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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BACH1_NFE2_NFE2L2

Z-value: 4.19

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.11 BTB domain and CNC homolog 1
ENSG00000123405.9 nuclear factor, erythroid 2
ENSG00000116044.11 nuclear factor, erythroid 2 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L2hg19_v2_chr2_-_178128199_178128245-0.661.5e-03Click!
BACH1hg19_v2_chr21_+_30671690_30671762-0.661.6e-03Click!
NFE2hg19_v2_chr12_-_54694807_546949050.077.6e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
3.2 9.6 GO:0042660 positive regulation of cell fate specification(GO:0042660)
1.8 7.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.6 4.8 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
1.4 5.7 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
1.4 4.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.3 3.8 GO:0071418 cellular response to amine stimulus(GO:0071418)
1.3 7.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.2 16.8 GO:0018298 protein-chromophore linkage(GO:0018298)
1.1 5.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.1 10.7 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.9 5.4 GO:0070541 response to platinum ion(GO:0070541)
0.9 4.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.8 3.3 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.8 8.8 GO:0030259 lipid glycosylation(GO:0030259)
0.8 6.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.8 10.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.7 10.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7 4.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.6 2.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.6 3.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.6 9.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.6 1.7 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.6 10.6 GO:0038203 TORC2 signaling(GO:0038203)
0.5 1.6 GO:0003032 detection of oxygen(GO:0003032)
0.5 1.6 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.5 2.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 2.0 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.5 4.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 5.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.5 1.9 GO:1990502 dense core granule maturation(GO:1990502)
0.5 6.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.5 3.7 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.5 1.4 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.4 4.0 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.8 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 8.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 19.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.4 2.7 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 5.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 3.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 1.5 GO:1904106 protein localization to microvillus(GO:1904106)
0.4 1.5 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.3 3.7 GO:0006528 asparagine metabolic process(GO:0006528)
0.3 5.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 1.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.3 2.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.3 6.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 2.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.3 1.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 1.8 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.3 34.7 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.3 1.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 28.9 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.3 2.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.3 2.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 1.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.3 1.8 GO:0060356 leucine import(GO:0060356)
0.3 1.8 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 1.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 5.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 1.4 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 0.7 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 3.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 0.9 GO:0090410 malonate catabolic process(GO:0090410)
0.2 1.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 4.1 GO:0015886 heme transport(GO:0015886)
0.2 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.2 0.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.2 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.2 1.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.9 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.7 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 2.7 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.2 1.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 7.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 2.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 3.0 GO:0051601 exocyst localization(GO:0051601)
0.1 3.1 GO:0033197 response to vitamin E(GO:0033197)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.5 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 1.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 6.0 GO:0072348 sulfur compound transport(GO:0072348)
0.1 1.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 1.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.8 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 1.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 6.7 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 3.5 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 3.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 3.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 4.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 1.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.4 GO:0038183 bile acid signaling pathway(GO:0038183)
0.1 2.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 3.4 GO:0043486 histone exchange(GO:0043486)
0.1 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 1.0 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 3.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 4.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.9 GO:0097264 self proteolysis(GO:0097264)
0.0 1.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 1.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 18.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 1.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 3.0 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0060068 vagina development(GO:0060068)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 2.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 10.9 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.7 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.2 GO:0009887 organ morphogenesis(GO:0009887)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 2.7 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 1.3 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 1.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 3.4 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 2.0 GO:0007015 actin filament organization(GO:0007015)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.5 6.1 GO:0044753 amphisome(GO:0044753)
1.4 4.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.4 16.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 4.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.9 7.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.8 3.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.6 15.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 6.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 3.1 GO:0035061 interchromatin granule(GO:0035061)
0.4 3.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 10.6 GO:0031932 TORC2 complex(GO:0031932)
0.4 1.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 3.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 9.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 3.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 9.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 5.2 GO:0030667 secretory granule membrane(GO:0030667)
0.2 4.2 GO:0000812 Swr1 complex(GO:0000812)
0.2 5.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 8.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 4.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:0045160 myosin I complex(GO:0045160)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0000502 proteasome complex(GO:0000502)
0.1 1.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.0 GO:0032437 cuticular plate(GO:0032437)
0.1 9.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.3 GO:0097227 sperm annulus(GO:0097227)
0.1 1.1 GO:0031298 replication fork protection complex(GO:0031298)
0.1 10.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 3.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 4.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 16.9 GO:0072562 blood microparticle(GO:0072562)
0.1 3.0 GO:0000145 exocyst(GO:0000145)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 4.8 GO:0016235 aggresome(GO:0016235)
0.1 6.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 3.4 GO:0008305 integrin complex(GO:0008305)
0.1 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 4.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 12.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 2.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 5.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.5 GO:0032420 stereocilium(GO:0032420)
0.0 3.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 3.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 7.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 11.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0019862 IgA binding(GO:0019862)
5.1 15.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
4.4 17.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
4.0 12.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
3.7 11.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
3.1 15.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
2.1 10.5 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
1.8 8.8 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
1.7 6.7 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.6 4.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.4 4.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
1.4 5.4 GO:0004325 ferrochelatase activity(GO:0004325)
1.3 3.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.3 3.8 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.8 3.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.8 2.5 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.7 4.7 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.7 8.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 3.0 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.6 1.8 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.6 10.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 17.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 4.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.5 3.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.5 1.4 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 1.4 GO:0097689 iron channel activity(GO:0097689)
0.4 1.8 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 4.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 5.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.4 3.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.7 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.4 1.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.4 15.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 1.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.3 2.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 0.9 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 1.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.8 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.3 7.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 2.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 1.5 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 0.7 GO:0031626 beta-endorphin binding(GO:0031626)
0.2 0.9 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.2 4.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 1.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 6.0 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.2 1.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 5.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 3.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.0 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 6.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 5.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 8.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.8 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 4.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 5.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 6.2 GO:0016209 antioxidant activity(GO:0016209)
0.1 1.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 9.6 GO:0097110 scaffold protein binding(GO:0097110)
0.1 3.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 13.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 1.3 GO:0015245 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 1.0 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 7.5 GO:0002039 p53 binding(GO:0002039)
0.1 3.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 3.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.7 GO:0030507 spectrin binding(GO:0030507)
0.1 3.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 9.7 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 4.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 22.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 3.1 GO:0000149 SNARE binding(GO:0000149)
0.0 5.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.5 GO:0046966 cytoskeletal adaptor activity(GO:0008093) thyroid hormone receptor binding(GO:0046966)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 2.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 22.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 18.2 PID TNF PATHWAY TNF receptor signaling pathway
0.2 4.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 9.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 11.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 13.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 7.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 6.9 PID AURORA B PATHWAY Aurora B signaling
0.1 4.6 PID AURORA A PATHWAY Aurora A signaling
0.1 3.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 8.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 10.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.7 PID E2F PATHWAY E2F transcription factor network
0.0 1.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 2.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 15.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.8 33.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 6.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 6.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 7.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 34.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 8.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 11.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 14.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 6.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 4.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 13.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.4 REACTOME OPSINS Genes involved in Opsins
0.1 4.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 7.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 3.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 4.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 4.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 6.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 3.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 3.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 4.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.7 REACTOME TRANSLATION Genes involved in Translation
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions