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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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ISMARA results avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

ISMARA - Integrated System for Motif Actitivity Response Analysis is a free online tool that recognizes most important transcription factors that are changing their activity in a set of samples.

Original results

Sample Condition
3-9-mock1-13_S20Mock_treated_A549_cells_IAV_control
3-9-mock2-14_S1Mock_treated_A549_cells_IAV_control
3-9-wt1-15_S2IAV_infected_A549_cells
3-9-wt2-16_S16IAV_infected_A549_cells
CoV002-CoV2-1-indexG4_S4SARS-CoV-2_infected_A549_cells
CoV002-CoV2-2-indexG5_S5SARS-CoV-2_infected_A549_cells
CoV002-CoV2-3-indexG6_S6SARS-CoV-2_infected_A549_cells
CoV002-mock1-indexG1_S1Mock_treated_A549_cells_SC2_control
CoV002-mock2-indexG2_S2Mock_treated_A549_cells_SC2_control
CoV002-mock3-indexG3_S3Mock_treated_A549_cells_SC2_control
SARS004-CoV2-1_S4SARS-CoV-2_infected_NHBE_cells
SARS004-CoV2-2_S5SARS-CoV-2_infected_NHBE_cells
SARS004-CoV2-3_S6SARS-CoV-2_infected_NHBE_cells
SARS004-mock-1_S1Mock_treated_NHBE_cells
SARS004-mock-2_S2Mock_treated_NHBE_cells
SARS004-mock-3_S3Mock_treated_NHBE_cells
svRNA184-mock-1-indexF1_S13Mock_treated_A549_cells_RSV_control
svRNA184-mock-3-indexF3_S15Mock_treated_A549_cells_RSV_control
svRNA184-RSV-1-indexF4_S16RSV_infected_A549_cells
svRNA184-RSV-3-indexH9_S18RSV_infected_A549_cells

All motifs sorted by activity significance

Motif name Z-value Associated genes Profile Logo
ZEB1 14.44 small profile SeqLogo of ZEB1
YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ 10.98 small profile SeqLogo of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
ZNF711_TFAP2A_TFAP2D 10.24 small profile SeqLogo of ZNF711_TFAP2A_TFAP2D
HNF1A_HNF1B 8.91 small profile SeqLogo of HNF1A_HNF1B
E2F7_E2F1 8.68 small profile SeqLogo of E2F7_E2F1
E2F2_E2F5 8.58 small profile SeqLogo of E2F2_E2F5
NRF1 8.17 small profile SeqLogo of NRF1
TBP 8.00 small profile SeqLogo of TBP
KLF16_SP2 7.55 small profile SeqLogo of KLF16_SP2
IRF2_STAT2_IRF8_IRF1 7.52 small profile SeqLogo of IRF2_STAT2_IRF8_IRF1
SP4_PML 6.61 small profile SeqLogo of SP4_PML
TFDP1 6.55 small profile SeqLogo of TFDP1
TP63 6.51 small profile SeqLogo of TP63
KLF1 6.35 small profile SeqLogo of KLF1
MXI1_MYC_MYCN 6.30 small profile SeqLogo of MXI1_MYC_MYCN
FOXM1_TBL1XR1 6.17 small profile SeqLogo of FOXM1_TBL1XR1
FOSL1 5.92 small profile SeqLogo of FOSL1
PITX1 5.77 small profile SeqLogo of PITX1
ESRRA_ESR2 5.49 small profile SeqLogo of ESRRA_ESR2
TAF1 5.36 small profile SeqLogo of TAF1
SP1 5.36 small profile SeqLogo of SP1
ZBTB33_CHD2 5.25 small profile SeqLogo of ZBTB33_CHD2
PLAGL1 5.12 small profile SeqLogo of PLAGL1
ZNF143 4.97 small profile SeqLogo of ZNF143
SOX3_SOX2 4.87 small profile SeqLogo of SOX3_SOX2
WRNIP1 4.80 small profile SeqLogo of WRNIP1
RFX3_RFX2 4.61 small profile SeqLogo of RFX3_RFX2
MYF6 4.58 small profile SeqLogo of MYF6
ZNF263 4.44 small profile SeqLogo of ZNF263
MYB 4.37 small profile SeqLogo of MYB
TEAD3_TEAD1 4.35 small profile SeqLogo of TEAD3_TEAD1
E2F3 4.29 small profile SeqLogo of E2F3
NFIX_NFIB 4.19 small profile SeqLogo of NFIX_NFIB
BACH1_NFE2_NFE2L2 4.19 small profile SeqLogo of BACH1_NFE2_NFE2L2
TFAP2B 4.19 small profile SeqLogo of TFAP2B
ELK4_ETV5_ELK1_ELK3_ELF4 4.15 small profile SeqLogo of ELK4_ETV5_ELK1_ELK3_ELF4
PBX3 4.13 small profile SeqLogo of PBX3
BARHL1 4.09 small profile SeqLogo of BARHL1
SMAD1 4.00 small profile SeqLogo of SMAD1
ELF3_EHF 3.91 small profile SeqLogo of ELF3_EHF
YY1_YY2 3.87 small profile SeqLogo of YY1_YY2
BPTF 3.85 small profile SeqLogo of BPTF
SP3 3.79 small profile SeqLogo of SP3
CTCF_CTCFL 3.78 small profile SeqLogo of CTCF_CTCFL
KLF8 3.75 small profile SeqLogo of KLF8
MEIS2 3.75 small profile SeqLogo of MEIS2
CXXC1 3.74 small profile SeqLogo of CXXC1
ZNF148 3.71 small profile SeqLogo of ZNF148
FLI1 3.70 small profile SeqLogo of FLI1
E2F6 3.70 small profile SeqLogo of E2F6
RFX7_RFX4_RFX1 3.70 small profile SeqLogo of RFX7_RFX4_RFX1
HOXB4_LHX9 3.67 small profile SeqLogo of HOXB4_LHX9
CEBPA 3.63 small profile SeqLogo of CEBPA
PAX5 3.62 small profile SeqLogo of PAX5
TFAP2C 3.57 small profile SeqLogo of TFAP2C
GRHL1 3.55 small profile SeqLogo of GRHL1
E2F4 3.51 small profile SeqLogo of E2F4
ELF2_GABPA_ELF5 3.50 small profile SeqLogo of ELF2_GABPA_ELF5
CREB1 3.44 small profile SeqLogo of CREB1
EBF1 3.44 small profile SeqLogo of EBF1
RREB1 3.44 small profile SeqLogo of RREB1
NFIA 3.40 small profile SeqLogo of NFIA
JDP2 3.39 small profile SeqLogo of JDP2
GATA3 3.35 small profile SeqLogo of GATA3
GMEB2 3.33 small profile SeqLogo of GMEB2
GLIS2 3.31 small profile SeqLogo of GLIS2
ZNF384 3.30 small profile SeqLogo of ZNF384
PATZ1_KLF4 3.29 small profile SeqLogo of PATZ1_KLF4
REST 3.27 small profile SeqLogo of REST
GLI3 3.22 small profile SeqLogo of GLI3
HNF4A 3.16 small profile SeqLogo of HNF4A
MYBL2 3.13 small profile SeqLogo of MYBL2
AGCACCA 3.12 small profile SeqLogo of AGCACCA
IRF9 3.11 small profile SeqLogo of IRF9
EGR1_EGR4 3.09 small profile SeqLogo of EGR1_EGR4
HIC2 3.08 small profile SeqLogo of HIC2
SOX13_SOX12 3.06 small profile SeqLogo of SOX13_SOX12
RARA 3.04 small profile SeqLogo of RARA
GAGGUAG 3.00 small profile SeqLogo of GAGGUAG
HOXC10_HOXD13 2.97 small profile SeqLogo of HOXC10_HOXD13
MECP2 2.93 small profile SeqLogo of MECP2
SMAD4 2.90 small profile SeqLogo of SMAD4
XBP1 2.89 small profile SeqLogo of XBP1
SIN3A_CHD1 2.84 small profile SeqLogo of SIN3A_CHD1
SRF 2.83 small profile SeqLogo of SRF
WT1_MTF1_ZBTB7B 2.79 small profile SeqLogo of WT1_MTF1_ZBTB7B
ZFX 2.78 small profile SeqLogo of ZFX
STAT1_STAT3_BCL6 2.78 small profile SeqLogo of STAT1_STAT3_BCL6
KLF6 2.77 small profile SeqLogo of KLF6
TLX2 2.75 small profile SeqLogo of TLX2
ERG 2.75 small profile SeqLogo of ERG
TFAP4_MSC 2.75 small profile SeqLogo of TFAP4_MSC
NR3C1 2.73 small profile SeqLogo of NR3C1
ARNT 2.73 small profile SeqLogo of ARNT
SOX10_SOX15 2.66 small profile SeqLogo of SOX10_SOX15
TFCP2L1 2.65 small profile SeqLogo of TFCP2L1
ID4_TCF4_SNAI2 2.65 small profile SeqLogo of ID4_TCF4_SNAI2
GCM2 2.64 small profile SeqLogo of GCM2
NFE2L1 2.63 small profile SeqLogo of NFE2L1
MYBL1 2.61 small profile SeqLogo of MYBL1
MAFB 2.61 small profile SeqLogo of MAFB
POU3F2 2.58 small profile SeqLogo of POU3F2
MAZ_ZNF281_GTF2F1 2.56 small profile SeqLogo of MAZ_ZNF281_GTF2F1
CUX1 2.55 small profile SeqLogo of CUX1
TCF7L2 2.54 small profile SeqLogo of TCF7L2
SPIB 2.54 small profile SeqLogo of SPIB
HOXB3 2.51 small profile SeqLogo of HOXB3
DPRX 2.51 small profile SeqLogo of DPRX
IRF6_IRF4_IRF5 2.51 small profile SeqLogo of IRF6_IRF4_IRF5
EPAS1_BCL3 2.50 small profile SeqLogo of EPAS1_BCL3
BATF 2.49 small profile SeqLogo of BATF
SP100 2.49 small profile SeqLogo of SP100
TAL1 2.48 small profile SeqLogo of TAL1
ZBTB6 2.47 small profile SeqLogo of ZBTB6
CLOCK 2.47 small profile SeqLogo of CLOCK
MEF2D_MEF2A 2.47 small profile SeqLogo of MEF2D_MEF2A
BARHL2 2.43 small profile SeqLogo of BARHL2
HES1 2.42 small profile SeqLogo of HES1
FOSL2_SMARCC1 2.41 small profile SeqLogo of FOSL2_SMARCC1
IRF3 2.41 small profile SeqLogo of IRF3
RUNX1_RUNX2 2.41 small profile SeqLogo of RUNX1_RUNX2
TCF3_MYOG 2.38 small profile SeqLogo of TCF3_MYOG
KLF14_SP8 2.36 small profile SeqLogo of KLF14_SP8
E2F8 2.33 small profile SeqLogo of E2F8
IKZF1 2.32 small profile SeqLogo of IKZF1
RUNX3_BCL11A 2.32 small profile SeqLogo of RUNX3_BCL11A
NR2F1 2.31 small profile SeqLogo of NR2F1
VDR 2.29 small profile SeqLogo of VDR
ZNF740_ZNF219 2.28 small profile SeqLogo of ZNF740_ZNF219
PITX3 2.26 small profile SeqLogo of PITX3
NFKB1 2.25 small profile SeqLogo of NFKB1
ESR1 2.24 small profile SeqLogo of ESR1
SPDEF 2.24 small profile SeqLogo of SPDEF
AAAGUGC 2.24 small profile SeqLogo of AAAGUGC
TLX1_NFIC 2.22 small profile SeqLogo of TLX1_NFIC
ZNF524 2.21 small profile SeqLogo of ZNF524
NKX1-2_RAX 2.17 small profile SeqLogo of NKX1-2_RAX
RCOR1_MTA3 2.17 small profile SeqLogo of RCOR1_MTA3
MLX_USF2_USF1_PAX2 2.17 small profile SeqLogo of MLX_USF2_USF1_PAX2
NR1H2 2.16 small profile SeqLogo of NR1H2
IKZF2 2.15 small profile SeqLogo of IKZF2
EZH2 2.14 small profile SeqLogo of EZH2
CCCUGAG 2.13 small profile SeqLogo of CCCUGAG
HMGA1 2.13 small profile SeqLogo of HMGA1
GLI2 2.12 small profile SeqLogo of GLI2
CUX2 2.12 small profile SeqLogo of CUX2
TEAD4 2.11 small profile SeqLogo of TEAD4
NKX2-2 2.09 small profile SeqLogo of NKX2-2
ZBTB12 2.09 small profile SeqLogo of ZBTB12
HOXA6 2.08 small profile SeqLogo of HOXA6
HOXC9 2.04 small profile SeqLogo of HOXC9
NR4A3 2.03 small profile SeqLogo of NR4A3
UAAGGCA 2.02 small profile SeqLogo of UAAGGCA
TP73 2.01 small profile SeqLogo of TP73
EBF3 2.00 small profile SeqLogo of EBF3
POU2F2_POU3F1 1.99 small profile SeqLogo of POU2F2_POU3F1
CEBPG 1.99 small profile SeqLogo of CEBPG
SOX9 1.99 small profile SeqLogo of SOX9
RHOXF1 1.98 small profile SeqLogo of RHOXF1
TCF12_ASCL2 1.98 small profile SeqLogo of TCF12_ASCL2
FOXJ2 1.97 small profile SeqLogo of FOXJ2
HOXA1 1.94 small profile SeqLogo of HOXA1
HSFY2 1.94 small profile SeqLogo of HSFY2
TWIST1_SNAI1 1.93 small profile SeqLogo of TWIST1_SNAI1
HOXB6_PRRX2 1.93 small profile SeqLogo of HOXB6_PRRX2
AAUACUG 1.93 small profile SeqLogo of AAUACUG
FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 1.92 small profile SeqLogo of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
SPI1 1.91 small profile SeqLogo of SPI1
SIX5_SMARCC2_HCFC1 1.91 small profile SeqLogo of SIX5_SMARCC2_HCFC1
HIVEP1 1.90 small profile SeqLogo of HIVEP1
GATA2 1.90 small profile SeqLogo of GATA2
ACAUUCA 1.89 small profile SeqLogo of ACAUUCA
ZBTB16 1.89 small profile SeqLogo of ZBTB16
FOXA1 1.89 small profile SeqLogo of FOXA1
CEBPE_CEBPD 1.88 small profile SeqLogo of CEBPE_CEBPD
LMX1B_MNX1_RAX2 1.88 small profile SeqLogo of LMX1B_MNX1_RAX2
ETV6 1.87 small profile SeqLogo of ETV6
GUAAACA 1.86 small profile SeqLogo of GUAAACA
HOXC8 1.85 small profile SeqLogo of HOXC8
CPEB1 1.84 small profile SeqLogo of CPEB1
IRX3 1.84 small profile SeqLogo of IRX3
MYOD1 1.84 small profile SeqLogo of MYOD1
KLF12 1.83 small profile SeqLogo of KLF12
FOXN1 1.83 small profile SeqLogo of FOXN1
CENPB 1.82 small profile SeqLogo of CENPB
POU4F1_POU4F3 1.81 small profile SeqLogo of POU4F1_POU4F3
FOXL1 1.80 small profile SeqLogo of FOXL1
GGAAUGU 1.80 small profile SeqLogo of GGAAUGU
AACACUG 1.79 small profile SeqLogo of AACACUG
GMEB1 1.78 small profile SeqLogo of GMEB1
NOTO_VSX2_DLX2_DLX6_NKX6-1 1.78 small profile SeqLogo of NOTO_VSX2_DLX2_DLX6_NKX6-1
HIC1 1.77 small profile SeqLogo of HIC1
JUND 1.77 small profile SeqLogo of JUND
ZNF784 1.77 small profile SeqLogo of ZNF784
RELA 1.74 small profile SeqLogo of RELA
POU2F1 1.73 small profile SeqLogo of POU2F1
NFKB2 1.73 small profile SeqLogo of NFKB2
UAUUGCU 1.71 small profile SeqLogo of UAUUGCU
NR1I2 1.71 small profile SeqLogo of NR1I2
AGUGGUU 1.71 small profile SeqLogo of AGUGGUU
SOX17 1.70 small profile SeqLogo of SOX17
CUUUGGU 1.69 small profile SeqLogo of CUUUGGU
NHLH1 1.66 small profile SeqLogo of NHLH1
NR5A2 1.66 small profile SeqLogo of NR5A2
LEF1 1.65 small profile SeqLogo of LEF1
STAT5B 1.65 small profile SeqLogo of STAT5B
ETV1_ERF_FEV_ELF1 1.64 small profile SeqLogo of ETV1_ERF_FEV_ELF1
ZBTB14 1.64 small profile SeqLogo of ZBTB14
UACAGUA 1.64 small profile SeqLogo of UACAGUA
BHLHE40 1.63 small profile SeqLogo of BHLHE40
ZBTB18 1.62 small profile SeqLogo of ZBTB18
HOMEZ 1.61 small profile SeqLogo of HOMEZ
SOX6 1.60 small profile SeqLogo of SOX6
DUXA 1.59 small profile SeqLogo of DUXA
ETS1 1.59 small profile SeqLogo of ETS1
GGCUCAG 1.59 small profile SeqLogo of GGCUCAG
RXRG 1.58 small profile SeqLogo of RXRG
ATF5 1.57 small profile SeqLogo of ATF5
AGUGCUU 1.57 small profile SeqLogo of AGUGCUU
MBD2 1.57 small profile SeqLogo of MBD2
ZIC3_ZIC4 1.56 small profile SeqLogo of ZIC3_ZIC4
NKX2-1 1.54 small profile SeqLogo of NKX2-1
VAX1_GSX2 1.53 small profile SeqLogo of VAX1_GSX2
EMX2 1.53 small profile SeqLogo of EMX2
PPARG 1.53 small profile SeqLogo of PPARG
NR2E3 1.52 small profile SeqLogo of NR2E3
DDIT3 1.51 small profile SeqLogo of DDIT3
ATF6 1.50 small profile SeqLogo of ATF6
ACAGUAC 1.50 small profile SeqLogo of ACAGUAC
NFATC1 1.50 small profile SeqLogo of NFATC1
UAGUGUU 1.50
small profile
GUGCAAA 1.50 small profile SeqLogo of GUGCAAA
STAT4 1.48 small profile SeqLogo of STAT4
AGGUAGU 1.47 small profile SeqLogo of AGGUAGU
FOXQ1 1.47 small profile SeqLogo of FOXQ1
UGCAUAG 1.46 small profile SeqLogo of UGCAUAG
HOXC12_HOXD12 1.44 small profile SeqLogo of HOXC12_HOXD12
AGCAGCA 1.44 small profile SeqLogo of AGCAGCA
CBFB 1.44 small profile SeqLogo of CBFB
DLX4_HOXD8 1.43 small profile SeqLogo of DLX4_HOXD8
SMAD3 1.43 small profile SeqLogo of SMAD3
MLXIPL 1.42 small profile SeqLogo of MLXIPL
HNF4G 1.42 small profile SeqLogo of HNF4G
ATF4 1.42 small profile SeqLogo of ATF4
HINFP 1.42 small profile SeqLogo of HINFP
ZIC1 1.41 small profile SeqLogo of ZIC1
CREB5_CREM_JUNB 1.41 small profile SeqLogo of CREB5_CREM_JUNB
AGUGCAA 1.41 small profile SeqLogo of AGUGCAA
KLF13 1.41 small profile SeqLogo of KLF13
HOXB2_UNCX_HOXD3 1.41 small profile SeqLogo of HOXB2_UNCX_HOXD3
CDX2 1.40 small profile SeqLogo of CDX2
PRDM14 1.40 small profile SeqLogo of PRDM14
ZKSCAN1 1.40 small profile SeqLogo of ZKSCAN1
SREBF2 1.38 small profile SeqLogo of SREBF2
GATA5 1.38 small profile SeqLogo of GATA5
PAX1_PAX9 1.38 small profile SeqLogo of PAX1_PAX9
MEIS1 1.38 small profile SeqLogo of MEIS1
GGCAGUG 1.38