Motif ID: Cbfb

Z-value: 0.346


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_105170686-0.126.7e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_101729690 0.697 ENSMUST00000066461.3
 Gm9922
predicted gene 9922
chr2_+_172393794 0.489 ENSMUST00000099061.2
ENSMUST00000103073.2
 Cass4

Cas scaffolding protein family member 4

chr4_-_6990774 0.470 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr12_+_95692212 0.450 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr2_+_72297895 0.334 ENSMUST00000144111.1
 Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr8_+_3353415 0.233 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr14_+_101729907 0.227 ENSMUST00000100337.3
 Lmo7
LIM domain only 7
chr15_-_66801577 0.211 ENSMUST00000168589.1
 Sla
src-like adaptor
chr8_+_90828820 0.200 ENSMUST00000109614.2
ENSMUST00000048665.6
 Chd9

chromodomain helicase DNA binding protein 9

chr10_+_69925954 0.190 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
 Ank3


ankyrin 3, epithelial


chr2_+_35132194 0.174 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
 Cep110


centrosomal protein 110


chr2_+_164948219 0.148 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr4_+_10874498 0.114 ENSMUST00000080517.7
ENSMUST00000101504.2
 2610301B20Rik

RIKEN cDNA 2610301B20 gene

chr9_-_48480540 0.112 ENSMUST00000034524.3
 Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr6_+_136954521 0.096 ENSMUST00000137768.1
 Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr1_+_151755339 0.096 ENSMUST00000059498.5
 Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr9_-_66126559 0.089 ENSMUST00000137542.1
 Snx1
sorting nexin 1
chr11_+_20631956 0.085 ENSMUST00000109586.2
 Sertad2
SERTA domain containing 2
chr11_-_74724670 0.080 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chrX_+_99136119 0.069 ENSMUST00000052839.6
 Efnb1
ephrin B1
chr4_+_83417715 0.068 ENSMUST00000030206.3
ENSMUST00000071544.4
 Snapc3

small nuclear RNA activating complex, polypeptide 3

chr9_+_66126611 0.064 ENSMUST00000034945.5
 Fam96a
family with sequence similarity 96, member A
chr8_+_27260327 0.058 ENSMUST00000033880.5
 Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr5_+_24364804 0.049 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr7_-_46795881 0.049 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr14_-_64949838 0.044 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
 Hmbox1





homeobox containing 1





chr1_-_63176653 0.032 ENSMUST00000027111.8
ENSMUST00000168099.2
 Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr1_-_174921813 0.032 ENSMUST00000055294.3
 Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr3_+_121291725 0.023 ENSMUST00000039442.7
 Alg14
asparagine-linked glycosylation 14
chr19_+_5050807 0.014 ENSMUST00000025818.6
 Rin1
Ras and Rab interactor 1
chr4_-_117891994 0.002 ENSMUST00000030265.3
 Dph2
DPH2 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)