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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DLX4_HOXD8

Z-value: 1.43

Motif logo

Transcription factors associated with DLX4_HOXD8

Gene Symbol Gene ID Gene Info
ENSG00000108813.9 distal-less homeobox 4
ENSG00000175879.7 homeobox D8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD8hg19_v2_chr2_+_176994408_176994641-0.252.8e-01Click!
DLX4hg19_v2_chr17_+_48046671_480466970.068.1e-01Click!

Activity profile of DLX4_HOXD8 motif

Sorted Z-values of DLX4_HOXD8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX4_HOXD8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4 1.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.0 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.3 0.8 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.3 3.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 0.8 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.7 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.2 0.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.6 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.2 1.2 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 2.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0030070 insulin processing(GO:0030070)
0.2 0.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 1.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 1.7 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.2 0.5 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.9 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.5 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 1.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 1.0 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 2.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.6 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 7.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 1.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 2.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.1 GO:0046782 regulation of viral transcription(GO:0046782)
0.1 0.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 0.4 GO:2000006 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 0.9 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.9 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.4 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.6 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.3 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.1 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.2 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 4.4 GO:0070206 protein trimerization(GO:0070206)
0.1 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.2 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.3 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.3 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 1.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 1.2 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.5 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.0 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 1.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0034368 macromolecular complex remodeling(GO:0034367) protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 1.1 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:2001188 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188)
0.0 0.0 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 1.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.2 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 2.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.1 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.7 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0016073 snRNA metabolic process(GO:0016073) ncRNA transcription(GO:0098781)
0.0 0.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.4 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0015744 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.0 2.9 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.1 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.0 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0048371 vacuolar phosphate transport(GO:0007037) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.0 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.0 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 1.1 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0061053 somite development(GO:0061053)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 2.0 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.7 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.0 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 1.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.1 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0055007 cardiac muscle cell differentiation(GO:0055007)
0.0 0.0 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0021954 central nervous system neuron development(GO:0021954)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 1.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 2.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:1990742 microvesicle(GO:1990742)
0.1 1.4 GO:0036128 CatSper complex(GO:0036128)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.1 GO:0000806 Y chromosome(GO:0000806)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 2.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0044215 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 7.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.2 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 3.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 2.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 3.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 6.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0030666 endocytic vesicle membrane(GO:0030666) phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.0 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.3 1.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 1.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.2 GO:0015211 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleoside transmembrane transporter activity(GO:0015211) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.0 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 7.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.1 0.5 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.4 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.3 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.2 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.3 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.1 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.2 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 2.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 1.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.2 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.6 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 1.0 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0015563 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.2 GO:0019959 interleukin-8 receptor activity(GO:0004918) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.0 2.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 7.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) extracellular matrix constituent, lubricant activity(GO:0030197) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.0 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 3.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 11.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 5.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import