Motif ID: Bbx

Z-value: 0.384


Transcription factors associated with Bbx:

Gene SymbolEntrez IDGene Name
Bbx ENSMUSG00000022641.9 Bbx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50330987_50331017-0.421.4e-01Click!


Activity profile for motif Bbx.

activity profile for motif Bbx


Sorted Z-values histogram for motif Bbx

Sorted Z-values for motif Bbx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bbx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_49608030 1.326 ENSMUST00000021822.5
Ogn
osteoglycin
chr6_+_124304646 0.995 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr8_+_70616816 0.710 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr18_+_37421418 0.662 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr7_+_51880312 0.596 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr17_+_57358682 0.517 ENSMUST00000086763.5
ENSMUST00000004850.7
Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr7_-_127708886 0.481 ENSMUST00000061468.8
Bcl7c
B cell CLL/lymphoma 7C
chr5_-_108675569 0.290 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr7_-_127708738 0.259 ENSMUST00000106282.1
Bcl7c
B cell CLL/lymphoma 7C
chr12_-_86079019 0.256 ENSMUST00000003687.6
Tgfb3
transforming growth factor, beta 3
chr3_+_16183177 0.222 ENSMUST00000108345.2
ENSMUST00000108346.2
Ythdf3

YTH domain family 3

chr1_-_163725123 0.203 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr1_+_180111339 0.197 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr15_+_21111452 0.168 ENSMUST00000075132.6
Cdh12
cadherin 12
chr17_+_40811089 0.162 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr2_-_155592567 0.149 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
Gss


glutathione synthetase


chr7_+_127800604 0.127 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr8_-_41054771 0.117 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr10_+_86021961 0.092 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chrX_+_140367494 0.086 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr16_+_20693263 0.083 ENSMUST00000149543.1
ENSMUST00000118919.1
Fam131a

family with sequence similarity 131, member A

chr15_-_50882806 0.061 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr13_-_91807658 0.059 ENSMUST00000022121.6
Zcchc9
zinc finger, CCHC domain containing 9
chrX_-_150814265 0.025 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr11_+_105146893 0.015 ENSMUST00000100338.1
Gm10842
predicted gene 10842
chr5_-_146585239 0.012 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1 1.0 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.3 GO:0008083 growth factor activity(GO:0008083)