Motif ID: Arid5b

Z-value: 0.437


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_682787350.421.4e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_24680890 0.801 ENSMUST00000156453.2
 Cys1
cystin 1
chr15_-_13173607 0.774 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr10_-_109010955 0.693 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr9_+_112227443 0.637 ENSMUST00000161216.1
 2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr3_-_19264959 0.537 ENSMUST00000121951.1
 Pde7a
phosphodiesterase 7A
chr10_-_6980376 0.509 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr3_-_95882031 0.508 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr9_+_21196705 0.478 ENSMUST00000003395.9
 Pde4a
phosphodiesterase 4A, cAMP specific
chr15_-_44428303 0.461 ENSMUST00000038719.6
 Nudcd1
NudC domain containing 1
chr13_+_109685994 0.407 ENSMUST00000074103.5
 Pde4d
phosphodiesterase 4D, cAMP specific
chr1_-_31222604 0.374 ENSMUST00000127775.1
 4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr4_+_132638987 0.337 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
 Eya3




eyes absent 3 homolog (Drosophila)




chr4_-_129662442 0.333 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr8_-_119840522 0.327 ENSMUST00000168698.1
ENSMUST00000034285.6
 Cotl1

coactosin-like 1 (Dictyostelium)

chr9_-_45984816 0.323 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr9_+_87022014 0.309 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chr1_+_180568913 0.306 ENSMUST00000027777.6
 Parp1
poly (ADP-ribose) polymerase family, member 1
chr8_+_34115030 0.292 ENSMUST00000095345.3
 Mboat4
membrane bound O-acyltransferase domain containing 4
chr5_-_31697598 0.292 ENSMUST00000031018.7
 Rbks
ribokinase
chr3_+_95588990 0.285 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr16_+_32431225 0.272 ENSMUST00000115140.1
 Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr9_-_106789130 0.269 ENSMUST00000046502.5
 Rad54l2
RAD54 like 2 (S. cerevisiae)
chrX_-_157492280 0.267 ENSMUST00000112529.1
 Sms
spermine synthase
chr5_-_131538687 0.250 ENSMUST00000161374.1
 Auts2
autism susceptibility candidate 2
chr10_+_116143881 0.247 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr12_+_110601439 0.242 ENSMUST00000018851.7
 Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr1_+_163779575 0.197 ENSMUST00000027877.6
ENSMUST00000077642.5
 Kifap3

kinesin-associated protein 3

chr8_-_79399513 0.193 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
 Smad1


SMAD family member 1


chr15_+_37233036 0.191 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
 Grhl2


grainyhead-like 2 (Drosophila)


chr14_-_52213379 0.187 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr7_-_67645195 0.175 ENSMUST00000032775.5
ENSMUST00000053950.2
 Lrrc28

leucine rich repeat containing 28

chrX_+_47912387 0.175 ENSMUST00000001202.8
ENSMUST00000115020.1
 Ocrl

oculocerebrorenal syndrome of Lowe

chr12_-_91746020 0.164 ENSMUST00000166967.1
 Ston2
stonin 2
chr3_+_95588960 0.150 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr6_+_120666388 0.149 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr11_-_50827681 0.133 ENSMUST00000109135.2
 Zfp354c
zinc finger protein 354C
chr8_-_11008458 0.129 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr3_-_89998656 0.128 ENSMUST00000079724.4
 Hax1
HCLS1 associated X-1
chr6_+_97210689 0.124 ENSMUST00000044681.6
 Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr12_-_10900296 0.123 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr18_+_62662108 0.123 ENSMUST00000163259.1
 Gm17732
predicted gene, 17732
chr16_-_32247152 0.113 ENSMUST00000042732.5
 Fbxo45
F-box protein 45
chr18_+_23415400 0.112 ENSMUST00000115832.2
ENSMUST00000047954.7
 Dtna

dystrobrevin alpha

chr11_-_109298090 0.110 ENSMUST00000106704.2
 Rgs9
regulator of G-protein signaling 9
chr3_+_95588928 0.110 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like


chr10_+_127420867 0.087 ENSMUST00000064793.6
 R3hdm2
R3H domain containing 2
chr2_-_84678828 0.080 ENSMUST00000111665.1
 Tmx2
thioredoxin-related transmembrane protein 2
chrX_-_101222426 0.073 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr10_+_94576254 0.071 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr9_+_122117338 0.067 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase


chr4_+_43632185 0.066 ENSMUST00000107874.2
 Npr2
natriuretic peptide receptor 2
chr1_+_180330470 0.059 ENSMUST00000070181.6
 Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr4_+_122836236 0.053 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr10_-_14718191 0.044 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr13_+_21735055 0.043 ENSMUST00000087714.4
 Hist1h4j
histone cluster 1, H4j
chr2_+_76650264 0.040 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr7_-_101921186 0.029 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr11_-_32267547 0.026 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
 Nprl3


nitrogen permease regulator-like 3


chr4_-_150909428 0.024 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
 Park7


Parkinson disease (autosomal recessive, early onset) 7


chr4_+_43631935 0.018 ENSMUST00000030191.8
 Npr2
natriuretic peptide receptor 2
chr11_-_110251736 0.018 ENSMUST00000044003.7
 Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_+_84678396 0.016 ENSMUST00000102645.3
 Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr4_-_75278246 0.007 ENSMUST00000030103.8
 Tmem261
transmembrane protein 261

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0040009 regulation of growth rate(GO:0040009) protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0001842 neural fold formation(GO:0001842)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0090537 CERF complex(GO:0090537)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)