Motif ID: SOX17.p2

Z-value: 3.271

Transcription factors associated with SOX17.p2:

NameEntrezDescription
Sox17 20671 SRY-box containing gene 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Sox17chr1_-_4486443-0.261.3e-01Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr7_-_56892061 49.341 NM_001005232
Dbx1
developing brain homeobox 1
chr2_+_181498036 38.949 NM_001171615
Myt1
myelin transcription factor 1
chr5_-_138721164 30.280 NM_172412
Gpc2
glypican 2 (cerebroglycan)
chr16_+_52031733 30.127 Cblb
Casitas B-lineage lymphoma b
chr16_+_52031704 29.127 Cblb
Casitas B-lineage lymphoma b
chrX_+_108009728 28.059 NM_008901
Pou3f4
POU domain, class 3, transcription factor 4
chr1_-_140739020 25.432 NM_001025565
NM_001042577
Lhx9

LIM homeobox protein 9

chr16_-_17125198 25.362 NM_183287
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr4_+_124334876 22.890 NM_011141
Pou3f1
POU domain, class 3, transcription factor 1
chr4_+_13670582 20.622 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_12980994 19.122 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr10_+_17516024 17.960 NM_138628
Txlnb
taxilin beta
chr13_-_56353523 17.342 NM_010896
Neurog1
neurogenin 1
chr6_+_17699145 15.645 NM_001083315
NM_022332
St7

suppression of tumorigenicity 7

chr5_+_111846284 15.504 Mn1
meningioma 1
chr2_-_30329737 15.395 Ier5l
immediate early response 5-like
chr3_+_127336055 14.827 NM_009718
Neurog2
neurogenin 2
chr6_+_47194393 14.780 NM_025771
Cntnap2
contactin associated protein-like 2
chr7_-_150646883 14.735 NM_001161624
NM_009876
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr10_+_84218792 14.517 NM_001024918
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr4_+_154335029 14.412 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr1_+_9591550 14.207 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chrX_+_55283804 13.895 NM_009575
Zic3
zinc finger protein of the cerebellum 3
chr3_+_87774988 13.731 NM_016701
Nes
nestin
chr11_-_11937330 13.558 NM_010345
Grb10
growth factor receptor bound protein 10
chr14_-_104867215 12.528 NM_011143
Pou4f1
POU domain, class 4, transcription factor 1
chr18_-_75120759 12.503 NM_010720
Lipg
lipase, endothelial
chr1_+_134212642 12.279 NM_001195025
NM_028778
Nuak2

NUAK family, SNF1-like kinase, 2

chr2_-_73613381 12.113 NM_001113246
NM_001166603
Chn1

chimerin (chimaerin) 1

chr2_-_30329717 11.665 NM_030244
Ier5l
immediate early response 5-like
chr11_+_32176599 11.659 NM_010405
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr15_+_98620287 11.577 NM_021279
Wnt1
wingless-related MMTV integration site 1
chr15_-_90880241 11.367 NM_001109040
NM_001109041
NM_001109042
NM_016705
Kif21a



kinesin family member 21A



chr13_-_96388378 11.188 NM_010169
F2r
coagulation factor II (thrombin) receptor
chr2_+_25036276 10.782 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr5_-_67490295 10.768 NM_008888
Phox2b
paired-like homeobox 2b
chr3_-_115832327 10.673 Vcam1
vascular cell adhesion molecule 1
chr4_-_6917628 10.568 NM_145711
Tox
thymocyte selection-associated high mobility group box
chr1_+_135142673 10.148 NM_001160268
NM_182930
Plekha6

pleckstrin homology domain containing, family A member 6

chr3_+_87775081 9.832 Nes
nestin
chr7_+_30088984 9.584 NM_013874
Dpf1
D4, zinc and double PHD fingers family 1
chr1_+_131170034 9.512 Thsd7b
thrombospondin, type I, domain containing 7B
chr13_-_96388412 9.467 F2r
coagulation factor II (thrombin) receptor
chr16_-_45724422 9.430 NM_019754
Tagln3
transgelin 3
chr2_+_13495931 9.377 NM_011701
Vim
vimentin
chr6_-_97567511 9.174 NM_145148
Frmd4b
FERM domain containing 4B
chr2_+_34627607 9.135 NM_001163434
NM_022310
Hspa5

heat shock protein 5

chr11_+_68505612 9.126 Myh10
myosin, heavy polypeptide 10, non-muscle
chr11_+_93905557 9.118 Spag9
sperm associated antigen 9
chr1_-_173957316 8.934 NM_033509
Vangl2
vang-like 2 (van gogh, Drosophila)
chr6_-_49164469 8.722 Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr13_-_97440734 8.654 NM_008255
Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr4_+_48598013 8.634 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_+_125935441 8.624 NM_023279
Tubb3
tubulin, beta 3
chr11_-_106021399 8.576 NM_172397
Limd2
LIM domain containing 2
chr5_-_135028197 8.530 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr9_-_110526866 8.465 NM_026012
Nradd
neurotrophin receptor associated death domain
chr1_-_135975681 8.305 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr7_+_148401781 8.303 Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr7_-_139508857 8.253 Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr7_+_25292105 8.245 NM_146183
Zfp428
zinc finger protein 428
chr6_-_82724366 8.242 NM_013820
Hk2
hexokinase 2
chr7_+_148401731 8.145 NM_025886
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr1_+_174412343 8.082 NM_001145800
NM_033608
Igsf9

immunoglobulin superfamily, member 9

chr3_-_83844042 8.072 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr6_-_31513817 7.879 NM_013723
Podxl
podocalyxin-like
chr15_-_95358674 7.814 Nell2
NEL-like 2 (chicken)
chr12_+_82127791 7.812 NM_001146217
NM_022316
Smoc1

SPARC related modular calcium binding 1

chr5_+_120881778 7.766 NM_008499
Lhx5
LIM homeobox protein 5
chr5_+_103854200 7.599 NM_011204
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr6_-_86619001 7.507 NM_010751
Mxd1
MAX dimerization protein 1
chr18_-_43552694 7.476 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr8_-_8661238 7.387 Efnb2
ephrin B2
chr6_-_83071206 7.324 Wbp1
WW domain binding protein 1
chr8_-_48373564 7.310 Stox2
storkhead box 2
chr19_+_4756524 7.262 NM_025717
Rbm4b
RNA binding motif protein 4B
chrX_+_104115963 7.236 NM_175271
Lpar4
lysophosphatidic acid receptor 4
chr3_-_68848588 7.090 Trim59
tripartite motif-containing 59
chr2_+_91366928 6.982 Ckap5
cytoskeleton associated protein 5
chr14_+_59820284 6.946 Rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr7_+_120657336 6.906 NM_026143
NM_027379
Far1

fatty acyl CoA reductase 1

chr12_-_36883307 6.839 NM_025840
Bzw2
basic leucine zipper and W2 domains 2
chr6_-_6167113 6.834 NM_001177572
NM_015829
Slc25a13

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13

chr18_-_34166105 6.822 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr3_-_108525202 6.754 NM_029522
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr5_+_147042806 6.752 Cdk8
cyclin-dependent kinase 8
chr9_+_72655019 6.731 NM_175485
Prtg
protogenin homolog (Gallus gallus)
chr4_-_109960078 6.589 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_+_112776424 6.484 Eif5
eukaryotic translation initiation factor 5
chr5_-_149864518 6.482 NM_010439
Hmgb1
high mobility group box 1
chr5_+_28492235 6.463 NM_010134
En2
engrailed 2
chr1_+_134942609 6.450 Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr4_+_13670425 6.449 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_22415277 6.435 NM_008899
Pou3f2
POU domain, class 3, transcription factor 2
chr14_+_73637697 6.397 NM_175116
Lpar6
lysophosphatidic acid receptor 6
chr7_+_88005861 6.374 Zscan2
zinc finger and SCAN domain containing 2
chr9_-_36954842 6.372 NM_001029838
Pknox2
Pbx/knotted 1 homeobox 2
chr4_-_6917964 6.275 Tox
thymocyte selection-associated high mobility group box
chr4_+_122673318 6.220 NM_008506
Mycl1
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr11_+_23978029 6.163 NM_001159289
NM_016707
Bcl11a

B-cell CLL/lymphoma 11A (zinc finger protein)

chr13_-_117099629 6.153 NM_021459
Isl1
ISL1 transcription factor, LIM/homeodomain
chr9_-_99776467 6.115 NM_011440
Sox14
SRY-box containing gene 14
chr2_-_153067043 6.082 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr12_+_53800369 6.055 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr11_+_68505616 6.053 Myh10
myosin, heavy polypeptide 10, non-muscle
chr3_+_145541951 6.028


chr18_-_61867246 6.003 NM_172832
Pcyox1l
prenylcysteine oxidase 1 like
chr7_-_139508762 5.965 NM_029935
Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr14_+_67852128 5.935 NM_010095
Ebf2
early B-cell factor 2
chr9_+_55388955 5.891 NM_027397
Isl2
insulin related protein 2 (islet 2)
chr12_-_40763924 5.891 NM_007487
Arl4a
ADP-ribosylation factor-like 4A
chr4_-_77857594 5.889 Ptprd
protein tyrosine phosphatase, receptor type, D
chr11_-_107655777 5.883 NM_019431
Cacng4
calcium channel, voltage-dependent, gamma subunit 4
chr8_-_67212325 5.852 NM_025436
Sc4mol
sterol-C4-methyl oxidase-like
chr1_-_173957407 5.841 Vangl2
vang-like 2 (van gogh, Drosophila)
chr14_+_51564176 5.749 Pnp
purine-nucleoside phosphorylase
chr11_-_51420336 5.734 NM_001048061
NM_010448
Hnrnpab

heterogeneous nuclear ribonucleoprotein A/B

chr2_-_136942066 5.723 NM_013822
Jag1
jagged 1
chr4_+_100449274 5.719 NM_198037
Cachd1
cache domain containing 1
chr1_+_62749850 5.686 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr10_+_43298969 5.676 NM_009846
Cd24a
CD24a antigen
chr5_-_150438856 5.662 NM_013559
Hsph1
heat shock 105kDa/110kDa protein 1
chrX_+_96331434 5.646 NM_010110
Efnb1
ephrin B1
chr17_-_35975148 5.640 NM_011655
Tubb5
tubulin, beta 5
chr13_-_104124527 5.628 NM_175171
Mast4
microtubule associated serine/threonine kinase family member 4
chr8_+_108939247 5.552 Zfp90
zinc finger protein 90
chr6_+_17015159 5.522 Tes
testis derived transcript
chr13_-_34222209 5.491 NM_023716
Tubb2b
tubulin, beta 2B
chr12_+_30213224 5.486 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr11_-_6344354 5.460 H2afv
H2A histone family, member V
chr5_+_48374328 5.453 NM_178804
Slit2
slit homolog 2 (Drosophila)
chr2_+_44966657 5.452 NM_001177394
Gm13476
predicted gene 13476
chr9_+_40609317 5.447 NM_031165
Hspa8
heat shock protein 8
chr11_-_113613040 5.430 NM_001163346
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr13_+_88961161 5.412 Edil3
EGF-like repeats and discoidin I-like domains 3
chr2_-_37558818 5.411 Strbp
spermatid perinuclear RNA binding protein
chr12_-_36769054 5.407 NM_025359
Tspan13
tetraspanin 13
chr5_-_23536487 5.397 NM_053090
Fam126a
family with sequence similarity 126, member A
chr16_+_18392675 5.395 Arvcf
armadillo repeat gene deleted in velo-cardio-facial syndrome
chr12_-_56087322 5.367 NM_013815
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr17_+_36003000 5.367 NM_001146710
2310014H01Rik
RIKEN cDNA 2310014H01 gene
chr3_-_108525060 5.364 Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr2_+_152561983 5.356 NM_010495
Id1
inhibitor of DNA binding 1
chr19_-_15999377 5.334 NM_177420
Psat1
phosphoserine aminotransferase 1
chr18_+_36720238 5.308 NM_175375
Ankhd1
ankyrin repeat and KH domain containing 1
chr8_+_72346327 5.306 NM_020028
Lpar2
lysophosphatidic acid receptor 2
chr10_+_7387285 5.240 NM_145706
Nup43
nucleoporin 43
chr15_-_95358989 5.232 Nell2
NEL-like 2 (chicken)
chr10_-_61246611 5.232 NM_207000
H2afy2
H2A histone family, member Y2
chr1_+_131170053 5.209 Thsd7b
thrombospondin, type I, domain containing 7B
chr17_-_56970332 5.184 NM_009056
NM_027787
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr11_-_77707282 5.168 NM_008952
Pipox
pipecolic acid oxidase
chr4_+_118781405 5.160 Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr17_-_36046961 5.146 NM_001142744
NM_001142745
NM_028476
Atat1


alpha tubulin acetyltransferase 1


chr11_-_69373555 5.112 Efnb3
ephrin B3
chr4_-_118846774 5.100 Zfp691
zinc finger protein 691
chr2_+_164595415 5.088 NM_026785
Ube2c
ubiquitin-conjugating enzyme E2C
chr2_+_109120894 5.074 NM_139303
Kif18a
kinesin family member 18A
chr5_-_115750940 5.016 Dynll1
dynein light chain LC8-type 1
chr12_+_112776539 5.008 Eif5
eukaryotic translation initiation factor 5
chr4_-_22415444 4.999 Pou3f2
POU domain, class 3, transcription factor 2
chr3_-_68848657 4.970 NM_025863
Trim59
tripartite motif-containing 59
chr12_-_21422781 4.963 Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr9_-_115219553 4.963 Stt3b
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr13_+_51942043 4.961 NM_011817
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chrX_+_54307050 4.955 Htatsf1
HIV TAT specific factor 1
chr1_-_33871349 4.938 Zfp451
zinc finger protein 451
chr3_+_66023884 4.926 Ptx3
pentraxin related gene
chr16_+_38089086 4.920 NM_019827
Gsk3b
glycogen synthase kinase 3 beta
chr7_-_112936063 4.911 NM_001162943
Dchs1
dachsous 1 (Drosophila)
chr12_+_17273358 4.896 NM_027959
Pdia6
protein disulfide isomerase associated 6
chr14_+_121310342 4.881 NM_023579
Ipo5
importin 5
chr7_-_137409721 4.846 Fgfr2
fibroblast growth factor receptor 2
chr2_-_39046224 4.833 NM_178778
Scai
suppressor of cancer cell invasion
chr1_+_70772288 4.833 NM_177164
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr4_+_128404814 4.818 NM_001195083
Phc2
polyhomeotic-like 2 (Drosophila)
chr6_+_37820779 4.814 NM_145076
Trim24
tripartite motif-containing 24
chrX_-_137077133 4.813 Tsc22d3
TSC22 domain family, member 3
chrX_+_50265390 4.796 NM_027642
Phf6
PHD finger protein 6
chr2_-_92232506 4.792 Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr11_-_3271326 4.791 Limk2
LIM motif-containing protein kinase 2
chr3_+_34548916 4.773 NM_011443
Sox2
SRY-box containing gene 2
chr3_+_55046579 4.770 Dclk1
doublecortin-like kinase 1
chr11_+_86922732 4.767 NM_025377
Fam33a
family with sequence similarity 33, member A
chr11_-_96805294 4.736 NM_134021
Pnpo
pyridoxine 5'-phosphate oxidase
chr6_+_5340417 4.728 Asb4
ankyrin repeat and SOCS box-containing 4
chr15_-_83555335 4.727 NM_022723
Scube1
signal peptide, CUB domain, EGF-like 1
chr2_-_72818502 4.697 NM_001018042
Sp3
trans-acting transcription factor 3
chrX_+_110411860 4.693 NM_001142570
NM_033605
Dach2

dachshund 2 (Drosophila)

chr10_+_57206184 4.691 NM_008297
Hsf2
heat shock factor 2
chr4_+_47366162 4.684 NM_009370
Tgfbr1
transforming growth factor, beta receptor I
chr11_+_68505576 4.675 Myh10
myosin, heavy polypeptide 10, non-muscle
chr17_-_35975075 4.668 Tubb5
tubulin, beta 5
chr12_+_96930429 4.632 NM_201518
Flrt2
fibronectin leucine rich transmembrane protein 2
chr14_+_73542347 4.628 Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_90483392 4.626 NM_033327
Zfp423
zinc finger protein 423
chr11_+_121098532 4.626 NM_026272
Narf
nuclear prelamin A recognition factor
chr7_+_103358652 4.621 Odz4
odd Oz/ten-m homolog 4 (Drosophila)
chr14_+_76245136 4.579 Tpt1
tumor protein, translationally-controlled 1
chr3_+_145784635 4.578 NM_134160
Mcoln3
mucolipin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.18 4.14e-24 GO:0010468 regulation of gene expression
1.78 9.39e-23 GO:0044260 cellular macromolecule metabolic process
2.23 1.18e-22 GO:0051252 regulation of RNA metabolic process
1.94 1.50e-21 GO:0060255 regulation of macromolecule metabolic process
2.21 1.92e-21 GO:0006355 regulation of transcription, DNA-dependent
2.14 4.59e-21 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.90 1.32e-20 GO:0034641 cellular nitrogen compound metabolic process
1.88 1.43e-20 GO:0006807 nitrogen compound metabolic process
1.96 1.59e-20 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09 8.15e-20 GO:0010556 regulation of macromolecule biosynthetic process
2.05 8.88e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.06 9.50e-20 GO:0090304 nucleic acid metabolic process
1.57 1.32e-19 GO:0044237 cellular metabolic process
2.03 3.01e-19 GO:0051171 regulation of nitrogen compound metabolic process
1.86 3.97e-19 GO:0031323 regulation of cellular metabolic process
2.73 1.53e-18 GO:0007399 nervous system development
1.77 4.60e-18 GO:0019222 regulation of metabolic process
1.84 4.63e-18 GO:0080090 regulation of primary metabolic process
2.10 5.83e-18 GO:0016070 RNA metabolic process
1.99 7.35e-18 GO:0031326 regulation of cellular biosynthetic process
1.97 3.01e-17 GO:0009889 regulation of biosynthetic process
1.63 5.89e-17 GO:0043170 macromolecule metabolic process
1.52 2.13e-16 GO:0044238 primary metabolic process
2.02 4.85e-16 GO:0034645 cellular macromolecule biosynthetic process
2.24 9.00e-16 GO:0006351 transcription, DNA-dependent
2.24 1.05e-15 GO:0032774 RNA biosynthetic process
2.01 1.11e-15 GO:0009059 macromolecule biosynthetic process
1.85 3.43e-15 GO:0044249 cellular biosynthetic process
1.82 7.72e-15 GO:0009058 biosynthetic process
1.94 1.07e-14 GO:0010467 gene expression
1.91 1.21e-14 GO:0048856 anatomical structure development
1.85 1.43e-14 GO:0007275 multicellular organismal development
1.81 1.92e-14 GO:0032502 developmental process
2.06 9.69e-14 GO:0048869 cellular developmental process
2.08 1.15e-13 GO:0030154 cell differentiation
1.94 2.15e-13 GO:0048731 system development
2.70 8.34e-12 GO:0022008 neurogenesis
1.40 1.45e-11 GO:0008152 metabolic process
2.73 2.83e-11 GO:0048699 generation of neurons
1.86 1.81e-09 GO:0071842 cellular component organization at cellular level
1.35 1.98e-09 GO:0050794 regulation of cellular process
1.80 8.32e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.32 1.34e-08 GO:0050789 regulation of biological process
2.04 2.01e-08 GO:0006996 organelle organization
2.86 2.02e-08 GO:0030182 neuron differentiation
1.21 3.17e-08 GO:0009987 cellular process
1.79 4.18e-08 GO:0048523 negative regulation of cellular process
2.37 6.50e-08 GO:0048468 cell development
3.30 1.16e-07 GO:0007420 brain development
1.29 1.29e-07 GO:0065007 biological regulation
1.65 1.39e-07 GO:0016043 cellular component organization
2.96 1.60e-07 GO:0007417 central nervous system development
1.62 3.21e-07 GO:0071840 cellular component organization or biogenesis
1.62 1.00e-06 GO:0048518 positive regulation of biological process
3.75 1.77e-06 GO:0030900 forebrain development
1.67 2.46e-06 GO:0048519 negative regulation of biological process
1.80 2.91e-06 GO:0048513 organ development
2.33 1.38e-05 GO:0010629 negative regulation of gene expression
2.29 2.58e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.60 2.69e-05 GO:0048522 positive regulation of cellular process
3.03 3.23e-05 GO:0045596 negative regulation of cell differentiation
1.85 4.65e-05 GO:0009653 anatomical structure morphogenesis
2.52 5.93e-05 GO:0043009 chordate embryonic development
3.13 6.71e-05 GO:0045664 regulation of neuron differentiation
2.48 9.00e-05 GO:0009792 embryo development ending in birth or egg hatching
1.98 9.00e-05 GO:0050793 regulation of developmental process
2.20 9.94e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
2.17 1.21e-04 GO:0031327 negative regulation of cellular biosynthetic process
2.71 1.31e-04 GO:0051093 negative regulation of developmental process
2.30 1.47e-04 GO:0045892 negative regulation of transcription, DNA-dependent
4.53 1.52e-04 GO:0021915 neural tube development
4.75 1.71e-04 GO:0021953 central nervous system neuron differentiation
1.98 1.75e-04 GO:0010605 negative regulation of macromolecule metabolic process
2.12 1.92e-04 GO:0045595 regulation of cell differentiation
2.27 2.33e-04 GO:0051253 negative regulation of RNA metabolic process
2.07 2.46e-04 GO:0051128 regulation of cellular component organization
2.12 2.65e-04 GO:0009890 negative regulation of biosynthetic process
2.81 3.11e-04 GO:0031175 neuron projection development
2.03 3.30e-04 GO:2000026 regulation of multicellular organismal development
2.56 3.51e-04 GO:0048666 neuron development
2.06 3.84e-04 GO:0009790 embryo development
2.77 4.13e-04 GO:0050767 regulation of neurogenesis
2.52 5.08e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.63 5.76e-04 GO:0051960 regulation of nervous system development
2.12 1.05e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.92 1.12e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.33 1.34e-03 GO:0051276 chromosome organization
1.86 1.46e-03 GO:0009892 negative regulation of metabolic process
2.11 1.57e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.41 2.24e-03 GO:0048598 embryonic morphogenesis
2.33 2.54e-03 GO:0032989 cellular component morphogenesis
1.54 2.92e-03 GO:0044267 cellular protein metabolic process
1.87 3.15e-03 GO:0031324 negative regulation of cellular metabolic process
2.44 3.20e-03 GO:0060284 regulation of cell development
5.91 3.49e-03 GO:0045665 negative regulation of neuron differentiation
2.64 4.02e-03 GO:0032990 cell part morphogenesis
2.34 4.33e-03 GO:0007010 cytoskeleton organization
2.27 4.73e-03 GO:0030030 cell projection organization
2.34 6.29e-03 GO:0000902 cell morphogenesis
2.96 6.75e-03 GO:0007409 axonogenesis
2.60 8.09e-03 GO:0048858 cell projection morphogenesis
2.59 8.62e-03 GO:0000904 cell morphogenesis involved in differentiation
2.82 9.93e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.35 1.07e-02 GO:0060429 epithelium development
1.70 1.11e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.71 1.29e-02 GO:0003002 regionalization
2.64 1.32e-02 GO:0002009 morphogenesis of an epithelium
5.71 1.45e-02 GO:0019827 stem cell maintenance
2.37 1.73e-02 GO:0006325 chromatin organization
1.91 1.95e-02 GO:0051254 positive regulation of RNA metabolic process
2.21 2.03e-02 GO:0051726 regulation of cell cycle
2.70 2.15e-02 GO:0048812 neuron projection morphogenesis
2.33 2.39e-02 GO:0000278 mitotic cell cycle
1.56 2.55e-02 GO:0043412 macromolecule modification
4.47 2.57e-02 GO:0048762 mesenchymal cell differentiation
1.70 2.70e-02 GO:0009966 regulation of signal transduction
2.44 2.71e-02 GO:0035295 tube development
1.90 2.73e-02 GO:0045893 positive regulation of transcription, DNA-dependent
5.27 3.03e-02 GO:0048864 stem cell development
1.86 3.07e-02 GO:0007049 cell cycle
1.82 3.08e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.85 3.11e-02 GO:0010628 positive regulation of gene expression
2.85 3.23e-02 GO:0044087 regulation of cellular component biogenesis
4.73 3.39e-02 GO:0048863 stem cell differentiation
1.57 3.47e-02 GO:0006464 protein modification process
2.31 3.85e-02 GO:0007389 pattern specification process
7.83 3.87e-02 GO:0030901 midbrain development
4.66 3.94e-02 GO:0014031 mesenchymal cell development
2.02 4.44e-02 GO:0022402 cell cycle process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.94 7.87e-38 GO:0005634 nucleus
1.41 2.47e-30 GO:0005622 intracellular
1.42 5.85e-30 GO:0044424 intracellular part
1.49 2.64e-29 GO:0043229 intracellular organelle
1.49 5.90e-29 GO:0043226 organelle
1.49 7.68e-24 GO:0043231 intracellular membrane-bounded organelle
1.49 1.24e-23 GO:0043227 membrane-bounded organelle
1.92 1.45e-09 GO:0044428 nuclear part
1.53 4.48e-09 GO:0044446 intracellular organelle part
1.51 1.59e-08 GO:0044422 organelle part
2.63 6.11e-08 GO:0015630 microtubule cytoskeleton
1.85 6.71e-08 GO:0031974 membrane-enclosed lumen
1.69 6.76e-08 GO:0043228 non-membrane-bounded organelle
1.69 6.76e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.84 1.73e-07 GO:0070013 intracellular organelle lumen
1.84 1.92e-07 GO:0043233 organelle lumen
1.13 1.92e-07 GO:0005623 cell
1.13 1.92e-07 GO:0044464 cell part
1.90 3.11e-07 GO:0031981 nuclear lumen
1.28 6.16e-07 GO:0005737 cytoplasm
1.79 1.66e-05 GO:0005856 cytoskeleton
1.98 5.48e-05 GO:0044430 cytoskeletal part
1.69 3.85e-04 GO:0005829 cytosol
1.42 5.33e-04 GO:0032991 macromolecular complex
1.82 8.47e-04 GO:0005654 nucleoplasm
1.44 1.49e-03 GO:0043234 protein complex
5.59 2.51e-03 GO:0030496 midbody
2.65 2.75e-03 GO:0005874 microtubule
2.14 7.72e-03 GO:0005694 chromosome
2.18 9.14e-03 GO:0044427 chromosomal part
9.98 2.46e-02 GO:0000932 cytoplasmic mRNA processing body
3.80 3.91e-02 GO:0016585 chromatin remodeling complex
20.96 4.94e-02 GO:0001740 Barr body

Gene overrepresentation in function category:

enrichment p-value GO term description
1.36 2.67e-21 GO:0005488 binding
2.07 2.50e-20 GO:0003676 nucleic acid binding
2.13 3.39e-14 GO:0003677 DNA binding
1.49 2.72e-12 GO:0005515 protein binding
2.48 3.99e-11 GO:0030528 transcription regulator activity
2.02 1.29e-10 GO:0046914 transition metal ion binding
2.10 6.53e-10 GO:0008270 zinc ion binding
2.28 3.38e-06 GO:0003723 RNA binding
2.22 5.03e-06 GO:0001071 nucleic acid binding transcription factor activity
2.22 5.03e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.95 1.24e-05 GO:0016564 transcription repressor activity
4.77 1.92e-04 GO:0003729 mRNA binding
1.42 4.51e-04 GO:0046872 metal ion binding
1.41 7.32e-04 GO:0043167 ion binding
2.08 7.85e-04 GO:0043565 sequence-specific DNA binding
1.40 9.22e-04 GO:0043169 cation binding
2.79 1.61e-03 GO:0019901 protein kinase binding
2.12 3.57e-03 GO:0019904 protein domain specific binding
2.52 4.47e-03 GO:0019900 kinase binding
1.49 5.65e-03 GO:0000166 nucleotide binding
3.65 5.94e-03 GO:0015631 tubulin binding
1.80 1.06e-02 GO:0019899 enzyme binding
7.99 2.78e-02 GO:0003730 mRNA 3'-UTR binding