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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NHLH1

Z-value: 0.85

Motif logo

Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
ENSG00000171786.6 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg38_v1_chr1_+_160367061_1603670780.147.4e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_41124178 1.65 ENST00000394014.2
keratin associated protein 4-12
chr12_-_52493250 1.17 ENST00000330722.7
keratin 6A
chr7_-_140062841 1.10 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr17_-_41118369 0.82 ENST00000391413.4
keratin associated protein 4-11
chr12_-_52473798 0.81 ENST00000252250.7
keratin 6C
chr16_+_22814154 0.79 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr17_-_41140487 0.75 ENST00000345847.4
keratin associated protein 4-6
chr20_+_59604527 0.68 ENST00000371015.6
phosphatase and actin regulator 3
chr5_+_53480619 0.66 ENST00000396947.7
ENST00000256759.8
follistatin
chr6_+_30880780 0.65 ENST00000460944.6
ENST00000324771.12
discoidin domain receptor tyrosine kinase 1
chr1_+_81800906 0.64 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr6_+_150143018 0.59 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr5_+_167754918 0.57 ENST00000519204.5
teneurin transmembrane protein 2
chr9_-_23821275 0.56 ENST00000380110.8
ELAV like RNA binding protein 2
chr11_+_394196 0.53 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr9_-_27529705 0.52 ENST00000262244.6
MOB kinase activator 3B
chr8_-_124728273 0.49 ENST00000325064.9
ENST00000518547.6
MTSS I-BAR domain containing 1
chr9_-_23826231 0.46 ENST00000397312.7
ELAV like RNA binding protein 2
chr8_+_85463997 0.42 ENST00000285379.10
carbonic anhydrase 2
chr18_+_11689210 0.41 ENST00000334049.11
G protein subunit alpha L
chr6_+_125153649 0.41 ENST00000304877.17
ENST00000368402.9
ENST00000368388.6
ENST00000534000.6
TPD52 like 1
chr22_+_44702186 0.40 ENST00000336985.11
ENST00000403696.5
ENST00000457960.5
ENST00000361473.9
proline rich 5
PRR5-ARHGAP8 readthrough
chr20_+_46008900 0.39 ENST00000372330.3
matrix metallopeptidase 9
chr4_-_36244438 0.38 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_1882902 0.37 ENST00000231357.7
iroquois homeobox 4
chr17_+_41105332 0.36 ENST00000391415.1
ENST00000617453.1
keratin associated protein 4-9
chr6_+_125153793 0.35 ENST00000527711.5
TPD52 like 1
chr6_+_125154189 0.35 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chr17_+_41226648 0.34 ENST00000377721.3
keratin associated protein 9-2
chr8_+_24914942 0.34 ENST00000433454.3
neurofilament medium
chr12_-_66678934 0.33 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr22_+_39994926 0.32 ENST00000333407.11
family with sequence similarity 83 member F
chr1_-_37808168 0.31 ENST00000373044.3
yrdC N6-threonylcarbamoyltransferase domain containing
chr19_+_45340760 0.31 ENST00000585434.5
kinesin light chain 3
chr2_+_68774782 0.31 ENST00000409030.7
ENST00000409220.5
Rho GTPase activating protein 25
chr1_+_13583762 0.31 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr19_+_45340736 0.30 ENST00000391946.7
kinesin light chain 3
chr19_+_44777860 0.30 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr1_-_209806124 0.30 ENST00000367021.8
ENST00000542854.5
interferon regulatory factor 6
chr9_-_137054016 0.29 ENST00000312665.7
ENST00000355097.7
ectonucleoside triphosphate diphosphohydrolase 2
chr15_+_40252888 0.28 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr4_+_88378733 0.27 ENST00000273960.7
ENST00000380265.9
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr16_+_57639518 0.26 ENST00000540164.6
ENST00000568531.5
adhesion G protein-coupled receptor G1
chr17_+_82735551 0.26 ENST00000300784.8
fructosamine 3 kinase
chr17_-_41184895 0.26 ENST00000620667.1
ENST00000398472.2
keratin associated protein 4-1
chr14_-_53956811 0.26 ENST00000559087.5
ENST00000245451.9
bone morphogenetic protein 4
chr4_+_88378842 0.26 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr2_+_197705353 0.25 ENST00000282276.8
methionyl-tRNA synthetase 2, mitochondrial
chr9_-_23826299 0.25 ENST00000380117.5
ELAV like RNA binding protein 2
chr7_+_20330678 0.25 ENST00000537992.5
integrin subunit beta 8
chr16_+_67431112 0.24 ENST00000326152.6
hydroxysteroid 11-beta dehydrogenase 2
chr5_+_56815534 0.24 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr1_-_6602885 0.24 ENST00000377663.3
kelch like family member 21
chr1_+_156284299 0.23 ENST00000456810.1
ENST00000405535.3
transmembrane protein 79
chr4_-_138242325 0.23 ENST00000280612.9
solute carrier family 7 member 11
chr19_+_45340774 0.23 ENST00000589837.5
kinesin light chain 3
chr2_-_234497035 0.23 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr1_-_6602859 0.23 ENST00000377658.8
kelch like family member 21
chr17_-_41168219 0.23 ENST00000391356.4
keratin associated protein 4-3
chr8_+_144148027 0.23 ENST00000423230.6
maestro heat like repeat family member 1
chr17_-_35795592 0.23 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr15_+_40358207 0.23 ENST00000267889.5
dispatched RND transporter family member 2
chr22_-_37486357 0.22 ENST00000356998.8
ENST00000416983.7
ENST00000424765.2
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_+_58255433 0.22 ENST00000635997.1
NEDD4 like E3 ubiquitin protein ligase
chr20_-_14337602 0.22 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr4_-_80073057 0.21 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr20_+_63861498 0.21 ENST00000369916.5
abhydrolase domain containing 16B
chr2_+_195657179 0.21 ENST00000359634.10
solute carrier family 39 member 10
chr4_+_74445126 0.21 ENST00000395748.8
amphiregulin
chr7_+_129144691 0.20 ENST00000486685.3
tetraspanin 33
chr2_-_96145431 0.20 ENST00000288943.5
dual specificity phosphatase 2
chr6_-_81752671 0.20 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr22_+_44677044 0.20 ENST00000006251.11
proline rich 5
chr4_+_74445302 0.20 ENST00000502307.1
amphiregulin
chr7_-_727611 0.19 ENST00000403562.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr17_+_57085092 0.19 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr4_-_80073170 0.19 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr8_+_24913752 0.19 ENST00000518131.5
ENST00000221166.10
ENST00000437366.2
neurofilament medium
chr5_+_69492767 0.18 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr17_+_75516514 0.18 ENST00000333213.11
ENST00000545228.3
ENST00000680999.1
tRNA splicing endonuclease subunit 54
chr12_+_41188301 0.18 ENST00000402685.7
PDZ domain containing ring finger 4
chr1_+_32741779 0.18 ENST00000401073.7
KIAA1522
chr8_-_130016395 0.18 ENST00000523509.5
CYFIP related Rac1 interactor B
chr8_-_130016414 0.18 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr22_-_24593038 0.18 ENST00000318753.13
leucine rich repeat containing 75B
chrX_-_85379659 0.17 ENST00000262753.9
POF1B actin binding protein
chr17_+_41237998 0.17 ENST00000254072.7
keratin associated protein 9-8
chr9_+_98807619 0.17 ENST00000375011.4
polypeptide N-acetylgalactosaminyltransferase 12
chr6_-_30744537 0.17 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr12_+_49623543 0.17 ENST00000548825.7
ENST00000261897.5
pre-mRNA processing factor 40 homolog B
chr9_-_123268538 0.16 ENST00000360998.3
ENST00000348403.10
spermatid perinuclear RNA binding protein
chr19_-_2051224 0.16 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr17_-_17206264 0.16 ENST00000321560.4
phospholipase D family member 6
chr16_+_2964216 0.16 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr1_+_156154371 0.16 ENST00000368282.1
semaphorin 4A
chr14_+_23372809 0.16 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr8_+_97775775 0.16 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr6_+_18155399 0.16 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chr16_+_1706163 0.16 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
mitogen-activated protein kinase 8 interacting protein 3
chr5_-_95284535 0.16 ENST00000515393.5
multiple C2 and transmembrane domain containing 1
chr8_-_38150943 0.16 ENST00000276449.9
steroidogenic acute regulatory protein
chr8_+_144509049 0.16 ENST00000301327.5
major facilitator superfamily domain containing 3
chr15_-_52295792 0.15 ENST00000261839.12
myosin VC
chr14_+_69879408 0.15 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr1_+_31413187 0.15 ENST00000373709.8
serine incorporator 2
chr8_+_141128612 0.15 ENST00000518347.5
ENST00000262585.6
ENST00000520986.5
ENST00000523058.5
ENST00000518668.5
DENN domain containing 3
chr16_+_23835946 0.15 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr14_+_63204859 0.15 ENST00000555125.1
ras homolog family member J
chr8_+_141128581 0.15 ENST00000519811.6
DENN domain containing 3
chr16_+_2817230 0.15 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr1_+_14945775 0.15 ENST00000400797.3
kazrin, periplakin interacting protein
chr18_+_46334197 0.15 ENST00000588679.1
ENST00000543885.2
ring finger protein 165
chr12_+_122021850 0.14 ENST00000261822.5
BAF chromatin remodeling complex subunit BCL7A
chr19_-_38253238 0.14 ENST00000587515.5
protein phosphatase 1 regulatory inhibitor subunit 14A
chr8_+_97775829 0.14 ENST00000517924.5
lysosomal protein transmembrane 4 beta
chr19_-_17448664 0.14 ENST00000341130.6
transmembrane protein 221
chr1_+_202348727 0.14 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr17_-_32877106 0.14 ENST00000318217.10
ENST00000579584.5
ENST00000583621.1
myosin ID
chr12_+_7155867 0.14 ENST00000535313.2
ENST00000331148.5
calsyntenin 3
chr10_-_101588126 0.14 ENST00000339310.7
ENST00000299206.8
ENST00000413344.5
ENST00000429502.1
ENST00000430045.1
ENST00000370172.5
ENST00000370162.8
ENST00000628479.2
DNA polymerase lambda
chr12_+_6946468 0.14 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr3_-_45146351 0.14 ENST00000296129.6
ENST00000425231.2
CUB domain containing protein 1
chr2_+_232697362 0.13 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr17_+_49575828 0.13 ENST00000328741.6
neurexophilin 3
chr2_+_127645864 0.13 ENST00000544369.5
G protein-coupled receptor 17
chr4_-_80073465 0.13 ENST00000404191.5
ANTXR cell adhesion molecule 2
chr6_+_14117764 0.13 ENST00000379153.4
CD83 molecule
chr14_+_32934383 0.13 ENST00000551634.6
neuronal PAS domain protein 3
chr11_-_64166102 0.13 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr16_+_11345429 0.13 ENST00000576027.1
ENST00000312499.6
ENST00000648619.1
RecQ mediated genome instability 2
chr16_+_74999312 0.13 ENST00000566250.5
ENST00000567962.5
zinc and ring finger 1
chr8_-_143815649 0.13 ENST00000356994.7
scribble planar cell polarity protein
chr12_+_109713817 0.12 ENST00000538780.2
family with sequence similarity 222 member A
chr2_+_48314637 0.12 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr2_-_73284431 0.12 ENST00000521871.5
ENST00000520530.3
F-box protein 41
chr8_+_127735597 0.12 ENST00000651626.1
MYC proto-oncogene, bHLH transcription factor
chr16_-_29926155 0.12 ENST00000567795.3
ENST00000568000.6
ENST00000561540.2
potassium channel tetramerization domain containing 13
chr14_+_70907661 0.12 ENST00000439984.7
pecanex 1
chr18_-_55586092 0.12 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr3_-_165837412 0.12 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr11_+_44726811 0.12 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr3_-_195909711 0.12 ENST00000333602.14
tyrosine kinase non receptor 2
chr15_+_50182215 0.12 ENST00000380902.8
solute carrier family 27 member 2
chr16_+_27402167 0.12 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr11_-_66958366 0.12 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr2_-_72147819 0.12 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr15_-_83284645 0.12 ENST00000345382.7
basonuclin 1
chr11_-_65606959 0.11 ENST00000532507.5
mitogen-activated protein kinase kinase kinase 11
chr3_-_133895753 0.11 ENST00000460865.3
RAB6B, member RAS oncogene family
chr6_+_142301926 0.11 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr17_-_28951443 0.11 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHD finger protein 12
chr11_+_67303476 0.11 ENST00000376757.9
ENST00000308298.11
slingshot protein phosphatase 3
chr10_+_122163426 0.11 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr18_+_46334007 0.11 ENST00000269439.12
ENST00000590330.1
ring finger protein 165
chr9_-_115118145 0.11 ENST00000350763.9
tenascin C
chr9_-_115118198 0.11 ENST00000534839.1
ENST00000535648.5
tenascin C
chr2_+_195656734 0.11 ENST00000409086.7
solute carrier family 39 member 10
chr10_+_122163590 0.11 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr7_-_77416300 0.11 ENST00000257626.12
gamma-secretase activating protein
chr12_+_119989869 0.11 ENST00000397558.6
BICD family like cargo adaptor 1
chr2_+_232870284 0.11 ENST00000331342.4
secondary ossification center associated regulator of chondrocyte maturation
chr8_-_97277890 0.11 ENST00000322128.5
TSPY like 5
chr16_-_90019414 0.11 ENST00000002501.11
dysbindin domain containing 1
chr19_+_39196956 0.11 ENST00000339852.5
NCCRP1, F-box associated domain containing
chr22_+_25742141 0.11 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr1_+_178513103 0.11 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
testis expressed 35
chr20_+_50731571 0.11 ENST00000371610.7
par-6 family cell polarity regulator beta
chr7_+_151114597 0.11 ENST00000335367.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_2530256 0.10 ENST00000378453.4
hes family bHLH transcription factor 5
chr10_+_122163672 0.10 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chrX_+_85244075 0.10 ENST00000276123.7
zinc finger protein 711
chr10_+_69451456 0.10 ENST00000373290.7
tetraspanin 15
chr1_-_21622509 0.10 ENST00000374761.6
RAP1 GTPase activating protein
chr1_+_20589044 0.10 ENST00000375071.4
cytidine deaminase
chr7_+_20330893 0.10 ENST00000222573.5
integrin subunit beta 8
chr8_+_103298836 0.10 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr16_-_90019821 0.10 ENST00000568838.2
dysbindin domain containing 1
chr5_-_16936231 0.10 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr17_-_7393404 0.10 ENST00000575434.4
phospholipid scramblase 3
chr18_+_10454584 0.10 ENST00000355285.10
APC down-regulated 1
chr19_+_7595830 0.10 ENST00000160298.9
ENST00000446248.4
calmodulin regulated spectrin associated protein family member 3
chr14_-_24263162 0.10 ENST00000206765.11
ENST00000544573.5
transglutaminase 1
chr3_-_33659441 0.10 ENST00000650653.1
ENST00000480013.6
cytoplasmic linker associated protein 2
chr21_+_33070133 0.10 ENST00000382348.2
oligodendrocyte transcription factor 1
chr13_-_36131286 0.10 ENST00000255448.8
ENST00000379892.4
doublecortin like kinase 1
chr5_+_127290785 0.10 ENST00000503335.7
multiple EGF like domains 10
chr1_-_3796478 0.10 ENST00000378251.3
leucine rich repeat containing 47
chr17_+_7435416 0.09 ENST00000323206.2
ENST00000396568.1
transmembrane protein 102
chr3_-_197183806 0.09 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr11_+_7576975 0.09 ENST00000684215.1
ENST00000650027.1
PPFIA binding protein 2
chr3_+_5187697 0.09 ENST00000256497.9
ER degradation enhancing alpha-mannosidase like protein 1
chr14_+_30874497 0.09 ENST00000216361.9
cochlin
chr8_+_135457442 0.09 ENST00000355849.10
KH RNA binding domain containing, signal transduction associated 3
chr7_-_139036017 0.09 ENST00000275766.2
zinc finger CCCH-type containing, antiviral 1 like
chr5_+_76819022 0.09 ENST00000296677.5
F2R like trypsin receptor 1
chr3_-_197183963 0.09 ENST00000653795.1
discs large MAGUK scaffold protein 1
chr19_-_17334844 0.09 ENST00000159087.7
anoctamin 8
chr15_+_50182188 0.09 ENST00000267842.10
solute carrier family 27 member 2
chr1_-_156677400 0.09 ENST00000368223.4
nestin
chr10_-_124744280 0.09 ENST00000337318.8
family with sequence similarity 53 member B

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.2 GO:0070859 phthalate metabolic process(GO:0018963) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.4 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.4 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.1 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0043652 skeletal muscle satellite cell activation(GO:0014719) engulfment of apoptotic cell(GO:0043652)
0.0 0.4 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 3.3 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0034034 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0048865 stem cell fate commitment(GO:0048865)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.0 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 5.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol