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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOXC1

Z-value: 1.21

Motif logo

Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
ENSG00000054598.9 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg38_v1_chr6_+_1609890_1609932-0.334.3e-01Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_96584920 2.81 ENST00000521590.5
syndecan 2
chr8_-_107497909 2.14 ENST00000517746.6
angiopoietin 1
chr8_-_107498041 2.10 ENST00000297450.7
angiopoietin 1
chr8_-_92095215 1.82 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1 partner transcriptional co-repressor 1
chr17_-_19387170 1.66 ENST00000395592.6
ENST00000299610.5
microfibril associated protein 4
chr11_+_114060204 1.55 ENST00000683318.1
zinc finger and BTB domain containing 16
chr11_+_114059755 1.54 ENST00000684295.1
zinc finger and BTB domain containing 16
chr2_+_33134579 1.11 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr9_-_86947496 1.10 ENST00000298743.9
growth arrest specific 1
chr2_+_33134620 1.08 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr9_-_92424427 1.08 ENST00000375550.5
osteomodulin
chr8_+_103372388 1.03 ENST00000520337.1
collagen triple helix repeat containing 1
chr1_+_222928415 0.96 ENST00000284476.7
dispatched RND transporter family member 1
chr2_-_189179754 0.95 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr13_+_32031706 0.92 ENST00000542859.6
FRY microtubule binding protein
chr8_-_92095627 0.92 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr9_-_20382461 0.91 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr6_-_152168291 0.89 ENST00000354674.5
spectrin repeat containing nuclear envelope protein 1
chr6_-_152168349 0.88 ENST00000539504.5
spectrin repeat containing nuclear envelope protein 1
chr4_-_185775271 0.86 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr18_-_54959391 0.86 ENST00000591504.6
coiled-coil domain containing 68
chr5_-_111756245 0.84 ENST00000447165.6
neuronal regeneration related protein
chr10_+_68109433 0.81 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr2_+_127418420 0.74 ENST00000234071.8
ENST00000429925.5
ENST00000442644.5
protein C, inactivator of coagulation factors Va and VIIIa
chr3_-_114624193 0.70 ENST00000481632.5
zinc finger and BTB domain containing 20
chr12_-_29783798 0.69 ENST00000552618.5
ENST00000551659.5
ENST00000539277.6
transmembrane O-mannosyltransferase targeting cadherins 1
chr3_-_195583931 0.67 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr1_+_197917355 0.64 ENST00000367388.4
ENST00000367387.6
LIM homeobox 9
chr18_-_28177016 0.63 ENST00000430882.6
cadherin 2
chr2_-_144516154 0.63 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr8_-_92095598 0.62 ENST00000520724.5
ENST00000518844.5
RUNX1 partner transcriptional co-repressor 1
chr2_-_144516397 0.62 ENST00000638128.1
zinc finger E-box binding homeobox 2
chr8_-_19682576 0.61 ENST00000332246.10
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_-_39424966 0.61 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr5_-_39425187 0.59 ENST00000545653.5
DAB adaptor protein 2
chr12_-_92145838 0.57 ENST00000256015.5
BTG anti-proliferation factor 1
chr7_-_13988863 0.56 ENST00000405358.8
ETS variant transcription factor 1
chr13_+_31945826 0.53 ENST00000647500.1
FRY microtubule binding protein
chrX_+_22032301 0.53 ENST00000379374.5
phosphate regulating endopeptidase homolog X-linked
chr2_+_165239388 0.50 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr3_+_155080307 0.50 ENST00000360490.7
membrane metalloendopeptidase
chr2_+_165239432 0.48 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chr6_+_108560906 0.47 ENST00000406360.2
forkhead box O3
chr3_-_187736493 0.47 ENST00000232014.8
BCL6 transcription repressor
chr3_-_114758940 0.47 ENST00000464560.5
zinc finger and BTB domain containing 20
chr6_-_56851888 0.47 ENST00000312431.10
ENST00000520645.5
dystonin
chr3_-_114759115 0.46 ENST00000471418.5
zinc finger and BTB domain containing 20
chrX_+_101488044 0.45 ENST00000423738.4
armadillo repeat containing X-linked 4
chr3_-_187745460 0.45 ENST00000406870.7
BCL6 transcription repressor
chr7_-_13989658 0.43 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr8_+_69492793 0.43 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr6_+_101398788 0.43 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
glutamate ionotropic receptor kainate type subunit 2
chr19_+_18007182 0.42 ENST00000595712.6
arrestin domain containing 2
chr2_+_209653171 0.41 ENST00000447185.5
microtubule associated protein 2
chr6_-_31684040 0.40 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr5_-_124746630 0.40 ENST00000513986.2
zinc finger protein 608
chr17_+_59331633 0.39 ENST00000312655.9
yippee like 2
chr4_+_128811311 0.38 ENST00000413543.6
jade family PHD finger 1
chr2_-_223602284 0.38 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr15_-_55365231 0.37 ENST00000568543.1
cell cycle progression 1
chr12_+_59596010 0.36 ENST00000547379.6
ENST00000552432.5
solute carrier family 16 member 7
chrX_+_86714623 0.36 ENST00000484479.1
dachshund family transcription factor 2
chr3_+_114294020 0.34 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr1_+_18631513 0.33 ENST00000400661.3
paired box 7
chr5_+_141192330 0.33 ENST00000239446.6
protocadherin beta 10
chr3_+_69763726 0.32 ENST00000448226.9
melanocyte inducing transcription factor
chr4_+_85475131 0.32 ENST00000395184.6
Rho GTPase activating protein 24
chr4_-_88823306 0.31 ENST00000395002.6
family with sequence similarity 13 member A
chr19_-_36032799 0.30 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr5_-_128339191 0.28 ENST00000507835.5
fibrillin 2
chr15_-_78077657 0.28 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr14_-_92106607 0.28 ENST00000340660.10
ENST00000393287.9
ENST00000429774.6
ENST00000545170.5
ENST00000620536.4
ENST00000621269.4
ataxin 3
chr2_-_2326378 0.28 ENST00000647618.1
myelin transcription factor 1 like
chr14_-_60724300 0.27 ENST00000556952.3
ENST00000216513.5
SIX homeobox 4
chr10_-_24721866 0.27 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr8_+_74824526 0.27 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr9_+_17906563 0.27 ENST00000680146.1
ADAMTS like 1
chr12_+_130953898 0.26 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr6_+_83853576 0.26 ENST00000369687.2
ripply transcriptional repressor 2
chr3_-_57292676 0.26 ENST00000389601.3
ENST00000487349.6
ankyrin repeat and SOCS box containing 14
chr3_+_37990768 0.25 ENST00000383759.7
villin like
chr1_+_18631006 0.25 ENST00000375375.7
paired box 7
chr3_-_127736329 0.25 ENST00000398101.7
monoglyceride lipase
chr5_+_143812161 0.25 ENST00000289448.4
histocompatibility minor HB-1
chr9_-_5185628 0.24 ENST00000381641.4
ENST00000649639.1
insulin like 6
chr10_+_52314272 0.24 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chrX_-_8171267 0.24 ENST00000317103.5
variable charge X-linked 2
chr11_-_63144221 0.24 ENST00000417740.5
ENST00000612278.4
ENST00000326192.5
solute carrier family 22 member 24
chr7_-_105876575 0.23 ENST00000318724.8
ENST00000419735.8
ataxin 7 like 1
chr7_+_80602200 0.23 ENST00000534394.5
CD36 molecule
chr3_-_16482850 0.23 ENST00000432519.5
raftlin, lipid raft linker 1
chr6_+_118894144 0.23 ENST00000229595.6
anti-silencing function 1A histone chaperone
chr7_+_80602150 0.23 ENST00000309881.11
CD36 molecule
chr6_-_53061740 0.22 ENST00000350082.10
ENST00000356971.3
ENST00000676107.1
ciliogenesis associated kinase 1
chr6_-_110815408 0.22 ENST00000368911.8
cyclin dependent kinase 19
chr8_-_71362054 0.22 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr3_-_71583683 0.21 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr10_+_91162958 0.21 ENST00000614189.4
polycomb group ring finger 5
chr18_-_63158208 0.21 ENST00000678301.1
BCL2 apoptosis regulator
chr8_-_71361860 0.21 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr2_+_44275457 0.21 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr3_-_142149515 0.21 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
transcription factor Dp-2
chr11_-_6419051 0.20 ENST00000299402.10
ENST00000532020.2
ENST00000609360.6
ENST00000389906.6
amyloid beta precursor protein binding family B member 1
chr11_-_6419394 0.20 ENST00000311051.7
amyloid beta precursor protein binding family B member 1
chr15_+_67125707 0.20 ENST00000540846.6
SMAD family member 3
chr13_-_74133892 0.20 ENST00000377669.7
Kruppel like factor 12
chr9_-_107489754 0.20 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr14_-_92106535 0.20 ENST00000526872.3
ENST00000532032.5
ENST00000506466.5
ENST00000554592.5
ENST00000555381.5
ENST00000553491.5
ENST00000556220.5
ENST00000557311.6
ENST00000617719.4
ENST00000554672.6
ENST00000644486.2
ENST00000502250.5
ENST00000503767.5
ataxin 3
chr12_+_98645218 0.19 ENST00000551964.6
ENST00000333991.5
ENST00000357310.5
ENST00000359972.6
apoptotic peptidase activating factor 1
chr7_+_151341764 0.19 ENST00000413040.7
ENST00000470229.6
ENST00000568733.6
negative regulator of ubiquitin like proteins 1
chr14_+_50560137 0.19 ENST00000358385.12
atlastin GTPase 1
chr2_-_2326210 0.19 ENST00000647755.1
myelin transcription factor 1 like
chr1_+_207104226 0.19 ENST00000367070.8
complement component 4 binding protein alpha
chr7_+_80369547 0.18 ENST00000435819.5
CD36 molecule
chr19_+_35533436 0.18 ENST00000222286.9
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_+_61077219 0.18 ENST00000407417.7
nuclear factor I A
chr19_-_51751854 0.18 ENST00000304748.5
ENST00000595042.5
formyl peptide receptor 1
chr5_-_131796921 0.18 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr2_+_85753984 0.17 ENST00000306279.4
atonal bHLH transcription factor 8
chr7_-_139777774 0.17 ENST00000428878.6
homeodomain interacting protein kinase 2
chr5_-_131797030 0.17 ENST00000615660.4
folliculin interacting protein 1
chr15_-_41230697 0.17 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
exonuclease 3'-5' domain containing 1
chr11_+_73308237 0.16 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr12_+_92702843 0.16 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr5_+_160009113 0.15 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
tetratricopeptide repeat domain 1
chr15_+_96325935 0.15 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr20_-_35529618 0.15 ENST00000246199.5
ENST00000424444.1
ENST00000374345.8
ENST00000444723.3
chromosome 20 open reading frame 173
chr1_-_19484635 0.15 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr2_+_161160420 0.15 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr13_-_61415508 0.15 ENST00000409204.4
protocadherin 20
chr9_-_83817632 0.15 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr2_+_44275473 0.15 ENST00000260649.11
solute carrier family 3 member 1
chr2_-_27663594 0.14 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr6_+_138773747 0.14 ENST00000617445.5
coiled-coil domain containing 28A
chr2_-_27663817 0.14 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr3_-_71583592 0.14 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr8_-_144529048 0.14 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
chromosome 8 open reading frame 82
chr13_+_35476740 0.14 ENST00000537702.5
neurobeachin
chr4_-_151325488 0.14 ENST00000604030.7
SH3 domain containing 19
chr7_-_105876477 0.14 ENST00000478915.1
ataxin 7 like 1
chr5_+_40841308 0.14 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr17_+_59565598 0.14 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr3_-_71583713 0.13 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr1_-_150010675 0.13 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr12_+_92702983 0.13 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chrX_+_54920796 0.13 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr4_-_98657635 0.12 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr12_+_15956585 0.12 ENST00000526530.1
deoxyribose-phosphate aldolase
chr10_-_116273009 0.12 ENST00000439649.8
ENST00000369234.5
ENST00000682194.1
ENST00000355422.11
GDNF family receptor alpha 1
chr3_+_141738263 0.12 ENST00000480908.1
ENST00000393000.3
ENST00000273480.4
ring finger protein 7
chr10_-_30999469 0.12 ENST00000538351.6
zinc finger protein 438
chr10_+_110871903 0.12 ENST00000280154.12
programmed cell death 4
chr1_+_246566422 0.12 ENST00000366513.9
ENST00000366512.7
consortin, connexin sorting protein
chr3_-_71581540 0.11 ENST00000650068.1
forkhead box P1
chr1_-_159714581 0.11 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr12_-_10098940 0.11 ENST00000420265.2
C-type lectin domain family 1 member A
chr3_-_71582096 0.11 ENST00000648895.1
forkhead box P1
chr5_-_146878595 0.11 ENST00000394409.7
protein phosphatase 2 regulatory subunit Bbeta
chr5_+_112976757 0.11 ENST00000389063.3
decapping mRNA 2
chr2_-_182242031 0.11 ENST00000358139.6
phosphodiesterase 1A
chr6_-_42048648 0.11 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr4_+_85475167 0.10 ENST00000503995.5
Rho GTPase activating protein 24
chr1_-_150697128 0.10 ENST00000427665.1
ENST00000271732.8
golgi phosphoprotein 3 like
chr9_+_6413191 0.10 ENST00000276893.10
ubiquitin like with PHD and ring finger domains 2
chr6_+_10528326 0.10 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr10_+_110225955 0.10 ENST00000239007.11
MAX interactor 1, dimerization protein
chr19_-_36032625 0.10 ENST00000593074.5
CAP-Gly domain containing linker protein 3
chr2_+_142877653 0.10 ENST00000375773.6
ENST00000409512.5
ENST00000264170.9
ENST00000410015.6
kynureninase
chr10_-_67838173 0.10 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr11_-_47426419 0.10 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr3_-_71581829 0.09 ENST00000649610.1
forkhead box P1
chr11_+_8019193 0.09 ENST00000534099.5
TUB bipartite transcription factor
chr11_-_47426216 0.09 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chr7_+_120950763 0.09 ENST00000339121.9
ENST00000315870.10
ENST00000445699.5
inhibitor of growth family member 3
chr11_+_46617521 0.09 ENST00000580238.5
ENST00000581416.5
ENST00000529655.5
ENST00000533325.5
ENST00000683050.1
ENST00000581438.5
ENST00000583249.5
ENST00000530500.5
ENST00000526508.5
ENST00000578626.5
ENST00000577256.5
ENST00000524625.5
ENST00000582547.5
ENST00000359513.8
ENST00000528494.5
autophagy related 13
chr11_-_78341876 0.09 ENST00000340149.6
GRB2 associated binding protein 2
chr12_+_10212867 0.08 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr10_+_110871789 0.08 ENST00000393104.6
programmed cell death 4
chr20_-_18467023 0.08 ENST00000262547.9
double zinc ribbon and ankyrin repeat domains 1
chr10_-_116272266 0.08 ENST00000682489.1
ENST00000369236.5
GDNF family receptor alpha 1
chr12_+_53985138 0.08 ENST00000303460.5
homeobox C10
chr11_-_46617170 0.08 ENST00000326737.3
harbinger transposase derived 1
chr17_+_73233202 0.08 ENST00000582793.1
chromosome 17 open reading frame 80
chr3_-_71132099 0.08 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr10_-_103153609 0.08 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr3_-_139476508 0.07 ENST00000232217.6
retinol binding protein 2
chr5_+_136132772 0.07 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr1_-_151459169 0.07 ENST00000368863.6
ENST00000409503.5
ENST00000491586.5
ENST00000533351.5
pogo transposable element derived with ZNF domain
chr15_+_75347431 0.07 ENST00000567657.5
nei like DNA glycosylase 1
chr11_-_127000762 0.07 ENST00000525144.7
kirre like nephrin family adhesion molecule 3
chr5_+_76875177 0.07 ENST00000613039.1
S100 calcium binding protein Z
chr12_-_98644733 0.07 ENST00000299157.5
ENST00000393042.3
IKBKB interacting protein
chr1_+_23691742 0.07 ENST00000374550.8
ENST00000643754.2
ribosomal protein L11
chr22_+_24432119 0.07 ENST00000472248.5
ENST00000610595.4
ENST00000618076.3
ENST00000436735.1
adenosine A2a receptor
chr19_-_50637939 0.07 ENST00000338916.8
synaptotagmin 3
chr5_-_36301883 0.07 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr16_+_8621679 0.07 ENST00000563958.5
ENST00000381920.8
ENST00000564554.1
methyltransferase like 22
chrX_-_19670983 0.07 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr3_-_157503375 0.07 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr6_-_99994173 0.07 ENST00000281806.7
ENST00000369212.2
melanin concentrating hormone receptor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.5 3.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.5 2.8 GO:0008218 bioluminescence(GO:0008218)
0.4 1.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 1.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 1.0 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.3 0.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 2.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.7 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 0.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.6 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.2 0.9 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 1.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 1.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.5 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.6 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.3 GO:0061055 myotome development(GO:0061055)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 1.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.9 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 3.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.9 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.7 GO:0071953 elastic fiber(GO:0071953)
0.1 2.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.9 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 4.2 GO:0005902 microvillus(GO:0005902)
0.0 4.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0050436 microfibril binding(GO:0050436)
0.2 3.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.1 1.8 GO:0005521 lamin binding(GO:0005521)
0.0 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.0 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 3.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0070064 tau protein binding(GO:0048156) proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0001221 transcription cofactor binding(GO:0001221)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors