Motif ID: Atoh1_Bhlhe23

Z-value: 0.583

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776900_1807769000.451.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_79456750 2.178 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr3_+_118430299 1.600 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr1_+_42697146 1.214 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr5_+_124194894 1.012 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr15_-_91191733 0.972 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr10_+_70204675 0.875 ENSMUST00000020090.1
2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr1_+_150392794 0.826 ENSMUST00000124973.2
Tpr
translocated promoter region
chr3_-_59220150 0.724 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_+_62046462 0.721 ENSMUST00000102735.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr16_+_43235856 0.694 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_56454871 0.693 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_-_92164666 0.693 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr2_+_62046580 0.687 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_62046623 0.667 ENSMUST00000112480.2
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr4_+_11579647 0.664 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr1_+_167618246 0.597 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr1_+_177444653 0.586 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr4_-_110292719 0.554 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_-_97747399 0.500 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_111864869 0.468 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chr3_-_84259812 0.437 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr13_-_97747373 0.390 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_+_37345338 0.361 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr6_-_12749193 0.358 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chrX_+_36328353 0.346 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr6_+_90462562 0.341 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr1_-_150392719 0.338 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr10_-_22149270 0.337 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr17_-_25792284 0.324 ENSMUST00000072735.7
Fam173a
family with sequence similarity 173, member A
chr17_-_6827990 0.320 ENSMUST00000181895.1
Gm2885
predicted gene 2885
chr1_+_6730051 0.314 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr16_+_43510267 0.296 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr2_+_150323702 0.293 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr9_+_66946057 0.292 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr1_-_155232710 0.291 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr7_-_90129339 0.270 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chrX_-_53608979 0.258 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr10_+_61175206 0.250 ENSMUST00000079235.5
Tbata
thymus, brain and testes associated
chr2_-_156180135 0.239 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr16_-_31314804 0.236 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr10_-_12923075 0.228 ENSMUST00000180529.1
B230208H11Rik
RIKEN cDNA B230208H11 gene
chr6_+_17743582 0.227 ENSMUST00000000674.6
ENSMUST00000077080.2
St7

suppression of tumorigenicity 7

chr14_+_28511344 0.225 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr5_+_129096740 0.225 ENSMUST00000056617.7
ENSMUST00000156437.1
Gpr133

G protein-coupled receptor 133

chr17_-_35074485 0.203 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr9_+_106281061 0.198 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr9_-_71896047 0.190 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr6_+_83034173 0.186 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr10_+_80142295 0.168 ENSMUST00000003156.8
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr7_+_101394361 0.166 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr1_+_177445660 0.161 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr2_+_69670100 0.157 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr5_-_28210168 0.154 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr10_+_80142358 0.151 ENSMUST00000105366.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr11_+_100320596 0.150 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr6_-_3494587 0.146 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr5_+_123076275 0.139 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr8_+_94838321 0.134 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr9_-_88719798 0.134 ENSMUST00000113110.3
Gm2382
predicted gene 2382
chr11_+_49247462 0.124 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr2_+_25403128 0.123 ENSMUST00000154809.1
ENSMUST00000055921.7
ENSMUST00000141567.1
Npdc1


neural proliferation, differentiation and control 1


chr4_-_141598206 0.118 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr13_+_49544443 0.116 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr2_-_39065438 0.109 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr2_-_39065505 0.108 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr10_-_25200110 0.100 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr2_+_21367532 0.098 ENSMUST00000055946.7
Gpr158
G protein-coupled receptor 158
chr15_+_82256023 0.094 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr2_+_164833781 0.092 ENSMUST00000143780.1
Ctsa
cathepsin A
chr1_+_129273344 0.082 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr16_+_16213318 0.082 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr4_+_127172866 0.082 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_+_73160403 0.079 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr2_+_164833841 0.078 ENSMUST00000152721.1
Ctsa
cathepsin A
chr7_+_127904079 0.075 ENSMUST00000071056.7
Bckdk
branched chain ketoacid dehydrogenase kinase
chr9_+_78175898 0.070 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr18_+_55057557 0.070 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr15_+_78913916 0.069 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_-_121807024 0.069 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr10_-_70655934 0.067 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr4_+_80910646 0.066 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr6_+_112273758 0.058 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chrX_+_56786527 0.056 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr9_-_26999491 0.055 ENSMUST00000060513.7
ENSMUST00000120367.1
Acad8

acyl-Coenzyme A dehydrogenase family, member 8

chr2_-_52558539 0.052 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr11_-_69920581 0.052 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr19_-_53371766 0.052 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr4_-_25281801 0.052 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr10_+_53596936 0.048 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr5_+_3343893 0.047 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr17_-_47016956 0.045 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chr17_+_82539258 0.045 ENSMUST00000097278.3
Gm6594
predicted pseudogene 6594
chr16_-_17722879 0.043 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr18_+_74216118 0.041 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr7_-_126704816 0.040 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr6_+_147032528 0.039 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr2_-_29253001 0.037 ENSMUST00000071201.4
Ntng2
netrin G2
chr11_-_76577701 0.033 ENSMUST00000176179.1
Abr
active BCR-related gene
chr2_+_127587214 0.032 ENSMUST00000028852.6
Mrps5
mitochondrial ribosomal protein S5
chr15_+_84669565 0.031 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr5_-_24447587 0.028 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr11_+_31872100 0.025 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr9_+_26999668 0.020 ENSMUST00000039161.8
Thyn1
thymocyte nuclear protein 1
chr16_-_57292845 0.018 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
Tmem30c


transmembrane protein 30C


chr8_-_106337987 0.016 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr11_-_69602741 0.012 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_-_141437587 0.011 ENSMUST00000172654.1
ENSMUST00000106006.1
Slc25a22

solute carrier family 25 (mitochondrial carrier, glutamate), member 22

chr19_+_7268296 0.008 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr7_-_126704522 0.005 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr11_-_97782409 0.004 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr6_-_83033422 0.004 ENSMUST00000089651.5
Dok1
docking protein 1
chr11_-_98329641 0.003 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr7_-_141437829 0.002 ENSMUST00000019226.7
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr9_+_72985568 0.000 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 1.2 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.3 0.8 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 2.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.2 GO:1900020 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)