Motif ID: UCCAGUU

Z-value: 0.795

Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
mmu-miR-145 MIMAT0000157



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr11_-_11937330 10.167 NM_010345
Grb10
growth factor receptor bound protein 10
chr13_-_3917356 5.278 NM_019671
Net1
neuroepithelial cell transforming gene 1
chr5_+_143722032 4.596 NM_007984
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr3_+_5218545 4.381 NM_030708
Zfhx4
zinc finger homeodomain 4
chr6_+_30688050 4.305 NM_008590
Mest
mesoderm specific transcript
chr4_+_100449274 3.834 NM_198037
Cachd1
cache domain containing 1
chr6_+_83087016 3.801 NM_009106
NM_133641
Rtkn

rhotekin

chr6_-_31513817 3.548 NM_013723
Podxl
podocalyxin-like
chr12_-_28027541 3.543 NM_009234
Sox11
SRY-box containing gene 11
chr4_+_148178500 3.537 NM_001159344
NM_027195
Casz1

castor homolog 1, zinc finger (Drosophila)

chr7_-_26035683 3.455 NM_010155
Erf
Ets2 repressor factor
chr6_-_112897259 3.316 NM_080448
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr11_+_112643501 3.316 NM_011448
Sox9
SRY-box containing gene 9
chr4_+_124663673 3.171 NM_138683
Rspo1
R-spondin homolog (Xenopus laevis)
chr4_+_106584074 2.876 NM_023672
NM_198438
Ssbp3

single-stranded DNA binding protein 3

chr6_-_127100954 2.853 NM_009829
Ccnd2
cyclin D2
chr2_+_14976877 2.788 NM_029466
Arl5b
ADP-ribosylation factor-like 5B
chr2_-_150835067 2.744 NM_207204
Ninl
ninein-like
chr3_-_145312928 2.654 NM_010516
Cyr61
cysteine rich protein 61
chr2_-_153067043 2.635 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr10_+_12810593 2.481 NM_009538
Plagl1
pleiomorphic adenoma gene-like 1
chr14_-_98568744 2.467 NM_001038610
NM_007826
Dach1

dachshund 1 (Drosophila)

chr2_-_102026486 2.224 NM_178886
Ldlrad3
low density lipoprotein receptor class A domain containing 3
chr5_-_23536487 2.217 NM_053090
Fam126a
family with sequence similarity 126, member A
chr3_-_142544883 2.162 NM_178654
Pkn2
protein kinase N2
chr1_+_196446006 2.041 NM_008882
Plxna2
plexin A2
chr4_+_148892231 1.969 NM_023465
Ctnnbip1
catenin beta interacting protein 1
chr1_-_78193381 1.963 NM_001159520
NM_008781
Pax3

paired box gene 3

chr3_-_133207209 1.962 NM_001040400
Tet2
tet oncogene family member 2
chr1_+_12682510 1.950 NM_001198565
NM_001198566
Sulf1

sulfatase 1

chr9_-_96918641 1.913 NM_145134
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr4_-_109960078 1.880 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_-_63605745 1.879 NM_016769
Smad3
MAD homolog 3 (Drosophila)
chr13_-_108680257 1.852 NM_145456
Zswim6
zinc finger, SWIM domain containing 6
chr5_-_86601756 1.806 NM_172712
Uba6
ubiquitin-like modifier activating enzyme 6
chr16_+_17452048 1.789 NM_007764
Crkl
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr15_+_57526212 1.783 NM_199449
Zhx2
zinc fingers and homeoboxes 2
chr11_-_97049185 1.759 NM_008379
Kpnb1
karyopherin (importin) beta 1
chr16_+_4639921 1.758 NM_139307
Vasn
vasorin
chr9_-_45792865 1.755 NM_008775
Pafah1b2
2610005M20Rik
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
RIKEN cDNA 2610005M20 gene
chr14_+_59820064 1.738 NM_027764
Rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr13_+_56804370 1.737 NM_008541
NM_001164041
Smad5

MAD homolog 5 (Drosophila)

chr2_-_84490827 1.672 NM_001085448
NM_001085449
NM_001085450
NM_007615
Ctnnd1



catenin (cadherin associated protein), delta 1



chr19_-_28085534 1.660 NM_011265
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr9_+_65478364 1.656 NM_028030
Rbpms2
RNA binding protein with multiple splicing 2
chr10_-_13043959 1.652 NM_001033257
NM_001195096
Phactr2

phosphatase and actin regulator 2

chr15_-_90880241 1.640 NM_001109040
NM_001109041
NM_001109042
NM_016705
Kif21a



kinesin family member 21A



chr18_+_83080270 1.626 NM_183033
Zfp516
zinc finger protein 516
chr2_-_65405546 1.613 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_+_102862151 1.581 NM_010937
Nras
neuroblastoma ras oncogene
chr12_+_21117592 1.580 NM_001004364
NM_001098168
NM_001135192
Asap2


ArfGAP with SH3 domain, ankyrin repeat and PH domain 2


chr4_-_131767968 1.548 NM_145393
Ythdf2
YTH domain family 2
chr2_+_92024338 1.507 NM_138755
Phf21a
PHD finger protein 21A
chr2_-_72817311 1.500 NM_001098425
Sp3
trans-acting transcription factor 3
chr9_+_59139356 1.495 NM_028121
Adpgk
ADP-dependent glucokinase
chr8_+_74659107 1.476 NM_001001491
Tpm4
tropomyosin 4
chr11_+_77499638 1.475 NM_001024205
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chrX_-_138825032 1.442 NM_001033600
NM_019477
NM_207625
Acsl4


acyl-CoA synthetase long-chain family member 4


chr2_-_103637096 1.414 NM_001111289
NM_001111290
NM_001111292
Caprin1


cell cycle associated protein 1


chr16_+_13256573 1.389 NM_001122667
Mkl2
MKL/myocardin-like 2
chr8_-_90483392 1.385 NM_033327
Zfp423
zinc finger protein 423
chr10_-_9394979 1.364 NM_177271
Samd5
sterile alpha motif domain containing 5
chr14_+_66456138 1.362 NM_145944
Ccdc25
coiled-coil domain containing 25
chr6_-_39156706 1.290 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr1_-_168339909 1.286 NM_001142948
NM_175170
Pogk

pogo transposable element with KRAB domain

chr4_+_21858472 1.183 NM_175234
6230409E13Rik
RIKEN cDNA 6230409E13 gene
chr1_-_121545442 1.178 NM_001113416
NM_145506
Epb4.1l5

erythrocyte protein band 4.1-like 5

chr13_+_56805028 1.149 NM_001164042
Smad5
MAD homolog 5 (Drosophila)
chr2_-_74416925 1.137 NM_001110209
NM_027133
Lnp

limb and neural patterns

chr9_+_106356125 1.137 NM_021567
Pcbp4
poly(rC) binding protein 4
chr11_-_102559011 1.137 NM_025918
Ccdc43
coiled-coil domain containing 43
chr6_+_100783598 1.132 NM_182939
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chr7_+_75097142 1.128 NM_010513
Igf1r
insulin-like growth factor I receptor
chr9_+_102620096 1.116 NM_019764
Amotl2
angiomotin-like 2
chr9_+_50665024 1.104 NM_001034085
NM_028614
Ppp2r1b

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform

chr2_+_44966657 1.083 NM_001177394
Gm13476
predicted gene 13476
chr1_-_95375372 1.071 NM_133808
Hdlbp
high density lipoprotein (HDL) binding protein
chr2_+_92025639 1.064 NM_001109691
Phf21a
PHD finger protein 21A
chr1_+_162836541 1.062 NM_001024952
Rc3h1
RING CCCH (C3H) domains 1
chr19_-_7315495 1.062 NM_027643
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr17_+_78599556 1.026 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr11_+_62944973 1.018 NM_008885
Pmp22
peripheral myelin protein 22
chr14_-_71166340 1.014 NM_023045
Xpo7
exportin 7
chr1_+_153191613 0.994 NM_001039511
NM_001039512
NM_054102
Ivns1abp


influenza virus NS1A binding protein


chr5_-_115584921 0.970 NM_175352
Unc119b
unc-119 homolog B (C. elegans)
chr17_-_47970167 0.950 NM_010783
Mdfi
MyoD family inhibitor
chr1_+_63319842 0.944 NM_028673
Zdbf2
zinc finger, DBF-type containing 2
chr9_-_75407338 0.939 NM_016963
Tmod3
tropomodulin 3
chr3_-_84024766 0.905 NM_030706
Trim2
tripartite motif-containing 2
chr1_+_36125177 0.903 NM_015818
Hs6st1
heparan sulfate 6-O-sulfotransferase 1
chr11_-_77421308 0.900 NM_144825
Taok1
TAO kinase 1
chr16_+_17233664 0.899 NM_178922
Hic2
hypermethylated in cancer 2
chr4_+_132194931 0.867 NM_210071
NM_211357
NM_010166
Eya3


5830409B07Rik
eyes absent 3 homolog (Drosophila)


RIKEN cDNA 5830409B07 gene
chr2_+_79547936 0.859 NM_172420
Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr16_+_22009551 0.852 NM_029457
Senp2
SUMO/sentrin specific peptidase 2
chr10_-_116813919 0.834 NM_001013391
Cpsf6
cleavage and polyadenylation specific factor 6
chr16_-_45844409 0.822 NM_153412
Phldb2
pleckstrin homology-like domain, family B, member 2
chr10_+_17443024 0.816 NM_010828
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr13_-_3892788 0.814 NM_001047159
Net1
neuroepithelial cell transforming gene 1
chr7_-_87065480 0.799 NM_009682
Ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr16_+_32608981 0.779 NM_011638
Tfrc
transferrin receptor
chr1_-_184271729 0.765 NM_175127
Fbxo28
F-box protein 28
chr11_-_88579517 0.749 NM_054043
Msi2
Musashi homolog 2 (Drosophila)
chr19_+_5041341 0.740 NM_134155
Brms1
breast cancer metastasis-suppressor 1
chr19_-_41876509 0.738 NM_001163495
NM_027667
Arhgap19

Rho GTPase activating protein 19

chr5_+_28397902 0.722 NM_153526
Insig1
insulin induced gene 1
chr14_-_73109722 0.717 NM_207636
Fndc3a
fibronectin type III domain containing 3A
chr17_-_71351775 0.716 NM_026064
2900073G15Rik
RIKEN cDNA 2900073G15 gene
chr11_-_96685326 0.698 NM_001130453
NM_001130454
NM_001130451
NM_001130452
Nfe2l1



nuclear factor, erythroid derived 2,-like 1



chr11_-_69373707 0.689 NM_007911
Efnb3
ephrin B3
chr13_+_112476313 0.684 NM_172593
Mier3
mesoderm induction early response 1, family member 3
chr2_-_104656852 0.682 NM_001123327
Qser1
glutamine and serine rich 1
chr1_-_58561631 0.677 NM_008765
Orc2
origin recognition complex, subunit 2
chr12_-_55963776 0.665 NM_007688
Cfl2
cofilin 2, muscle
chr11_+_116295406 0.662 NM_176902
Fam100b
family with sequence similarity 100, member B
chr4_+_32504409 0.658 NM_001109661
Bach2
BTB and CNC homology 2
chr7_-_128850659 0.655 NM_001033173
Usp31
ubiquitin specific peptidase 31
chr4_+_129497720 0.644 NM_008974
Ptp4a2
protein tyrosine phosphatase 4a2
chr4_-_142802606 0.640 NM_001081355
Prdm2
PR domain containing 2, with ZNF domain
chr15_-_79377170 0.640 NM_001040187
NM_199080
Ddx17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr5_+_139676589 0.633 NM_024451
Sun1
Sad1 and UNC84 domain containing 1
chr2_+_29917543 0.633 NM_023871
Set
SET nuclear oncogene
chr4_+_129497951 0.632 NM_001164745
Ptp4a2
5830469G19Rik
protein tyrosine phosphatase 4a2
RIKEN cDNA 5830469G19 gene
chr19_-_44144244 0.624 NM_001164359
NM_001164360
Erlin1

ER lipid raft associated 1

chrX_+_17739762 0.622 NM_009483
Kdm6a
4lysine (K)-specific demethylase 6A
chr10_+_127740390 0.615 NM_133992
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr4_-_108506131 0.614 NM_027453
Btf3l4
basic transcription factor 3-like 4
chr12_-_66174913 0.611 NM_013902
Fkbp3
FK506 binding protein 3
chr2_-_119303348 0.608 NM_026574
Ino80
INO80 homolog (S. cerevisiae)
chr9_+_44142772 0.607 NM_010436
H2afx
H2A histone family, member X
chr7_-_144506112 0.599 NM_001113414
NM_001113415
NM_010096
Ebf3


early B-cell factor 3


chr2_-_56967331 0.586 NM_013613
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr6_+_83085799 0.586 NM_001136227
Rtkn
rhotekin
chr13_-_112280018 0.566 NM_001122963
NM_028487
Gpbp1

GC-rich promoter binding protein 1

chr9_+_44412931 0.565 NM_001110826
NM_007841
NM_181324
Ddx6


DEAD (Asp-Glu-Ala-Asp) box polypeptide 6


chr9_-_35007458 0.565 NM_001177847
NM_001177846
NM_054096
Tirap


toll-interleukin 1 receptor (TIR) domain-containing adaptor protein


chr3_-_65762057 0.562 NM_019937
Ccnl1
cyclin L1
chrX_-_130432840 0.554 NM_019656
Tspan6
tetraspanin 6
chr5_-_52581705 0.549 NM_001042620
NM_007839
Dhx15

DEAH (Asp-Glu-Ala-His) box polypeptide 15

chr4_+_154865439 0.542 NM_001160016
NM_001160017
NM_008142
Gnb1


guanine nucleotide binding protein (G protein), beta 1


chr1_-_82287990 0.532 NM_010570
Irs1
insulin receptor substrate 1
chr2_+_73109981 0.529 NM_001005343
Sp9
trans-acting transcription factor 9
chr4_+_59202363 0.528 NM_011673
Ugcg
UDP-glucose ceramide glucosyltransferase
chr4_-_109959366 0.519 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr14_-_111154292 0.517 NM_175499
Slitrk6
SLIT and NTRK-like family, member 6
chr18_-_63851841 0.511 NM_016792
Txnl1
thioredoxin-like 1
chr13_-_41454358 0.510 NM_017464
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr11_+_115243203 0.505 NM_001080929
Cdr2l
cerebellar degeneration-related protein 2-like
chr4_-_55545337 0.504 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr17_+_83750246 0.503 NM_001114361
NM_001114362
NM_199466
Eml4


echinoderm microtubule associated protein like 4


chr8_+_112302530 0.497 NM_009677
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr11_+_77306825 0.493 NM_001004144
Git1
G protein-coupled receptor kinase-interactor 1
chr4_+_107107195 0.491 NM_147221
Glis1
GLIS family zinc finger 1
chr13_+_119503505 0.487 NM_008002
Fgf10
fibroblast growth factor 10
chr2_-_37278415 0.486 NM_001100591
Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr12_+_80130149 0.485 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr7_-_117758413 0.477 NM_177324
Sbf2
SET binding factor 2
chr1_+_133807034 0.475 NM_001145804
NM_175294
Nucks1

nuclear casein kinase and cyclin-dependent kinase substrate 1

chr11_+_93747419 0.471 NM_134012
Mbtd1
mbt domain containing 1
chr19_-_7557690 0.468 NM_053076
NM_001003933
NM_001003934
Rtn3


reticulon 3


chr11_+_115626733 0.460 NM_028014
2310067B10Rik
RIKEN cDNA 2310067B10 gene
chr7_-_29383180 0.460 NM_027470
Pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr9_-_62994774 0.446 NM_172446
NM_001163755
NM_001163757
Skor1


SKI family transcriptional corepressor 1


chr11_+_83116148 0.436 NM_001035854
NM_027915
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr15_+_101004502 0.427 NM_007395
Acvr1b
activin A receptor, type 1B
chr1_+_12708582 0.388 NM_172294
Sulf1
sulfatase 1
chr4_-_125879832 0.377 NM_146153
Thrap3
thyroid hormone receptor associated protein 3
chr19_+_29064938 0.376 NM_025950
Cdc37l1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr10_+_98725858 0.370 NM_026268
Dusp6
dual specificity phosphatase 6
chr6_-_149050201 0.363 NM_177192
Dennd5b
DENN/MADD domain containing 5B
chr2_+_173902521 0.357 NM_001102423
NM_001102424
NM_001102425
NM_172675
Stx16



syntaxin 16



chr5_-_143874629 0.354 NM_080561
NM_207110
Rnf216

ring finger protein 216

chr10_+_70810540 0.350 NM_027184
Ipmk
inositol polyphosphate multikinase
chr5_-_4104696 0.345 NM_020010
Cyp51
cytochrome P450, family 51
chr18_+_83084023 0.338 NM_001177464
Zfp516
zinc finger protein 516
chr3_+_19957807 0.313 NM_009210
NM_144959
Hltf

helicase-like transcription factor

chr5_+_102910409 0.309 NM_029270
NM_146161
Arhgap24

Rho GTPase activating protein 24

chr11_-_50729643 0.305 NM_001044697
NM_001044698
NM_001044699
NM_001044700
Zfp2



zinc finger protein 2



chr14_+_8650470 0.304 NM_134080
Flnb
filamin, beta
chr8_-_75016484 0.302 NM_177766
Slc35e1
solute carrier family 35, member E1
chr18_+_69505374 0.297 NM_001083967
Tcf4
transcription factor 4
chr7_+_148414663 0.292 NM_001081118
Phrf1
PHD and ring finger domains 1
chr14_-_32643594 0.287 NM_001024604
Ankrd28
ankyrin repeat domain 28
chr15_+_99803210 0.283 NM_001024526
Larp4
La ribonucleoprotein domain family, member 4
chr9_+_43552516 0.282 NM_021424
Pvrl1
poliovirus receptor-related 1
chr4_-_35104577 0.278 NM_178061
Mobkl2b
MOB1, Mps One Binder kinase activator-like 2B (yeast)
chr6_+_38383918 0.268 NM_177185
Ubn2
ubinuclein 2
chr17_+_79336458 0.267 NM_028611
2410091C18Rik
RIKEN cDNA 2410091C18 gene
chr13_+_94827750 0.265 NM_172589
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_+_13995715 0.262 NM_011484
Stam
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr16_-_98072833 0.254 NM_144789
Prdm15
PR domain containing 15
chr6_+_146673451 0.254 NM_172734
Stk38l
serine/threonine kinase 38 like
chrX_-_103124651 0.247 NM_009530
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr2_-_131855722 0.247 NM_175445
Rassf2
Ras association (RalGDS/AF-6) domain family member 2
chr13_+_47138896 0.246 NM_172262
Kdm1b
lysine (K)-specific demethylase 1B
chr11_+_82594636 0.235 NM_010716
Lig3
ligase III, DNA, ATP-dependent
chr12_+_85455277 0.234 NM_028821
Dnalc1
dynein, axonemal, light chain 1
chr3_+_95908422 0.233 NM_001025613
NM_001025614
Otud7b

OTU domain containing 7B

chr1_-_135557934 0.232 NM_144530
Zbed6
Zc3h11a
zinc finger, BED domain containing 6
zinc finger CCCH type containing 11A
chr17_-_68353397 0.231 NM_172964
Arhgap28
Rho GTPase activating protein 28

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.83 6.53e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.80 1.52e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.68 2.12e-04 GO:0031326 regulation of cellular biosynthetic process
2.65 2.75e-04 GO:0009889 regulation of biosynthetic process
2.37 5.69e-04 GO:0060255 regulation of macromolecule metabolic process
2.28 1.41e-03 GO:0031323 regulation of cellular metabolic process
2.71 1.56e-03 GO:0006355 regulation of transcription, DNA-dependent
2.55 1.67e-03 GO:0010468 regulation of gene expression
2.66 2.21e-03 GO:0051252 regulation of RNA metabolic process
2.14 2.22e-03 GO:0019222 regulation of metabolic process
3.00 2.98e-03 GO:0006351 transcription, DNA-dependent
2.99 3.06e-03 GO:0032774 RNA biosynthetic process
2.22 3.78e-03 GO:0080090 regulation of primary metabolic process
11.45 6.78e-03 GO:0030111 regulation of Wnt receptor signaling pathway
2.41 7.57e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.38 9.08e-03 GO:0051171 regulation of nitrogen compound metabolic process
2.30 1.07e-02 GO:0007275 multicellular organismal development
2.34 1.88e-02 GO:0048856 anatomical structure development
19.29 2.65e-02 GO:0001889 liver development
18.92 2.86e-02 GO:0061008 hepaticobiliary system development
2.40 3.14e-02 GO:0048731 system development
3.49 3.64e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.12 4.67e-02 GO:0032502 developmental process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment p-value GO term description
2.50 7.81e-04 GO:0003676 nucleic acid binding
33.53 9.22e-03 GO:0005520 insulin-like growth factor binding
2.62 1.12e-02 GO:0003677 DNA binding
3.71 1.64e-02 GO:0001071 nucleic acid binding transcription factor activity
3.71 1.64e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
5.23 3.70e-02 GO:0016563 transcription activator activity
1.37 4.10e-02 GO:0005488 binding