Motif ID: SOX2.p2

Z-value: 3.098

Transcription factors associated with SOX2.p2:

NameEntrezDescription
Sox2 20674 SRY-box containing gene 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Sox2chr3_+_34549057-0.591.7e-04Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr7_-_56892061 43.525 NM_001005232
Dbx1
developing brain homeobox 1
chr1_-_42749940 35.230 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr8_+_46593141 30.431 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr1_-_140739020 22.433 NM_001025565
NM_001042577
Lhx9

LIM homeobox protein 9

chr10_+_17516024 21.462 NM_138628
Txlnb
taxilin beta
chr2_-_65405546 21.046 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_+_43298969 20.984 NM_009846
Cd24a
CD24a antigen
chr6_-_12699189 20.610 NM_001164805
Thsd7a
thrombospondin, type I, domain containing 7A
chr18_-_46372017 19.849 NM_178872
Trim36
tripartite motif-containing 36
chr1_-_12980994 19.743 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr12_+_30219982 19.268 Myt1l
myelin transcription factor 1-like
chrX_-_149078963 17.236 Shroom2
shroom family member 2
chr10_+_119256444 16.614 NM_028736
NM_130891
Grip1

glutamate receptor interacting protein 1

chr5_+_48374328 15.339 NM_178804
Slit2
slit homolog 2 (Drosophila)
chr18_-_43552694 15.076 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr2_+_181498036 14.389 NM_001171615
Myt1
myelin transcription factor 1
chrX_+_106290703 14.141 NM_019989
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr11_+_93905557 13.868 Spag9
sperm associated antigen 9
chr7_-_91827857 13.825 NM_022985
Zfand6
zinc finger, AN1-type domain 6
chr4_+_109015660 13.713 NM_001159964
Eps15
epidermal growth factor receptor pathway substrate 15
chr12_+_30213224 13.331 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr2_-_59963586 13.071 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr5_-_135028197 12.853 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr10_+_101621491 12.428 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chrX_+_139952975 12.303 NM_001195048
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr12_-_36769054 11.206 NM_025359
Tspan13
tetraspanin 13
chr4_+_129190877 11.145 Marcksl1
MARCKS-like 1
chr4_-_109960078 10.804 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_+_129190872 10.602 Marcksl1
MARCKS-like 1
chr8_+_63703064 10.541 Sh3rf1
SH3 domain containing ring finger 1
chr4_+_48598013 10.353 NM_021436
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_-_107734481 10.058 NM_026672
Gstm7
glutathione S-transferase, mu 7
chr3_-_66100663 9.919 NM_145820
Veph1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr6_-_138371302 9.858 Lmo3
LIM domain only 3
chr10_+_28863801 9.767 NM_026138
6330407J23Rik
RIKEN cDNA 6330407J23 gene
chrX_+_130829929 9.662 Tmem35
transmembrane protein 35
chr2_+_157385835 9.601 NM_010923
NM_180960
Nnat

neuronatin

chr5_+_143722032 9.577 NM_007984
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr3_-_122322556 9.519 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr19_-_19185685 9.424 NM_001043354
Rorb
RAR-related orphan receptor beta
chr2_+_61642509 9.351 NM_009322
Tbr1
T-box brain gene 1
chr8_-_86760940 9.333 NM_172503
Zswim4
zinc finger, SWIM domain containing 4
chr13_-_56353523 9.183 NM_010896
Neurog1
neurogenin 1
chr14_-_20796411 8.881 NM_001038637
NM_010315
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr2_-_73613381 8.737 NM_001113246
NM_001166603
Chn1

chimerin (chimaerin) 1

chr4_+_13670582 8.664 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_17125198 8.606 NM_183287
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr18_+_59222034 8.572 NM_001167925
NM_173759
A730017C20Rik

RIKEN cDNA A730017C20 gene

chr14_-_20796199 8.551 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr10_+_68996455 8.479 NM_146005
NM_170688
NM_170689
NM_170690
NM_170728
NM_170729
NM_170730
Ank3






ankyrin 3, epithelial






chr17_-_35975148 8.360 NM_011655
Tubb5
tubulin, beta 5
chr5_+_89012547 8.319 Rufy3
RUN and FYVE domain containing 3
chrX_-_140367467 8.228 NM_001110222
NM_001110223
NM_001110224
NM_010025
Dcx



doublecortin



chr12_-_32398730 8.219 NM_175191
Gpr22
G protein-coupled receptor 22
chr1_-_195196423 8.192 NM_144817
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr3_+_127336055 8.191 NM_009718
Neurog2
neurogenin 2
chr3_+_53959956 8.165 NM_016984
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr17_+_17539832 8.069 Lix1
limb expression 1 homolog (chicken)
chr3_+_94282235 8.061 Celf3
VCUGBP, Elav-like family member 3
chr19_-_46114019 8.060 NM_010697
Ldb1
LIM domain binding 1
chr5_-_92512683 8.043 NM_001080795
NM_011816
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr10_+_79612410 8.000 Midn
midnolin
chr10_+_57206184 7.965 NM_008297
Hsf2
heat shock factor 2
chr2_+_37372112 7.912 NM_177383
Gpr21
G protein-coupled receptor 21
chr4_-_20705698 7.850 NM_172987
Nkain3
Na+/K+ transporting ATPase interacting 3
chr1_+_19198994 7.789 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr16_-_44558929 7.768 NM_172506
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr18_-_75120759 7.759 NM_010720
Lipg
lipase, endothelial
chr18_-_16966954 7.706 Cdh2
cadherin 2
chr14_-_109313298 7.674 Slitrk1
SLIT and NTRK-like family, member 1
chr19_+_4756524 7.660 NM_025717
Rbm4b
RNA binding motif protein 4B
chr2_-_56967331 7.631 NM_013613
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr5_+_67067477 7.539 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_+_93905443 7.477 Spag9
sperm associated antigen 9
chr4_-_91042997 7.443 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_+_17015159 7.292 Tes
testis derived transcript
chr3_+_101814059 7.221 NM_178777
Nhlh2
nescient helix loop helix 2
chr3_-_143865162 7.168 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr13_-_54789064 7.161 Rnf44
ring finger protein 44
chr3_-_83844042 7.123 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr5_+_13399492 7.074 Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_77857594 7.054 Ptprd
protein tyrosine phosphatase, receptor type, D
chr4_-_6917628 6.919 NM_145711
Tox
thymocyte selection-associated high mobility group box
chr10_-_26095736 6.771 L3mbtl3
l(3)mbt-like 3 (Drosophila)
chr12_+_53800369 6.734 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_59963796 6.628 NM_001001182
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr15_-_26825266 6.622 NM_176959
Fbxl7
F-box and leucine-rich repeat protein 7
chr12_+_3365147 6.620 Kif3c
kinesin family member 3C
chr12_+_96930429 6.609 NM_201518
Flrt2
fibronectin leucine rich transmembrane protein 2
chr8_+_63702967 6.596 NM_021506
Sh3rf1
SH3 domain containing ring finger 1
chr7_-_111001598 6.589 NM_008221
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr9_+_96159666 6.561 NM_001184710
NM_001184711
Tfdp2

transcription factor Dp 2

chr2_-_165710128 6.516 NM_027230
Zmynd8
zinc finger, MYND-type containing 8
chr6_+_64992584 6.469 NM_007958
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_+_96159123 6.433 NM_001184709
Tfdp2
transcription factor Dp 2
chr7_+_69493148 6.431 NM_010882
Ndn
necdin
chr15_+_98465193 6.426 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr3_+_89019126 6.386 Thbs3
thrombospondin 3
chr9_+_74823917 6.386 NM_153584
BC031353
cDNA sequence BC031353
chr8_-_42140113 6.314 NM_001005864
Mtus1
mitochondrial tumor suppressor 1
chr1_+_9591550 6.302 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr12_+_30219769 6.282 NM_001093776
Myt1l
myelin transcription factor 1-like
chr1_+_155596555 6.267 NM_011882
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr5_-_92566671 6.244


chr9_-_71743854 6.239 Tcf12
transcription factor 12
chr4_-_77857753 6.206 Ptprd
protein tyrosine phosphatase, receptor type, D
chr4_+_13670425 6.178 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_62749850 6.139 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr11_-_95867076 6.106 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr11_+_93905501 6.102 NM_001025428
NM_001025429
NM_001025430
Spag9


sperm associated antigen 9


chr2_-_51004604 6.102 NM_028810
Rnd3
Rho family GTPase 3
chr4_+_111087610 6.029 NM_026279
Bend5
BEN domain containing 5
chr7_-_112936063 6.015 NM_001162943
Dchs1
dachsous 1 (Drosophila)
chr16_+_17070249 6.005 NM_023249
Ypel1
yippee-like 1 (Drosophila)
chr18_+_65048630 5.996 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_+_14976877 5.973 NM_029466
Arl5b
ADP-ribosylation factor-like 5B
chr5_+_89012600 5.919 Rufy3
RUN and FYVE domain containing 3
chr4_-_155571450 5.868 Agrn
agrin
chr7_-_134758707 5.846 Zfp629
zinc finger protein 629
chr5_+_19413335 5.826 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr18_-_33623527 5.814 D0H4S114
DNA segment, human D4S114
chrX_-_103124651 5.773 NM_009530
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chrX_+_104115963 5.768 NM_175271
Lpar4
lysophosphatidic acid receptor 4
chr5_+_111846284 5.734 Mn1
meningioma 1
chr9_-_117161564 5.714 NM_001172122
NM_001172123
NM_001172124
NM_001172126
NM_178660
Rbms3




RNA binding motif, single stranded interacting protein




chr1_-_135817945 5.702 NM_054077
Prelp
proline arginine-rich end leucine-rich repeat
chr5_+_36236113 5.701 Afap1
actin filament associated protein 1
chr7_+_134376574 5.654 Zfp553
zinc finger protein 553
chr12_-_14158843 5.644 NM_029007
Fam84a
family with sequence similarity 84, member A
chr13_-_55589377 5.633 NM_001177371
NM_001177372
NM_019813
Dbn1


drebrin 1


chr6_-_31513817 5.549 NM_013723
Podxl
podocalyxin-like
chr9_-_49606959 5.544 Ncam1
neural cell adhesion molecule 1
chr1_+_59969845 5.543 NM_001037725
Fam117b
family with sequence similarity 117, member B
chr15_-_76983985 5.529 NM_001110828
NM_001110829
NM_001110830
Rbfox2


RNA binding protein, fox-1 homolog (C. elegans) 2


chr9_+_55388955 5.512 NM_027397
Isl2
insulin related protein 2 (islet 2)
chr15_-_98783909 5.511 NM_011653
Tuba1a
tubulin, alpha 1A
chr16_+_19760300 5.460 NM_001159407
NM_001159408
NM_054052
B3gnt5


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5


chr6_+_17015148 5.432 NM_207176
Tes
testis derived transcript
chr5_+_28492235 5.417 NM_010134
En2
engrailed 2
chr10_-_25798768 5.374 NM_029881
Tmem200a
transmembrane protein 200A
chr10_-_61246611 5.344 NM_207000
H2afy2
H2A histone family, member Y2
chr1_-_33871349 5.339 Zfp451
zinc finger protein 451
chr13_+_88961161 5.326 Edil3
EGF-like repeats and discoidin I-like domains 3
chr6_+_64992810 5.301 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_84024766 5.296 NM_030706
Trim2
tripartite motif-containing 2
chr7_+_90015842 5.215 NM_175366
Mex3b
mex3 homolog B (C. elegans)
chr3_+_5218545 5.163 NM_030708
Zfhx4
zinc finger homeodomain 4
chr16_+_93608058 5.157 NM_007620
Cbr1
carbonyl reductase 1
chrX_+_140098931 5.157


chr5_+_67067497 5.150 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chrY_-_582062 5.079 NM_009484
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr7_-_91558468 5.072 NM_007488
Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr5_-_103640272 5.042 NM_001081567
NM_009158
Mapk10

mitogen-activated protein kinase 10

chr2_+_65683823 4.925 NM_153409
NM_178634
Csrnp3

cysteine-serine-rich nuclear protein 3

chr8_-_64238879 4.916 Palld
palladin, cytoskeletal associated protein
chr19_-_47036782 4.877 NM_029810
Nt5c2
5'-nucleotidase, cytosolic II
chr10_+_27794664 4.865 Ptprk
protein tyrosine phosphatase, receptor type, K
chr1_-_97564064 4.860 St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_-_15822792 4.847 Trib2
tribbles homolog 2 (Drosophila)
chr5_-_115750940 4.833 Dynll1
dynein light chain LC8-type 1
chr10_-_93498449 4.831 Vezt
vezatin, adherens junctions transmembrane protein
chr3_-_95032039 4.826 Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_+_78301923 4.806 NM_001025192
NM_009988
Cxadr

coxsackie virus and adenovirus receptor

chr1_+_139795165 4.763 A630083H20Rik
RIKEN cDNA A630083H20 gene
chr13_-_111070344 4.738 Rab3c
RAB3C, member RAS oncogene family
chr5_+_31014229 4.736 NM_023047
Dpysl5
dihydropyrimidinase-like 5
chr8_-_87461251 4.727 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr3_+_121129396 4.711 NM_028044
Cnn3
calponin 3, acidic
chr7_+_103358652 4.688 Odz4
odd Oz/ten-m homolog 4 (Drosophila)
chr3_+_7503409 4.671 NM_173181
Fam164a
family with sequence similarity 164, member A
chr10_+_17443024 4.627 NM_010828
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr7_+_106614513 4.602 NM_028145
Klhl35
kelch-like 35 (Drosophila)
chr1_-_128634766 4.572 Nckap5
NCK-associated protein 5
chr14_-_20796255 4.571 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr15_-_95358674 4.568 Nell2
NEL-like 2 (chicken)
chr10_-_93498482 4.529 Vezt
vezatin, adherens junctions transmembrane protein
chr6_+_64992861 4.513 Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_-_93498488 4.512 NM_172538
Vezt
vezatin, adherens junctions transmembrane protein
chrX_+_35542969 4.509 NM_001079513
NM_020256
Zbtb33

zinc finger and BTB domain containing 33

chr9_-_49607017 4.479 Ncam1
neural cell adhesion molecule 1
chr11_+_117193732 4.468


chr5_+_89012537 4.449 Rufy3
RUN and FYVE domain containing 3
chr18_-_15309939 4.417 NM_134112
Kctd1
potassium channel tetramerisation domain containing 1
chr4_+_11083585 4.358 NM_021897
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr4_+_122673318 4.314 NM_008506
Mycl1
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr5_+_37637027 4.304 NM_007765
Crmp1
collapsin response mediator protein 1
chr3_+_8509479 4.280 NM_025285
Stmn2
stathmin-like 2
chr13_-_111070225 4.277 Rab3c
RAB3C, member RAS oncogene family
chr6_+_71657791 4.275 NM_178608
Reep1
receptor accessory protein 1
chr6_+_15135505 4.273 NM_212435
Foxp2
forkhead box P2
chr1_-_167865030 4.212 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chr1_-_135817867 4.199


chrX_-_131285919 4.199 NM_001007578
Armcx6
armadillo repeat containing, X-linked 6
chr11_-_107655777 4.168 NM_019431
Cacng4
calcium channel, voltage-dependent, gamma subunit 4
chr5_+_73398142 4.166 NM_173403
Slc10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr17_-_35975075 4.161 Tubb5
tubulin, beta 5
chr11_+_23978110 4.152 Bcl11a
B-cell CLL/lymphoma 11A (zinc finger protein)
chr9_+_61220162 4.136 NM_001083927
NM_001083928
NM_009389
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr13_-_40829082 4.125 NM_011547
Tcfap2a
transcription factor AP-2, alpha
chr5_+_34326081 4.123 NM_001033458
Gm1673
predicted gene 1673

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
3.02 1.04e-22 GO:0007399 nervous system development
3.47 3.09e-20 GO:0048699 generation of neurons
2.13 3.25e-20 GO:0010468 regulation of gene expression
3.37 3.42e-20 GO:0022008 neurogenesis
2.21 5.76e-20 GO:0051252 regulation of RNA metabolic process
2.14 4.24e-19 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.19 1.08e-18 GO:0006355 regulation of transcription, DNA-dependent
2.10 2.27e-18 GO:0010556 regulation of macromolecule biosynthetic process
3.77 1.46e-16 GO:0030182 neuron differentiation
2.01 1.57e-16 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.00 1.87e-16 GO:0051171 regulation of nitrogen compound metabolic process
1.85 6.06e-16 GO:0060255 regulation of macromolecule metabolic process
1.98 7.48e-16 GO:0031326 regulation of cellular biosynthetic process
4.58 1.50e-15 GO:0031175 neuron projection development
1.92 2.02e-15 GO:0007275 multicellular organismal development
4.07 2.26e-15 GO:0048666 neuron development
1.96 2.67e-15 GO:0009889 regulation of biosynthetic process
1.83 3.86e-14 GO:0032502 developmental process
5.33 3.88e-14 GO:0007409 axonogenesis
1.77 6.01e-14 GO:0031323 regulation of cellular metabolic process
2.00 6.23e-14 GO:0048731 system development
4.98 1.55e-13 GO:0048667 cell morphogenesis involved in neuron differentiation
2.20 2.17e-13 GO:0006351 transcription, DNA-dependent
1.91 2.47e-13 GO:0048856 anatomical structure development
2.19 2.49e-13 GO:0032774 RNA biosynthetic process
2.11 2.96e-13 GO:0030154 cell differentiation
1.75 6.09e-13 GO:0080090 regulation of primary metabolic process
2.06 1.25e-12 GO:0048869 cellular developmental process
2.81 1.30e-12 GO:0048468 cell development
3.51 1.52e-12 GO:0030030 cell projection organization
1.67 2.46e-12 GO:0019222 regulation of metabolic process
4.64 4.30e-12 GO:0048812 neuron projection morphogenesis
4.14 1.86e-11 GO:0048858 cell projection morphogenesis
4.13 2.09e-11 GO:0000904 cell morphogenesis involved in differentiation
1.98 2.69e-11 GO:0071842 cellular component organization at cellular level
1.91 3.28e-11 GO:0016070 RNA metabolic process
4.06 3.69e-11 GO:0032990 cell part morphogenesis
1.89 5.73e-10 GO:0071841 cellular component organization or biogenesis at cellular level
3.34 1.35e-09 GO:0000902 cell morphogenesis
2.18 1.60e-09 GO:0009653 anatomical structure morphogenesis
1.76 4.50e-09 GO:0090304 nucleic acid metabolic process
1.67 7.89e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.84 1.35e-08 GO:0040011 locomotion
3.07 2.62e-08 GO:0032989 cellular component morphogenesis
1.70 3.07e-08 GO:0016043 cellular component organization
1.75 3.39e-08 GO:0010467 gene expression
1.49 7.33e-08 GO:0044260 cellular macromolecule metabolic process
3.08 1.12e-07 GO:0007417 central nervous system development
3.75 1.22e-07 GO:0045664 regulation of neuron differentiation
3.29 1.27e-07 GO:0051960 regulation of nervous system development
5.40 1.69e-07 GO:0007411 axon guidance
1.75 1.88e-07 GO:0034645 cellular macromolecule biosynthetic process
1.73 3.26e-07 GO:0009059 macromolecule biosynthetic process
1.64 4.17e-07 GO:0071840 cellular component organization or biogenesis
3.32 5.25e-07 GO:0007420 brain development
2.32 8.62e-07 GO:2000026 regulation of multicellular organismal development
2.19 1.05e-06 GO:0050793 regulation of developmental process
3.30 1.11e-06 GO:0050767 regulation of neurogenesis
3.05 1.15e-06 GO:0060284 regulation of cell development
2.39 1.31e-06 GO:0045595 regulation of cell differentiation
1.55 1.81e-06 GO:0034641 cellular nitrogen compound metabolic process
1.29 2.01e-06 GO:0050789 regulation of biological process
1.28 2.37e-06 GO:0065007 biological regulation
1.53 2.38e-06 GO:0006807 nitrogen compound metabolic process
2.87 4.12e-06 GO:0006928 cellular component movement
1.30 4.63e-06 GO:0050794 regulation of cellular process
3.01 7.58e-06 GO:0016477 cell migration
2.15 8.49e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.58 4.15e-05 GO:0048518 positive regulation of biological process
1.38 4.35e-05 GO:0043170 macromolecule metabolic process
2.77 4.39e-05 GO:0048870 cell motility
2.77 4.39e-05 GO:0051674 localization of cell
2.14 5.82e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
2.23 7.24e-05 GO:0045893 positive regulation of transcription, DNA-dependent
3.94 7.41e-05 GO:0010975 regulation of neuron projection development
1.67 7.42e-05 GO:0048523 negative regulation of cellular process
3.52 8.63e-05 GO:0030900 forebrain development
2.20 1.18e-04 GO:0051254 positive regulation of RNA metabolic process
2.06 1.36e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.78 1.43e-04 GO:0051093 negative regulation of developmental process
2.99 1.68e-04 GO:0045596 negative regulation of cell differentiation
2.13 2.05e-04 GO:0010628 positive regulation of gene expression
2.02 2.71e-04 GO:0009891 positive regulation of biosynthetic process
3.53 2.76e-04 GO:0031344 regulation of cell projection organization
1.58 3.07e-04 GO:0048522 positive regulation of cellular process
2.34 5.83e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.30 7.75e-04 GO:0044237 cellular metabolic process
2.17 9.89e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.02 1.04e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 1.23e-03 GO:0044249 cellular biosynthetic process
2.24 1.25e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.13 1.30e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.10 1.42e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.77 1.42e-03 GO:0016568 chromatin modification
2.21 1.87e-03 GO:0051253 negative regulation of RNA metabolic process
2.98 2.07e-03 GO:0006935 chemotaxis
2.98 2.07e-03 GO:0042330 taxis
1.97 2.26e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.55 2.45e-03 GO:0048519 negative regulation of biological process
2.05 2.78e-03 GO:0009890 negative regulation of biosynthetic process
1.65 2.83e-03 GO:0048513 organ development
1.97 2.98e-03 GO:0009888 tissue development
19.01 3.32e-03 GO:0006208 pyrimidine base catabolic process
2.12 3.39e-03 GO:0010629 negative regulation of gene expression
1.45 3.95e-03 GO:0009058 biosynthetic process
1.72 4.35e-03 GO:0006996 organelle organization
2.07 5.96e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.75 6.47e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.27 6.98e-03 GO:0044238 primary metabolic process
1.87 7.22e-03 GO:0031324 negative regulation of cellular metabolic process
16.89 7.27e-03 GO:0046113 nucleobase catabolic process
4.60 7.57e-03 GO:0050770 regulation of axonogenesis
2.49 7.78e-03 GO:0006325 chromatin organization
1.70 8.57e-03 GO:0009893 positive regulation of metabolic process
2.06 9.21e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.12 9.52e-03 GO:0007155 cell adhesion
2.37 1.05e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.10 1.17e-02 GO:0022610 biological adhesion
4.68 1.46e-02 GO:0001764 neuron migration
1.14 1.71e-02 GO:0009987 cellular process
4.56 1.91e-02 GO:0030902 hindbrain development
1.69 2.29e-02 GO:0031325 positive regulation of cellular metabolic process
2.16 2.31e-02 GO:0051094 positive regulation of developmental process
2.32 2.37e-02 GO:0040008 regulation of growth
1.80 3.34e-02 GO:0010605 negative regulation of macromolecule metabolic process
3.36 3.98e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
3.36 3.98e-02 GO:0022604 regulation of cell morphogenesis
3.95 4.06e-02 GO:0021953 central nervous system neuron differentiation
2.16 4.20e-02 GO:0051276 chromosome organization
12.67 4.21e-02 GO:0006206 pyrimidine base metabolic process
1.75 4.23e-02 GO:0009892 negative regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.71 6.95e-20 GO:0005634 nucleus
1.32 1.89e-16 GO:0005622 intracellular
1.32 3.95e-15 GO:0044424 intracellular part
1.34 2.40e-12 GO:0043229 intracellular organelle
1.34 4.00e-12 GO:0043226 organelle
1.30 6.70e-08 GO:0043231 intracellular membrane-bounded organelle
1.30 8.80e-08 GO:0043227 membrane-bounded organelle
1.97 1.24e-07 GO:0005856 cytoskeleton
1.85 1.67e-07 GO:0044428 nuclear part
1.13 8.89e-07 GO:0005623 cell
1.13 8.89e-07 GO:0044464 cell part
1.65 2.10e-06 GO:0043228 non-membrane-bounded organelle
1.65 2.10e-06 GO:0043232 intracellular non-membrane-bounded organelle
2.47 7.15e-06 GO:0043005 neuron projection
2.00 9.17e-06 GO:0042995 cell projection
1.80 3.60e-05 GO:0031981 nuclear lumen
2.37 4.74e-05 GO:0015630 microtubule cytoskeleton
5.26 9.65e-05 GO:0030426 growth cone
5.07 1.53e-04 GO:0030427 site of polarized growth
1.51 1.73e-04 GO:0043234 protein complex
2.15 2.69e-04 GO:0044451 nucleoplasm part
1.95 3.40e-04 GO:0044430 cytoskeletal part
2.88 6.19e-04 GO:0005874 microtubule
2.52 2.10e-03 GO:0044297 cell body
2.55 2.44e-03 GO:0043025 neuronal cell body
1.35 2.68e-03 GO:0044422 organelle part
1.60 2.93e-03 GO:0070013 intracellular organelle lumen
1.60 3.14e-03 GO:0043233 organelle lumen
1.59 3.82e-03 GO:0031974 membrane-enclosed lumen
13.82 4.02e-03 GO:0071565 nBAF complex
1.34 4.40e-03 GO:0044446 intracellular organelle part
1.76 7.58e-03 GO:0005654 nucleoplasm
2.00 7.81e-03 GO:0030054 cell junction
2.57 1.41e-02 GO:0030424 axon
2.49 1.61e-02 GO:0015629 actin cytoskeleton
1.19 1.71e-02 GO:0005737 cytoplasm
1.36 1.92e-02 GO:0032991 macromolecular complex
3.76 2.16e-02 GO:0000790 nuclear chromatin
3.94 2.82e-02 GO:0030027 lamellipodium
2.04 3.20e-02 GO:0045202 synapse
13.52 3.47e-02 GO:0071564 npBAF complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.35 2.60e-19 GO:0005488 binding
1.56 1.04e-14 GO:0005515 protein binding
1.77 8.67e-10 GO:0003676 nucleic acid binding
2.05 3.09e-08 GO:0008270 zinc ion binding
1.85 2.50e-07 GO:0003677 DNA binding
1.81 5.43e-06 GO:0046914 transition metal ion binding
2.11 1.11e-05 GO:0030528 transcription regulator activity
3.60 2.37e-05 GO:0003682 chromatin binding
2.16 6.15e-05 GO:0001071 nucleic acid binding transcription factor activity
2.16 6.15e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.43 6.40e-04 GO:0046872 metal ion binding
1.41 1.26e-03 GO:0043169 cation binding
1.41 1.55e-03 GO:0043167 ion binding
16.89 1.62e-03 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
5.96 1.97e-03 GO:0008013 beta-catenin binding
1.89 4.24e-03 GO:0019899 enzyme binding
2.10 1.22e-02 GO:0008092 cytoskeletal protein binding
1.49 1.30e-02 GO:0000166 nucleotide binding
15.20 2.77e-02 GO:0045294 alpha-catenin binding