Motif ID: Atoh1_Bhlhe23

Z-value: 0.583

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776900_1807769000.451.0e-01Click!


Activity profile for motif Atoh1_Bhlhe23.

activity profile for motif Atoh1_Bhlhe23


Sorted Z-values histogram for motif Atoh1_Bhlhe23

Sorted Z-values for motif Atoh1_Bhlhe23



Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Showing 1 to 20 of 114 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_79456750 2.178 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr3_+_118430299 1.600 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr1_+_42697146 1.214 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr5_+_124194894 1.012 ENSMUST00000159053.1
ENSMUST00000162577.1
 Gm16338

predicted gene 16338

chr15_-_91191733 0.972 ENSMUST00000069511.6
 Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr10_+_70204675 0.875 ENSMUST00000020090.1
 2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr1_+_150392794 0.826 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr3_-_59220150 0.724 ENSMUST00000170388.1
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_+_62046462 0.721 ENSMUST00000102735.3
 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr16_+_43235856 0.694 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chrX_+_56454871 0.693 ENSMUST00000039374.2
ENSMUST00000101553.2
 Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_-_92164666 0.693 ENSMUST00000183123.1
ENSMUST00000182033.1
 Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr2_+_62046580 0.687 ENSMUST00000054484.8
 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_62046623 0.667 ENSMUST00000112480.2
 Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr4_+_11579647 0.664 ENSMUST00000180239.1
 Fsbp
fibrinogen silencer binding protein
chr1_+_167618246 0.597 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma
chr1_+_177444653 0.586 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr4_-_110292719 0.554 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_-_97747399 0.500 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_111864869 0.468 ENSMUST00000035462.5
 Dsel
dermatan sulfate epimerase-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 2.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 1.2 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.1 1.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 0.8 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.2 GO:1900020 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.4 2.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0070888 E-box binding(GO:0070888)
0.1 2.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)