• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: YY1.p2

Z-value: 3.976

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr7_-_111001598	48.038	NM_008221	Hbb-y	hemoglobin Y, beta-like embryonic chain
chr7_-_110991602	22.722	NM_008219	Hbb-bh1	hemoglobin Z, beta-like embryonic chain
chr7_-_56892061	17.797	NM_001005232	Dbx1	developing brain homeobox 1
chr4_+_154335029	15.104	NM_010419	Hes5	hairy and enhancer of split 5 (Drosophila)
chr9_+_74709673	13.006	NM_008262	Onecut1	one cut domain, family member 1
chr9_+_64988960	12.252	NM_008988	Igdcc3	immunoglobulin superfamily, DCC subclass, member 3
chr5_-_38215607	11.819	NM_010835	Msx1	homeobox, msh-like 1
chr10_+_79317409	11.202		Ptbp1	polypyrimidine tract binding protein 1
chr11_+_23978029	10.718	NM_001159289 NM_016707	Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)
chr3_-_126701320	10.527		Ank2	ankyrin 2, brain
chr2_-_73613381	9.960	NM_001113246 NM_001166603	Chn1	chimerin (chimaerin) 1
chr14_-_104867215	9.681	NM_011143	Pou4f1	POU domain, class 4, transcription factor 1
chr7_+_30088984	9.577	NM_013874	Dpf1	D4, zinc and double PHD fingers family 1
chr5_-_67490295	8.809	NM_008888	Phox2b	paired-like homeobox 2b
chr4_-_43536296	8.512		Tpm2	tropomyosin 2, beta
chr6_-_83071206	8.447		Wbp1	WW domain binding protein 1
chr10_+_79144868	8.440	NM_177613	Cdc34	cell division cycle 34 homolog (S. cerevisiae)
chr16_-_22163035	8.318		Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2
chr11_+_23978110	8.235		Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)
chr13_+_23627286	8.138	NM_145073	Hist1h3g	histone cluster 1, H3g
chr11_+_32176599	8.113	NM_010405	Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex
chr14_-_69902984	7.811		Slc25a37	solute carrier family 25, member 37
chr2_+_13496013	7.796		Vim	vimentin
chr13_+_23844213	7.792	NM_178203	Hist1h3b	histone cluster 1, H3b
chr2_+_13495931	7.722	NM_011701	Vim	vimentin
chr18_+_67365012	7.698	NM_024190	Chmp1b	chromatin modifying protein 1B
chr16_+_55966458	7.665		Rpl24	ribosomal protein L24
chr19_-_41818111	7.662		Slit1	slit homolog 1 (Drosophila)
chr5_+_129526311	7.517		Ran	RAN, member RAS oncogene family
chr1_-_170361985	7.476		Pbx1	pre B-cell leukemia transcription factor 1
chr11_+_62366262	7.233		Ubb	ubiquitin B
chr1_+_182499091	7.128	NM_007415	Parp1	poly (ADP-ribose) polymerase family, member 1
chr14_-_19103447	7.107	NM_025586	Rpl15	ribosomal protein L15
chr6_-_38826156	7.082	NM_010433	Hipk2	homeodomain interacting protein kinase 2
chr13_-_23663006	7.069	NM_178187	Hist1h2ae	histone cluster 1, H2ae
chr3_+_145784635	7.050	NM_134160	Mcoln3	mucolipin 3
chr1_+_182499015	6.995		Parp1	poly (ADP-ribose) polymerase family, member 1
chr2_+_75670296	6.927		Agps	alkylglycerone phosphate synthase
chr18_-_6490828	6.901		Epc1	enhancer of polycomb homolog 1 (Drosophila)
chr11_-_50105794	6.844	NM_175334	Maml1	mastermind like 1 (Drosophila)
chr14_-_21000972	6.843	NM_021542	Kcnk5	potassium channel, subfamily K, member 5
chr2_-_179839111	6.773		Hrh3	histamine receptor H3
chr2_-_24775083	6.759	NM_001012518 NM_001109686 NM_001109687 NM_172545	Ehmt1	euchromatic histone methyltransferase 1
chr2_-_144096518	6.677		Snx5	sorting nexin 5
chr11_+_48613820	6.571	NM_008143	Gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr6_-_12699189	6.562	NM_001164805	Thsd7a	thrombospondin, type I, domain containing 7A
chr19_+_39005433	6.513	NM_008234	Hells	helicase, lymphoid specific
chr18_+_70727897	6.491	NM_010773	Mbd2	methyl-CpG binding domain protein 2
chr9_+_122860175	6.459	NM_010620	Kif15	kinesin family member 15
chr11_+_102465839	6.450		Fzd2	frizzled homolog 2 (Drosophila)
chr16_+_55966387	6.400	NM_024218	Rpl24	ribosomal protein L24
chr19_+_6363686	6.348	NM_001110791 NM_011750	Sf1	splicing factor 1
chr6_+_15135505	6.329	NM_212435	Foxp2	forkhead box P2
chr11_-_63735652	6.323	NM_018805	Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr7_+_16986478	6.244	NM_198631	Zc3h4	zinc finger CCCH-type containing 4
chr1_-_170361525	6.216		Pbx1	pre B-cell leukemia transcription factor 1
chr11_-_70468061	6.208		Pfn1	profilin 1
chr16_-_22163264	6.155	NM_183029	Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2
chr18_-_6490682	6.146		Epc1	enhancer of polycomb homolog 1 (Drosophila)
chr9_-_71743854	5.988		Tcf12	transcription factor 12
chr5_+_135663096	5.972	NM_011714	Baz1b	bromodomain adjacent to zinc finger domain, 1B
chr14_-_67691221	5.920	NM_028032	Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr12_-_47919695	5.859	NM_021361	Nova1	neuro-oncological ventral antigen 1
chr14_-_109313298	5.793		Slitrk1	SLIT and NTRK-like family, member 1
chr2_-_179777080	5.684	NM_011969	Psma7	proteasome (prosome, macropain) subunit, alpha type 7
chr4_+_41082861	5.668		Ube2r2	ubiquitin-conjugating enzyme E2R 2
chr2_-_44965603	5.540		Zeb2	zinc finger E-box binding homeobox 2
chr18_+_56867378	5.487	NM_010721	Lmnb1	lamin B1
chr12_-_28027272	5.484		Sox11	SRY-box containing gene 11
chr2_-_164705231	5.465		4930445K14Rik	RIKEN cDNA 4930445K14 gene
chr6_-_115626589	5.448	NM_029780	Raf1	v-raf-leukemia viral oncogene 1
chr11_+_44332878	5.378	NM_001166553	Rnf145	ring finger protein 145
chr12_+_53800369	5.378	NM_198111	Akap6	A kinase (PRKA) anchor protein 6
chr7_-_152125661	5.304		Ccnd1	cyclin D1
chr17_+_29169612	5.280		Srsf3	serine/arginine-rich splicing factor 3
chr13_-_21808011	5.258	NM_178199	Hist1h2bl	histone cluster 1, H2bl
chr6_+_47403899	5.249		Cul1	cullin 1
chr8_-_113370626	5.228	NM_133953	Sf3b3	splicing factor 3b, subunit 3
chr9_+_57351848	5.207	NM_133982	Rpp25	ribonuclease P 25 subunit (human)
chr1_+_42753970	5.193	NM_008900	Pou3f3	POU domain, class 3, transcription factor 3
chr13_+_23838602	5.084	NM_175664	Hist1h2bb	histone cluster 1, H2bb
chr7_-_110962416	5.075	NM_008220 NM_016956	Hbb-b1 Hbb-b2	hemoglobin, beta adult major chain hemoglobin, beta adult minor chain
chr7_+_52973440	5.071	NM_009077	Rpl18	ribosomal protein L18
chr2_-_132078887	5.068	NM_011045	Pcna	proliferating cell nuclear antigen
chr10_-_61246611	5.063	NM_207000	H2afy2	H2A histone family, member Y2
chr3_+_68808879	5.060	NM_133786	Smc4	structural maintenance of chromosomes 4
chr19_+_40969176	5.059	NM_028319	E130314M14Rik Zfp518a	RIKEN cDNA E130314M14 gene zinc finger protein 518A
chr14_+_35487052	5.049	NM_001004436	Wapal	wings apart-like homolog (Drosophila)
chr5_+_89194155	4.999		Dck	deoxycytidine kinase
chr13_-_104968472	4.991	NM_001093759 NM_001093760 NM_025879	2410002O22Rik	RIKEN cDNA 2410002O22 gene
chr2_+_13495963	4.982		Vim	vimentin
chr16_-_4719058	4.899	NM_026393	Nmral1	NmrA-like family domain containing 1
chr1_-_157882999	4.842		Tor1aip1	torsin A interacting protein 1
chr5_+_123794508	4.838		Bcl7a	B-cell CLL/lymphoma 7A
chr16_+_33056538	4.834	NM_001130485 NM_001130484 NM_021338	Rpl35a	ribosomal protein L35A
chr10_+_110910277	4.802		Nap1l1	nucleosome assembly protein 1-like 1
chr8_-_73905523	4.799		Nr2f6	nuclear receptor subfamily 2, group F, member 6
chr3_+_146162758	4.777	NM_010318	Gng5	guanine nucleotide binding protein (G protein), gamma 5
chr7_+_133630844	4.728	NM_001163713 NM_172745	Tufm	Tu translation elongation factor, mitochondrial
chr9_-_96378951	4.725	NM_011279	Rnf7	ring finger protein 7
chr7_-_88974235	4.711	NM_146193	Btbd1	BTB (POZ) domain containing 1
chr4_-_61869287	4.685		Zfp37	zinc finger protein 37
chr3_+_151873407	4.672	NM_057172	Fubp1	far upstream element (FUSE) binding protein 1
chr2_+_84680479	4.669	NM_024497	Slc43a1	solute carrier family 43, member 1
chr1_+_131170034	4.652		Thsd7b	thrombospondin, type I, domain containing 7B
chr11_-_97048933	4.643		Kpnb1	karyopherin (importin) beta 1
chr3_-_151873242	4.639	NM_027287	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_-_121261237	4.623		Rras2	related RAS viral (r-ras) oncogene homolog 2
chr11_-_97049143	4.622		Kpnb1	karyopherin (importin) beta 1
chr15_+_98620287	4.615	NM_021279	Wnt1	wingless-related MMTV integration site 1
chr10_-_93052348	4.601	NM_027246	Snrpf	small nuclear ribonucleoprotein polypeptide F
chr13_+_23663264	4.554	NM_178196	Hist1h2bg	histone cluster 1, H2bg
chr13_-_22134795	4.547	NM_178186	Hist1h2ag Hist1h2ai	histone cluster 1, H2ag histone cluster 1, H2ai
chr16_-_33056255	4.515	NM_178378	Iqcg	IQ motif containing G
chr11_-_70468130	4.510	NM_011072	Pfn1	profilin 1
chr2_+_75497282	4.499	NM_053263 NM_146130 NM_198090	Hnrnpa3 Gm6793	heterogeneous nuclear ribonucleoprotein A3 heterogeneous nuclear ribonucleoprotein A3 pseudogene
chr14_-_47407948	4.494	NM_009919	Cnih	cornichon homolog (Drosophila)
chr19_+_41557475	4.484		Lcor	ligand dependent nuclear receptor corepressor
chr12_-_102321835	4.472		Smek1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr13_+_21813912	4.463	NM_178200	Hist1h2bm	histone cluster 1, H2bm
chr13_-_23677831	4.446		Hist1h2be	histone cluster 1, H2be
chr14_-_55236828	4.418	NM_011186	Psmb5	proteasome (prosome, macropain) subunit, beta type 5
chr10_-_39977451	4.414	NM_026113	Gtf3c6	general transcription factor IIIC, polypeptide 6, alpha
chrX_-_71212314	4.391		Hcfc1	host cell factor C1
chr1_-_93295259	4.385		Ilkap	integrin-linked kinase-associated serine/threonine phosphatase 2C
chr8_+_107821562	4.355	NM_148952	E2f4	E2F transcription factor 4
chr11_+_44332426	4.335	NM_028862	Rnf145	ring finger protein 145
chr13_+_21808259	4.324	NM_178182	Hist1h2ai	histone cluster 1, H2ai
chr8_+_108384479	4.318	NM_026532	Nutf2	nuclear transport factor 2
chr11_+_75492764	4.283	NM_133656	Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)
chr7_-_34953455	4.266	NM_016682	Uba2	ubiquitin-like modifier activating enzyme 2
chr11_-_120852554	4.244		Csnk1d	casein kinase 1, delta
chr2_+_136717938	4.241	NM_028834	2210009G21Rik	RIKEN cDNA 2210009G21 gene
chr2_-_63936044	4.234	NM_021716	Fign	fidgetin
chr13_-_3917356	4.229	NM_019671	Net1	neuroepithelial cell transforming gene 1
chr4_-_116300068	4.176	NM_001081475	Nasp	nuclear autoantigenic sperm protein (histone-binding)
chr11_-_120459646	4.173	NM_011568	Thoc4	THO complex 4
chr5_+_129526060	4.171		Ran	RAN, member RAS oncogene family
chr11_-_69182891	4.166	NM_146019	Chd3	chromodomain helicase DNA binding protein 3
chr2_+_29725034	4.162		Cercam	cerebral endothelial cell adhesion molecule
chr15_-_75751888	4.150	NM_025412	Pycrl	pyrroline-5-carboxylate reductase-like
chr3_+_101814059	4.134	NM_178777	Nhlh2	nescient helix loop helix 2
chr13_-_99696254	4.114	NM_178716	Tnpo1	transportin 1
chr4_+_125781197	4.106	NM_001145827 NM_028800	Stk40	serine/threonine kinase 40
chr6_+_64679118	4.096	NM_007500	Atoh1	atonal homolog 1 (Drosophila)
chr11_-_29447830	4.075	NM_001033865 NM_024277	Rps27a	ribosomal protein S27A
chr13_+_22135065	4.072	NM_178198	Hist1h2bj	histone cluster 1, H2bj
chr17_-_23965968	4.037	NM_026305	Tceb2	transcription elongation factor B (SIII), polypeptide 2
chr16_-_16560240	4.008	NM_139232 NM_139234	Fgd4	FYVE, RhoGEF and PH domain containing 4
chr5_+_93522440	4.008	NM_001009818	Sept11	septin 11
chr2_-_140497183	4.000		Flrt3	fibronectin leucine rich transmembrane protein 3
chr11_-_70468019	4.000		Pfn1	profilin 1
chr3_+_127336055	3.999	NM_009718	Neurog2	neurogenin 2
chr11_+_102465684	3.987	NM_020510	Fzd2	frizzled homolog 2 (Drosophila)
chr2_+_29643739	3.984	NM_178693	Coq4	coenzyme Q4 homolog (yeast)
chr4_-_155571450	3.983		Agrn	agrin
chr6_+_47827641	3.982		Zfp282	zinc finger protein 282
chr12_+_16817741	3.974		E2f6	E2F transcription factor 6
chr19_+_4962305	3.946	NM_025553	Mrpl11	mitochondrial ribosomal protein L11
chr3_+_95976435	3.943	NM_153053	Sf3b4	splicing factor 3b, subunit 4
chr13_-_21845695	3.928	NM_178183	Hist1h2ak	histone cluster 1, H2ak
chr11_+_72420705	3.896	NM_025985	Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
chr12_-_29320801	3.859	NM_011300	Rps7	ribosomal protein S7
chr9_+_44412931	3.847	NM_001110826 NM_007841 NM_181324	Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr2_-_70663453	3.839	NM_172664	Tlk1	tousled-like kinase 1
chr11_+_69809250	3.833	NM_030064	Phf23	PHD finger protein 23
chr4_+_147415297	3.832	NM_001161798	Mthfr	5,10-methylenetetrahydrofolate reductase
chr11_-_95867076	3.830	NM_009951	Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1
chr2_-_156005873	3.798	NM_133242	Rbm39	RNA binding motif protein 39
chr19_+_30105077	3.787		Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2
chr6_-_127100954	3.776	NM_009829	Ccnd2	cyclin D2
chr4_-_61869471	3.776		Zfp37	zinc finger protein 37
chr4_+_41082993	3.756	NM_026275	Ube2r2	ubiquitin-conjugating enzyme E2R 2
chr4_-_123427465	3.752	NM_023423	Akirin1	akirin 1
chr1_+_173259513	3.746		Dedd	death effector domain-containing
chr6_+_38331516	3.735	NM_153600	Ttc26	tetratricopeptide repeat domain 26
chr9_-_37421173	3.735	NM_011449	Spa17	sperm autoantigenic protein 17
chr2_-_25066706	3.724	NM_021393	Cobra1	cofactor of BRCA1
chr11_+_51781124	3.712	NM_029976	Cdkn2aipnl	CDKN2A interacting protein N-terminal like
chr4_-_129012489	3.711		Rbbp4	retinoblastoma binding protein 4
chr8_-_127386864	3.702	NM_025615	2810004N23Rik	RIKEN cDNA 2810004N23 gene
chr7_+_134614507	3.695		Prr14	proline rich 14
chr3_+_32635988	3.687		Ndufb5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr7_+_66484094	3.670	NM_173010 NM_001033962 NM_011668	Ube3a	ubiquitin protein ligase E3A
chr2_+_75670230	3.657	NM_172666	Agps	alkylglycerone phosphate synthase
chr14_+_25309938	3.643		Rps24	ribosomal protein S24
chr4_+_43071852	3.640	NM_001081413 NM_021468	Unc13b	unc-13 homolog B (C. elegans)
chr3_+_14578670	3.635	NM_007892	E2f5	E2F transcription factor 5
chr9_-_69608633	3.634	NM_022378	Foxb1	forkhead box B1
chr14_-_58283787	3.633	NM_020506	Xpo4	exportin 4
chr9_-_108469265	3.616		Ndufaf3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr7_-_52147751	3.609		Med25	mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr12_+_16817772	3.596		E2f6	E2F transcription factor 6
chr9_-_44042043	3.586	NM_007619	Cbl	Casitas B-lineage lymphoma
chr5_-_134790544	3.575	NM_001080746 NM_001080747 NM_001080748 NM_001080749 NM_010365	Gtf2i	general transcription factor II I
chr1_+_74552794	3.566		Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr10_-_62486581	3.562	NM_001079824	Hnrnph3 D10Bwg1070e	heterogeneous nuclear ribonucleoprotein H3 DNA segment, Chr 10, Brigham & Women's Genetics 1070 expressed
chr5_+_73305509	3.526	NM_001113423 NM_153567	Slain2	SLAIN motif family, member 2
chr6_+_125045998	3.525	NM_145979	Chd4	chromodomain helicase DNA binding protein 4
chr3_-_58329780	3.518	NM_030685	Serp1	stress-associated endoplasmic reticulum protein 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.94	1.49e-50	GO:0044260	cellular macromolecule metabolic process
2.40	4.23e-49	GO:0010467	gene expression
1.78	4.24e-41	GO:0043170	macromolecule metabolic process
2.30	5.80e-38	GO:0016070	RNA metabolic process
2.18	2.30e-37	GO:0090304	nucleic acid metabolic process
2.25	2.15e-36	GO:0034645	cellular macromolecule biosynthetic process
2.24	3.42e-36	GO:0009059	macromolecule biosynthetic process
1.63	4.43e-36	GO:0044237	cellular metabolic process
2.02	2.31e-35	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58	2.74e-31	GO:0044238	primary metabolic process
1.95	4.52e-29	GO:0044249	cellular biosynthetic process
1.86	1.13e-28	GO:0034641	cellular nitrogen compound metabolic process
1.83	6.09e-28	GO:0006807	nitrogen compound metabolic process
1.91	6.70e-28	GO:0009058	biosynthetic process
1.85	3.85e-27	GO:0060255	regulation of macromolecule metabolic process
1.99	1.03e-26	GO:0010468	regulation of gene expression
1.82	3.41e-26	GO:0080090	regulation of primary metabolic process
1.81	5.61e-26	GO:0031323	regulation of cellular metabolic process
2.04	4.65e-25	GO:0051252	regulation of RNA metabolic process
1.99	1.02e-24	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.46	2.29e-24	GO:0008152	metabolic process
1.96	7.63e-24	GO:0010556	regulation of macromolecule biosynthetic process
1.69	3.13e-22	GO:0019222	regulation of metabolic process
1.99	5.36e-22	GO:0006355	regulation of transcription, DNA-dependent
1.88	9.83e-22	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86	4.60e-21	GO:0051171	regulation of nitrogen compound metabolic process
1.86	5.93e-21	GO:0031326	regulation of cellular biosynthetic process
1.85	1.67e-20	GO:0009889	regulation of biosynthetic process
2.11	8.00e-20	GO:0006351	transcription, DNA-dependent
2.11	9.86e-20	GO:0032774	RNA biosynthetic process
7.48	9.16e-19	GO:0006414	translational elongation
4.07	2.43e-17	GO:0006412	translation
2.58	6.03e-16	GO:0007049	cell cycle
2.99	1.87e-15	GO:0006396	RNA processing
1.82	1.16e-14	GO:0071841	cellular component organization or biogenesis at cellular level
1.79	3.47e-13	GO:0044267	cellular protein metabolic process
3.65	1.26e-12	GO:0008380	RNA splicing
3.12	6.74e-12	GO:0006325	chromatin organization
1.77	6.83e-12	GO:0071842	cellular component organization at cellular level
2.21	1.09e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
3.31	2.47e-11	GO:0034621	cellular macromolecular complex subunit organization
2.60	3.23e-11	GO:0022402	cell cycle process
2.73	5.00e-11	GO:0051276	chromosome organization
1.59	9.56e-11	GO:0071840	cellular component organization or biogenesis
3.07	1.96e-10	GO:0016071	mRNA metabolic process
1.91	3.25e-10	GO:0006996	organelle organization
1.19	6.41e-10	GO:0009987	cellular process
2.10	9.55e-10	GO:0010605	negative regulation of macromolecule metabolic process
2.86	2.20e-09	GO:0000278	mitotic cell cycle
3.19	2.92e-09	GO:0006397	mRNA processing
3.24	2.94e-09	GO:0034622	cellular macromolecular complex assembly
2.06	4.10e-09	GO:0044085	cellular component biogenesis
2.45	7.42e-09	GO:0071844	cellular component assembly at cellular level
1.55	1.30e-08	GO:0016043	cellular component organization
2.03	2.26e-08	GO:0031324	negative regulation of cellular metabolic process
1.56	4.58e-08	GO:0019538	protein metabolic process
1.96	5.16e-08	GO:0009892	negative regulation of metabolic process
2.31	5.31e-08	GO:0051253	negative regulation of RNA metabolic process
2.32	6.91e-08	GO:0045892	negative regulation of transcription, DNA-dependent
1.84	1.36e-07	GO:0010604	positive regulation of macromolecule metabolic process
5.92	3.19e-07	GO:0071824	protein-DNA complex subunit organization
2.16	4.70e-07	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.14	5.14e-07	GO:0010558	negative regulation of macromolecule biosynthetic process
5.74	5.96e-07	GO:0006333	chromatin assembly or disassembly
2.16	6.58e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.20	8.70e-07	GO:0043933	macromolecular complex subunit organization
2.74	1.01e-06	GO:0016568	chromatin modification
5.90	1.04e-06	GO:0065004	protein-DNA complex assembly
2.00	1.15e-06	GO:0022607	cellular component assembly
2.15	1.21e-06	GO:0010629	negative regulation of gene expression
2.13	1.31e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.75	1.34e-06	GO:0009893	positive regulation of metabolic process
2.04	3.00e-06	GO:0009890	negative regulation of biosynthetic process
1.76	3.47e-06	GO:0031325	positive regulation of cellular metabolic process
2.04	5.44e-06	GO:0031327	negative regulation of cellular biosynthetic process
5.67	6.26e-06	GO:0034728	nucleosome organization
2.41	7.77e-06	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
4.54	8.06e-06	GO:0031397	negative regulation of protein ubiquitination
2.80	1.18e-05	GO:0006511	ubiquitin-dependent protein catabolic process
2.16	1.60e-05	GO:0065003	macromolecular complex assembly
2.72	1.80e-05	GO:0051603	proteolysis involved in cellular protein catabolic process
1.54	2.00e-05	GO:0048523	negative regulation of cellular process
2.74	2.24e-05	GO:0019941	modification-dependent protein catabolic process
2.72	2.75e-05	GO:0043632	modification-dependent macromolecule catabolic process
2.54	2.77e-05	GO:0007420	brain development
2.67	2.99e-05	GO:0044257	cellular protein catabolic process
5.43	3.62e-05	GO:0031497	chromatin assembly
4.82	3.74e-05	GO:0051352	negative regulation of ligase activity
4.82	3.74e-05	GO:0051444	negative regulation of ubiquitin-protein ligase activity
5.71	4.87e-05	GO:0006334	nucleosome assembly
2.49	6.67e-05	GO:0051301	cell division
4.18	8.44e-05	GO:0051438	regulation of ubiquitin-protein ligase activity
1.86	9.06e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
4.83	9.18e-05	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.34	1.15e-04	GO:0031396	regulation of protein ubiquitination
4.50	1.18e-04	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.09	1.24e-04	GO:0051340	regulation of ligase activity
2.71	1.68e-04	GO:0010608	posttranscriptional regulation of gene expression
4.62	1.85e-04	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.47	1.90e-04	GO:0048519	negative regulation of biological process
4.15	2.04e-04	GO:0006323	DNA packaging
2.25	2.14e-04	GO:0022403	cell cycle phase
2.48	2.37e-04	GO:0030163	protein catabolic process
1.90	2.72e-04	GO:0045893	positive regulation of transcription, DNA-dependent
2.23	3.74e-04	GO:0044265	cellular macromolecule catabolic process
3.66	4.30e-04	GO:0071103	DNA conformation change
1.87	4.89e-04	GO:0051254	positive regulation of RNA metabolic process
1.39	6.89e-04	GO:0007275	multicellular organismal development
2.89	8.18e-04	GO:0022613	ribonucleoprotein complex biogenesis
1.81	8.99e-04	GO:0010628	positive regulation of gene expression
1.75	9.77e-04	GO:0031328	positive regulation of cellular biosynthetic process
2.15	1.09e-03	GO:0007417	central nervous system development
1.74	1.15e-03	GO:0009891	positive regulation of biosynthetic process
2.15	1.32e-03	GO:0051247	positive regulation of protein metabolic process
4.29	1.32e-03	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.98	1.40e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.36	1.49e-03	GO:0032502	developmental process
1.77	1.64e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.75	2.44e-03	GO:0071843	cellular component biogenesis at cellular level
2.02	3.74e-03	GO:0009057	macromolecule catabolic process
3.04	3.74e-03	GO:0010498	proteasomal protein catabolic process
3.04	3.74e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.86	4.11e-03	GO:0031400	negative regulation of protein modification process
1.73	4.27e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
2.73	6.38e-03	GO:0034470	ncRNA processing
2.51	6.66e-03	GO:0034660	ncRNA metabolic process
3.80	7.14e-03	GO:0051443	positive regulation of ubiquitin-protein ligase activity
3.71	1.00e-02	GO:0051351	positive regulation of ligase activity
1.60	1.01e-02	GO:0007399	nervous system development
1.38	1.17e-02	GO:0048522	positive regulation of cellular process
3.23	1.18e-02	GO:0031398	positive regulation of protein ubiquitination
2.06	1.24e-02	GO:0032270	positive regulation of cellular protein metabolic process
2.46	1.45e-02	GO:0000087	M phase of mitotic cell cycle
10.37	1.60e-02	GO:0042273	ribosomal large subunit biogenesis
2.42	2.06e-02	GO:0048285	organelle fission
1.35	2.17e-02	GO:0048856	anatomical structure development
5.90	2.39e-02	GO:0070936	protein K48-linked ubiquitination
2.43	2.64e-02	GO:0000280	nuclear division
2.43	2.64e-02	GO:0007067	mitosis
2.28	3.54e-02	GO:0051248	negative regulation of protein metabolic process
1.59	4.30e-02	GO:0051246	regulation of protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.04	2.84e-68	GO:0005634	nucleus
1.48	4.07e-59	GO:0044424	intracellular part
1.46	1.44e-57	GO:0005622	intracellular
1.52	9.58e-50	GO:0043229	intracellular organelle
1.52	3.43e-49	GO:0043226	organelle
1.56	2.16e-46	GO:0043227	membrane-bounded organelle
1.56	2.42e-46	GO:0043231	intracellular membrane-bounded organelle
2.48	3.52e-36	GO:0044428	nuclear part
1.98	2.85e-35	GO:0032991	macromolecular complex
1.79	5.11e-31	GO:0044446	intracellular organelle part
1.76	3.21e-29	GO:0044422	organelle part
2.34	6.09e-29	GO:0031974	membrane-enclosed lumen
2.48	1.84e-28	GO:0031981	nuclear lumen
2.35	2.07e-28	GO:0070013	intracellular organelle lumen
2.35	2.66e-28	GO:0043233	organelle lumen
2.72	4.10e-25	GO:0005654	nucleoplasm
1.79	1.21e-18	GO:0043234	protein complex
2.72	2.95e-16	GO:0044451	nucleoplasm part
3.05	2.21e-15	GO:0030529	ribonucleoprotein complex
1.15	3.14e-14	GO:0005623	cell
1.15	3.14e-14	GO:0044464	cell part
1.74	7.78e-14	GO:0043228	non-membrane-bounded organelle
1.74	7.78e-14	GO:0043232	intracellular non-membrane-bounded organelle
1.31	3.25e-13	GO:0005737	cytoplasm
1.74	1.05e-07	GO:0005829	cytosol
2.51	1.59e-07	GO:0044427	chromosomal part
3.49	3.36e-07	GO:0005840	ribosome
2.74	3.87e-07	GO:0005667	transcription factor complex
2.40	3.88e-07	GO:0005694	chromosome
3.69	2.19e-06	GO:0005681	spliceosomal complex
4.39	2.94e-05	GO:0032993	protein-DNA complex
4.04	2.35e-04	GO:0071013	catalytic step 2 spliceosome
5.05	3.31e-04	GO:0000786	nucleosome
4.51	5.55e-04	GO:0034708	methyltransferase complex
4.51	5.55e-04	GO:0035097	histone methyltransferase complex
2.18	5.97e-04	GO:0005730	nucleolus
3.10	7.19e-04	GO:0000775	chromosome, centromeric region
3.76	1.38e-03	GO:0016585	chromatin remodeling complex
3.12	3.25e-03	GO:0044445	cytosolic part
4.45	8.31e-03	GO:0022626	cytosolic ribosome
8.78	8.84e-03	GO:0016581	NuRD complex
5.35	9.44e-03	GO:0008287	protein serine/threonine phosphatase complex
15.21	1.24e-02	GO:0005833	hemoglobin complex
1.79	1.24e-02	GO:0015630	microtubule cytoskeleton
1.21	1.35e-02	GO:0044444	cytoplasmic part
2.36	1.51e-02	GO:0000785	chromatin
3.87	1.61e-02	GO:0000502	proteasome complex
4.89	2.06e-02	GO:0015934	large ribosomal subunit
4.50	4.13e-02	GO:0000118	histone deacetylase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.19	2.19e-37	GO:0003676	nucleic acid binding
3.13	2.85e-25	GO:0003723	RNA binding
1.28	9.07e-19	GO:0005488	binding
1.98	2.05e-16	GO:0003677	DNA binding
1.33	1.97e-08	GO:0005515	protein binding
4.39	2.58e-08	GO:0003735	structural constituent of ribosome
1.99	8.06e-08	GO:0030528	transcription regulator activity
3.19	8.93e-07	GO:0003682	chromatin binding
4.32	1.06e-05	GO:0003729	mRNA binding
4.09	2.84e-05	GO:0008135	translation factor activity, nucleic acid binding
1.48	1.22e-04	GO:0000166	nucleotide binding
2.40	1.80e-04	GO:0008134	transcription factor binding
2.22	2.33e-04	GO:0005198	structural molecule activity
1.59	4.06e-04	GO:0008270	zinc ion binding
1.89	4.11e-04	GO:0043565	sequence-specific DNA binding
2.50	1.19e-03	GO:0003712	transcription cofactor activity
2.49	1.31e-03	GO:0000989	transcription factor binding transcription factor activity
2.46	1.70e-03	GO:0000988	protein binding transcription factor activity
2.25	1.72e-03	GO:0016564	transcription repressor activity
1.74	3.36e-03	GO:0001071	nucleic acid binding transcription factor activity
1.74	3.36e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.45	1.13e-02	GO:0046914	transition metal ion binding
2.39	2.32e-02	GO:0043566	structure-specific DNA binding
6.34	3.16e-02	GO:0003730	mRNA 3'-UTR binding
1.60	4.10e-02	GO:0019899	enzyme binding