Motif ID: ZIC1..3.p2

Z-value: 1.477

Transcription factors associated with ZIC1..3.p2:

NameEntrezDescription
Zic1 22771 zinc finger protein of the cerebellum 1
Zic2 22772 zinc finger protein of the cerebellum 2
Zic3 22773 zinc finger protein of the cerebellum 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Zic1chr9_-_912606190.873.8e-12Click!
Zic3chrX_+_55283804-0.805.4e-09Click!
Zic2chr14_+_1228745980.774.0e-08Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr17_+_37187550 18.830 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_116515361 11.743 Cygb
cytoglobin
chr3_+_31048841 10.232 NM_008770
Cldn11
claudin 11
chr6_-_125444722 9.864 NM_007657
Cd9
CD9 antigen
chr16_+_91270009 9.181 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr14_+_14117313 8.699 Synpr
synaptoporin
chr6_-_126114938 7.731 NM_001164035
Ntf3
neurotrophin 3
chr14_-_102007883 7.233 Tbc1d4
TBC1 domain family, member 4
chr10_+_60638341 7.019 Tbata
thymus, brain and testes associated
chr1_-_137064124 6.870 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr5_+_37259780 6.835 NM_172994
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr11_-_116515232 6.719 Cygb
cytoglobin
chr10_-_63552994 6.707 NM_178678
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_49508472 6.442 NM_001111268
NM_010349
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr10_-_126778941 6.429 Gli1
GLI-Kruppel family member GLI1
chr14_+_14117292 6.409 NM_028052
Synpr
synaptoporin
chr19_-_5085487 6.255 Tmem151a
transmembrane protein 151A
chr19_+_4711207 6.242 Spnb3
spectrin beta 3
chr9_-_54509453 6.222 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr6_-_115201866 5.972 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr17_+_27792487 5.897 Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr4_+_144482979 5.373 NM_011303
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_-_98190774 5.370 NM_010895
Neurod2
neurogenic differentiation 2
chr11_-_41995688 5.313 Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr14_+_70930491 5.048 NM_145219
Lgi3
leucine-rich repeat LGI family, member 3
chr4_-_70195870 5.001 Megf9
multiple EGF-like-domains 9
chr2_-_32208737 4.960 NM_010065
Dnm1
dynamin 1
chr11_+_61298923 4.917 NM_029568
Mfap4
microfibrillar-associated protein 4
chr8_-_89996089 4.777 Cbln1
cerebellin 1 precursor protein
chr13_+_54472833 4.766 Cplx2
complexin 2
chr7_-_149843316 4.764 NM_001122737
Igf2
insulin-like growth factor 2
chr17_-_24826873 4.736 NM_011522
Syngr3
synaptogyrin 3
chr3_-_117063090 4.647 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr12_+_77505356 4.625 NM_008301
Hspa2
heat shock protein 2
chr6_-_115201846 4.615 Timp4
tissue inhibitor of metalloproteinase 4
chr16_-_85803343 4.495 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr13_+_54472806 4.401 Cplx2
complexin 2
chr15_+_40486630 4.314 Zfpm2
zinc finger protein, multitype 2
chr11_+_87574041 4.310 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chr9_+_43851477 4.253 Thy1
thymus cell antigen 1, theta
chr16_+_18776936 4.193 NM_013805
Cldn5
claudin 5
chr17_-_45686604 4.175 NM_001013749
Tmem151b
transmembrane protein 151B
chr6_+_108163089 4.138 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr19_+_4711220 4.031 NM_021287
Spnb3
spectrin beta 3
chr13_-_54712629 4.025 NM_028870
Cltb
clathrin, light polypeptide (Lcb)
chrX_+_158154967 4.007 NM_001103367
Rai2
retinoic acid induced 2
chr5_+_37259906 3.928 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr17_+_37187984 3.923 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_+_136333083 3.895 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr13_+_54472705 3.874 NM_009946
Cplx2
complexin 2
chr16_-_20621287 3.862 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_125165597 3.808 NM_001080557
NM_009496
Vamp1

vesicle-associated membrane protein 1

chr4_+_119406384 3.769 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr4_-_68615382 3.671 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr15_-_8584897 3.662 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_148578716 3.649 NM_001114664
Iqsec2
IQ motif and Sec7 domain 2
chr8_-_89996474 3.643 NM_019626
Cbln1
cerebellin 1 precursor protein
chr4_-_128798481 3.612 NM_010471
Hpca
hippocalcin
chr9_+_50560862 3.595 NM_009964
Cryab
crystallin, alpha B
chr18_-_38760921 3.507 NM_011898
Spry4
sprouty homolog 4 (Drosophila)
chr6_+_124959207 3.487 Zfp384
zinc finger protein 384
chr10_+_85763294 3.463 Timp3
tissue inhibitor of metalloproteinase 3
chr17_+_25707771 3.458 2810468N07Rik
RIKEN cDNA 2810468N07 gene
chr14_-_14117143 3.453 NM_177813
Gm5087
predicted gene 5087
chr7_-_119301920 3.418 Dkk3
dickkopf homolog 3 (Xenopus laevis)
chr16_-_85803359 3.410 NM_009621
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr5_+_43625165 3.400 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr10_-_128356215 3.390 NM_134006
Rdh5
retinol dehydrogenase 5
chr2_-_180891448 3.292 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr2_+_35137898 3.291 NM_146120
Gsn
gelsolin
chr15_+_88692885 3.281 Pim3
proviral integration site 3
chr2_+_158492854 3.280 NM_001159662
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr18_+_86564229 3.255 NM_144946
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr6_-_126594802 3.241 Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr4_+_126698539 3.238 NM_023603
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr7_+_3303657 3.226 NM_011102
Prkcc
protein kinase C, gamma
chr11_+_68902025 3.202 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr11_-_116515602 3.180 NM_030206
Cygb
cytoglobin
chr5_+_72091188 3.158 NM_008069
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr12_-_25780932 3.118 NM_010496
Id2
inhibitor of DNA binding 2
chr15_-_53733989 3.083 NM_177225
Samd12
sterile alpha motif domain containing 12
chr2_-_92274110 3.080 NM_001113333
NM_009963
Cry2

cryptochrome 2 (photolyase-like)

chr4_-_58566053 3.074 NM_172989
Lpar1
lysophosphatidic acid receptor 1
chr2_+_156301543 3.016 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr17_-_24826812 3.007 Syngr3
synaptogyrin 3
chr9_-_56265833 2.973 NM_172924
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr6_+_121160693 2.936 NM_017379
Tuba8
tubulin, alpha 8
chr8_-_108489925 2.901 NM_009195
Slc12a4
solute carrier family 12, member 4
chr18_+_37966017 2.883 NM_033581
Pcdhgc3
protocadherin gamma subfamily C, 3
chr2_-_93797176 2.877 NM_001145034
Gm13889
predicted gene 13889
chr10_+_59568976 2.873 NM_052994
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr6_-_137597775 2.868 Eps8
epidermal growth factor receptor pathway substrate 8
chrX_+_70748418 2.867 NM_177236
Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
chr5_+_36100547 2.855 Ablim2
actin-binding LIM protein 2
chr13_+_55050729 2.844 NM_153131
Unc5a
unc-5 homolog A (C. elegans)
chr10_+_59569052 2.822 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr10_+_122116066 2.815 Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr1_+_60466462 2.811 NM_001198570
NM_001198571
NM_198127
Abi2


abl-interactor 2


chr15_+_79921725 2.794 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr4_-_68615283 2.791 Dbc1
deleted in bladder cancer 1 (human)
chr3_-_107320881 2.790 NM_172271
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr11_+_68901989 2.786 Vamp2
vesicle-associated membrane protein 2
chr16_-_85173978 2.764 App
amyloid beta (A4) precursor protein
chr4_-_150482562 2.737 Camta1
calmodulin binding transcription activator 1
chr18_+_58038278 2.723 NM_009194
Slc12a2
solute carrier family 12, member 2
chr4_-_136512727 2.706 NM_007939
Epha8
Eph receptor A8
chr1_-_136131399 2.662 Adora1
adenosine A1 receptor
chr6_+_86145220 2.654 NM_031199
Tgfa
transforming growth factor alpha
chr11_+_92959670 2.642 Car10
carbonic anhydrase 10
chr17_+_37182986 2.615 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr3_+_117278144 2.589 NM_029425
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr6_+_124946723 2.589 NM_175696
C530028O21Rik
RIKEN cDNA C530028O21 gene
chr2_+_61884596 2.552 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr3_+_28162135 2.551 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr18_+_64425037 2.542 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr15_-_94234549 2.536 Adamts20
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
chr8_+_86939262 2.516 NM_007578
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr9_+_43851466 2.516 NM_009382
Thy1
thymus cell antigen 1, theta
chr11_+_101107726 2.496 Ramp2
receptor (calcitonin) activity modifying protein 2
chr4_-_66065499 2.484 NM_019514
NM_207109
Astn2

astrotactin 2

chr7_+_26052714 2.483 Cic
capicua homolog (Drosophila)
chrX_+_98494487 2.465 NM_172932
Nlgn3
neuroligin 3
chr11_-_118947424 2.463 NM_007625
Cbx4
chromobox homolog 4 (Drosophila Pc class)
chr16_-_85173944 2.460 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr11_-_61307598 2.458 NM_011841
Mapk7
mitogen-activated protein kinase 7
chr4_+_119406425 2.453 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr2_+_55289530 2.438 NM_008426
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_+_17954324 2.434 NM_021560
Bhlhe22
basic helix-loop-helix family, member e22
chr15_-_95359136 2.433 NM_016743
Nell2
NEL-like 2 (chicken)
chrX_+_10294707 2.432 Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr12_+_45429913 2.428 Nrcam
neuron-glia-CAM-related cell adhesion molecule
chr10_-_126778634 2.405 NM_010296
Gli1
GLI-Kruppel family member GLI1
chrX_-_156576312 2.399 Pdha1
pyruvate dehydrogenase E1 alpha 1
chr9_-_91259829 2.393 Zic1
zinc finger protein of the cerebellum 1
chr17_+_81343933 2.392 NM_026516
Tmem178
transmembrane protein 178
chr9_+_45714587 2.382 NM_008794
Pcsk7
Rnf214
proprotein convertase subtilisin/kexin type 7
ring finger protein 214
chr10_+_105907394 2.364 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr6_-_119280616 2.355 NM_172492
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr9_-_107134182 2.353 NM_153413
Dock3
dedicator of cyto-kinesis 3
chr5_+_150214363 2.330 NM_027519
6330406I15Rik
RIKEN cDNA 6330406I15 gene
chr2_-_90420626 2.304 NM_008982
Ptprj
protein tyrosine phosphatase, receptor type, J
chr8_+_74135114 2.302 Glt25d1
glycosyltransferase 25 domain containing 1
chr5_+_22252006 2.294 NM_001081231
NM_029990
Lhfpl3

lipoma HMGIC fusion partner-like 3

chr11_+_70460758 2.283 Rnf167
ring finger protein 167
chr1_-_167390568 2.275 NM_028759
Dcaf6
DDB1 and CUL4 associated factor 6
chr6_+_134870680 2.271 Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr19_+_28909559 2.270 NM_009199
Slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr6_-_124867732 2.268


chr15_-_103170514 2.251 NM_013866
Zfp385a
zinc finger protein 385A
chr11_-_30168153 2.239 Spnb2
spectrin beta 2
chr8_-_42127242 2.227 NM_001005865
Mtus1
mitochondrial tumor suppressor 1
chr2_-_147011990 2.223 NM_001077632
NM_010919
Nkx2-2

NK2 transcription factor related, locus 2 (Drosophila)

chr6_-_115944822 2.221 NM_026376
Plxnd1
plexin D1
chrX_-_9240025 2.214 NM_025975
Dynlt3
dynein light chain Tctex-type 3
chr10_-_127057998 2.175 Lrp1
low density lipoprotein receptor-related protein 1
chr19_+_46471385 2.162 NM_001025391
NM_015752
Sufu

suppressor of fused homolog (Drosophila)

chr15_+_78858900 2.156 H1f0
H1 histone family, member 0
chr10_-_67011689 2.139 NM_001005419
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr19_-_8797529 2.137 Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_+_5008311 2.092 NM_146178
Ccdc106
coiled-coil domain containing 106
chr8_+_86423968 2.086 NM_181039
Lphn1
latrophilin 1
chr3_+_84756090 2.082 NM_080428
Fbxw7
F-box and WD-40 domain protein 7
chr2_+_90725895 2.077 NM_026161
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr3_+_88168495 2.056 NM_198410
Paqr6
progestin and adipoQ receptor family member VI
chr19_+_5741862 2.052 Ltbp3
latent transforming growth factor beta binding protein 3
chr3_+_96361879 2.046 NM_001009935
NM_023719
Txnip

thioredoxin interacting protein

chr5_+_43625194 2.039 Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr11_-_100800603 2.037 NM_011486
NM_213659
NM_213660
Stat3


signal transducer and activator of transcription 3


chr2_+_121121189 2.037 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr3_+_136333670 2.036 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_+_90097105 2.027 Gatad2b
GATA zinc finger domain containing 2B
chr15_-_81791230 2.010 NM_013872
Pmm1
phosphomannomutase 1
chr4_+_132567420 1.994 NM_146155
Ahdc1
AT hook, DNA binding motif, containing 1
chr2_+_150612469 1.993 NM_153781
Pygb
brain glycogen phosphorylase
chr3_+_17954500 1.986 Bhlhe22
basic helix-loop-helix family, member e22
chr9_-_108092712 1.978 NM_007567
Bsn
bassoon
chr7_-_116925058 1.969 NM_020610
Nrip3
nuclear receptor interacting protein 3
chr2_+_119568028 1.968 NM_146125
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr15_+_99223377 1.965 NM_001171034
NM_001171036
NM_026669
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr6_-_113481340 1.963 Tmem111
transmembrane protein 111
chr4_-_128798939 1.962 NM_001130419
Hpca
hippocalcin
chr2_-_60047891 1.942 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_154719834 1.940 NM_001039079
Prkcz
protein kinase C, zeta
chr9_-_89517823 1.934 NM_153509
AF529169
cDNA sequence AF529169
chr2_-_92886300 1.934 NM_001177536
Prdm11
PR domain containing 11
chr16_-_20241392 1.934 NM_198599
Map6d1
MAP6 domain containing 1
chr5_+_52755183 1.921 Sod3
superoxide dismutase 3, extracellular
chr11_+_101107691 1.919 Vps25
vacuolar protein sorting 25 (yeast)
chr12_-_71448300 1.907 Trim9
tripartite motif-containing 9
chr18_+_35000283 1.876 NM_144865
Reep2
receptor accessory protein 2
chr11_-_121249511 1.867 NM_139147
Rab40b
Rab40b, member RAS oncogene family
chr7_-_13619936 1.864 NM_026885
Chmp2a
chromatin modifying protein 2A
chr5_-_124171015 1.864 NM_027494
Zcchc8
zinc finger, CCHC domain containing 8
chr2_-_60047804 1.855 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr9_-_53822931 1.852 Elmod1
ELMO domain containing 1
chr6_-_124867872 1.847 Ptms
parathymosin
chr4_-_119165183 1.837 NM_177572
Rimkla
ribosomal modification protein rimK-like family member A
chr7_-_53435334 1.835 NM_011510
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr7_+_17529961 1.835 NM_001099636
Pnmal2
PNMA-like 2
chr2_+_128891655 1.835 NM_027192
Ttl
tubulin tyrosine ligase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.77 7.16e-08 GO:0007399 nervous system development
4.70 2.09e-07 GO:0019226 transmission of nerve impulse
4.70 2.09e-07 GO:0035637 multicellular organismal signaling
5.75 3.50e-06 GO:0050804 regulation of synaptic transmission
2.92 7.07e-06 GO:0022008 neurogenesis
1.98 9.65e-06 GO:0048731 system development
5.33 1.16e-05 GO:0051969 regulation of transmission of nerve impulse
2.03 1.70e-05 GO:0048523 negative regulation of cellular process
2.15 1.87e-05 GO:0065008 regulation of biological quality
1.89 2.33e-05 GO:0006810 transport
3.37 2.87e-05 GO:0030182 neuron differentiation
1.87 3.89e-05 GO:0048856 anatomical structure development
1.77 4.03e-05 GO:0051179 localization
4.90 4.23e-05 GO:0031644 regulation of neurological system process
2.03 4.65e-05 GO:0048869 cellular developmental process
1.86 4.77e-05 GO:0051234 establishment of localization
2.86 4.93e-05 GO:0048699 generation of neurons
1.93 5.26e-05 GO:0048519 negative regulation of biological process
1.76 6.19e-05 GO:0032502 developmental process
2.03 8.75e-05 GO:0030154 cell differentiation
1.78 1.21e-04 GO:0007275 multicellular organismal development
1.78 2.14e-04 GO:0016043 cellular component organization
4.28 3.35e-04 GO:0007268 synaptic transmission
3.22 6.96e-04 GO:0050801 ion homeostasis
5.05 1.02e-03 GO:0042391 regulation of membrane potential
1.71 1.28e-03 GO:0071840 cellular component organization or biogenesis
2.53 1.36e-03 GO:0048468 cell development
2.84 1.56e-03 GO:0048878 chemical homeostasis
2.77 1.57e-03 GO:0007154 cell communication
3.23 2.02e-03 GO:0006873 cellular ion homeostasis
2.09 2.13e-03 GO:0023051 regulation of signaling
3.33 2.16e-03 GO:0043549 regulation of kinase activity
3.15 3.08e-03 GO:0055082 cellular chemical homeostasis
1.31 3.16e-03 GO:0065007 biological regulation
3.36 3.30e-03 GO:0045859 regulation of protein kinase activity
3.23 3.50e-03 GO:0007267 cell-cell signaling
3.34 3.59e-03 GO:0007610 behavior
3.19 4.25e-03 GO:0051338 regulation of transferase activity
2.88 4.90e-03 GO:0019725 cellular homeostasis
4.12 5.28e-03 GO:0051129 negative regulation of cellular component organization
1.81 6.37e-03 GO:0071842 cellular component organization at cellular level
2.06 6.93e-03 GO:0009653 anatomical structure morphogenesis
9.75 8.39e-03 GO:0007269 neurotransmitter secretion
2.35 9.24e-03 GO:0042592 homeostatic process
3.14 9.25e-03 GO:0044057 regulation of system process
3.03 9.28e-03 GO:0007417 central nervous system development
4.17 9.82e-03 GO:0044087 regulation of cellular component biogenesis
2.19 1.13e-02 GO:0010646 regulation of cell communication
3.04 1.49e-02 GO:0048666 neuron development
2.35 1.73e-02 GO:0051128 regulation of cellular component organization
6.06 2.26e-02 GO:0006836 neurotransmitter transport
1.50 2.30e-02 GO:0019222 regulation of metabolic process
1.94 2.38e-02 GO:0051239 regulation of multicellular organismal process
2.93 2.53e-02 GO:0060341 regulation of cellular localization
1.72 3.06e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.53 3.10e-02 GO:0031323 regulation of cellular metabolic process
3.51 3.60e-02 GO:0033674 positive regulation of kinase activity
2.85 3.66e-02 GO:0007010 cytoskeleton organization
13.32 3.79e-02 GO:0016079 synaptic vesicle exocytosis
2.54 3.86e-02 GO:0016192 vesicle-mediated transport
1.53 4.21e-02 GO:0080090 regulation of primary metabolic process
6.45 4.22e-02 GO:0001505 regulation of neurotransmitter levels

Gene overrepresentation in compartment category:

enrichment p-value GO term description
4.63 4.23e-12 GO:0045202 synapse
4.97 1.74e-09 GO:0044456 synapse part
1.87 2.21e-09 GO:0071944 cell periphery
1.84 1.84e-08 GO:0005886 plasma membrane
3.42 9.71e-08 GO:0030054 cell junction
7.21 1.64e-07 GO:0019717 synaptosome
2.20 5.20e-07 GO:0044459 plasma membrane part
1.19 1.09e-06 GO:0005623 cell
1.19 1.09e-06 GO:0044464 cell part
1.41 1.32e-06 GO:0005737 cytoplasm
5.91 3.04e-06 GO:0030135 coated vesicle
6.30 3.64e-06 GO:0030136 clathrin-coated vesicle
3.20 8.18e-06 GO:0043005 neuron projection
2.92 8.39e-06 GO:0031410 cytoplasmic vesicle
7.43 1.60e-05 GO:0008021 synaptic vesicle
2.75 3.52e-05 GO:0031982 vesicle
3.18 5.05e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
2.32 5.27e-05 GO:0000267 cell fraction
1.26 6.97e-05 GO:0005622 intracellular
49.02 7.35e-05 GO:0008091 spectrin
1.27 1.01e-04 GO:0044424 intracellular part
2.52 1.12e-04 GO:0005624 membrane fraction
2.48 1.16e-04 GO:0005626 insoluble fraction
3.01 1.42e-04 GO:0031988 membrane-bounded vesicle
2.27 3.15e-04 GO:0042995 cell projection
2.03 7.93e-04 GO:0005856 cytoskeleton
3.66 1.03e-03 GO:0030425 dendrite
12.68 1.33e-03 GO:0030672 synaptic vesicle membrane
1.27 3.10e-03 GO:0043229 intracellular organelle
1.41 3.12e-03 GO:0044444 cytoplasmic part
1.26 3.79e-03 GO:0043226 organelle
3.24 5.05e-03 GO:0043025 neuronal cell body
1.91 5.34e-03 GO:0005829 cytosol
7.95 5.64e-03 GO:0030665 clathrin coated vesicle membrane
3.08 9.31e-03 GO:0044297 cell body
1.28 1.01e-02 GO:0016020 membrane
5.91 1.34e-02 GO:0014069 postsynaptic density
4.19 1.48e-02 GO:0045211 postsynaptic membrane
3.18 1.84e-02 GO:0044431 Golgi apparatus part
3.30 2.14e-02 GO:0030424 axon
9.89 2.87e-02 GO:0044304 main axon
6.13 3.06e-02 GO:0030662 coated vesicle membrane
26.26 3.08e-02 GO:0043218 compact myelin
2.07 3.13e-02 GO:0044430 cytoskeletal part
2.52 4.81e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

enrichment p-value GO term description
1.81 7.86e-15 GO:0005515 protein binding
1.35 4.10e-09 GO:0005488 binding
5.48 1.44e-03 GO:0005516 calmodulin binding
12.26 1.18e-02 GO:0015296 anion:cation symporter activity
8.76 1.49e-02 GO:0000149 SNARE binding
16.34 2.14e-02 GO:0004697 protein kinase C activity
2.54 2.49e-02 GO:0008092 cytoskeletal protein binding