Motif ID: ZNF423.p2

Z-value: 1.165

Transcription factors associated with ZNF423.p2:

NameEntrezDescription
Zfp423 94187 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Zfp423chr8_-_904833920.411.2e-02Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr2_-_29108440 6.242 6530402F18Rik
RIKEN cDNA 6530402F18 gene
chr12_-_14158843 5.437 NM_029007
Fam84a
family with sequence similarity 84, member A
chr6_+_110595574 4.758 Grm7
glutamate receptor, metabotropic 7
chr4_+_42930076 4.691 NM_172690
N28178
expressed sequence N28178
chr11_+_120582777 4.089 NM_133223
Rac3
RAS-related C3 botulinum substrate 3
chr9_-_99776467 3.245 NM_011440
Sox14
SRY-box containing gene 14
chr13_+_13876570 3.172 Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr1_-_12980994 3.084 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr9_-_37360141 3.017 NM_022029
Nrgn
neurogranin
chr7_+_152082435 2.982 NM_008003
Fgf15
fibroblast growth factor 15
chr5_-_136410393 2.883 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr10_-_108447996 2.852 Syt1
synaptotagmin I
chr3_+_96404978 2.849 NM_001163170
Lix1l
Lix1-like
chr9_+_120401723 2.795 NM_026892
Eif1b
eukaryotic translation initiation factor 1B
chr19_-_5098498 2.733 Cnih2
cornichon homolog 2 (Drosophila)
chr5_+_81449776 2.690 Lphn3
latrophilin 3
chr19_+_7049425 2.606 NM_008889
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_13495931 2.517 NM_011701
Vim
vimentin
chr13_-_100286446 2.414 Mtap1b
microtubule-associated protein 1B
chr10_-_61573705 2.299 NM_027251
2010107G23Rik
RIKEN cDNA 2010107G23 gene
chr10_-_108448003 2.216 Syt1
synaptotagmin I
chr11_-_107656007 2.167 Cacng4
calcium channel, voltage-dependent, gamma subunit 4
chr5_-_99681835 1.996 NM_145839
NM_181318
Rasgef1b

RasGEF domain family, member 1B

chr19_-_5098486 1.948 Cnih2
cornichon homolog 2 (Drosophila)
chrX_+_55283804 1.945 NM_009575
Zic3
zinc finger protein of the cerebellum 3
chr18_+_40416615 1.941 2900055J20Rik
RIKEN cDNA 2900055J20 gene
chr2_+_154617083 1.930 Raly
a
hnRNP-associated with lethal yellow
nonagouti
chr15_-_75397601 1.860 NM_011837
Ly6h
lymphocyte antigen 6 complex, locus H
chr8_+_125935441 1.859 NM_023279
Tubb3
tubulin, beta 3
chr1_+_136456781 1.844 Kdm5b
lysine (K)-specific demethylase 5B
chr10_-_80945445 1.839 NM_176954
Celf5
CUGBP, Elav-like family member 5
chr14_-_56519012 1.838 NM_001082975
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr5_-_136410488 1.837 NM_018871
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr10_-_126497197 1.809 NM_001033262
March9
membrane-associated ring finger (C3HC4) 9
chr4_+_129190877 1.809 Marcksl1
MARCKS-like 1
chrX_-_34529439 1.775 NM_001177323
Sept6
septin 6
chr7_+_152024499 1.773 NM_008007
Fgf3
fibroblast growth factor 3
chr18_+_59334993 1.734 NM_001081328
Chsy3
chondroitin sulfate synthase 3
chr7_+_129210954 1.694 Ubfd1
ubiquitin family domain containing 1
chr5_-_21850490 1.618 NM_011261
Reln
reelin
chr10_-_80945379 1.602 Celf5
CUGBP, Elav-like family member 5
chr1_+_53353919 1.578 NM_145517
Ormdl1
ORM1-like 1 (S. cerevisiae)
chr10_+_86241749 1.577 NM_175331
Nt5dc3
5'-nucleotidase domain containing 3
chr2_-_29108499 1.494 6530402F18Rik
RIKEN cDNA 6530402F18 gene
chr1_+_169528492 1.391 NM_009107
Rxrg
retinoid X receptor gamma
chr8_-_67171805 1.357 NM_013494
Cpe
carboxypeptidase E
chr17_+_56125891 1.355 NM_183178
Fsd1
fibronectin type 3 and SPRY domain-containing protein
chr13_+_54605152 1.340 NM_176987
4732471D19Rik
RIKEN cDNA 4732471D19 gene
chr12_+_112997057 1.339 NM_001025360
NM_001081959
NM_008450
Klc1


kinesin light chain 1


chr17_-_25570721 1.305 NM_001163691
NM_021415
Cacna1h

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr7_+_51565563 1.301 NM_001034115
Shank1
SH3/ankyrin domain gene 1
chr8_+_37157910 1.294 D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr1_+_136456754 1.285 NM_152895
Kdm5b
lysine (K)-specific demethylase 5B
chr3_-_107434441 1.278 NM_153563
Fam40a
family with sequence similarity 40, member A
chr1_-_164408008 1.277 Dnm3
dynamin 3
chr8_-_97362140 1.230 NM_134141
Ciapin1
cytokine induced apoptosis inhibitor 1
chr9_+_26541302 1.228 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_-_164408123 1.207 Dnm3
dynamin 3
chr2_+_163820857 1.205 Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr19_+_10116104 1.184 Fads3
fatty acid desaturase 3
chr13_+_55701256 1.183 NM_146045
B4galt7
xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr10_-_108447894 1.174 Syt1
synaptotagmin I
chr5_-_139605617 1.174 NM_008923
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr12_-_25780932 1.168 NM_010496
Id2
inhibitor of DNA binding 2
chr2_+_106533281 1.161 Mpped2
metallophosphoesterase domain containing 2
chr16_-_35769389 1.159 NM_153550
Dirc2
disrupted in renal carcinoma 2 (human)
chr5_+_88994019 1.149 Rufy3
RUN and FYVE domain containing 3
chr4_+_104040160 1.146 NM_010014
NM_177259
Dab1

disabled homolog 1 (Drosophila)

chr7_-_118923483 1.141 NM_173739
Galntl4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr11_-_69373555 1.141 Efnb3
ephrin B3
chr12_+_104187054 1.138 Unc79
unc-79 homolog (C. elegans)
chr2_+_174155592 1.123 NM_001077510
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr5_-_138182307 1.121 6430598A04Rik
RIKEN cDNA 6430598A04 gene
chr19_+_47253626 1.104 Neurl1a
neuralized homolog 1A (Drosophila)
chr19_-_5098381 1.082 NM_009920
Cnih2
cornichon homolog 2 (Drosophila)
chr5_-_23929349 1.077 Cdk5
cyclin-dependent kinase 5
chr11_-_60988419 1.066 Usp22
ubiquitin specific peptidase 22
chr17_-_15963372 1.063 NM_178615
Rgmb
RGM domain family, member B
chr15_+_101004502 1.060 NM_007395
Acvr1b
activin A receptor, type 1B
chr2_-_24618566 1.035 NM_001042528
NM_007579
Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr7_+_30093030 1.009 Dpf1
D4, zinc and double PHD fingers family 1
chr2_+_179177132 1.006 NM_009867
Cdh4
cadherin 4
chr2_-_73749317 0.995 NM_175015
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr13_-_100286521 0.981 NM_008634
Mtap1b
microtubule-associated protein 1B
chr6_-_58857000 0.978 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chr2_+_174155515 0.976 NM_201616
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr15_-_97077552 0.969 NM_001164563
NM_001164602
NM_178114
Amigo2


adhesion molecule with Ig like domain 2


chr9_-_78226334 0.966 NM_026480
Ooep
oocyte expressed protein homolog (dog)
chr3_-_127599117 0.965 NM_027482
5730508B09Rik
RIKEN cDNA 5730508B09 gene
chr10_-_80945428 0.960 Celf5
CUGBP, Elav-like family member 5
chr1_+_59969845 0.949 NM_001037725
Fam117b
family with sequence similarity 117, member B
chr4_+_129190872 0.927 Marcksl1
MARCKS-like 1
chr17_-_46169322 0.923 NM_001025250
NM_001025257
NM_009505
Vegfa


vascular endothelial growth factor A


chr11_-_69373707 0.918 NM_007911
Efnb3
ephrin B3
chr17_-_47748155 0.917 Bysl
bystin-like
chr6_-_124364880 0.913 NM_008995
NM_175933
Pex5

peroxisomal biogenesis factor 5

chr19_+_45122281 0.912 Sfxn3
sideroflexin 3
chr5_-_100158034 0.908 A930011G23Rik
RIKEN cDNA A930011G23 gene
chr6_-_128312829 0.907 5930416I19Rik
RIKEN cDNA 5930416I19 gene
chr3_+_134491969 0.898 NM_021382
Tacr3
tachykinin receptor 3
chr8_+_85689250 0.895 NM_001111304
NM_027758
Tbc1d9

TBC1 domain family, member 9

chr7_-_52124950 0.863 Ptov1
prostate tumor over expressed gene 1
chr8_-_73223897 0.841 Gm11175
predicted gene 11175
chr6_+_110595586 0.835 NM_177328
Grm7
glutamate receptor, metabotropic 7
chr15_-_100382354 0.834 NM_033476
Tcfcp2
transcription factor CP2
chr11_-_115397455 0.833 NM_133354
Sumo2
SMT3 suppressor of mif two 3 homolog 2 (yeast)
chr1_+_136456741 0.832 Kdm5b
lysine (K)-specific demethylase 5B
chr1_+_17135421 0.827 NM_010267
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr13_-_93300744 0.823 NM_173392
Zfyve16
zinc finger, FYVE domain containing 16
chrX_+_71574403 0.812 NM_008883
Plxna3
plexin A3
chr11_-_60988490 0.796 NM_001004143
Usp22
ubiquitin specific peptidase 22
chr14_-_32249046 0.796 NM_011894
Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr3_+_94217197 0.794 NM_028307
Tdrkh
tudor and KH domain containing protein
chr11_+_78640103 0.788 1810012P15Rik
RIKEN cDNA 1810012P15 gene
chr11_+_100948587 0.784 NM_001159384
NM_001159385
NM_011550
Mlx


MAX-like protein X


chr11_+_78640059 0.769 NM_001076681
1810012P15Rik
RIKEN cDNA 1810012P15 gene
chr10_-_80317936 0.759 NM_025349
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_11033219 0.758 NM_016694
Park2
Parkinson disease (autosomal recessive, juvenile) 2, parkin
chr7_+_129210847 0.751 Ubfd1
ubiquitin family domain containing 1
chr9_+_45238375 0.747 NM_001081270
Dscaml1
Down syndrome cell adhesion molecule-like 1
chr7_-_29551532 0.736 NM_010908
Nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chrX_+_97963061 0.727 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr16_+_52031733 0.719 Cblb
Casitas B-lineage lymphoma b
chr11_-_5965626 0.713 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr15_-_44619541 0.713 NM_001032727
NM_176998
Sybu

syntabulin (syntaxin-interacting)

chr2_+_3035692 0.712 Fam171a1
family with sequence similarity 171, member A1
chr2_-_90420529 0.709 Ptprj
protein tyrosine phosphatase, receptor type, J
chr8_+_123192124 0.699 NM_009941
Cox4i1
Cox4nb
cytochrome c oxidase subunit IV isoform 1
COX4 neighbor
chr15_+_74346853 0.699 Bai1
brain-specific angiogenesis inhibitor 1
chr10_-_127057998 0.699 Lrp1
low density lipoprotein receptor-related protein 1
chr5_-_23929347 0.698 NM_007668
Cdk5
cyclin-dependent kinase 5
chr9_+_57385317 0.697 NM_001166364
NM_175273
2310046O06Rik

RIKEN cDNA 2310046O06 gene

chr13_+_100877966 0.688 NM_011353
Serf1
small EDRK-rich factor 1
chr5_-_23536439 0.685 Fam126a
family with sequence similarity 126, member A
chr13_-_55672471 0.685 NM_145382
Fam193b
family with sequence similarity 193, member B
chr1_+_169528838 0.683 Rxrg
retinoid X receptor gamma
chr7_-_112781902 0.682 NM_018880
Trim3
tripartite motif-containing 3
chr5_-_131783731 0.675 Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr3_-_10440061 0.675 NM_001127191
NM_029068
Snx16

sorting nexin 16

chr7_+_129210948 0.666 Ubfd1
ubiquitin family domain containing 1
chr1_+_5073161 0.655 NM_133826
Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr4_+_40917975 0.650 NM_023739
Nfx1
nuclear transcription factor, X-box binding 1
chr7_+_87414540 0.649 NM_178070
Vps33b
vacuolar protein sorting 33B (yeast)
chr11_-_33103458 0.645 NM_019916
Tlx3
T-cell leukemia, homeobox 3
chr10_-_121484248 0.644 NM_001081037
Srgap1
SLIT-ROBO Rho GTPase activating protein 1
chr17_+_43938789 0.639 NM_207649
Rcan2
regulator of calcineurin 2
chr9_-_42752453 0.625 NM_175481
Grik4
glutamate receptor, ionotropic, kainate 4
chr14_-_94289847 0.617 Pcdh9
protocadherin 9
chr3_+_83570228 0.611 NM_009144
Sfrp2
secreted frizzled-related protein 2
chr7_-_150085870 0.610 NM_009377
Th
tyrosine hydroxylase
chr11_+_71564204 0.606 NM_177618
Wscd1
WSC domain containing 1
chr15_-_83002624 0.605 NM_029787
Cyb5r3
cytochrome b5 reductase 3
chr2_+_130100145 0.602 NM_024193
Nop56
NOP56 ribonucleoprotein homolog (yeast)
chr16_-_22439642 0.595 NM_023794
Etv5
ets variant gene 5
chr14_-_40286236 0.594 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr4_-_134409254 0.587 NM_025382
Tmem57
transmembrane protein 57
chr5_-_131783942 0.581 Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr15_-_80094668 0.578 NM_175109
Rps19bp1
ribosomal protein S19 binding protein 1
chr8_-_89409079 0.573 NM_030563
N4bp1
NEDD4 binding protein 1
chr11_-_108205240 0.568 Prkca
protein kinase C, alpha
chr11_-_29925939 0.562 NM_146016
Eml6
echinoderm microtubule associated protein like 6
chr19_+_29326204 0.556 NM_001048177
NM_008413
Jak2

Janus kinase 2

chr9_+_56978554 0.553 NM_028636
Man2c1
mannosidase, alpha, class 2C, member 1
chr8_-_105308910 0.550 NM_009866
Cdh11
cadherin 11
chr1_+_121422719 0.546 NM_146103
Tmem185b
transmembrane protein 185B
chr1_-_164408133 0.545 NM_001038619
NM_172646
Dnm3

dynamin 3

chr2_-_39046224 0.544 NM_178778
Scai
suppressor of cancer cell invasion
chr15_-_89260070 0.542


chr4_-_15076093 0.538 NM_178617
Necab1
N-terminal EF-hand calcium binding protein 1
chr2_-_30214724 0.534 NM_139302
Sh3glb2
SH3-domain GRB2-like endophilin B2
chr8_+_125935470 0.531 Tubb3
tubulin, beta 3
chr17_-_46693110 0.528 NM_020493
Srf
serum response factor
chr12_+_79327737 0.527 Gphn
gephyrin
chr16_+_52031704 0.526 Cblb
Casitas B-lineage lymphoma b
chr15_+_74394184 0.517 Bai1
brain-specific angiogenesis inhibitor 1
chr1_+_129765349 0.515 NM_178690
Rab3gap1
RAB3 GTPase activating protein subunit 1
chr2_+_32143868 0.515 Golga2
golgi autoantigen, golgin subfamily a, 2
chr15_-_43002356 0.513 NM_172815
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr5_-_23953594 0.509 NM_022418
Tmub1
transmembrane and ubiquitin-like domain containing 1
chr4_+_151460980 0.506 Plekhg5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_-_14425271 0.504 NM_025418
Vta1
Vps20-associated 1 homolog (S. cerevisiae)
chr17_+_87362450 0.500 NM_145491
Rhoq
ras homolog gene family, member Q
chr18_+_52928026 0.499 Gm5078
Sncaip
predicted gene 5078
synuclein, alpha interacting protein (synphilin)
chr2_-_94246839 0.498 NM_183106
Ttc17
tetratricopeptide repeat domain 17
chr9_-_120401664 0.495 D830035M03Rik
RIKEN cDNA D830035M03 gene
chr19_-_6141100 0.493 NM_019722
Arl2
ADP-ribosylation factor-like 2
chr5_-_23929280 0.492 Cdk5
cyclin-dependent kinase 5
chr6_+_54631644 0.491 NM_026629
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr11_-_43649708 0.489 NM_007416
Adra1b
adrenergic receptor, alpha 1b
chr15_+_74346835 0.486 Bai1
brain-specific angiogenesis inhibitor 1
chr2_+_158436493 0.486 NM_009508
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr6_-_37249957 0.480 NM_001081206
Dgki
diacylglycerol kinase, iota
chr8_-_49075884 0.478 NM_133791
Wwc2
WW, C2 and coiled-coil domain containing 2
chr4_-_98787525 0.474 NM_026082
Dock7
dedicator of cytokinesis 7
chr1_-_75188292 0.474 Atg9a
autophagy-related 9A (yeast)
chr14_-_52935887 0.471 Sall2
sal-like 2 (Drosophila)
chr6_-_85452851 0.469 NM_001001160
Fbxo41
F-box protein 41
chr5_-_139801315 0.466 NM_172723
Adap1
ArfGAP with dual PH domains 1
chr13_+_13876667 0.463 NM_010317
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr1_-_63160764 0.460 NM_001081436
NM_001114609
Ino80d

INO80 complex subunit D


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.81 1.15e-03 GO:0048731 system development
5.90 3.16e-03 GO:0030030 cell projection organization
6.77 3.19e-03 GO:0007610 behavior
3.75 3.62e-03 GO:0007399 nervous system development
4.56 4.92e-03 GO:0048699 generation of neurons
2.52 7.30e-03 GO:0048856 anatomical structure development
6.93 9.21e-03 GO:0031175 neuron projection development
25.08 9.29e-03 GO:0016358 dendrite development
4.27 9.41e-03 GO:0022008 neurogenesis
4.14 1.27e-02 GO:0048468 cell development
13.40 1.72e-02 GO:0030534 adult behavior
7.22 2.46e-02 GO:0045664 regulation of neuron differentiation
37.61 3.26e-02 GO:0021795 cerebral cortex cell migration
2.29 3.52e-02 GO:0007275 multicellular organismal development
11.41 3.72e-02 GO:0006184 GTP catabolic process
35.98 3.74e-02 GO:0017158 regulation of calcium ion-dependent exocytosis
4.89 4.15e-02 GO:0030182 neuron differentiation
11.13 4.17e-02 GO:0007411 axon guidance
5.47 4.88e-02 GO:0048666 neuron development

Gene overrepresentation in compartment category:

enrichment p-value GO term description
7.47 1.01e-07 GO:0043005 neuron projection
4.47 1.41e-05 GO:0042995 cell projection
9.56 3.98e-05 GO:0030424 axon
6.07 1.65e-03 GO:0044463 cell projection part
6.86 2.11e-03 GO:0043025 neuronal cell body
6.54 2.98e-03 GO:0044297 cell body
5.22 5.40e-03 GO:0045202 synapse
6.79 7.73e-03 GO:0030425 dendrite
5.81 2.03e-02 GO:0044456 synapse part
13.63 2.20e-02 GO:0030426 growth cone
13.14 2.53e-02 GO:0030427 site of polarized growth
2.21 2.89e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

enrichment p-value GO term description
35.98 7.62e-03 GO:0005245 voltage-gated calcium channel activity
9.14 2.15e-02 GO:0003924 GTPase activity