Motif ID: SPZ1.p2

Z-value: 1.848

Transcription factors associated with SPZ1.p2:

NameEntrezDescription
Spz1 79401 spermatogenic leucine zipper 1



Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr11_-_98190774 15.470 NM_010895
Neurod2
neurogenic differentiation 2
chr8_-_108467294 10.363 NM_008490
Lcat
lecithin cholesterol acyltransferase
chr4_+_128560786 8.899 Trim62
tripartite motif-containing 62
chr7_+_53651811 8.684 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr15_+_91881593 8.531 NM_001159648
Cntn1
contactin 1
chr4_-_133054355 8.299 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr14_+_66587319 8.254 NM_013492
Clu
clusterin
chr5_-_21850490 8.199 NM_011261
Reln
reelin
chr10_+_128346900 7.357 NM_007653
Cd63
CD63 antigen
chr12_-_77811119 6.911 Spnb1
spectrin beta 1
chr10_+_122115755 6.908 NM_001110218
NM_176919
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr12_-_73509668 6.728 Rtn1
reticulon 1
chr5_+_137506122 6.537 NM_001039385
Vgf
VGF nerve growth factor inducible
chr2_+_129419252 6.384 Sirpa
signal-regulatory protein alpha
chr15_-_58913543 6.244 NM_001146180
NM_144800
Mtss1

metastasis suppressor 1

chr14_-_55400722 6.146 NM_016972
Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr15_+_82086506 5.863 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr6_-_113841295 5.722 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr13_+_109906361 5.632 Pde4d
phosphodiesterase 4D, cAMP specific
chr4_+_129190824 5.631 NM_010807
Marcksl1
MARCKS-like 1
chr6_-_119280616 5.615 NM_172492
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr14_+_34736806 5.560 Gdf10
growth differentiation factor 10
chr16_-_20621287 5.430 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_-_124414668 5.325 NM_153508
Clstn3
calsyntenin 3
chr4_+_129662110 5.288 Bai2
brain-specific angiogenesis inhibitor 2
chr5_-_69732792 5.280 Kctd8
potassium channel tetramerisation domain containing 8
chr1_+_75502181 5.253 Obsl1
obscurin-like 1
chr14_-_102007883 5.244 Tbc1d4
TBC1 domain family, member 4
chr10_-_108447894 5.232 Syt1
synaptotagmin I
chr6_-_60778740 5.216 NM_001042451
Snca
synuclein, alpha
chr1_-_84692352 5.213 Dner
delta/notch-like EGF-related receptor
chr17_+_34766489 5.175 NM_030890
Prrt1
proline-rich transmembrane protein 1
chr4_-_25726753 5.044 Fut9
fucosyltransferase 9
chr1_-_137584672 5.003 Nav1
neuron navigator 1
chr9_+_27598853 4.922 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr2_-_93797176 4.878 NM_001145034
Gm13889
predicted gene 13889
chr4_+_129662284 4.850 NM_173071
Bai2
brain-specific angiogenesis inhibitor 2
chr6_+_66846377 4.800 NM_001177556
NM_001177557
NM_001177559
NM_001177560
NM_025278
Gng12




guanine nucleotide binding protein (G protein), gamma 12




chr2_+_28048592 4.760 NM_001038613
NM_001038614
Olfm1

olfactomedin 1

chr17_+_27792487 4.748 Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr14_+_70857227 4.747 NM_145981
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr6_+_114081227 4.713 NM_172890
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr7_-_134968017 4.686 NM_024414
Stx1b
syntaxin 1B
chr10_+_122116066 4.607 Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr18_+_36440748 4.597 NM_008989
Pura
purine rich element binding protein A
chr2_-_180891448 4.537 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr7_-_134164627 4.471 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr12_+_91050912 4.469 Nrxn3
neurexin III
chr9_+_107242932 4.445 NM_175486
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr17_-_45686604 4.423 NM_001013749
Tmem151b
transmembrane protein 151B
chr7_-_26460133 4.373 Tmem91
transmembrane protein 91
chr18_-_32109233 4.305 NM_001025381
Gpr17
G protein-coupled receptor 17
chr15_+_51871652 4.298 NM_175503
Aard
alanine and arginine rich domain containing protein
chr4_-_66065499 4.281 NM_019514
NM_207109
Astn2

astrotactin 2

chr1_+_171585621 4.255 NM_009063
Rgs5
regulator of G-protein signaling 5
chr6_-_113841356 4.203 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr7_-_88851798 4.196 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr13_+_19040215 4.172 NM_175007
Amph
amphiphysin
chr5_-_135223110 4.170 NM_007925
Eln
elastin
chr16_-_85173978 4.097 App
amyloid beta (A4) precursor protein
chr9_+_51573434 4.072 NM_175535
Arhgap20
Rho GTPase activating protein 20
chr15_-_8660462 3.965 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_93076578 3.920 Ramp1
receptor (calcitonin) activity modifying protein 1
chr2_-_153355706 3.900 NM_001134300
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr10_-_49508472 3.898 NM_001111268
NM_010349
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr1_+_155500166 3.864 NM_026380
Rgs8
regulator of G-protein signaling 8
chr7_-_27966073 3.855 Mia1
melanoma inhibitory activity 1
chr12_-_101963277 3.818 Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr10_-_108448003 3.808 Syt1
synaptotagmin I
chr18_+_38578583 3.755 NM_022996
Ndfip1
Nedd4 family interacting protein 1
chr11_-_69419419 3.746 NM_013415
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_-_55531726 3.677 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr18_+_36441115 3.668 Pura
purine rich element binding protein A
chr9_-_86775282 3.658 Snap91
synaptosomal-associated protein 91
chr8_+_65430028 3.654 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr17_-_90855291 3.616


chr19_+_4510471 3.605 NM_001162946
Pcx
pyruvate carboxylase
chr14_+_34736772 3.582 NM_145741
Gdf10
growth differentiation factor 10
chr4_+_15808409 3.568 NM_009788
Calb1
calbindin 1
chrX_-_161765324 3.545 Glra2
glycine receptor, alpha 2 subunit
chr4_-_25727109 3.533 NM_010243
Fut9
fucosyltransferase 9
chr2_+_155601077 3.487 NM_010808
Mmp24
matrix metallopeptidase 24
chr2_-_127346987 3.473 Kcnip3
Kv channel interacting protein 3, calsenilin
chr11_+_75345598 3.470 Slc43a2
solute carrier family 43, member 2
chr15_-_83936038 3.444 Sult4a1
sulfotransferase family 4A, member 1
chr17_+_70318707 3.409 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_25733302 3.375 NM_175462
Kcnt1
potassium channel, subfamily T, member 1
chr8_-_125201971 3.357 NM_001109873
NM_177289
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr4_-_68615382 3.347 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr9_-_56483379 3.299 Lingo1
leucine rich repeat and Ig domain containing 1
chr5_-_123582394 3.264 Rhof
ras homolog gene family, member f
chr10_-_59079420 3.239 Ccdc109a
coiled-coil domain containing 109A
chr9_-_115219177 3.238 Stt3b
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr15_-_8660442 3.214 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_84692750 3.214 NM_152915
Dner
delta/notch-like EGF-related receptor
chr6_-_126114938 3.184 NM_001164035
Ntf3
neurotrophin 3
chr11_+_68901989 3.160 Vamp2
vesicle-associated membrane protein 2
chr1_-_133421746 3.125 Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_107776248 3.117 Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chrX_-_19868889 3.109 NM_177353
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr11_+_3414884 3.092 Selm
selenoprotein M
chr10_+_59569206 3.066 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr13_-_52626065 3.040 NM_001024474
Diras2
DIRAS family, GTP-binding RAS-like 2
chrX_+_20265522 3.035 Cdk16
cyclin-dependent kinase 16
chr16_-_85173944 3.034 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr4_+_104040160 3.027 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr7_-_116925058 3.020 NM_020610
Nrip3
nuclear receptor interacting protein 3
chr14_+_45970767 3.010 NM_019637
Styx
serine/threonine/tyrosine interaction protein
chr4_-_53172748 2.976 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr9_-_83699706 2.917 NM_001145974
NM_148941
Elovl4

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4

chr19_-_59150001 2.903 4930506M07Rik
RIKEN cDNA 4930506M07 gene
chr2_-_181194085 2.903 NM_028125
Zbtb46
zinc finger and BTB domain containing 46
chrX_+_147778717 2.882 NM_198105
Fam120c
family with sequence similarity 120, member C
chr16_+_31428887 2.878 Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chrX_-_157432580 2.839 NM_001024624
Cdkl5
cyclin-dependent kinase-like 5
chr11_-_33743416 2.798 NM_001190885
NM_027398
Kcnip1

Kv channel-interacting protein 1

chr1_+_50984361 2.795 NM_019790
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr2_+_144993587 2.793 Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_+_134094045 2.711 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr4_-_119212968 2.689 AA415398
expressed sequence AA415398
chr1_-_160286359 2.679 NM_207583
Fam5b
family with sequence similarity 5, member B
chr16_-_52453104 2.660 NM_009655
Alcam
activated leukocyte cell adhesion molecule
chr13_-_16115192 2.641 B230303A05Rik
RIKEN cDNA B230303A05 gene
chr10_-_53795485 2.635 Man1a
mannosidase 1, alpha
chr6_+_77192615 2.630 NM_028880
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr19_+_45122281 2.621 Sfxn3
sideroflexin 3
chr1_-_167390568 2.611 NM_028759
Dcaf6
DDB1 and CUL4 associated factor 6
chr17_+_37182986 2.604 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_17576750 2.592 NM_144852
Slc7a4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
chr6_-_125444722 2.592 NM_007657
Cd9
CD9 antigen
chr5_-_136410488 2.589 NM_018871
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr17_-_66868909 2.582 NM_024448
Rab12
RAB12, member RAS oncogene family
chr6_-_146450669 2.574 Itpr2
inositol 1,4,5-triphosphate receptor 2
chrX_-_101396356 2.568 NM_001077354
C77370
expressed sequence C77370
chr17_+_25707771 2.559 2810468N07Rik
RIKEN cDNA 2810468N07 gene
chr6_+_125095236 2.549 NM_178787
NM_001039669
Iffo1

intermediate filament family orphan 1

chr2_+_149656518 2.549 NM_001085521
Tmem90b
transmembrane protein 90B
chrX_+_162676910 2.542 Gpm6b
glycoprotein m6b
chr10_-_24919916 2.524 Akap7
A kinase (PRKA) anchor protein 7
chr8_-_87461251 2.523 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr2_+_37372112 2.497 NM_177383
Gpr21
G protein-coupled receptor 21
chr7_+_35971403 2.459 NM_017394
Slc7a10
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr1_+_174430359 2.426 NM_178598
Tagln2
transgelin 2
chr11_-_116515361 2.423 Cygb
cytoglobin
chr14_-_32249250 2.412 Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr9_-_86775154 2.393 NM_013669
Snap91
synaptosomal-associated protein 91
chr11_-_95936914 2.380 NM_001161419
NM_007506
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr18_+_38115192 2.367 NM_153793
Rell2
RELT-like 2
chr10_-_127057998 2.366 Lrp1
low density lipoprotein receptor-related protein 1
chr10_+_69169221 2.360 Ank3
ankyrin 3, epithelial
chr11_+_102622885 2.352 Adam11
a disintegrin and metallopeptidase domain 11
chr12_+_70342818 2.331 NM_178253
Klhdc1
kelch domain containing 1
chr18_+_37975071 2.321 Pcdhgc4
protocadherin gamma subfamily C, 4
chr17_+_43705388 2.295 NM_013737
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr4_-_68615283 2.293 Dbc1
deleted in bladder cancer 1 (human)
chr19_+_6497834 2.266


chr5_-_128938813 2.252 NM_172885
Tmem132d
transmembrane protein 132D
chr17_+_43705510 2.251 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr10_-_61802889 2.234 NM_001146100
Hk1
hexokinase 1
chr12_-_73509537 2.228 Rtn1
reticulon 1
chr1_+_60466462 2.212 NM_001198570
NM_001198571
NM_198127
Abi2


abl-interactor 2


chr18_-_31476721 2.197 NM_009065
Rit2
Ras-like without CAAX 2
chr7_+_56501558 2.184 NM_175272
Nav2
neuron navigator 2
chr3_-_115417685 2.160 S1pr1
sphingosine-1-phosphate receptor 1
chr15_-_8660479 2.122 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_116442760 2.116 NM_173755
Ube2o
ubiquitin-conjugating enzyme E2O
chr11_-_118216819 2.115 Timp2
tissue inhibitor of metalloproteinase 2
chr19_-_18706239 2.104 NM_017375
Ostf1
osteoclast stimulating factor 1
chr10_+_128370814 2.099 NM_008398
Itga7
integrin alpha 7
chr16_-_67621054 2.076 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr18_+_35020859 2.072 NM_007913
Egr1
early growth response 1
chr17_-_27650285 2.068 Grm4
glutamate receptor, metabotropic 4
chr9_+_56712850 2.056 NM_139001
Cspg4
chondroitin sulfate proteoglycan 4
chr12_-_80108263 2.048 NM_178745
Tmem229b
transmembrane protein 229B
chr5_+_150214363 2.046 NM_027519
6330406I15Rik
RIKEN cDNA 6330406I15 gene
chr4_+_137220675 2.041 Rap1gap
Rap1 GTPase-activating protein
chr12_-_5382487 2.038 NM_001164493
Klhl29
kelch-like 29 (Drosophila)
chr11_+_94072732 2.037 NM_009427
Tob1
transducer of ErbB-2.1
chr11_-_94902584 2.030 NM_133667
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr19_+_23215704 2.011 NM_010638
Klf9
Kruppel-like factor 9
chr3_-_101408495 2.007 NM_144900
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr9_-_31019234 2.007 Aplp2
amyloid beta (A4) precursor-like protein 2
chr2_+_129418930 1.999 NM_001177647
NM_007547
Sirpa

signal-regulatory protein alpha

chr4_+_53453302 1.995 Slc44a1
solute carrier family 44, member 1
chr18_+_64425037 1.987 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr1_-_157264398 1.983 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr9_+_45178267 1.980 NM_022004
Fxyd6
FXYD domain-containing ion transport regulator 6
chr7_+_138079669 1.978 NM_019564
Htra1
HtrA serine peptidase 1
chr7_+_26091105 1.976 NM_183311
Tmem145
transmembrane protein 145
chr2_-_180891704 1.975 NM_007906
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr11_-_118216625 1.975 Timp2
tissue inhibitor of metalloproteinase 2
chr16_+_96689322 1.972


chr10_-_30522912 1.924 NM_172495
Ncoa7
nuclear receptor coactivator 7
chr2_-_91803660 1.923 NM_138306
Dgkz
diacylglycerol kinase zeta
chr12_+_75385267 1.922 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr2_+_121121189 1.919 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr8_+_36650839 1.914 NM_001081279
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr9_-_29219382 1.908 Ntm
neurotrimin
chr16_+_41533317 1.908 NM_175548
Lsamp
limbic system-associated membrane protein
chr2_+_70956105 1.906 NM_028593
Cybrd1
cytochrome b reductase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.48 6.03e-08 GO:0007399 nervous system development
1.78 8.82e-08 GO:0051179 localization
1.88 1.23e-07 GO:0006810 transport
1.86 1.47e-07 GO:0051234 establishment of localization
3.46 2.80e-06 GO:0048666 neuron development
4.19 4.65e-06 GO:0007268 synaptic transmission
3.67 1.67e-05 GO:0031175 neuron projection development
3.59 2.60e-05 GO:0019226 transmission of nerve impulse
3.59 2.60e-05 GO:0035637 multicellular organismal signaling
2.48 8.28e-05 GO:0006811 ion transport
2.44 1.32e-04 GO:0022008 neurogenesis
2.48 1.76e-04 GO:0048699 generation of neurons
3.43 3.92e-04 GO:0000904 cell morphogenesis involved in differentiation
3.79 4.94e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.71 5.00e-04 GO:0048731 system development
9.21 5.39e-04 GO:0007269 neurotransmitter secretion
2.75 5.44e-04 GO:0030182 neuron differentiation
2.64 5.46e-04 GO:0006812 cation transport
2.31 7.87e-04 GO:0048468 cell development
3.81 8.95e-04 GO:0031644 regulation of neurological system process
2.79 9.10e-04 GO:0030030 cell projection organization
3.00 9.27e-04 GO:0044057 regulation of system process
3.62 1.01e-03 GO:0048812 neuron projection morphogenesis
3.92 1.15e-03 GO:0051969 regulation of transmission of nerve impulse
2.72 1.58e-03 GO:0030001 metal ion transport
3.99 1.79e-03 GO:0050804 regulation of synaptic transmission
3.74 2.27e-03 GO:0007409 axonogenesis
2.82 4.40e-03 GO:0007267 cell-cell signaling
2.67 5.17e-03 GO:0032989 cellular component morphogenesis
5.45 6.85e-03 GO:0006836 neurotransmitter transport
1.59 7.16e-03 GO:0048856 anatomical structure development
4.23 7.64e-03 GO:0006813 potassium ion transport
5.93 8.49e-03 GO:0001505 regulation of neurotransmitter levels
2.69 1.03e-02 GO:0000902 cell morphogenesis
2.82 1.08e-02 GO:0007610 behavior
2.99 1.79e-02 GO:0048858 cell projection morphogenesis
2.98 1.88e-02 GO:0015672 monovalent inorganic cation transport
3.85 2.30e-02 GO:0060627 regulation of vesicle-mediated transport
2.94 2.39e-02 GO:0032990 cell part morphogenesis
1.80 2.45e-02 GO:0023051 regulation of signaling
2.21 2.52e-02 GO:0055085 transmembrane transport
4.26 3.32e-02 GO:0043087 regulation of GTPase activity
4.22 3.59e-02 GO:0033124 regulation of GTP catabolic process
1.50 3.66e-02 GO:0007275 multicellular organismal development
6.44 3.88e-02 GO:0050808 synapse organization
1.16 4.39e-02 GO:0009987 cellular process
1.47 4.64e-02 GO:0032502 developmental process
2.99 4.81e-02 GO:0006140 regulation of nucleotide metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.22 3.14e-16 GO:0043005 neuron projection
1.87 4.80e-13 GO:0071944 cell periphery
4.06 1.45e-12 GO:0045202 synapse
1.86 2.58e-12 GO:0005886 plasma membrane
2.74 4.60e-11 GO:0042995 cell projection
4.33 9.06e-10 GO:0044456 synapse part
1.41 2.07e-09 GO:0016020 membrane
1.18 2.73e-09 GO:0005623 cell
1.18 2.73e-09 GO:0044464 cell part
1.37 1.22e-07 GO:0005737 cytoplasm
3.92 2.10e-07 GO:0043025 neuronal cell body
3.73 6.25e-07 GO:0044297 cell body
4.16 1.07e-06 GO:0030424 axon
1.93 6.86e-06 GO:0044459 plasma membrane part
2.87 2.49e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
2.81 2.70e-05 GO:0031988 membrane-bounded vesicle
4.94 4.03e-05 GO:0030136 clathrin-coated vesicle
4.61 4.47e-05 GO:0030135 coated vesicle
2.45 4.77e-05 GO:0031982 vesicle
1.36 5.08e-05 GO:0044425 membrane part
2.47 7.58e-05 GO:0031410 cytoplasmic vesicle
3.48 1.11e-04 GO:0030425 dendrite
1.22 1.72e-04 GO:0044424 intracellular part
1.22 2.33e-04 GO:0005622 intracellular
9.01 5.64e-04 GO:0042734 presynaptic membrane
4.31 5.70e-04 GO:0030659 cytoplasmic vesicle membrane
4.20 7.80e-04 GO:0045211 postsynaptic membrane
4.17 8.43e-04 GO:0044433 cytoplasmic vesicle part
3.91 1.89e-03 GO:0012506 vesicle membrane
2.07 2.22e-03 GO:0005626 insoluble fraction
1.90 2.92e-03 GO:0031090 organelle membrane
5.01 3.06e-03 GO:0008021 synaptic vesicle
1.90 3.75e-03 GO:0000267 cell fraction
22.52 3.88e-03 GO:0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle
22.52 3.88e-03 GO:0061202 clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
1.34 4.04e-03 GO:0044444 cytoplasmic part
2.06 4.07e-03 GO:0005624 membrane fraction
6.67 5.82e-03 GO:0030665 clathrin coated vesicle membrane
20.02 6.86e-03 GO:0060198 clathrin sculpted vesicle
4.10 9.59e-03 GO:0033267 axon part
1.31 9.91e-03 GO:0031224 intrinsic to membrane
2.53 1.22e-02 GO:0044463 cell projection part
3.36 2.04e-02 GO:0045121 membrane raft
1.30 2.10e-02 GO:0016021 integral to membrane
2.42 2.41e-02 GO:0005768 endosome
5.15 3.88e-02 GO:0030662 coated vesicle membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
1.45 3.57e-06 GO:0005515 protein binding
1.26 3.70e-06 GO:0005488 binding
2.59 4.26e-06 GO:0022891 substrate-specific transmembrane transporter activity
2.40 2.80e-05 GO:0022857 transmembrane transporter activity
2.36 2.89e-05 GO:0022892 substrate-specific transporter activity
2.57 5.95e-05 GO:0015075 ion transmembrane transporter activity
2.17 1.01e-04 GO:0005215 transporter activity
2.72 1.80e-04 GO:0019904 protein domain specific binding
2.84 1.08e-03 GO:0008289 lipid binding
2.63 1.22e-03 GO:0008324 cation transmembrane transporter activity
3.71 4.75e-03 GO:0005543 phospholipid binding
22.52 5.29e-03 GO:0008191 metalloendopeptidase inhibitor activity
22.52 5.29e-03 GO:0048551 metalloenzyme inhibitor activity
13.25 8.85e-03 GO:0015079 potassium ion transmembrane transporter activity
5.41 1.40e-02 GO:0005275 amine transmembrane transporter activity
1.66 1.50e-02 GO:0032555 purine ribonucleotide binding
1.66 1.52e-02 GO:0032553 ribonucleotide binding
18.02 1.53e-02 GO:0010576 metalloenzyme regulator activity
1.65 1.69e-02 GO:0017076 purine nucleotide binding
4.31 1.72e-02 GO:0017124 SH3 domain binding
2.80 1.98e-02 GO:0022804 active transmembrane transporter activity
2.00 2.28e-02 GO:0030234 enzyme regulator activity
5.72 2.48e-02 GO:0015171 amino acid transmembrane transporter activity
1.64 2.83e-02 GO:0035639 purine ribonucleoside triphosphate binding
7.95 3.10e-02 GO:0015179 L-amino acid transmembrane transporter activity
2.55 4.64e-02 GO:0032403 protein complex binding