Motif ID: ZNF143.p2

Z-value: 4.124

Transcription factors associated with ZNF143.p2:

NameEntrezDescription
Zfp143 20841 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Zfp143chr7_+_1172051940.799.3e-09Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr12_-_114067537 20.265 NM_028023
Cdca4
cell division cycle associated 4
chr8_+_73988823 20.051 NM_053162
Mrpl34
mitochondrial ribosomal protein L34
chr9_-_37240759 18.375 NM_001164767
Robo3
roundabout homolog 3 (Drosophila)
chr11_+_69809250 15.309 NM_030064
Phf23
PHD finger protein 23
chr6_+_4697305 14.737 NM_001040611
NM_130877
Peg10

paternally expressed 10

chr2_-_153067043 14.293 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr1_-_16647097 13.133 Tceb1
transcription elongation factor B (SIII), polypeptide 1
chr5_-_34000546 12.933 Tmem129
transmembrane protein 129
chr8_+_124474432 12.736 NM_001110100
NM_016812
Banp

BTG3 associated nuclear protein

chr9_-_107775031 12.376 NM_011251
NM_029169
Rbm6

RNA binding motif protein 6

chr7_-_30954705 11.211 NM_011980
Zfp146
zinc finger protein 146
chr10_-_128002991 11.185 Pa2g4
proliferation-associated 2G4
chr8_+_108384479 11.153 NM_026532
Nutf2
nuclear transport factor 2
chr11_+_117710532 9.853 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr18_+_34784589 9.774 NM_009004
NM_001166406
Kif20a

kinesin family member 20A

chr7_+_28516407 9.677 NM_009560
NM_029531
Zfp60

zinc finger protein 60

chr15_-_81560309 9.091 NM_001146174
NM_011241
Rangap1

RAN GTPase activating protein 1

chr7_+_25292105 8.595 NM_146183
Zfp428
zinc finger protein 428
chr2_-_165213726 8.420 NM_178411
Zfp334
zinc finger protein 334
chr2_-_84567398 8.404 Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr10_+_79642100 8.328 NM_007909
Efna2
ephrin A2
chr6_-_92133945 8.283 NM_025578
Mrps25
mitochondrial ribosomal protein S25
chr7_+_107520844 8.264 C2cd3
C2 calcium-dependent domain containing 3
chr1_+_178744942 8.055 NM_029756
Sdccag8
serologically defined colon cancer antigen 8
chr2_-_84567424 7.621 NM_133840
Clp1
CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
chr12_+_8778152 7.500 Sdc1
syndecan 1
chr14_-_55136145 7.436 NM_013768
Prmt5
protein arginine N-methyltransferase 5
chr7_+_140050907 7.364 NM_198017
Fam175b
family with sequence similarity 175, member B
chr8_-_59966523 7.308 NM_021788
Sap30
sin3 associated polypeptide
chr2_-_26359261 7.123 NM_008714
Notch1
Notch gene homolog 1 (Drosophila)
chr2_+_71050002 7.086 NM_001198877
NM_001198878
NM_010064
Dync1i2


dynein cytoplasmic 1 intermediate chain 2


chr4_+_124334876 7.067 NM_011141
Pou3f1
POU domain, class 3, transcription factor 1
chr15_-_81560302 7.051 Rangap1
RAN GTPase activating protein 1
chr17_-_23810808 7.051 Thoc6
THO complex 6 homolog (Drosophila)
chr11_-_77707282 7.044 NM_008952
Pipox
pipecolic acid oxidase
chr9_-_34983552 7.040 NM_027030
Dcps
decapping enzyme, scavenger
chr5_-_124170947 6.857 Zcchc8
zinc finger, CCHC domain containing 8
chr4_-_62069611 6.825 NM_139291
Cdc26
cell division cycle 26
chr10_-_99949933 6.621 NM_001033332
NM_001110013
Tmtc3

transmembrane and tetratricopeptide repeat containing 3

chr17_+_26012421 6.534 NM_026686
0610011F06Rik
RIKEN cDNA 0610011F06 gene
chr3_+_109143558 6.444 NM_020505
Vav3
vav 3 oncogene
chr19_-_14672540 6.276 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr1_-_33871349 6.229 Zfp451
zinc finger protein 451
chr6_-_35083605 6.195 Cnot4
CCR4-NOT transcription complex, subunit 4
chr11_-_116029436 6.186 NM_172571
Fbf1
Fas (TNFRSF6) binding factor 1
chr19_+_6334978 6.083 NM_001168488
NM_001168489
NM_001168490
NM_008583
Men1



multiple endocrine neoplasia 1



chr1_-_181733742 6.080 Ahctf1
AT hook containing transcription factor 1
chr2_+_172847371 6.073 NM_019547
Rbm38
RNA binding motif protein 38
chr2_-_69551514 5.950 Fastkd1
FAST kinase domains 1
chrX_-_137077133 5.923 Tsc22d3
TSC22 domain family, member 3
chr5_-_23929347 5.838 NM_007668
Cdk5
cyclin-dependent kinase 5
chr2_+_71049762 5.809 NM_001198872
NM_001198873
NM_001198874
NM_001198875
NM_001198876
Dync1i2




dynein cytoplasmic 1 intermediate chain 2




chr12_+_107248496 5.731 Vrk1
vaccinia related kinase 1
chr4_+_116381175 5.638 Ccdc163
coiled-coil domain containing 163
chr9_+_48863685 5.637 NM_012039
Zw10
ZW10 homolog (Drosophila), centromere/kinetochore protein
chr6_-_34126949 5.603 NM_021435
Slc35b4
solute carrier family 35, member B4
chr11_+_76220643 5.502 NM_019818
NM_023355
Timm22

translocase of inner mitochondrial membrane 22 homolog (yeast)

chr7_+_13864164 5.484 NM_010715
Lig1
ligase I, DNA, ATP-dependent
chrX_-_136533089 5.470 NM_001172147
NM_001172148
NM_153586
Rbm41


RNA binding motif protein 41


chr15_-_9070066 5.437 NM_013787
NM_145468
Skp2

S-phase kinase-associated protein 2 (p45)

chr14_+_76245136 5.395 Tpt1
tumor protein, translationally-controlled 1
chr5_+_140895245 5.373 NM_133916
Eif3b
eukaryotic translation initiation factor 3, subunit B
chr7_+_25292201 5.347 Zfp428
zinc finger protein 428
chr7_-_99889932 5.337 4632427E13Rik
RIKEN cDNA 4632427E13 gene
chr12_+_76919276 5.288 NM_001005510
Syne2
synaptic nuclear envelope 2
chr6_-_90732001 5.274 E130314K07Rik
RIKEN cDNA E130314K07 gene
chr5_+_147042806 5.215 Cdk8
cyclin-dependent kinase 8
chr17_+_26389911 5.215 Luc7l
Luc7 homolog (S. cerevisiae)-like
chr4_-_49533914 5.198 NM_178603
Mrpl50
mitochondrial ribosomal protein L50
chr13_-_58316923 5.117 Ubqln1
ubiquilin 1
chr15_-_77801154 5.064 NM_018749
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr6_-_72739189 5.054 Tcf7l1
transcription factor 7-like 1 (T-cell specific, HMG box)
chr2_+_165818136 5.045 NM_008679
Ncoa3
nuclear receptor coactivator 3
chr7_+_138009310 5.044 NM_133942
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr11_+_80623859 5.024 NM_029537
Tmem98
transmembrane protein 98
chr17_-_3557712 4.952 NM_146074
Tfb1m
transcription factor B1, mitochondrial
chr2_+_118423946 4.941 NM_009773
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr3_-_122322556 4.929 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr17_+_13109289 4.926 NM_013686
Tcp1
t-complex protein 1
chr19_-_14672472 4.874 NM_011600
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr7_-_105805050 4.856 NM_172280
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr7_+_123236814 4.841 NM_019772
1110004F10Rik
RIKEN cDNA 1110004F10 gene
chr2_+_90519527 4.824 Nup160
nucleoporin 160
chr15_-_81560283 4.823 Rangap1
RAN GTPase activating protein 1
chr4_+_48292705 4.822 Invs
inversin
chr8_+_108734906 4.788 NM_145404
Prmt7
protein arginine N-methyltransferase 7
chr9_+_65974417 4.740 NM_026635
Fam96a
family with sequence similarity 96, member A
chr15_-_44259378 4.739 Nudcd1
NudC domain containing 1
chr9_-_103104394 4.716 NM_009275
Srprb
signal recognition particle receptor, B subunit
chr5_+_108494692 4.695 NM_013827
Mtf2
metal response element binding transcription factor 2
chr2_-_139996251 4.684 NM_001081090
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr7_+_30088984 4.679 NM_013874
Dpf1
D4, zinc and double PHD fingers family 1
chr10_-_121063321 4.642 NM_001081056
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr11_+_70833066 4.585 NM_025993
Mis12
MIS12 homolog (yeast)
chr1_-_153275461 4.584 1200016B10Rik
RIKEN cDNA 1200016B10 gene
chr6_-_4697009 4.572 NM_001130188
NM_001130189
NM_001130190
NM_001130191
NM_011360
Sgce




sarcoglycan, epsilon




chr7_-_52241669 4.564 NM_019830
Prmt1
protein arginine N-methyltransferase 1
chr9_-_20954341 4.558 NM_016742
Cdc37
cell division cycle 37 homolog (S. cerevisiae)
chr16_-_55934909 4.538 NM_001159364
NM_001159365
NM_001159366
NM_028815
Cep97



centrosomal protein 97



chr10_-_117147722 4.517 Mdm2
transformed mouse 3T3 cell double minute 2
chrX_-_137491205 4.496 NM_001164177
NM_016883
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr18_-_24179208 4.483 NM_021559
Zfp191
zinc finger protein 191
chr18_-_85120875 4.473 NM_025969
1700034H14Rik
RIKEN cDNA 1700034H14 gene
chr10_-_128002934 4.460 Pa2g4
proliferation-associated 2G4
chr10_-_128003058 4.457 Pa2g4
proliferation-associated 2G4
chr15_+_76181718 4.449 NM_001164607
NM_001164608
NM_026859
Maf1


MAF1 homolog (S. cerevisiae)


chr16_-_96349292 4.429 NM_008251
Hmgn1
high mobility group nucleosomal binding domain 1
chr1_+_94831282 4.429 Capn10
calpain 10
chr11_+_60513191 4.422 NM_001159404
NM_001159405
NM_008502
Llgl1


lethal giant larvae homolog 1 (Drosophila)


chr14_-_19103447 4.418 NM_025586
Rpl15
ribosomal protein L15
chr13_-_115248924 4.404 NM_008046
Fst
follistatin
chr8_+_3493117 4.400 NM_080461
Zfp358
zinc finger protein 358
chr5_-_145952388 4.394 Atp5j2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr4_-_59796621 4.393 NM_001013577
1110054O05Rik
RIKEN cDNA 1110054O05 gene
chr4_-_116380924 4.389 NM_025962
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr2_+_164595415 4.346 NM_026785
Ube2c
ubiquitin-conjugating enzyme E2C
chr7_-_107007401 4.338 Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr18_-_46685557 4.310 NM_173423
Fem1c
fem-1 homolog c (C.elegans)
chr15_-_75900118 4.307 NM_134089
Scrib
scribbled homolog (Drosophila)
chr8_+_124474484 4.300 Banp
BTG3 associated nuclear protein
chr14_+_65568881 4.276 NM_153414
Ints9
integrator complex subunit 9
chr1_+_153275671 4.266 NM_026876
1190005F20Rik
RIKEN cDNA 1190005F20 gene
chr2_+_165818161 4.261 Ncoa3
nuclear receptor coactivator 3
chr10_+_111409750 4.251 NM_178610
Krr1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr7_-_134655863 4.233 1700008J07Rik
RIKEN cDNA 1700008J07 gene
chr7_-_13864014 4.218 NM_177312
6330408A02Rik
RIKEN cDNA 6330408A02 gene
chr14_+_55713789 4.212 Thtpa
thiamine triphosphatase
chr10_+_74980789 4.205 Snrpd3
small nuclear ribonucleoprotein D3
chr13_-_35998160 4.192 NM_145938
Rpp40
ribonuclease P 40 subunit (human)
chr19_+_10680032 4.170 NM_015735
Ddb1
damage specific DNA binding protein 1
chr7_-_31337285 4.163 NM_183321
BC053749
cDNA sequence BC053749
chr9_-_72833159 4.142 NM_001198789
Gm5918
predicted gene 5918
chr11_-_60692261 4.120 Tmem11
transmembrane protein 11
chr17_-_85189859 4.063 Lrpprc
leucine-rich PPR-motif containing
chr4_-_120597563 4.045 NM_001160043
NM_028457
Dem1

defects in morphology 1 homolog (S. cerevisiae)

chr11_-_101140242 4.043 NM_026618
Ccdc56
coiled-coil domain containing 56
chr16_-_87496048 4.030 NM_009840
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr14_+_58042878 3.998 NM_009376
Ift88
intraflagellar transport 88 homolog (Chlamydomonas)
chr19_+_37281988 3.971 NM_001164336
NM_001164337
NM_027314
March5


membrane-associated ring finger (C3HC4) 5


chr18_-_25327116 3.956 5730494M16Rik
RIKEN cDNA 5730494M16 gene
chr4_-_123427465 3.924 NM_023423
Akirin1
akirin 1
chr13_+_38296760 3.916 NM_026382
Snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr5_+_23900197 3.910 Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr14_+_76245115 3.896 Tpt1
tumor protein, translationally-controlled 1
chr3_+_68808879 3.894 NM_133786
Smc4
structural maintenance of chromosomes 4
chrX_+_20235512 3.885 NM_009457
Uba1
ubiquitin-like modifier activating enzyme 1
chr4_+_62069853 3.866 Prpf4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr4_-_126738303 3.853 NM_026670
Zmym1
zinc finger, MYM domain containing 1
chr7_-_107007359 3.847 NM_025668
Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr4_-_151370212 3.845 NM_172705
Phf13
PHD finger protein 13
chr17_+_26389892 3.830 Luc7l
Luc7 homolog (S. cerevisiae)-like
chr11_+_70265445 3.818 Med11
mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
chr7_-_126138646 3.814 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr11_-_107050573 3.809 NM_001161329
NM_133702
Nol11

nucleolar protein 11

chr2_+_181599126 3.798 Polr3k
polymerase (RNA) III (DNA directed) polypeptide K
chr13_-_97312427 3.789 NM_012048
Polk
polymerase (DNA directed), kappa
chr8_-_73421276 3.762 NM_001111116
Gm15427
Rpl18a
predicted pseudogene 15427
ribosomal protein L18A
chr1_+_192752462 3.756 Angel2
angel homolog 2 (Drosophila)
chr7_+_30093030 3.755 Dpf1
D4, zinc and double PHD fingers family 1
chr6_+_35127603 3.732 NM_027513
Nup205
nucleoporin 205
chr7_+_30880094 3.705 NM_011981
Zfp260
zinc finger protein 260
chr9_+_22280158 3.691 NM_178415
NM_181316
Bbs9

Bardet-Biedl syndrome 9 (human)

chrX_-_136533042 3.691 Rbm41
RNA binding motif protein 41
chr19_+_47806216 3.683 NM_026377
6330577E15Rik
RIKEN cDNA 6330577E15 gene
chr2_-_68310324 3.681 Stk39
serine/threonine kinase 39, STE20/SPS1 homolog (yeast)
chr12_+_8778201 3.675 NM_011519
Sdc1
syndecan 1
chr8_-_110112260 3.674 Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr2_+_153067186 3.673 NM_080463
Pofut1
protein O-fucosyltransferase 1
chr14_-_57190668 3.673 NM_001014996
Cenpj
centromere protein J
chr7_+_50927384 3.671 NM_145582
Ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr7_+_30553570 3.650 NM_023750
Zfp84
zinc finger protein 84
chr11_-_106860750 3.635 Kpna2
karyopherin (importin) alpha 2
chr19_-_46072931 3.615 NM_198296
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr6_+_67216948 3.611 NM_001113564
NM_001113565
NM_001113566
NM_025814
Serbp1



serpine1 mRNA binding protein 1



chr8_-_93837120 3.609 NM_173431
Rpgrip1l
Rpgrip1-like
chr7_-_27981077 3.606 NM_015782
Snrpa
small nuclear ribonucleoprotein polypeptide A
chr2_+_154959216 3.602 NM_008395
Itch
itchy, E3 ubiquitin protein ligase
chr2_-_69044179 3.575 NM_025565
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr16_-_96349334 3.569 Hmgn1
high mobility group nucleosomal binding domain 1
chr4_+_100449274 3.568 NM_198037
Cachd1
cache domain containing 1
chr2_-_152240515 3.556 Zcchc3
zinc finger, CCHC domain containing 3
chr11_-_23795215 3.541 NM_172555
Papolg
poly(A) polymerase gamma
chr2_-_125684720 3.540 NM_009939
Cops2
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chr1_-_93295259 3.537 Ilkap
integrin-linked kinase-associated serine/threonine phosphatase 2C
chr7_+_6124083 3.535 NM_001146024
NM_028316
Zfp444

zinc finger protein 444

chr16_+_43890014 3.514 NM_027801
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr1_+_74708306 3.510 NM_001014974
Ttll4
tubulin tyrosine ligase-like family, member 4
chr7_+_108966826 3.503 NM_008887
Phox2a
paired-like homeobox 2a
chr11_+_69393851 3.499 NM_001127233
NM_011640
Trp53

transformation related protein 53

chr9_+_108199200 3.498 NM_001013814
Amt
aminomethyltransferase
chr7_+_129302950 3.493 NM_011121
Plk1
polo-like kinase 1 (Drosophila)
chr10_+_43298969 3.490 NM_009846
Cd24a
CD24a antigen
chr5_-_151468105 3.487 NM_201369
N4bp2l2
NEDD4 binding protein 2-like 2
chr11_+_48613820 3.454 NM_008143
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr13_+_49436905 3.445 NM_001039179
NM_001039180
NM_029791
Bicd2


bicaudal D homolog 2 (Drosophila)


chr2_-_75819804 3.437 NM_030188
Ttc30a1
tetratricopeptide repeat domain 30A1
chr7_+_138703898 3.402 NM_009774
Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chrX_+_120217131 3.396 NM_028426
3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr18_+_50287848 3.391 NM_008292
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
chr7_+_129302998 3.388 Plk1
polo-like kinase 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.77 1.49e-24 GO:0044260 cellular macromolecule metabolic process
1.64 4.16e-20 GO:0043170 macromolecule metabolic process
1.99 3.12e-19 GO:0090304 nucleic acid metabolic process
1.94 2.17e-16 GO:0010467 gene expression
1.79 2.11e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 1.22e-14 GO:0044237 cellular metabolic process
1.93 2.83e-14 GO:0016070 RNA metabolic process
1.44 7.01e-13 GO:0044238 primary metabolic process
3.16 7.90e-13 GO:0006396 RNA processing
1.67 1.11e-12 GO:0034641 cellular nitrogen compound metabolic process
3.57 2.12e-12 GO:0000278 mitotic cell cycle
1.64 5.26e-12 GO:0006807 nitrogen compound metabolic process
3.93 8.33e-11 GO:0008380 RNA splicing
2.53 1.27e-10 GO:0007049 cell cycle
1.79 1.47e-10 GO:0034645 cellular macromolecule biosynthetic process
1.78 2.96e-10 GO:0009059 macromolecule biosynthetic process
3.74 4.81e-10 GO:0006397 mRNA processing
1.34 2.01e-09 GO:0008152 metabolic process
2.71 5.27e-09 GO:0022402 cell cycle process
3.22 2.14e-08 GO:0016071 mRNA metabolic process
1.73 4.29e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.95 5.71e-08 GO:0006996 organelle organization
6.38 1.08e-07 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.47 1.22e-07 GO:0006511 ubiquitin-dependent protein catabolic process
3.69 1.38e-07 GO:0048285 organelle fission
3.37 1.50e-07 GO:0051603 proteolysis involved in cellular protein catabolic process
3.39 2.31e-07 GO:0019941 modification-dependent protein catabolic process
3.31 2.51e-07 GO:0044257 cellular protein catabolic process
1.72 2.54e-07 GO:0071842 cellular component organization at cellular level
3.36 2.85e-07 GO:0043632 modification-dependent macromolecule catabolic process
3.64 3.76e-07 GO:0000087 M phase of mitotic cell cycle
3.16 5.75e-07 GO:0030163 protein catabolic process
2.80 7.50e-07 GO:0044265 cellular macromolecule catabolic process
6.47 8.44e-07 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.61 9.04e-07 GO:0000280 nuclear division
3.61 9.04e-07 GO:0007067 mitosis
1.55 1.37e-06 GO:0044249 cellular biosynthetic process
1.54 1.43e-06 GO:0009058 biosynthetic process
6.20 1.77e-06 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
6.11 2.24e-06 GO:0051352 negative regulation of ligase activity
6.11 2.24e-06 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.11 2.24e-06 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.50 2.40e-06 GO:0060255 regulation of macromolecule metabolic process
1.55 2.92e-06 GO:0071840 cellular component organization or biogenesis
5.33 2.94e-06 GO:0051438 regulation of ubiquitin-protein ligase activity
5.21 4.33e-06 GO:0051340 regulation of ligase activity
2.55 6.54e-06 GO:0009057 macromolecule catabolic process
1.57 6.85e-06 GO:0010468 regulation of gene expression
5.22 1.11e-05 GO:0031397 negative regulation of protein ubiquitination
2.88 1.28e-05 GO:0051301 cell division
5.42 1.58e-05 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.84 1.77e-05 GO:0000279 M phase
1.53 1.84e-05 GO:0016043 cellular component organization
5.29 2.34e-05 GO:0051351 positive regulation of ligase activity
1.61 2.49e-05 GO:0044267 cellular protein metabolic process
3.96 2.51e-05 GO:0031396 regulation of protein ubiquitination
1.70 2.91e-05 GO:0006351 transcription, DNA-dependent
2.58 3.13e-05 GO:0022403 cell cycle phase
1.70 3.21e-05 GO:0032774 RNA biosynthetic process
1.58 4.11e-05 GO:0051252 regulation of RNA metabolic process
3.90 7.04e-05 GO:0010498 proteasomal protein catabolic process
3.90 7.04e-05 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.44 9.67e-05 GO:0080090 regulation of primary metabolic process
4.33 1.05e-04 GO:0031398 positive regulation of protein ubiquitination
1.53 1.39e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.40 1.52e-04 GO:0019222 regulation of metabolic process
1.49 3.29e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 3.75e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.41 4.19e-04 GO:0031323 regulation of cellular metabolic process
2.32 4.23e-04 GO:0006259 DNA metabolic process
5.18 5.77e-04 GO:0000375 RNA splicing, via transesterification reactions
1.50 6.14e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.53 6.16e-04 GO:0006355 regulation of transcription, DNA-dependent
3.38 9.01e-04 GO:0031400 negative regulation of protein modification process
2.43 9.58e-04 GO:0006974 response to DNA damage stimulus
2.70 1.35e-03 GO:0006281 DNA repair
6.10 1.83e-03 GO:0006261 DNA-dependent DNA replication
4.88 3.06e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
4.88 3.06e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
4.88 3.06e-03 GO:0022618 ribonucleoprotein complex assembly
3.04 3.30e-03 GO:0033365 protein localization to organelle
4.00 3.33e-03 GO:0071156 regulation of cell cycle arrest
3.02 3.61e-03 GO:0071843 cellular component biogenesis at cellular level
4.21 3.64e-03 GO:0000075 cell cycle checkpoint
1.80 3.88e-03 GO:0008104 protein localization
4.07 5.53e-03 GO:0034504 protein localization to nucleus
4.61 6.00e-03 GO:0071826 ribonucleoprotein complex subunit organization
2.83 6.91e-03 GO:0010564 regulation of cell cycle process
2.21 7.05e-03 GO:0034613 cellular protein localization
1.78 7.17e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.43 7.37e-03 GO:0019538 protein metabolic process
2.68 8.20e-03 GO:0032269 negative regulation of cellular protein metabolic process
2.19 8.27e-03 GO:0070727 cellular macromolecule localization
1.42 8.75e-03 GO:0031326 regulation of cellular biosynthetic process
2.73 8.87e-03 GO:0007017 microtubule-based process
1.42 1.10e-02 GO:0009889 regulation of biosynthetic process
4.31 1.30e-02 GO:0050657 nucleic acid transport
4.31 1.30e-02 GO:0050658 RNA transport
4.31 1.30e-02 GO:0051236 establishment of RNA localization
3.15 1.51e-02 GO:0006260 DNA replication
2.43 1.64e-02 GO:0034621 cellular macromolecular complex subunit organization
2.91 1.78e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.56 1.79e-02 GO:0051248 negative regulation of protein metabolic process
3.21 1.95e-02 GO:0051169 nuclear transport
4.15 2.00e-02 GO:0006403 RNA localization
4.44 2.10e-02 GO:0051028 mRNA transport
1.66 2.38e-02 GO:0033036 macromolecule localization
2.61 2.89e-02 GO:0016567 protein ubiquitination
2.46 3.71e-02 GO:0034622 cellular macromolecular complex assembly
1.12 4.05e-02 GO:0009987 cellular process
2.49 4.19e-02 GO:0032446 protein modification by small protein conjugation
2.82 4.59e-02 GO:0007346 regulation of mitotic cell cycle
2.33 4.94e-02 GO:0070647 protein modification by small protein conjugation or removal

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.91 1.09e-38 GO:0005634 nucleus
1.45 1.73e-38 GO:0044424 intracellular part
1.44 3.50e-38 GO:0005622 intracellular
1.51 4.33e-35 GO:0043229 intracellular organelle
1.51 1.09e-34 GO:0043226 organelle
1.54 4.81e-32 GO:0043231 intracellular membrane-bounded organelle
1.54 8.60e-32 GO:0043227 membrane-bounded organelle
1.94 8.17e-24 GO:0032991 macromolecular complex
2.29 2.29e-20 GO:0044428 nuclear part
1.74 7.64e-20 GO:0044446 intracellular organelle part
1.71 1.30e-18 GO:0044422 organelle part
1.89 2.35e-14 GO:0043228 non-membrane-bounded organelle
1.89 2.35e-14 GO:0043232 intracellular non-membrane-bounded organelle
2.08 1.49e-13 GO:0070013 intracellular organelle lumen
2.08 1.73e-13 GO:0043233 organelle lumen
3.26 3.31e-13 GO:0030529 ribonucleoprotein complex
1.77 6.67e-13 GO:0043234 protein complex
2.03 8.46e-13 GO:0031974 membrane-enclosed lumen
2.10 5.96e-12 GO:0031981 nuclear lumen
1.29 4.24e-08 GO:0005737 cytoplasm
2.09 1.32e-07 GO:0005654 nucleoplasm
1.12 2.34e-06 GO:0005623 cell
1.12 2.34e-06 GO:0044464 cell part
4.19 3.61e-06 GO:0005681 spliceosomal complex
2.35 4.30e-06 GO:0015630 microtubule cytoskeleton
2.41 4.13e-05 GO:0005694 chromosome
2.43 1.00e-04 GO:0044427 chromosomal part
5.62 1.08e-04 GO:0000502 proteasome complex
1.29 2.94e-04 GO:0044444 cytoplasmic part
3.59 4.13e-04 GO:0000775 chromosome, centromeric region
1.65 5.36e-04 GO:0005856 cytoskeleton
1.63 8.81e-04 GO:0005829 cytosol
2.61 1.71e-03 GO:0005874 microtubule
3.71 1.81e-03 GO:0000151 ubiquitin ligase complex
5.80 1.81e-03 GO:0005643 nuclear pore
3.02 3.29e-03 GO:0005840 ribosome
4.15 3.94e-03 GO:0071013 catalytic step 2 spliceosome
2.81 3.96e-03 GO:0005813 centrosome
2.66 6.26e-03 GO:0005815 microtubule organizing center
2.23 6.37e-03 GO:0005730 nucleolus
3.86 8.77e-03 GO:0000776 kinetochore
3.39 1.07e-02 GO:0005819 spindle
4.19 1.64e-02 GO:0031461 cullin-RING ubiquitin ligase complex
1.69 1.80e-02 GO:0044430 cytoskeletal part
4.32 2.70e-02 GO:0046930 pore complex
1.50 3.57e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment p-value GO term description
1.65 1.68e-08 GO:0003676 nucleic acid binding
1.18 2.46e-05 GO:0005488 binding
2.12 2.78e-05 GO:0003723 RNA binding
1.54 2.72e-03 GO:0003677 DNA binding
25.50 2.04e-02 GO:0044020 histone methyltransferase activity (H4-R3 specific)
4.88 2.53e-02 GO:0008170 N-methyltransferase activity
14.57 2.54e-02 GO:0008469 histone-arginine N-methyltransferase activity
3.90 3.62e-02 GO:0008565 protein transporter activity
1.41 3.75e-02 GO:0000166 nucleotide binding