Motif ID: Bcl6

Z-value: 0.822


Transcription factors associated with Bcl6:

Gene SymbolEntrez IDGene Name
Bcl6 ENSMUSG00000022508.5 Bcl6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6mm10_v2_chr16_-_23988852_239888520.088.0e-01Click!


Activity profile for motif Bcl6.

activity profile for motif Bcl6


Sorted Z-values histogram for motif Bcl6

Sorted Z-values for motif Bcl6



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_58801944 1.500 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr10_+_86300372 1.395 ENSMUST00000020234.7
Timp3
tissue inhibitor of metalloproteinase 3
chr4_-_64046925 1.393 ENSMUST00000107377.3
Tnc
tenascin C
chr4_+_15881255 1.228 ENSMUST00000029876.1
Calb1
calbindin 1
chr18_-_36726730 1.143 ENSMUST00000061829.6
Cd14
CD14 antigen
chr4_+_144892813 1.079 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr19_+_34217588 0.939 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr7_+_129257027 0.870 ENSMUST00000094018.4
Ppapdc1a
phosphatidic acid phosphatase type 2 domain containing 1A
chr4_+_144893077 0.858 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr9_+_20868628 0.851 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr4_+_144893127 0.802 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_175491130 0.777 ENSMUST00000027812.5
Rgs7
regulator of G protein signaling 7
chr10_+_22158566 0.764 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr9_-_39604124 0.730 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr8_+_94532990 0.729 ENSMUST00000048653.2
ENSMUST00000109537.1
Cpne2

copine II

chr8_+_70616816 0.704 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr4_+_120666562 0.695 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr16_+_62854299 0.659 ENSMUST00000023629.8
Pros1
protein S (alpha)
chr4_+_152274191 0.656 ENSMUST00000105650.1
ENSMUST00000105651.1
Gpr153

G protein-coupled receptor 153

chr9_+_123150941 0.651 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.2 GO:0007614 short-term memory(GO:0007614)
0.3 1.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.0 0.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 0.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.0 0.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.2 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.7 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.6 GO:0002034 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) establishment of blood-nerve barrier(GO:0008065) regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) regulation of membrane hyperpolarization(GO:1902630)
0.1 0.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
0.2 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:0043195 terminal bouton(GO:0043195)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.8 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.7 GO:0001652 granular component(GO:0001652)
0.0 0.7 GO:0043205 fibril(GO:0043205)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.6 GO:0044299 C-fiber(GO:0044299)
0.2 0.5 GO:0005940 septin ring(GO:0005940)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.4 GO:0045545 syndecan binding(GO:0045545)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 1.2 GO:0019842 vitamin binding(GO:0019842)
0.3 1.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)