Motif ID: Atf5

Z-value: 1.128


Transcription factors associated with Atf5:

Gene SymbolEntrez IDGene Name
Atf5 ENSMUSG00000038539.8 Atf5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44815658_44815682-0.544.6e-02Click!


Activity profile for motif Atf5.

activity profile for motif Atf5


Sorted Z-values histogram for motif Atf5

Sorted Z-values for motif Atf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209448 4.179 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr1_+_153665666 3.783 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr4_-_82705735 3.278 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chrX_+_41401304 3.161 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chrX_+_41401128 2.713 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_+_153665587 2.601 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 2.361 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr13_-_98206151 2.106 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chrX_+_41401476 1.945 ENSMUST00000165288.1
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr19_-_19001099 1.783 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr4_-_8239034 1.758 ENSMUST00000066674.7
Car8
carbonic anhydrase 8
chr1_-_172057573 1.477 ENSMUST00000059794.3
Nhlh1
nescient helix loop helix 1
chr1_+_32172711 1.396 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr5_-_24601961 1.367 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr14_-_12823031 1.217 ENSMUST00000067491.6
ENSMUST00000177814.1
ENSMUST00000112658.1
ENSMUST00000112657.2
Cadps



Ca2+-dependent secretion activator



chr14_+_12284198 1.164 ENSMUST00000112669.3
ENSMUST00000163392.1
3830406C13Rik

RIKEN cDNA 3830406C13 gene

chr2_+_124610573 1.065 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr5_+_137761680 1.024 ENSMUST00000110983.2
ENSMUST00000031738.4
Tsc22d4

TSC22 domain family, member 4

chr11_-_20112876 0.986 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr1_-_157256682 0.947 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 7.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.4 3.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.8 3.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 1.8 GO:0034436 glycoprotein transport(GO:0034436)
0.3 1.8 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.5 1.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 1.2 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 1.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.3 1.0 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 1.0 GO:0003281 ventricular septum development(GO:0003281)
0.2 0.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.3 0.8 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 0.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.7 7.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.1 7.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 3.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.6 1.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.6 1.8 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 1.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.7 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0035925 translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)