Motif ID: bHLH_family.p2

Z-value: 2.129

Transcription factors associated with bHLH_family.p2:

NameEntrezDescription
Arntl 11865 aryl hydrocarbon receptor nuclear translocator-like
Arntl2 272322 aryl hydrocarbon receptor nuclear translocator-like 2
Clock 12753 circadian locomotor output cycles kaput
Hes6 55927 hairy and enhancer of split 6 (Drosophila)
Hey1 15213 hairy/enhancer-of-split related with YRPW motif 1
Hey2 15214 hairy/enhancer-of-split related with YRPW motif 2
Heyl 56198 hairy/enhancer-of-split related with YRPW motif-like
Id1 15901 inhibitor of DNA binding 1
Mitf 17342 microphthalmia-associated transcription factor
Mlxipl 58805 MLX interacting protein-like
Mnt 17428 max binding protein
Mxd3 17121 Max dimerization protein 3
Mxd4 17122 Max dimerization protein 4
Mxi1 17859 Max interacting protein 1
Npas2 18143 neuronal PAS domain protein 2
Olig1 50914 oligodendrocyte transcription factor 1
Olig2 50913 oligodendrocyte transcription factor 2
Tcfe3 209446 transcription factor E3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Hey1chr3_-_86669300.751.8e-07Click!
Mxd3chr13_-_554310270.742.3e-07Click!
Mxi1chr19_+_534039020.554.5e-04Click!
Olig1chr16_+_912700090.502.1e-03Click!
Mitfchr6_+_977570120.465.0e-03Click!
Tcfe3chrX_+_73399420.447.8e-03Click!
Mlxiplchr5_+_1355827540.391.9e-02Click!
Mntchr11_+_74644479-0.363.2e-02Click!
Clockchr5_-_767337700.325.4e-02Click!
Hes6chr1_-_93309713-0.325.5e-02Click!
Heylchr4_+_1229110600.326.1e-02Click!
Hey2chr10_-_305624340.299.1e-02Click!
Id1chr2_+_1525619830.222.1e-01Click!
Mxd4chr5_-_345302210.163.7e-01Click!
Arntlchr7_+_1203510120.153.9e-01Click!
Olig2chr16_+_91225794-0.115.2e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr8_+_13159279 14.415 Lamp1
lysosomal-associated membrane protein 1
chr15_-_78236262 13.678 NM_009437
Tst
thiosulfate sulfurtransferase, mitochondrial
chr1_-_75215798 13.455 NM_009447
Tuba4a
tubulin, alpha 4A
chr17_-_45732442 11.652 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr3_+_104442568 11.628 NM_009196
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr8_-_3624988 9.067 NM_001129804
Pcp2
Purkinje cell protein 2 (L7)
chr7_+_3303657 8.574 NM_011102
Prkcc
protein kinase C, gamma
chr5_+_137506122 8.305 NM_001039385
Vgf
VGF nerve growth factor inducible
chr10_+_122115755 8.160 NM_001110218
NM_176919
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr4_+_15808409 7.621 NM_009788
Calb1
calbindin 1
chr8_-_3625251 6.734 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr11_+_53333270 6.268 NM_033144
Sept8
septin 8
chr8_-_89996089 6.083 Cbln1
cerebellin 1 precursor protein
chr7_-_152125661 6.048 Ccnd1
cyclin D1
chr5_-_77524256 5.826 NM_001159900
NM_001159901
Hopx

HOP homeobox

chr19_+_4510471 5.573 NM_001162946
Pcx
pyruvate carboxylase
chr11_+_117670970 5.566 NM_009304
Syngr2
synaptogyrin 2
chr17_-_27075896 5.558 Cuta
cutA divalent cation tolerance homolog (E. coli)
chr8_+_13159112 5.365 NM_010684
Lamp1
lysosomal-associated membrane protein 1
chr19_+_10092665 5.309 NM_144538
Rab3il1
RAB3A interacting protein (rabin3)-like 1
chr11_-_54846882 5.160 NM_001110211
NM_013472
Anxa6

annexin A6

chr10_+_122116066 5.013 Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr6_-_125444722 4.937 NM_007657
Cd9
CD9 antigen
chr11_-_60624592 4.880 Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr15_+_38908403 4.825 NM_026778
Cthrc1
collagen triple helix repeat containing 1
chr10_+_79317316 4.668 NM_001077363
NM_008956
Ptbp1

polypyrimidine tract binding protein 1

chr2_+_31742800 4.667 NM_011836
Lamc3
laminin gamma 3
chr17_-_27076365 4.655 NM_026307
NM_026948
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr10_+_56097078 4.594 NM_010288
Gja1
gap junction protein, alpha 1
chr17_-_25707599 4.572 NM_011447
Sox8
SRY-box containing gene 8
chr7_+_108496574 4.558 NM_001040111
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_+_116288075 4.486 NM_027920
March8
membrane-associated ring finger (C3HC4) 8
chr1_-_136131399 4.478 Adora1
adenosine A1 receptor
chr11_-_69734369 4.234 NM_001166592
NM_001166594
Eif5a

eukaryotic translation initiation factor 5A

chr14_-_19071459 4.213 NM_011584
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr17_+_45700882 4.198 Slc35b2
solute carrier family 35, member B2
chr10_+_128346900 4.129 NM_007653
Cd63
CD63 antigen
chr16_-_22657245 3.975 Dgkg
diacylglycerol kinase, gamma
chr13_-_94269673 3.914 Jmy
junction-mediating and regulatory protein
chr4_+_129985957 3.834 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chr7_-_91234908 3.746 NM_030728
9930013L23Rik
RIKEN cDNA 9930013L23 gene
chr6_-_23789259 3.687 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr17_-_53828547 3.650 Sgol1
shugoshin-like 1 (S. pombe)
chr10_+_41239248 3.617 NM_016898
Cd164
CD164 antigen
chr3_+_87710282 3.597 Hdgf
hepatoma-derived growth factor
chr16_-_95219189 3.536 NM_001025584
NM_001025585
NM_010606
Kcnj6


potassium inwardly-rectifying channel, subfamily J, member 6


chr11_-_93816916 3.518 NM_001077529
Nme2
non-metastatic cells 2, protein (NM23B) expressed in
chr4_-_25727109 3.503 NM_010243
Fut9
fucosyltransferase 9
chr7_+_117265568 3.492 NM_009516
Wee1
WEE 1 homolog 1 (S. pombe)
chr19_-_10278231 3.455 NM_007999
Fen1
flap structure specific endonuclease 1
chr1_-_17087915 3.447 Jph1
junctophilin 1
chr5_-_46030523 3.391 NM_021416
Fam184b
family with sequence similarity 184, member B
chr13_+_38436987 3.386 Bmp6
bone morphogenetic protein 6
chr7_+_129432810 3.351 Prkcb
protein kinase C, beta
chr1_-_155179844 3.342 NM_010683
Lamc1
laminin, gamma 1
chr7_-_105509797 3.340 NM_001024619
NM_001168540
NM_001168541
NM_001168539
Tsku



tsukushin



chr3_-_95686120 3.278 NM_001033302
Gm129
predicted gene 129
chr5_+_45884612 3.275 NM_024434
Lap3
leucine aminopeptidase 3
chr15_+_73578771 3.265 Ptp4a3
protein tyrosine phosphatase 4a3
chr6_+_108163089 3.231 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr17_-_48061354 3.210 Foxp4
forkhead box P4
chr1_-_72920776 3.193 Igfbp5
insulin-like growth factor binding protein 5
chr11_+_69814046 3.169 NM_007888
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr11_+_61298923 3.101 NM_029568
Mfap4
microfibrillar-associated protein 4
chr10_+_122116022 3.040


chr7_-_29096957 3.009 NM_025616
Timm50
translocase of inner mitochondrial membrane 50 homolog (yeast)
chr17_+_46633703 3.000 NM_207161
BC048355
cDNA sequence BC048355
chr5_-_44492908 2.989 NM_001163577
NM_008935
Prom1

prominin 1

chr15_+_81641869 2.969 Tef
thyrotroph embryonic factor
chr10_+_125403274 2.965 NM_177152
Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr7_-_104566013 2.961 NM_009381
Thrsp
thyroid hormone responsive SPOT14 homolog (Rattus)
chr16_+_20672770 2.951 NM_001005331
NM_145941
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr17_+_53618611 2.942 Rab5a
RAB5A, member RAS oncogene family
chr18_-_15562126 2.941 NM_009700
Aqp4
aquaporin 4
chr11_+_16652205 2.912 NM_007912
NM_207655
Egfr

epidermal growth factor receptor

chr9_-_22193577 2.902 Anln
anillin, actin binding protein
chr13_-_114408704 2.894 NM_130796
Snx18
sorting nexin 18
chr10_-_120913138 2.840 NM_138956
Rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr1_+_93076578 2.838 Ramp1
receptor (calcitonin) activity modifying protein 1
chr7_+_120909680 2.837 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr6_-_131338282 2.835 Csda
cold shock domain protein A
chr15_+_54402914 2.834 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr5_-_138613028 2.832 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_+_46647881 2.826 Sfxn2
sideroflexin 2
chr8_-_87297283 2.805 Nfix
nuclear factor I/X
chrX_+_70748418 2.774 NM_177236
Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
chr8_-_72498125 2.731 Gatad2a
GATA zinc finger domain containing 2A
chr2_-_147011990 2.713 NM_001077632
NM_010919
Nkx2-2

NK2 transcription factor related, locus 2 (Drosophila)

chr19_-_3686441 2.710 NM_008513
Lrp5
low density lipoprotein receptor-related protein 5
chr14_+_35124004 2.707 Glud1
glutamate dehydrogenase 1
chr8_-_72498210 2.697 NM_001113346
Gatad2a
GATA zinc finger domain containing 2A
chr15_+_34012415 2.680 NM_026002
Mtdh
metadherin
chr7_-_152125823 2.677 NM_007631
Ccnd1
cyclin D1
chr17_-_53828596 2.665 NM_028232
Sgol1
shugoshin-like 1 (S. pombe)
chr2_+_92755251 2.629 NM_030725
Syt13
synaptotagmin XIII
chr4_+_8617613 2.624 Chd7
chromodomain helicase DNA binding protein 7
chr3_-_50247306 2.621 NM_011990
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chrX_+_149574498 2.605 NM_001004154
Rragb
Ras-related GTP binding B
chr9_+_107489981 2.584 NM_025903
Ifrd2
interferon-related developmental regulator 2
chr17_-_10512217 2.555 NM_001159516
NM_001159517
NM_021881
Qk


quaking


chr11_-_95936914 2.543 NM_001161419
NM_007506
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr3_+_90417072 2.540 S100a6
S100 calcium binding protein A6 (calcyclin)
chr12_-_103057259 2.540 NM_011812
Fbln5
fibulin 5
chr2_-_144096164 2.524 Snx5
sorting nexin 5
chr12_-_77811119 2.520 Spnb1
spectrin beta 1
chr16_-_95218980 2.485 Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr15_-_93166789 2.478 Yaf2
YY1 associated factor 2
chr5_+_98683202 2.474 NM_010203
Fgf5
fibroblast growth factor 5
chr16_+_45158943 2.460 Atg3
autophagy-related 3 (yeast)
chr2_+_166631011 2.459 NM_001085495
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_-_98636538 2.458 NM_145434
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr7_+_135667095 2.429 NM_013863
Bag3
BCL2-associated athanogene 3
chr7_+_35904310 2.408 NM_007678
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_-_154395469 2.386 NM_007891
E2f1
E2F transcription factor 1
chr7_+_120909625 2.373 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr3_+_135488617 2.368 NM_001135149
NM_001135150
Slc39a8

solute carrier family 39 (metal ion transporter), member 8

chr16_-_22657283 2.358 NM_138650
Dgkg
diacylglycerol kinase, gamma
chr8_-_89996474 2.286 NM_019626
Cbln1
cerebellin 1 precursor protein
chr11_-_101646571 2.284 NM_008815
Etv4
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr4_-_136512727 2.268 NM_007939
Epha8
Eph receptor A8
chr16_-_57606866 2.255 NM_025599
2610528E23Rik
RIKEN cDNA 2610528E23 gene
chr19_+_23215704 2.250 NM_010638
Klf9
Kruppel-like factor 9
chr12_+_16660521 2.243 Ntsr2
neurotensin receptor 2
chrX_+_33868347 2.242 NM_028894
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr18_-_60908267 2.233 Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr18_+_56867378 2.229 NM_010721
Lmnb1
lamin B1
chr4_-_25726753 2.218 Fut9
fucosyltransferase 9
chr2_+_156301543 2.200 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr5_-_124053691 2.186 Clip1
CAP-GLY domain containing linker protein 1
chr11_-_79317471 2.176 Omg
oligodendrocyte myelin glycoprotein
chr15_+_66409094 2.173 NM_001081409
Phf20l1
PHD finger protein 20-like 1
chr1_+_9535477 2.161 NM_021511
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr2_+_71819264 2.159 NM_019688
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_+_8617550 2.156 Chd7
chromodomain helicase DNA binding protein 7
chr8_+_77617514 2.151 NM_010442
Hmox1
heme oxygenase (decycling) 1
chr2_+_164659268 2.148 Ctsa
cathepsin A
chr15_-_38230397 2.128 NM_013692
Klf10
Kruppel-like factor 10
chr17_+_35137995 2.108 Vars
valyl-tRNA synthetase
chr12_-_103056971 2.098 Fbln5
fibulin 5
chr13_-_94269616 2.082 NM_021310
Jmy
junction-mediating and regulatory protein
chr14_-_62301012 2.069 Dleu2
deleted in lymphocytic leukemia, 2
chr4_+_97444563 2.068 Nfia
nuclear factor I/A
chr8_-_113917651 2.052 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr7_+_26444141 2.049 NM_138586
Exosc5
exosome component 5
chr7_-_97278443 2.040 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr2_-_79296732 2.037 NM_010894
Neurod1
neurogenic differentiation 1
chr6_+_108610606 2.035 NM_011498
Bhlhe40
basic helix-loop-helix family, member e40
chr15_-_78994753 2.035 NM_011437
Sox10
SRY-box containing gene 10
chr5_+_102194207 2.021 Cds1
CDP-diacylglycerol synthase 1
chr7_+_134913327 2.017 NM_198424
Orai3
ORAI calcium release-activated calcium modulator 3
chr11_-_70796432 1.999 C1qbp
complement component 1, q subcomponent binding protein
chr7_+_129432585 1.981 NM_008855
Prkcb
protein kinase C, beta
chr16_+_18877336 1.971 Hira
histone cell cycle regulation defective homolog A (S. cerevisiae)
chr10_-_126778941 1.970 Gli1
GLI-Kruppel family member GLI1
chr19_+_10057131 1.951 NM_010239
Fth1
ferritin heavy chain 1
chr4_+_84851440 1.942 Sh3gl2
SH3-domain GRB2-like 2
chr5_-_124482223 1.941 NM_177876
Vps37b
vacuolar protein sorting 37B (yeast)
chr14_+_9046655 1.941 NM_027782
Kctd6
potassium channel tetramerisation domain containing 6
chr10_-_5913894 1.910 NM_024261
1700052N19Rik
RIKEN cDNA 1700052N19 gene
chr8_-_124431581 1.897 NM_011404
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr10_-_24919916 1.891 Akap7
A kinase (PRKA) anchor protein 7
chr4_+_129725083 1.887 NM_028266
Col16a1
collagen, type XVI, alpha 1
chr11_+_84693721 1.887 NM_025414
Myo19
myosin XIX
chr10_-_127962914 1.885 NM_011843
Esyt1
extended synaptotagmin-like protein 1
chr4_+_15192892 1.883 NM_181401
Tmem64
transmembrane protein 64
chr5_-_77380189 1.880 Ppat
phosphoribosyl pyrophosphate amidotransferase
chr16_+_20672847 1.873 Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr4_+_155366962 1.872 Sdf4
stromal cell derived factor 4
chr14_+_122874598 1.870 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr10_+_127759640 1.870 Cnpy2
canopy 2 homolog (zebrafish)
chr7_+_16683891 1.859 NM_025898
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chrX_+_149574541 1.854 Rragb
Ras-related GTP binding B
chr10_+_126500607 1.839 NM_009870
Cdk4
cyclin-dependent kinase 4
chr10_+_125403223 1.839 Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_-_137352181 1.832 NM_007431
Alpl
alkaline phosphatase, liver/bone/kidney
chr2_+_31428244 1.828 NM_001033389
Fubp3
far upstream element (FUSE) binding protein 3
chr1_-_53841997 1.826 NM_133810
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr6_+_29644178 1.824 NM_146173
Tspan33
tetraspanin 33
chr4_+_40216581 1.823 2010003O02Rik
RIKEN cDNA 2010003O02 gene
chr6_+_128313041 1.816 Foxm1
forkhead box M1
chr3_-_101408495 1.788 NM_144900
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr12_-_11443284 1.783 NM_012038
Vsnl1
visinin-like 1
chr15_-_79518160 1.771 NM_028792
Josd1
Josephin domain containing 1
chr4_-_134260127 1.769 NM_207237
Man1c1
mannosidase, alpha, class 1C, member 1
chr11_-_109334465 1.764 NM_134038
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_+_77992224 1.761 NM_026708
Tlcd1
TLC domain containing 1
chr2_+_112079943 1.761 NM_207206
Lpcat4
lysophosphatidylcholine acyltransferase 4
chr2_-_84510822 1.757 NM_001033166
NM_001037279
2700094K13Rik

RIKEN cDNA 2700094K13 gene

chr19_-_42203380 1.756 NM_027106
Avpi1
arginine vasopressin-induced 1
chr6_-_125263750 1.755 NM_010736
Ltbr
lymphotoxin B receptor
chr9_+_83441886 1.745 NM_172507
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr10_-_94786634 1.745 NM_009950
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr16_+_44139908 1.743 NM_028108
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_+_74462965 1.716 NM_001081158
1300001I01Rik
RIKEN cDNA 1300001I01 gene
chr6_+_128312987 1.710 NM_008021
Foxm1
forkhead box M1
chr1_+_55462764 1.710 NM_001114663
Plcl1
phospholipase C-like 1
chr11_+_119804400 1.705 NM_001037754
NM_001037755
NM_130862
Baiap2


brain-specific angiogenesis inhibitor 1-associated protein 2


chr7_-_31758390 1.699 NM_001164184
NM_001164185
NM_017405
Lsr


lipolysis stimulated lipoprotein receptor


chr13_-_112599181 1.692 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr2_+_25227840 1.691 NM_001081085
2010317E24Rik
RIKEN cDNA 2010317E24 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
1.93 1.18e-09 GO:0051179 localization
1.29 6.09e-09 GO:0009987 cellular process
1.94 1.65e-07 GO:0006810 transport
1.92 1.79e-07 GO:0051234 establishment of localization
1.74 2.09e-05 GO:0044249 cellular biosynthetic process
1.44 2.24e-05 GO:0044237 cellular metabolic process
1.72 2.31e-05 GO:0009058 biosynthetic process
1.84 2.44e-05 GO:0048522 positive regulation of cellular process
1.75 8.26e-05 GO:0048518 positive regulation of biological process
2.48 9.52e-05 GO:0042127 regulation of cell proliferation
1.63 1.28e-04 GO:0034641 cellular nitrogen compound metabolic process
1.62 1.38e-04 GO:0006807 nitrogen compound metabolic process
2.11 1.42e-04 GO:0023051 regulation of signaling
2.08 1.62e-04 GO:0051239 regulation of multicellular organismal process
1.80 1.90e-04 GO:0048731 system development
1.70 1.98e-04 GO:0007275 multicellular organismal development
2.18 5.05e-04 GO:0009966 regulation of signal transduction
1.81 7.39e-04 GO:0048523 negative regulation of cellular process
1.54 7.61e-04 GO:0019222 regulation of metabolic process
1.96 9.48e-04 GO:0048583 regulation of response to stimulus
1.38 9.85e-04 GO:0044238 primary metabolic process
1.69 1.15e-03 GO:0048856 anatomical structure development
1.61 1.38e-03 GO:0032502 developmental process
1.64 1.79e-03 GO:0071840 cellular component organization or biogenesis
1.65 1.87e-03 GO:0016043 cellular component organization
3.33 2.65e-03 GO:0035295 tube development
1.72 2.91e-03 GO:0048519 negative regulation of biological process
2.08 3.22e-03 GO:0033036 macromolecule localization
1.32 3.45e-03 GO:0008152 metabolic process
2.07 5.01e-03 GO:0007399 nervous system development
2.14 5.98e-03 GO:0050793 regulation of developmental process
2.42 6.66e-03 GO:0055085 transmembrane transport
1.53 6.72e-03 GO:0031323 regulation of cellular metabolic process
5.09 6.90e-03 GO:0010038 response to metal ion
1.82 6.93e-03 GO:0065008 regulation of biological quality
1.57 7.15e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86 7.36e-03 GO:0044281 small molecule metabolic process
2.53 7.85e-03 GO:0048878 chemical homeostasis
1.62 8.06e-03 GO:0009889 regulation of biosynthetic process
2.14 8.27e-03 GO:0008104 protein localization
2.16 8.66e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.62 9.13e-03 GO:0031326 regulation of cellular biosynthetic process
2.12 1.03e-02 GO:0051641 cellular localization
2.27 1.33e-02 GO:0006811 ion transport
1.51 1.51e-02 GO:0080090 regulation of primary metabolic process
1.79 1.53e-02 GO:0042221 response to chemical stimulus
1.89 2.24e-02 GO:0009893 positive regulation of metabolic process
2.05 2.98e-02 GO:0032879 regulation of localization
3.83 3.09e-02 GO:0010035 response to inorganic substance
2.02 3.13e-02 GO:0010646 regulation of cell communication
5.95 3.13e-02 GO:0006639 acylglycerol metabolic process
2.09 3.28e-02 GO:0031328 positive regulation of cellular biosynthetic process
3.00 3.71e-02 GO:0044271 cellular nitrogen compound biosynthetic process
5.80 3.85e-02 GO:0006638 neutral lipid metabolic process
2.23 4.71e-02 GO:0051049 regulation of transport
38.16 4.73e-02 GO:0034380 high-density lipoprotein particle assembly
2.10 4.89e-02 GO:0051173 positive regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.41 6.01e-15 GO:0044424 intracellular part
1.54 6.38e-15 GO:0005737 cytoplasm
1.39 1.36e-14 GO:0005622 intracellular
1.47 2.61e-14 GO:0043226 organelle
1.46 2.14e-13 GO:0043229 intracellular organelle
1.71 2.17e-13 GO:0044444 cytoplasmic part
1.51 2.29e-13 GO:0043227 membrane-bounded organelle
1.50 8.88e-13 GO:0043231 intracellular membrane-bounded organelle
1.18 7.17e-08 GO:0005623 cell
1.18 7.17e-08 GO:0044464 cell part
2.20 1.02e-06 GO:0005829 cytosol
1.63 8.47e-06 GO:0071944 cell periphery
1.51 1.13e-05 GO:0005634 nucleus
1.56 2.52e-05 GO:0044422 organelle part
1.60 3.73e-05 GO:0005886 plasma membrane
1.55 5.40e-05 GO:0044446 intracellular organelle part
2.97 3.38e-04 GO:0005768 endosome
1.68 7.85e-04 GO:0043228 non-membrane-bounded organelle
1.68 7.85e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.56 9.03e-04 GO:0032991 macromolecular complex
2.92 2.99e-03 GO:0005730 nucleolus
1.71 8.95e-03 GO:0044459 plasma membrane part
1.54 9.90e-03 GO:0043234 protein complex
1.94 1.20e-02 GO:0042995 cell projection
1.72 1.29e-02 GO:0031974 membrane-enclosed lumen
1.73 1.36e-02 GO:0070013 intracellular organelle lumen
1.72 1.43e-02 GO:0043233 organelle lumen
1.69 1.84e-02 GO:0044428 nuclear part
1.77 2.02e-02 GO:0031981 nuclear lumen
1.23 4.16e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment p-value GO term description
1.71 8.81e-14 GO:0005515 protein binding
1.36 3.61e-11 GO:0005488 binding
2.32 3.60e-04 GO:0022892 substrate-specific transporter activity
2.40 4.20e-04 GO:0042802 identical protein binding
2.15 6.73e-04 GO:0005215 transporter activity
3.84 3.32e-03 GO:0043566 structure-specific DNA binding
2.93 1.08e-02 GO:0016563 transcription activator activity
2.18 1.15e-02 GO:0022891 substrate-specific transmembrane transporter activity
2.69 1.45e-02 GO:0008289 lipid binding
2.09 1.49e-02 GO:0022857 transmembrane transporter activity
2.16 1.85e-02 GO:0001071 nucleic acid binding transcription factor activity
2.16 1.85e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
4.93 3.05e-02 GO:0046943 carboxylic acid transmembrane transporter activity
4.82 3.60e-02 GO:0005342 organic acid transmembrane transporter activity
2.13 3.86e-02 GO:0046983 protein dimerization activity