Motif ID: Bcl6b

Z-value: 0.667


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.107.3e-01Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_94404258 1.585 ENSMUST00000035342.4
ENSMUST00000155907.1
 Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr15_-_93519499 1.293 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chr9_-_90255927 1.065 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr3_+_67892189 0.978 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr19_-_5797410 0.954 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_34263179 0.874 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr16_-_34262830 0.820 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr3_+_55242526 0.807 ENSMUST00000054237.7
ENSMUST00000167204.1
 Dclk1

doublecortin-like kinase 1

chr16_-_34262945 0.804 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr2_+_119594288 0.705 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr5_-_150665315 0.621 ENSMUST00000141857.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr10_-_95416850 0.614 ENSMUST00000020215.9
 Socs2
suppressor of cytokine signaling 2
chr11_+_93098404 0.595 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
 Car10



carbonic anhydrase 10



chr10_-_86705485 0.592 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr9_+_40269430 0.548 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chrX_-_43274786 0.539 ENSMUST00000016294.7
 Tenm1
teneurin transmembrane protein 1
chr16_-_74411776 0.509 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411292 0.507 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr10_-_95417099 0.477 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr9_+_86743641 0.461 ENSMUST00000179574.1
 Prss35
protease, serine, 35
chrX_+_153359613 0.412 ENSMUST00000039545.4
 Klf8
Kruppel-like factor 8
chr1_+_191717834 0.399 ENSMUST00000110855.1
ENSMUST00000133076.1
 Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr8_+_25601591 0.396 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr3_-_88372740 0.389 ENSMUST00000107543.1
ENSMUST00000107542.1
 Bglap3

bone gamma-carboxyglutamate protein 3

chr18_-_37644185 0.384 ENSMUST00000066272.4
 Taf7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_+_86743616 0.368 ENSMUST00000036426.6
 Prss35
protease, serine, 35
chr18_+_42275353 0.340 ENSMUST00000046972.7
ENSMUST00000091920.5
 Rbm27

RNA binding motif protein 27

chr2_-_180824596 0.330 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr13_-_98815408 0.327 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr5_-_150665560 0.320 ENSMUST00000118316.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chrX_+_151344171 0.299 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr7_+_43579577 0.298 ENSMUST00000058104.7
 Zfp719
zinc finger protein 719
chr12_-_40134175 0.296 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr4_+_3574872 0.289 ENSMUST00000052712.5
 Tgs1
trimethylguanosine synthase homolog (S. cerevisiae)
chr6_+_149309391 0.286 ENSMUST00000130664.1
ENSMUST00000046689.6
 2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr12_-_98577940 0.285 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr1_-_37536232 0.284 ENSMUST00000042161.8
 Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chrX_+_152233228 0.272 ENSMUST00000112588.2
ENSMUST00000082177.6
 Kdm5c

lysine (K)-specific demethylase 5C

chr11_+_95712673 0.264 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr11_-_102819663 0.263 ENSMUST00000092567.4
 Gjc1
gap junction protein, gamma 1
chr15_-_97020322 0.242 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr2_-_65567465 0.228 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr15_-_103215285 0.219 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr6_+_149309444 0.219 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr13_-_76018524 0.213 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
 Rfesd


Rieske (Fe-S) domain containing


chr2_-_65567505 0.197 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_+_95588960 0.190 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr10_+_69213084 0.186 ENSMUST00000163497.1
ENSMUST00000164212.1
ENSMUST00000067908.7
 Rhobtb1


Rho-related BTB domain containing 1


chrX_+_74429671 0.184 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
 Ikbkg


inhibitor of kappaB kinase gamma


chr2_-_77946331 0.159 ENSMUST00000111821.2
ENSMUST00000111818.1
 Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr2_-_77946375 0.154 ENSMUST00000065889.3
 Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_139454747 0.151 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr11_+_70764209 0.132 ENSMUST00000060444.5
 Zfp3
zinc finger protein 3
chr4_+_155562348 0.131 ENSMUST00000030939.7
 Nadk
NAD kinase
chr11_+_58432559 0.127 ENSMUST00000108825.1
 Gm12253
predicted gene 12253
chr8_+_13907748 0.119 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chr7_+_48789003 0.119 ENSMUST00000118927.1
ENSMUST00000125280.1
 Zdhhc13

zinc finger, DHHC domain containing 13

chr9_-_112232449 0.114 ENSMUST00000035085.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr3_+_95588928 0.108 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like


chr6_-_128355826 0.101 ENSMUST00000001562.6
 Tulp3
tubby-like protein 3
chr11_-_102819114 0.090 ENSMUST00000068933.5
 Gjc1
gap junction protein, gamma 1
chr2_-_73486456 0.084 ENSMUST00000141264.1
 Wipf1
WAS/WASL interacting protein family, member 1
chr18_+_37320374 0.082 ENSMUST00000078271.2
 Pcdhb5
protocadherin beta 5
chr1_-_136230289 0.082 ENSMUST00000150163.1
ENSMUST00000144464.1
 5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr15_+_25752860 0.076 ENSMUST00000022882.5
ENSMUST00000135173.1
 Myo10

myosin X

chr9_+_56994932 0.070 ENSMUST00000034832.6
 Ptpn9
protein tyrosine phosphatase, non-receptor type 9
chr3_+_95588990 0.069 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr6_+_106769120 0.069 ENSMUST00000113247.1
ENSMUST00000113249.1
ENSMUST00000057578.9
ENSMUST00000113248.1
 Trnt1



tRNA nucleotidyl transferase, CCA-adding, 1



chr2_+_131133497 0.063 ENSMUST00000110225.1
 Gm11037
predicted gene 11037
chr19_-_10555724 0.038 ENSMUST00000145210.1
ENSMUST00000123788.1
ENSMUST00000059582.2
ENSMUST00000154383.1
 Tmem216



transmembrane protein 216



chr7_-_16221993 0.026 ENSMUST00000118795.1
ENSMUST00000119102.1
ENSMUST00000094816.2
ENSMUST00000163968.1
ENSMUST00000121123.1
 Dhx34




DEAH (Asp-Glu-Ala-His) box polypeptide 34




chr4_+_149485260 0.023 ENSMUST00000030842.7
 Lzic
leucine zipper and CTNNBIP1 domain containing
chr2_-_155729359 0.023 ENSMUST00000040833.4
 Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr3_-_96240317 0.020 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr8_-_105568298 0.005 ENSMUST00000005849.5
 Agrp
agouti related protein
chr18_-_78123324 0.004 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 0.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.3 2.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.6 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.1 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)