Motif ID: Alx4

Z-value: 0.912


Transcription factors associated with Alx4:

Gene SymbolEntrez IDGene Name
Alx4 ENSMUSG00000040310.6 Alx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx4mm10_v2_chr2_+_93642307_936423880.253.8e-01Click!


Activity profile for motif Alx4.

activity profile for motif Alx4


Sorted Z-values histogram for motif Alx4

Sorted Z-values for motif Alx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Alx4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_11604828 2.409 ENSMUST00000025582.4
 Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr6_-_136875794 2.323 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr7_-_45103747 2.322 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr5_-_43981757 2.199 ENSMUST00000061299.7
 Fgfbp1
fibroblast growth factor binding protein 1
chr8_+_94152607 1.602 ENSMUST00000034211.8
 Mt3
metallothionein 3
chr2_+_125136692 1.582 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr7_-_126676357 1.516 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
 Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr7_-_126676428 1.477 ENSMUST00000106373.1
 Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr13_+_76579670 1.386 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr11_-_102946688 1.386 ENSMUST00000057849.5
 C1ql1
complement component 1, q subcomponent-like 1
chr6_+_124304646 1.329 ENSMUST00000112541.2
ENSMUST00000032234.2
 Cd163

CD163 antigen

chr9_-_123678782 1.228 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr9_-_123678873 1.200 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chrX_+_73483602 1.184 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr2_-_5063996 1.144 ENSMUST00000114996.1
 Optn
optineurin
chr10_-_8886033 1.127 ENSMUST00000015449.5
 Sash1
SAM and SH3 domain containing 1
chr4_+_147492417 1.076 ENSMUST00000105721.2
 Gm13152
predicted gene 13152
chr12_+_38783503 1.057 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr1_-_152386675 1.056 ENSMUST00000015124.8
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr12_+_16653470 1.050 ENSMUST00000111064.1
 Ntsr2
neurotensin receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.0 GO:0051923 sulfation(GO:0051923)
0.4 2.4 GO:0036233 glycine import(GO:0036233)
0.6 2.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 2.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 2.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.3 2.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5 2.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 2.0 GO:0022900 electron transport chain(GO:0022900)
0.2 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.5 1.4 GO:0061743 motor learning(GO:0061743)
0.1 1.3 GO:0006953 acute-phase response(GO:0006953)
0.4 1.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.0 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.9 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.9 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.3 0.8 GO:0002940 tRNA N2-guanine methylation(GO:0002940)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0070469 respiratory chain(GO:0070469)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 1.4 GO:0044301 climbing fiber(GO:0044301)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.7 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 3.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.4 2.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 2.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8 2.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 2.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 1.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.2 0.9 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)