Motif ID: Ascl2

Z-value: 0.706


Transcription factors associated with Ascl2:

Gene SymbolEntrez IDGene Name
Ascl2 ENSMUSG00000009248.5 Ascl2



Activity profile for motif Ascl2.

activity profile for motif Ascl2


Sorted Z-values histogram for motif Ascl2

Sorted Z-values for motif Ascl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ascl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_45216671 0.758 ENSMUST00000134420.1
 Tead2
TEA domain family member 2
chr19_-_45560508 0.619 ENSMUST00000026239.6
 Poll
polymerase (DNA directed), lambda
chr2_+_32646586 0.538 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr15_-_78773452 0.471 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_103443653 0.414 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr1_+_120340569 0.402 ENSMUST00000037286.8
 C1ql2
complement component 1, q subcomponent-like 2
chr5_-_98030727 0.402 ENSMUST00000031281.9
 Antxr2
anthrax toxin receptor 2
chr12_+_53248677 0.401 ENSMUST00000101432.2
 Npas3
neuronal PAS domain protein 3
chr12_+_110279228 0.386 ENSMUST00000097228.4
 Dio3
deiodinase, iodothyronine type III
chrX_+_73483602 0.380 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr11_+_117809687 0.361 ENSMUST00000120928.1
ENSMUST00000175737.1
 Syngr2

synaptogyrin 2

chr11_-_114795888 0.347 ENSMUST00000000206.3
 Btbd17
BTB (POZ) domain containing 17
chr10_-_7212222 0.342 ENSMUST00000015346.5
 Cnksr3
Cnksr family member 3
chr15_+_102144362 0.340 ENSMUST00000023807.6
 Igfbp6
insulin-like growth factor binding protein 6
chr1_+_153665274 0.327 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr9_-_96437434 0.316 ENSMUST00000070500.2
 BC043934
cDNA sequence BC043934
chrX_+_101449078 0.315 ENSMUST00000033674.5
 Itgb1bp2
integrin beta 1 binding protein 2
chr7_+_45639964 0.312 ENSMUST00000148532.1
 Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr11_+_117809653 0.298 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr16_-_31314804 0.294 ENSMUST00000115230.1
ENSMUST00000130560.1
 Apod

apolipoprotein D


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.8 GO:0030903 notochord development(GO:0030903)
0.1 0.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.4 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.1 0.4 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 0.4 GO:0042711 maternal behavior(GO:0042711)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.3 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.3 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.5 GO:0005534 galactose binding(GO:0005534)
0.2 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)