	28.631	NM_001083917 NM_153522 NM_178227	Scn3b	sodium channel, voltage-gated, type III, beta
chr2_-_181048957	28.368		Stmn3	stathmin-like 3
chr16_-_37385024	26.684	NM_001114611 NM_001114612 NM_001114613 NM_172440	Stxbp5l	syntaxin binding protein 5-like
chr9_-_57315800	26.275	NM_020270	Scamp5	secretory carrier membrane protein 5
chr13_+_54472705	25.955	NM_009946	Cplx2	complexin 2
chr6_-_121423633	25.743		Iqsec3	IQ motif and Sec7 domain 3
chr3_-_80606704	25.382	NM_001039195 NM_001083806 NM_013540	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr5_-_121459496	23.985	NM_011286	Rph3a	rabphilin 3A
chr2_+_164793796	23.701		Slc12a5	solute carrier family 12, member 5
chr2_+_164793698	23.533		Slc12a5	solute carrier family 12, member 5
chr11_-_35612058	23.272		Fbll1	fibrillarin-like 1
chr2_-_92241357	21.517	NM_011162	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr11_+_80290571	20.854		Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_-_177422630	17.210	NM_001199003 NM_011880	Rgs7	regulator of G protein signaling 7
chr6_-_121423682	15.479	NM_001033354	Iqsec3	IQ motif and Sec7 domain 3
chr7_-_88638789	14.303	NM_021492	Ap3b2	adaptor-related protein complex 3, beta 2 subunit
chr17_-_25377052	14.081	NM_172529	Gnptg	N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr2_-_92241282	13.316		Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr15_-_76552594	12.898	NM_198119	Lrrc24	leucine rich repeat containing 24
chr1_+_34636537	12.404	NM_213727	Fam123c	family with sequence similarity 123, member C
chr10_-_3557441	11.850	NM_001039652	Oprm1	opioid receptor, mu 1
chr12_-_113749363	11.764	NM_178915	Tmem179	transmembrane protein 179
chr12_-_71448300	11.747		Trim9	tripartite motif-containing 9
chr12_+_117724239	11.604		Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr2_+_22478062	11.565		Gad2	glutamic acid decarboxylase 2
chr7_-_88638540	11.230		Ap3b2	adaptor-related protein complex 3, beta 2 subunit
chr1_+_161453899	10.807	NM_022312	Tnr	tenascin R
chr3_+_114606995	10.306	NM_153458	Olfm3	olfactomedin 3
chr6_+_113232300	9.817	NM_170673	Cpne9	copine family member IX
chr12_-_113749313	9.144		Tmem179	transmembrane protein 179
chr12_-_86039703	9.018	NM_001033334	Tmem90a	transmembrane protein 90a
chr2_+_132607432	8.985		Chgb	chromogranin B
chr2_-_79294977	8.554		Neurod1	neurogenic differentiation 1
chr9_+_122026378	8.231	NM_001164572 NM_133741	Snrk	SNF related kinase
chr13_-_105844882	7.447	NM_029879	Rgs7bp	regulator of G-protein signalling 7 binding protein
chr4_+_128814102	7.406	NM_027402	Fndc5	fibronectin type III domain containing 5
chr13_-_54850954	7.006	NM_012014	Gprin1	G protein-regulated inducer of neurite outgrowth 1
chr6_+_117118552	6.982	NM_001012477 NM_013655 NM_021704	Cxcl12	chemokine (C-X-C motif) ligand 12
chr17_+_70318387	6.950		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr12_+_117724182	6.902	NM_011215	Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr14_+_66587319	6.882	NM_013492	Clu	clusterin
chr1_-_75176703	6.777	NM_023732	Abcb6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_22213516	6.759	NM_001035239 NM_001035240 NM_001035241 NM_001035242 NM_001035243	Trpm3	transient receptor potential cation channel, subfamily M, member 3
chr11_+_74433092	6.661	NM_001013784	E130309D14Rik	RIKEN cDNA E130309D14 gene
chr10_+_90292388	6.463		Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr17_+_70318707	5.979		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr7_-_88638744	5.627		Ap3b2	adaptor-related protein complex 3, beta 2 subunit
chr2_+_139996381	5.567	NM_027093	2310003L22Rik	RIKEN cDNA 2310003L22 gene
chr5_-_121459315	4.907		Rph3a	rabphilin 3A
chr11_+_102254699	4.409	NM_016759	Rundc3a	RUN domain containing 3A
chr14_-_50145396	4.295	NM_029238	Slc35f4	solute carrier family 35, member F4
chr8_+_18846262	4.278	NM_026792	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr12_+_121184294	3.980	NM_001160385	Tmem196	transmembrane protein 196
chr17_+_70318530	3.851		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr17_-_71339826	3.776	NM_023402	Myl12b	myosin, light chain 12B, regulatory
chr19_+_5038825	3.639	NM_175383	B3gnt1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr10_+_90292453	3.417		Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr2_+_22478131	2.829		Gad2	glutamic acid decarboxylase 2
chr16_-_17576750	2.821	NM_144852	Slc7a4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr6_+_8898613	2.652		Nxph1	neurexophilin 1
chr17_-_23877115	2.565	NM_023824	Paqr4	progestin and adipoQ receptor family member IV
chr7_-_20189709	2.500	NM_016680	Clasrp	CLK4-associating serine/arginine rich protein
chr11_-_117734712	2.475	NM_027919	Tha1	threonine aldolase 1
chr9_-_21889841	2.461		Ecsit	ECSIT homolog (Drosophila)
chr12_+_117724251	2.398		Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr19_+_47253484	2.378		Neurl1a	neuralized homolog 1A (Drosophila)
chr8_+_18846471	2.321		Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr17_+_70318760	2.127		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr13_+_45602938	2.103
chr4_-_135050358	1.891	NM_028995	Nipal3	NIPA-like domain containing 3
chr2_-_26997965	1.878	NM_175427	Fam163b	family with sequence similarity 163, member B
chr9_+_40609317	1.779	NM_031165	Hspa8	heat shock protein 8
chr9_-_21889810	1.732	NM_012029	Ecsit	ECSIT homolog (Drosophila)
chr9_+_108728650	1.491	NM_080437	Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr19_+_42330170	1.475	NM_027694	Golga7b	golgi autoantigen, golgin subfamily a, 7B
chr3_-_89568552	1.408	NM_009602	Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr11_+_76485971	1.303	NM_177182	Bhlha9	basic helix-loop-helix family, member a9
chr3_-_89568525	1.289		Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr2_+_32502186	1.160		Eng	endoglin
chr4_+_12833983	1.055	NM_001171801 NM_173746	Gm11818	predicted gene 11818
chr19_+_47253626	1.050		Neurl1a	neuralized homolog 1A (Drosophila)
chr2_+_132607398	1.032		Chgb	chromogranin B
chr8_+_18846524	0.949		Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr10_-_126558207	0.853	NM_001171026 NM_177614	Os9	amplified in osteosarcoma
chr18_-_33373324	0.772		Stard4	StAR-related lipid transfer (START) domain containing 4
chr17_+_24686778	0.709	NM_013630	Pkd1	polycystic kidney disease 1 homolog
chr5_+_117570113	0.693		Taok3	TAO kinase 3
chr4_-_4065205	0.652		Penk	preproenkephalin
chr1_-_177422520	0.639		Rgs7	regulator of G protein signaling 7
chr1_-_164478475	0.501	NM_144877	Mettl13	methyltransferase like 13
chr5_-_122915995	0.398		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_139996419	0.290		2310003L22Rik	RIKEN cDNA 2310003L22 gene
chr9_-_113562893	0.285		Pdcd6ip	programmed cell death 6 interacting protein
chr11_-_115465172	0.242	NM_173048	Gga3	golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr11_-_74710462	0.147		Sgsm2	small G protein signaling modulator 2
chr3_-_89568298	0.142		Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr1_-_177555593	0.044	NM_010209	Fh1	fumarate hydratase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
13.91	2.92e-09	GO:0007268	synaptic transmission
10.38	3.97e-09	GO:0007267	cell-cell signaling
11.01	5.41e-08	GO:0019226	transmission of nerve impulse
11.01	5.41e-08	GO:0035637	multicellular organismal signaling
10.62	4.50e-07	GO:0046903	secretion
6.69	1.74e-06	GO:0007154	cell communication
20.25	2.19e-06	GO:0003001	generation of a signal involved in cell-cell signaling
20.25	2.19e-06	GO:0023061	signal release
12.21	3.27e-06	GO:0032940	secretion by cell
25.41	4.27e-06	GO:0001505	regulation of neurotransmitter levels
37.61	4.58e-06	GO:0007269	neurotransmitter secretion
2.67	7.09e-05	GO:0051179	localization
18.19	3.79e-04	GO:0006836	neurotransmitter transport
2.66	1.42e-03	GO:0006810	transport
2.62	1.91e-03	GO:0051234	establishment of localization
4.47	2.09e-03	GO:0051649	establishment of localization in cell
11.83	4.65e-03	GO:0007626	locomotory behavior
275.73	5.36e-03	GO:0007158	neuron cell-cell adhesion
26.27	6.46e-03	GO:0048489	synaptic vesicle transport
8.59	6.74e-03	GO:0031644	regulation of neurological system process
4.27	7.90e-03	GO:0022008	neurogenesis
2.96	8.18e-03	GO:0065008	regulation of biological quality
3.74	1.37e-02	GO:0051641	cellular localization
3.50	1.39e-02	GO:0007399	nervous system development
4.78	1.66e-02	GO:0016192	vesicle-mediated transport
4.18	2.23e-02	GO:0048699	generation of neurons
3.57	2.25e-02	GO:0010646	regulation of cell communication
8.63	2.75e-02	GO:0050804	regulation of synaptic transmission
11.70	2.77e-02	GO:0006887	exocytosis
35.98	3.14e-02	GO:0016079	synaptic vesicle exocytosis
35.98	3.14e-02	GO:0017158	regulation of calcium ion-dependent exocytosis
137.87	3.20e-02	GO:0001661	conditioned taste aversion
5.47	4.09e-02	GO:0048666	neuron development
8.01	4.17e-02	GO:0051969	regulation of transmission of nerve impulse
31.83	4.57e-02	GO:0050807	regulation of synapse organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
9.84	8.52e-11	GO:0045202	synapse
7.96	1.05e-08	GO:0043005	neuron projection
10.78	1.89e-08	GO:0044456	synapse part
22.29	2.73e-07	GO:0008021	synaptic vesicle
17.01	2.89e-07	GO:0030136	clathrin-coated vesicle
4.99	3.74e-07	GO:0042995	cell projection
14.96	8.93e-07	GO:0030135	coated vesicle
7.15	2.66e-06	GO:0016023	cytoplasmic membrane-bounded vesicle
6.78	5.03e-06	GO:0031988	membrane-bounded vesicle
5.58	1.58e-05	GO:0031410	cytoplasmic vesicle
1.78	1.65e-05	GO:0016020	membrane
5.89	2.55e-05	GO:0030054	cell junction
5.25	3.34e-05	GO:0031982	vesicle
8.17	3.84e-05	GO:0044297	cell body
8.72	9.06e-05	GO:0030425	dendrite
25.54	1.61e-04	GO:0030665	clathrin coated vesicle membrane
7.72	2.48e-04	GO:0043025	neuronal cell body
38.04	3.82e-04	GO:0030672	synaptic vesicle membrane
19.71	5.88e-04	GO:0030662	coated vesicle membrane
17.03	1.21e-03	GO:0030426	growth cone
2.24	1.28e-03	GO:0005886	plasma membrane
16.43	1.44e-03	GO:0030427	site of polarized growth
1.76	1.62e-03	GO:0044425	membrane part
2.19	1.91e-03	GO:0071944	cell periphery
10.55	2.40e-03	GO:0030659	cytoplasmic vesicle membrane
10.23	2.86e-03	GO:0044433	cytoplasmic vesicle part
9.58	4.14e-03	GO:0012506	vesicle membrane
7.44	4.57e-03	GO:0030424	axon
3.40	5.05e-03	GO:0000267	cell fraction
2.73	1.13e-02	GO:0044459	plasma membrane part
5.39	1.22e-02	GO:0044463	cell projection part
3.57	2.41e-02	GO:0005624	membrane fraction
8.58	3.20e-02	GO:0045211	postsynaptic membrane
3.41	3.57e-02	GO:0005626	insoluble fraction
68.94	3.98e-02	GO:0061200	clathrin sculpted gamma-aminobutyric acid transport vesicle
68.94	3.98e-02	GO:0061202	clathrin sculpted gamma-aminobutyric acid transport vesicle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
6.06	1.44e-04	GO:0005509	calcium ion binding