Motif ID: Bcl6
Z-value: 0.822
Transcription factors associated with Bcl6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl6 | ENSMUSG00000022508.5 | Bcl6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bcl6 | mm10_v2_chr16_-_23988852_23988852 | 0.08 | 8.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.4 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.3 | 1.4 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.3 | 1.1 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.2 | 2.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.2 | 0.6 | GO:0002034 | ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) establishment of blood-nerve barrier(GO:0008065) regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) regulation of membrane hyperpolarization(GO:1902630) |
| 0.2 | 1.4 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.2 | 0.5 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.2 | 1.2 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.2 | 0.7 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.2 | 0.5 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.2 | 0.8 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 0.8 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.9 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 0.7 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.1 | 0.3 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 0.1 | 0.7 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.1 | 0.2 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 0.1 | 0.3 | GO:2000587 | regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.1 | 0.3 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 0.2 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 0.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.6 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 1.2 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 0.6 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421) |
| 0.1 | 0.2 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.1 | 0.5 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.0 | 0.2 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.0 | 0.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.4 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.0 | 0.2 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.0 | 0.3 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.0 | 0.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.0 | 0.1 | GO:0086017 | renin secretion into blood stream(GO:0002001) septum primum development(GO:0003284) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) regulation of renin secretion into blood stream(GO:1900133) |
| 0.0 | 0.2 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.0 | 0.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.0 | 0.3 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.0 | 0.2 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.0 | 0.1 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
| 0.0 | 0.2 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.8 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.0 | 0.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.4 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.2 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.0 | 0.2 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.0 | 0.5 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
| 0.0 | 0.2 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
| 0.0 | 0.2 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.0 | 0.4 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.1 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.0 | 0.2 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.0 | 0.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.0 | 0.4 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.2 | GO:0070633 | transepithelial transport(GO:0070633) |
| 0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) membrane fission(GO:0090148) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.0 | 0.1 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.0 | 0.4 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.0 | 0.1 | GO:0048819 | regulation of hair follicle maturation(GO:0048819) regulation of catagen(GO:0051794) |
| 0.0 | 0.1 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.0 | 0.5 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.2 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 0.1 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 0.1 | GO:0048875 | calcium-mediated signaling using intracellular calcium source(GO:0035584) chemical homeostasis within a tissue(GO:0048875) |
| 0.0 | 0.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.0 | 0.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 0.0 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.0 | 0.3 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.2 | 0.6 | GO:0044299 | C-fiber(GO:0044299) |
| 0.2 | 1.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 0.5 | GO:0005940 | septin ring(GO:0005940) |
| 0.1 | 0.8 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.7 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 1.7 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.5 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 0.3 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.1 | 0.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.2 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.1 | 0.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.1 | 0.8 | GO:0044292 | dendrite terminus(GO:0044292) |
| 0.1 | 0.2 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.0 | 0.7 | GO:0043205 | fibril(GO:0043205) |
| 0.0 | 0.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.3 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.7 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.1 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.3 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 1.4 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.2 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.5 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.3 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.2 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.3 | 1.2 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.3 | 1.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.2 | 1.4 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.2 | 0.6 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 0.7 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.1 | 0.9 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.3 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.1 | 1.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.7 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.1 | 0.8 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.9 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 0.1 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.3 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.6 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 0.2 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.1 | 0.2 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.1 | 0.4 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 0.6 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.8 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.8 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 0.3 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.0 | 0.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.3 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.1 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.2 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 1.2 | GO:0019842 | vitamin binding(GO:0019842) |
| 0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 0.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.1 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
