Motif ID: Bcl6b

Z-value: 0.667


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.107.3e-01Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_94404258 1.585 ENSMUST00000035342.4
ENSMUST00000155907.1
 Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr15_-_93519499 1.293 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chr9_-_90255927 1.065 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr3_+_67892189 0.978 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr19_-_5797410 0.954 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_34263179 0.874 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr16_-_34262830 0.820 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr3_+_55242526 0.807 ENSMUST00000054237.7
ENSMUST00000167204.1
 Dclk1

doublecortin-like kinase 1

chr16_-_34262945 0.804 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr2_+_119594288 0.705 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr5_-_150665315 0.621 ENSMUST00000141857.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr10_-_95416850 0.614 ENSMUST00000020215.9
 Socs2
suppressor of cytokine signaling 2
chr11_+_93098404 0.595 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
 Car10



carbonic anhydrase 10



chr10_-_86705485 0.592 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr9_+_40269430 0.548 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chrX_-_43274786 0.539 ENSMUST00000016294.7
 Tenm1
teneurin transmembrane protein 1
chr16_-_74411776 0.509 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411292 0.507 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr10_-_95417099 0.477 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr9_+_86743641 0.461 ENSMUST00000179574.1
 Prss35
protease, serine, 35

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.6 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.4 1.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 1.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 1.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.3 0.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)