Motif ID: UUGGCAA

Z-value: 0.693

Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
mmu-miR-182 MIMAT0000211



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr15_-_56526052 5.226 NM_008216
Has2
hyaluronan synthase 2
chr2_+_37372112 4.339 NM_177383
Gpr21
G protein-coupled receptor 21
chr2_-_65405546 3.405 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr1_-_157264398 3.133 NM_011273
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_-_95867076 2.968 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr1_-_90598670 2.954 NM_177305
Arl4c
ADP-ribosylation factor-like 4C
chr7_+_69521858 2.611 NM_013779
Magel2
melanoma antigen, family L, 2
chr2_+_61642509 2.538 NM_009322
Tbr1
T-box brain gene 1
chr1_+_189821727 2.525 NM_011935
Esrrg
estrogen-related receptor gamma
chr14_-_80171003 2.489 NM_001042726
NM_021543
Pcdh8

protocadherin 8

chr16_-_65562921 2.384 NM_026879
Chmp2b
chromatin modifying protein 2B
chr2_+_65683823 2.309 NM_153409
NM_178634
Csrnp3

cysteine-serine-rich nuclear protein 3

chr6_+_15135505 2.306 NM_212435
Foxp2
forkhead box P2
chr9_+_47338431 2.254 NM_001025600
NM_018770
NM_207675
NM_207676
Cadm1



cell adhesion molecule 1



chr6_+_71657791 2.245 NM_178608
Reep1
receptor accessory protein 1
chr11_-_11937330 2.158 NM_010345
Grb10
growth factor receptor bound protein 10
chr6_+_17015148 2.022 NM_207176
Tes
testis derived transcript
chr1_+_19198994 2.018 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr4_+_104040160 1.910 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr6_+_14851348 1.876 NM_053242
Foxp2
forkhead box P2
chr10_+_86241749 1.847 NM_175331
Nt5dc3
5'-nucleotidase domain containing 3
chr4_-_91042997 1.837 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_+_160292470 1.813 NM_007495
Astn1
astrotactin 1
chr10_+_101621491 1.792 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chr5_+_31014229 1.789 NM_023047
Dpysl5
dihydropyrimidinase-like 5
chr17_-_36046961 1.706 NM_001142744
NM_001142745
NM_028476
Atat1


alpha tubulin acetyltransferase 1


chr4_-_109960078 1.694 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_102620096 1.674 NM_019764
Amotl2
angiomotin-like 2
chr14_+_12386043 1.669 NM_008981
Ptprg
protein tyrosine phosphatase, receptor type, G
chr1_-_107253245 1.654 NM_001160368
NM_178779
Rnf152

ring finger protein 152

chrX_+_139952975 1.608 NM_001195048
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_+_71574403 1.581 NM_008883
Plxna3
plexin A3
chr10_+_68996455 1.575 NM_146005
NM_170688
NM_170689
NM_170690
NM_170728
NM_170729
NM_170730
Ank3






ankyrin 3, epithelial






chr2_-_52414072 1.572 NM_146123
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chrX_-_71126088 1.562 NM_008478
L1cam
L1 cell adhesion molecule
chr18_-_75120759 1.557 NM_010720
Lipg
lipase, endothelial
chrX_+_55283804 1.532 NM_009575
Zic3
zinc finger protein of the cerebellum 3
chr8_-_30330079 1.464 NM_153135
Unc5d
unc-5 homolog D (C. elegans)
chr3_+_98186380 1.459 NM_172863
Zfp697
zinc finger protein 697
chr1_-_145851257 1.447 NM_009061
Rgs2
regulator of G-protein signaling 2
chr6_+_103460834 1.444 NM_007697
Chl1
cell adhesion molecule with homology to L1CAM
chrX_-_140367467 1.377 NM_001110222
NM_001110223
NM_001110224
NM_010025
Dcx



doublecortin



chr16_-_67621054 1.350 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr12_-_32398730 1.309 NM_175191
Gpr22
G protein-coupled receptor 22
chrX_+_132373572 1.295 NM_001163015
NM_001163016
NM_001163017
Gprasp2


G protein-coupled receptor associated sorting protein 2


chr6_-_93863547 1.292 NM_001083321
NM_001083320
Magi1

membrane associated guanylate kinase, WW and PDZ domain containing 1

chr15_-_84388245 1.272 NM_177630
Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr5_+_23606402 1.268 NM_001161800
NM_026448
Klhl7

kelch-like 7 (Drosophila)

chr11_+_29273673 1.264 NM_176841
Ccdc88a
coiled coil domain containing 88A
chr2_+_3035629 1.246 NM_001081161
Fam171a1
family with sequence similarity 171, member A1
chr5_+_30559138 1.229 NM_027652
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr1_+_57831651 1.228 NM_144882
Spats2l
spermatogenesis associated, serine-rich 2-like
chr6_-_31513817 1.183 NM_013723
Podxl
podocalyxin-like
chr7_+_3289029 1.180 NM_001093764
Myadm
myeloid-associated differentiation marker
chr3_+_108394195 1.172 NM_181400
Wdr47
WD repeat domain 47
chr15_-_37389073 1.166 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr12_+_72932064 1.165 NM_026102
NM_172464
Daam1

dishevelled associated activator of morphogenesis 1

chrX_-_61530170 1.094 NM_178740
Slitrk4
SLIT and NTRK-like family, member 4
chr1_+_61685397 1.062 NM_001081050
Pard3b
par-3 partitioning defective 3 homolog B (C. elegans)
chr16_-_17928270 1.045 NM_153150
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chrX_+_98835386 1.042 NM_139144
Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr8_+_114060341 1.033 NM_001168621
NM_001168622
NM_133206
Znrf1


zinc and ring finger 1


chr11_+_86940545 1.031 NM_197987
Trim37
tripartite motif-containing 37
chr1_-_158869650 1.029 NM_001159965
NM_001159967
NM_001159968
NM_023884
Ralgps2



Ral GEF with PH domain and SH3 binding motif 2



chr2_+_92439758 1.029 NM_023850
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr11_+_117193004 1.000 NM_017380
Sept9
septin 9
chr16_+_11984205 0.999 NM_001174086
NM_028277
Shisa9

shisa homolog 9 (Xenopus laevis)

chr5_+_130620730 0.992 NM_172509
Kctd7
potassium channel tetramerisation domain containing 7
chr15_-_27955602 0.990 NM_001081302
Trio
triple functional domain (PTPRF interacting)
chr1_+_7079000 0.984 NM_183028
Pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr10_+_126602182 0.963 NM_008080
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr3_+_33919000 0.956 NM_001113188
NM_001113189
NM_008053
Fxr1


fragile X mental retardation gene 1, autosomal homolog


chr2_+_157385835 0.951 NM_010923
NM_180960
Nnat

neuronatin

chr3_+_32716447 0.939 NM_001013024
Usp13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr9_-_62659364 0.933 NM_010193
Fem1b
feminization 1 homolog b (C. elegans)
chr14_-_103746016 0.923 NM_207215
Mycbp2
MYC binding protein 2
chr3_-_122322556 0.920 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr3_-_153388047 0.913 NM_011372
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr16_+_30065419 0.907 NM_008235
Hes1
hairy and enhancer of split 1 (Drosophila)
chr13_-_36826245 0.891 NM_153529
Nrn1
neuritin 1
chr19_-_17912073 0.884 NM_001163144
NM_001190483
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr4_+_8462766 0.883 NM_021518
Rab2a
RAB2A, member RAS oncogene family
chr2_-_121632749 0.877 NM_172673
Frmd5
FERM domain containing 5
chr15_-_63891810 0.865 NM_144846
Fam49b
family with sequence similarity 49, member B
chr19_+_5490454 0.845 NM_007687
Cfl1
cofilin 1, non-muscle
chr9_-_75459125 0.836 NM_016711
Tmod2
tropomodulin 2
chr5_-_114358647 0.827 NM_011779
Coro1c
coronin, actin binding protein 1C
chr16_-_63863905 0.822 NM_010140
Epha3
Eph receptor A3
chr13_-_117099629 0.816 NM_021459
Isl1
ISL1 transcription factor, LIM/homeodomain
chr4_-_133684599 0.811 NM_080559
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
chr3_+_45182311 0.810 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr11_-_101327431 0.801 NM_012037
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr10_-_116585527 0.791 NM_177798
Frs2
fibroblast growth factor receptor substrate 2
chr2_+_37298785 0.785 NM_146121
Rabgap1
RAB GTPase activating protein 1
chr11_+_32247758 0.784 NM_177364
Sh3pxd2b
SH3 and PX domains 2B
chr1_-_38954933 0.782 NM_145142
Chst10
carbohydrate sulfotransferase 10
chr1_-_138242666 0.762 NM_001081360
Camsap1l1
calmodulin regulated spectrin-associated protein 1-like 1
chr2_-_66473008 0.759 NM_018852
Scn9a
sodium channel, voltage-gated, type IX, alpha
chr16_+_78301923 0.755 NM_001025192
NM_009988
Cxadr

coxsackie virus and adenovirus receptor

chr14_+_21748646 0.744 NM_009502
Vcl
vinculin
chr3_-_31209216 0.743 NM_172861
Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr4_-_6917628 0.734 NM_145711
Tox
thymocyte selection-associated high mobility group box
chr19_-_50752974 0.733 NM_021377
Sorcs1
VPS10 domain receptor protein SORCS 1
chrX_+_156065141 0.729 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1
chr9_+_59426108 0.722 NM_175235
Celf6
CUGBP, Elav-like family member 6
chr1_-_99558490 0.721 NM_133825
D1Ertd622e
DNA segment, Chr 1, ERATO Doi 622, expressed
chr11_+_90110701 0.721 NM_026178
Mmd
monocyte to macrophage differentiation-associated
chr12_-_81213930 0.717 NM_007564
Zfp36l1
zinc finger protein 36, C3H type-like 1
chr14_-_65881225 0.713 NM_021458
Fzd3
frizzled homolog 3 (Drosophila)
chrX_-_71070284 0.712 NM_001029868
Pdzd4
PDZ domain containing 4
chr1_-_137327006 0.706 NM_153774
Ipo9
importin 9
chr16_-_17201556 0.701 NM_009456
Ube2l3
ubiquitin-conjugating enzyme E2L 3
chr8_-_49075884 0.700 NM_133791
Wwc2
WW, C2 and coiled-coil domain containing 2
chr11_-_74537877 0.692 NM_013625
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr18_-_46887869 0.691 NM_033037
Cdo1
cysteine dioxygenase 1, cytosolic
chr14_-_62058627 0.687 NM_008466
Kpna3
karyopherin (importin) alpha 3
chr16_-_91597886 0.682 NM_030018
Tmem50b
transmembrane protein 50B
chr11_+_87574041 0.681 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chrX_-_101866402 0.681 NM_175358
Zdhhc15
zinc finger, DHHC domain containing 15
chr5_-_123350242 0.678 NM_013910
Kdm2b
lysine (K)-specific demethylase 2B
chr11_-_12364886 0.669 NM_172496
Cobl
cordon-bleu
chr14_-_122138082 0.658 NM_001128307
NM_001128308
Dock9

dedicator of cytokinesis 9

chr4_+_43970559 0.653 NM_027450
Glipr2
GLI pathogenesis-related 2
chr7_-_56892061 0.624 NM_001005232
Dbx1
developing brain homeobox 1
chr11_+_60591019 0.624 NM_001085440
NM_175491
Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

chr7_+_53039273 0.623 NM_001005511
Lmtk3
lemur tyrosine kinase 3
chr8_-_92872139 0.621 NM_172913
Tox3
TOX high mobility group box family member 3
chr10_+_52137324 0.620 NM_030250
Nus1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr5_-_68238654 0.614 NM_001038999
NM_009727
Atp8a1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr14_-_27783615 0.595 NM_145221
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr11_+_121121273 0.595 NM_001080932
Foxk2
forkhead box K2
chr7_+_104728398 0.590 NM_001081267
Rsf1
remodeling and spacing factor 1
chr18_-_46685557 0.577 NM_173423
Fem1c
fem-1 homolog c (C.elegans)
chr6_+_54545104 0.570 NM_001164361
Plekha8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr8_-_89409079 0.569 NM_030563
N4bp1
NEDD4 binding protein 1
chr14_+_67852128 0.567 NM_010095
Ebf2
early B-cell factor 2
chr10_+_84849558 0.566 NM_028709
Btbd11
BTB (POZ) domain containing 11
chr9_+_106073255 0.563 NM_029896
Wdr82
WD repeat domain containing 82
chr8_+_13869640 0.557 NM_181854
Zfp828
zinc finger protein 828
chr10_+_95403283 0.554 NM_001001932
Eea1
early endosome antigen 1
chr5_-_8622882 0.550 NM_198620
Rundc3b
RUN domain containing 3B
chr8_+_124114323 0.541 NM_026160
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
chr8_-_97400173 0.540 NM_053246
Dok4
docking protein 4
chr2_-_6805937 0.534 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr2_+_4073908 0.525 NM_172475
Frmd4a
FERM domain containing 4A
chr7_+_104230260 0.524 NM_001162477
NM_010248
Gab2

growth factor receptor bound protein 2-associated protein 2

chr2_+_179777187 0.517 NM_178750
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr4_+_28740280 0.517 NM_001122889
NM_010141
Epha7

Eph receptor A7

chr12_+_113960379 0.517 NM_001024602
AW555464
expressed sequence AW555464
chrX_+_45265614 0.516 NM_177215
Ocrl
oculocerebrorenal syndrome of Lowe
chr13_-_41174986 0.513 NM_001145802
NM_001145803
Mak

male germ cell-associated kinase

chr6_+_4853319 0.512 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr19_+_45005608 0.508 NM_001081225
Fam178a
family with sequence similarity 178, member A
chr4_-_34634507 0.507 NM_011895
Slc35a1
solute carrier family 35 (CMP-sialic acid transporter), member 1
chr2_+_79547936 0.507 NM_172420
Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_+_45869473 0.505 NM_009616
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr10_+_17443024 0.488 NM_010828
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr14_+_32973077 0.485 NM_001033988
Ncoa4
nuclear receptor coactivator 4
chr1_+_163072784 0.477 NM_028664
Ankrd45
ankyrin repeat domain 45
chr1_+_74648028 0.476 NM_175031
Stk36
serine/threonine kinase 36 (fused homolog, Drosophila)
chr11_-_70468130 0.476 NM_011072
Pfn1
profilin 1
chr16_-_75766992 0.475 NM_030201
Hspa13
heat shock protein 70 family, member 13
chr9_-_95412264 0.472 NM_001114977
NM_026476
2610101N10Rik

RIKEN cDNA 2610101N10 gene

chr2_-_72818502 0.471 NM_001018042
Sp3
trans-acting transcription factor 3
chr12_+_45429857 0.470 NM_001146031
NM_176930
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr2_+_69627711 0.464 NM_028521
Phospho2
phosphatase, orphan 2
chr1_+_33776715 0.463 NM_008999
Rab23
RAB23, member RAS oncogene family
chr8_-_81923366 0.462 NM_008539
Smad1
MAD homolog 1 (Drosophila)
chr1_-_75207318 0.462 NM_029010
Glb1l
galactosidase, beta 1-like
chr12_-_76278318 0.456 NM_172805
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr3_-_146475652 0.453 NM_011100
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr6_+_30351902 0.452 NM_029742
Klhdc10
kelch domain containing 10
chr4_-_154010868 0.450 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr10_+_107599446 0.445 NM_027892
Ppp1r12a
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr11_+_75546384 0.438 NM_009536
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr14_-_47441795 0.437 NM_022023
Gmfb
glia maturation factor, beta
chr1_-_108610861 0.434 NM_009741
NM_177410
Bcl2

B-cell leukemia/lymphoma 2

chr5_+_144861227 0.434 NM_001081109
Lmtk2
lemur tyrosine kinase 2
chr1_+_141318927 0.433 NM_172643
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr15_+_6658368 0.426 NM_030168
Rictor
RPTOR independent companion of MTOR, complex 2
chr11_-_33063024 0.423 NM_008722
Npm1
nucleophosmin 1
chr1_-_51972816 0.422 NM_001161817
NM_010863
Myo1b

myosin IB

chr2_+_106535757 0.417 NM_029837
Mpped2
metallophosphoesterase domain containing 2
chr17_-_37088578 0.416 NM_029632
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr8_+_107749072 0.409 NM_145604
D230025D16Rik
RIKEN cDNA D230025D16 gene
chr4_-_45421590 0.405 NM_001009949
Mcart1
mitochondrial carrier triple repeat 1
chr13_-_104124527 0.404 NM_175171
Mast4
microtubule associated serine/threonine kinase family member 4
chr19_+_36908682 0.404 NM_001163635
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr3_-_146433200 0.403 NM_001164198
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chrX_+_103222548 0.400 NM_001109757
NM_009726
Atp7a

ATPase, Cu++ transporting, alpha polypeptide

chr4_-_3501912 0.399 NM_028097
Tmem68
transmembrane protein 68
chrX_+_97925185 0.398 NM_023608
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_-_3661578 0.395 NM_001011874
Xkr4
X Kell blood group precursor related family member 4
chr6_-_149050201 0.393 NM_177192
Dennd5b
DENN/MADD domain containing 5B
chr19_-_57271875 0.389 NM_001103177
Ablim1
actin-binding LIM protein 1
chr13_-_111070392 0.383 NM_023852
Rab3c
RAB3C, member RAS oncogene family
chr2_+_4322020 0.383 NM_001177843
Frmd4a
FERM domain containing 4A
chr9_-_53475610 0.382 NM_001161618
NM_027807
Cul5

cullin 5

chr8_+_48618988 0.380 NM_203507
Rwdd4a
RWD domain containing 4A
chr13_-_102538106 0.376 NM_001077495
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
11.59 1.11e-04 GO:0007409 axonogenesis
8.87 1.88e-04 GO:0031175 neuron projection development
10.57 2.23e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
10.10 3.14e-04 GO:0048812 neuron projection morphogenesis
6.11 3.95e-04 GO:0040011 locomotion
6.72 5.33e-04 GO:0030030 cell projection organization
15.20 7.28e-04 GO:0007411 axon guidance
8.36 1.28e-03 GO:0048858 cell projection morphogenesis
7.01 1.31e-03 GO:0048666 neuron development
8.33 1.32e-03 GO:0000904 cell morphogenesis involved in differentiation
8.19 1.48e-03 GO:0032990 cell part morphogenesis
6.76 1.76e-03 GO:0000902 cell morphogenesis
3.98 1.94e-03 GO:0007399 nervous system development
6.21 3.46e-03 GO:0032989 cellular component morphogenesis
4.76 4.27e-03 GO:0048699 generation of neurons
4.46 7.79e-03 GO:0022008 neurogenesis
5.57 8.25e-03 GO:0030182 neuron differentiation
7.40 4.27e-02 GO:0006935 chemotaxis
7.40 4.27e-02 GO:0042330 taxis

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.19 2.76e-04 GO:0042995 cell projection
5.67 6.22e-04 GO:0043005 neuron projection
2.19 5.36e-03 GO:0005886 plasma membrane
2.14 7.50e-03 GO:0071944 cell periphery

Nothing significant found in function category.