Motif ID: Cebpb

Z-value: 1.446


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.612.1e-02Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

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Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_57358682 4.726 ENSMUST00000086763.5
ENSMUST00000004850.7
 Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr14_+_51091077 4.725 ENSMUST00000022428.5
ENSMUST00000171688.1
 Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr6_+_17463749 4.649 ENSMUST00000115443.1
 Met
met proto-oncogene
chr2_-_25469742 4.611 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr3_+_66219909 4.590 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr17_+_48346401 4.501 ENSMUST00000024791.8
 Trem2
triggering receptor expressed on myeloid cells 2
chr2_-_25470031 4.466 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr17_+_48346465 4.265 ENSMUST00000113237.3
 Trem2
triggering receptor expressed on myeloid cells 2
chr19_+_12460749 3.933 ENSMUST00000081035.7
 Mpeg1
macrophage expressed gene 1
chr11_-_83649349 3.747 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr8_+_75093591 3.673 ENSMUST00000005548.6
 Hmox1
heme oxygenase (decycling) 1
chr16_+_42907563 3.251 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr5_+_75152274 3.051 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_66386292 2.950 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr14_+_99298652 2.838 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr3_-_116968969 2.628 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr3_+_109573907 2.375 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr1_+_169655493 2.328 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr18_-_38601268 2.270 ENSMUST00000025295.6
 Spry4
sprouty homolog 4 (Drosophila)
chr11_-_78984831 1.837 ENSMUST00000073001.4
ENSMUST00000108269.3
 Lgals9

lectin, galactose binding, soluble 9


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 9.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
2.9 8.8 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
1.6 4.7 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
1.5 4.6 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.5 4.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.2 3.7 GO:1904706 response to cisplatin(GO:0072718) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 3.7 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.0 3.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 3.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 2.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4 2.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 2.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 2.3 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 2.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.2 2.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 1.8 GO:2000562 positive regulation of defense response to bacterium(GO:1900426) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.4 1.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 1.7 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 1.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
1.6 4.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 4.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 3.7 GO:0005901 caveola(GO:0005901)
0.0 3.1 GO:0005902 microvillus(GO:0005902)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.9 GO:0043203 axon hillock(GO:0043203)
0.0 2.7 GO:0005938 cell cortex(GO:0005938)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.3 1.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.3 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 11.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.3 9.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 4.7 GO:0005507 copper ion binding(GO:0005507)
1.2 4.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.9 4.6 GO:0001849 complement component C1q binding(GO:0001849)
0.9 3.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 3.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 3.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 2.3 GO:0016936 galactoside binding(GO:0016936)
0.1 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.7 2.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 1.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.4 1.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 1.3 GO:0042296 ISG15 transferase activity(GO:0042296)