Motif ID: Atf3

Z-value: 0.749


Transcription factors associated with Atf3:

Gene SymbolEntrez IDGene Name
Atf3 ENSMUSG00000026628.8 Atf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf3mm10_v2_chr1_-_191183244_191183340-0.312.8e-01Click!


Activity profile for motif Atf3.

activity profile for motif Atf3


Sorted Z-values histogram for motif Atf3

Sorted Z-values for motif Atf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 1.721 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr17_+_22689771 1.277 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr10_-_33995054 0.702 ENSMUST00000164429.1
 Gm17567
predicted gene, 17567
chr4_+_42735545 0.659 ENSMUST00000068158.3
 4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr6_-_149101506 0.632 ENSMUST00000127727.1
 Dennd5b
DENN/MADD domain containing 5B
chr10_+_69787431 0.616 ENSMUST00000183240.1
 Ank3
ankyrin 3, epithelial
chr4_-_11981265 0.526 ENSMUST00000098260.2
 Gm10604
predicted gene 10604
chr2_+_67748212 0.522 ENSMUST00000180887.1
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_+_21690766 0.493 ENSMUST00000097384.1
 Gm10509
predicted gene 10509
chr5_-_25223153 0.455 ENSMUST00000066954.1
 E130116L18Rik
RIKEN cDNA E130116L18 gene
chr2_-_5676046 0.417 ENSMUST00000114987.3
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_-_21961581 0.383 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
 Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr1_+_159737510 0.380 ENSMUST00000111669.3
 Tnr
tenascin R
chr8_+_117157972 0.366 ENSMUST00000064488.4
ENSMUST00000162997.1
 Gan

giant axonal neuropathy

chr16_+_21891969 0.363 ENSMUST00000042065.6
 Map3k13
mitogen-activated protein kinase kinase kinase 13
chr2_-_20943413 0.347 ENSMUST00000140230.1
 Arhgap21
Rho GTPase activating protein 21
chr17_-_83631892 0.342 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr1_-_21961942 0.339 ENSMUST00000115300.1
 Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr13_-_41273977 0.332 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr1_+_132506230 0.331 ENSMUST00000058167.1
 Tmem81
transmembrane protein 81

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 281 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 0.5 GO:0017085 response to insecticide(GO:0017085)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0007099 centriole replication(GO:0007099)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0030118 clathrin coat(GO:0030118)
0.0 0.8 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.4 GO:0072534 perineuronal net(GO:0072534)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 159 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.5 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)