Motif ID: Atf6

Z-value: 0.815


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_1708677840.411.4e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 4.365 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr3_+_123267445 3.050 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chrY_-_1245753 2.522 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr4_+_125490688 2.482 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr6_-_126740151 1.501 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr6_-_136173492 1.426 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr13_+_93303757 1.421 ENSMUST00000109494.1
 Homer1
homer homolog 1 (Drosophila)
chrX_+_41401128 1.235 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr8_-_90908415 1.157 ENSMUST00000098517.1
 Gm6658
predicted gene 6658
chr3_+_104638658 1.144 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr5_-_89883321 1.069 ENSMUST00000163159.1
ENSMUST00000061427.5
 Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr6_+_77242644 1.047 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr14_-_26638183 1.023 ENSMUST00000166902.1
 4930570N19Rik
RIKEN cDNA 4930570N19 gene
chr4_-_142239356 1.018 ENSMUST00000036476.3
 Kazn
kazrin, periplakin interacting protein
chr3_+_103575231 1.005 ENSMUST00000121834.1
 Syt6
synaptotagmin VI
chr6_+_77242715 1.002 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr12_+_82616885 0.981 ENSMUST00000161801.1
 Rgs6
regulator of G-protein signaling 6
chr1_+_99772765 0.966 ENSMUST00000086738.3
 Cntnap5b
contactin associated protein-like 5B
chr7_-_126082406 0.943 ENSMUST00000073935.5
 Gsg1l
GSG1-like
chr3_+_103575275 0.922 ENSMUST00000090697.4
 Syt6
synaptotagmin VI

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 4.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 2.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.6 1.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 1.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 1.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2 1.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.0 GO:0031424 keratinization(GO:0031424)
0.3 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 0.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 0.7 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.7 GO:0006817 phosphate ion transport(GO:0006817)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.3 GO:0043034 costamere(GO:0043034)
0.2 2.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.3 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 2.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.3 2.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 2.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)