Motif ID: Atf7_E4f1

Z-value: 0.898

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E4f1mm10_v2_chr17_-_24455265_244553450.214.6e-01Click!
Atf7mm10_v2_chr15_-_102529025_1025290250.146.2e-01Click!


Activity profile for motif Atf7_E4f1.

activity profile for motif Atf7_E4f1


Sorted Z-values histogram for motif Atf7_E4f1

Sorted Z-values for motif Atf7_E4f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170009659 2.429 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr2_+_155276297 2.174 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr11_+_113619318 1.872 ENSMUST00000146390.2
ENSMUST00000106630.1
 Sstr2

somatostatin receptor 2

chr7_+_30413744 1.724 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr7_-_19629355 1.479 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
 Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr4_+_130107556 1.447 ENSMUST00000030563.5
 Pef1
penta-EF hand domain containing 1
chr1_+_95313607 1.370 ENSMUST00000059975.6
 Fam174a
family with sequence similarity 174, member A
chr5_-_124032214 1.254 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr12_-_69159109 1.218 ENSMUST00000037023.8
 Rps29
ribosomal protein S29
chr2_+_105668935 1.114 ENSMUST00000142772.1
 Pax6
paired box gene 6
chr3_+_67374116 1.001 ENSMUST00000061322.8
 Mlf1
myeloid leukemia factor 1
chr12_+_79130777 0.949 ENSMUST00000021550.6
 Arg2
arginase type II
chr19_-_5085483 0.939 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
 Tmem151a


transmembrane protein 151A


chr7_-_44496406 0.916 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
 Emc10



ER membrane protein complex subunit 10



chr11_+_101468164 0.908 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr8_+_45885479 0.903 ENSMUST00000034053.5
 Pdlim3
PDZ and LIM domain 3
chr3_+_67374091 0.901 ENSMUST00000077916.5
 Mlf1
myeloid leukemia factor 1
chr7_-_13034722 0.899 ENSMUST00000005711.4
 Chmp2a
charged multivesicular body protein 2A
chr11_-_6444352 0.893 ENSMUST00000093346.5
ENSMUST00000109737.2
 H2afv

H2A histone family, member V

chr4_-_107810948 0.892 ENSMUST00000097930.1
 B230314M03Rik
RIKEN cDNA B230314M03 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 161 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.3 2.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.4 1.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.3 1.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.9 GO:0030432 peristalsis(GO:0030432)
0.3 1.7 GO:2001204 regulation of osteoclast development(GO:2001204)
0.4 1.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 1.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.4 1.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 1.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 1.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 0.9 GO:0010958 regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
0.3 0.9 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.2 GO:0031514 motile cilium(GO:0031514)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.9 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 1.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.2 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)