Motif ID: Arnt2

Z-value: 0.390


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.126.9e-01Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_54085542 1.613 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr13_+_13590402 0.754 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr14_-_63543931 0.689 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr10_-_63421739 0.632 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr4_+_101496648 0.616 ENSMUST00000106930.1
ENSMUST00000154120.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr17_-_46890405 0.598 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr11_+_107547925 0.498 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr1_-_52817503 0.489 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr13_+_118714678 0.439 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr9_-_86695897 0.436 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr4_-_41275091 0.341 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr1_+_87327044 0.295 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr12_-_59011996 0.282 ENSMUST00000021375.5
Sec23a
SEC23A (S. cerevisiae)
chr2_-_33371400 0.281 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr1_+_87327008 0.276 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr1_-_16619245 0.252 ENSMUST00000182984.1
ENSMUST00000182554.1
Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr1_-_58973421 0.240 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr18_+_31634374 0.207 ENSMUST00000025109.7
Sap130
Sin3A associated protein
chr18_+_31634368 0.205 ENSMUST00000178164.1
Sap130
Sin3A associated protein
chr5_-_115300957 0.199 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr4_-_48279544 0.195 ENSMUST00000030028.4
Erp44
endoplasmic reticulum protein 44
chr3_+_69721985 0.190 ENSMUST00000029358.8
Nmd3
NMD3 homolog (S. cerevisiae)
chr6_+_4601124 0.187 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr2_-_33371486 0.166 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr5_-_115300912 0.144 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr8_+_83900706 0.140 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1


latrophilin 1


chr15_-_38078842 0.124 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr1_-_52817643 0.119 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chrX_+_99136119 0.102 ENSMUST00000052839.6
Efnb1
ephrin B1
chr4_+_148041172 0.100 ENSMUST00000069604.8
Mthfr
5,10-methylenetetrahydrofolate reductase
chr1_+_87326997 0.093 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr19_+_43612299 0.091 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr1_+_59912972 0.083 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr7_-_45091713 0.062 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chrX_-_53269786 0.061 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr17_-_26508463 0.052 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr1_-_135258449 0.052 ENSMUST00000003135.7
Elf3
E74-like factor 3
chr8_-_124949165 0.048 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr11_+_43528759 0.029 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr9_-_108094459 0.028 ENSMUST00000081309.7
Apeh
acylpeptide hydrolase
chr1_+_58973521 0.016 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.1 0.4 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.0 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.4 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)