Motif ID: Chd1_Pml

Z-value: 4.501

Transcription factors associated with Chd1_Pml:

Gene SymbolEntrez IDGene Name
Chd1 ENSMUSG00000023852.7 Chd1
Pml ENSMUSG00000036986.10 Pml

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Chd1mm10_v2_chr17_+_15704963_157049940.488.2e-02Click!
Pmlmm10_v2_chr9_-_58249660_58249672-0.322.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Chd1_Pml

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_123982799 15.296 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr7_+_36698002 15.100 ENSMUST00000021641.6
Tshz3
teashirt zinc finger family member 3
chr14_-_39472825 11.330 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr4_+_32238950 11.067 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr4_+_62965560 9.663 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr18_+_59175333 9.561 ENSMUST00000080721.4
Chsy3
chondroitin sulfate synthase 3
chr4_+_125490688 9.324 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr6_-_39725193 9.269 ENSMUST00000101497.3
Braf
Braf transforming gene
chr1_+_167001457 9.186 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr11_-_33147400 9.181 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr4_+_32238713 9.115 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr4_-_123664725 9.048 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr14_-_102982630 8.688 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr6_-_99520949 8.644 ENSMUST00000176565.1
Foxp1
forkhead box P1
chr5_-_25498748 8.613 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr6_-_38875923 8.055 ENSMUST00000162359.1
Hipk2
homeodomain interacting protein kinase 2
chr7_+_117380937 7.951 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr12_+_44328882 7.950 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chrX_+_69360294 7.786 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr6_-_114042020 7.766 ENSMUST00000101045.3
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,020 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 36.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
2.8 22.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.3 18.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
5.8 17.5 GO:0050975 sensory perception of touch(GO:0050975)
2.1 16.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
4.1 16.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.5 15.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.0 15.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.5 15.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
1.1 13.7 GO:0006857 oligopeptide transport(GO:0006857)
1.7 13.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.5 13.3 GO:1901660 calcium ion export(GO:1901660)
0.3 12.3 GO:0061512 protein localization to cilium(GO:0061512)
0.1 11.9 GO:0016579 protein deubiquitination(GO:0016579)
1.5 11.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 11.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
2.8 11.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.9 11.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
3.6 10.8 GO:0060596 mammary placode formation(GO:0060596)
1.2 10.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 379 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 103.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.7 44.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 29.9 GO:0016605 PML body(GO:0016605)
0.4 27.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 26.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 22.7 GO:0005794 Golgi apparatus(GO:0005794)
0.7 22.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 21.2 GO:0030427 site of polarized growth(GO:0030427)
1.1 18.8 GO:0097470 ribbon synapse(GO:0097470)
0.5 18.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 18.0 GO:0043197 dendritic spine(GO:0043197)
0.6 17.9 GO:0032839 dendrite cytoplasm(GO:0032839)
5.5 16.6 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.5 15.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.3 15.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 14.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.5 14.0 GO:0043194 axon initial segment(GO:0043194)
1.1 13.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 13.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 13.3 GO:0030118 clathrin coat(GO:0030118)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 535 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 88.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 37.7 GO:0017137 Rab GTPase binding(GO:0017137)
1.2 33.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 32.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.2 28.0 GO:0008017 microtubule binding(GO:0008017)
0.1 27.7 GO:0005096 GTPase activator activity(GO:0005096)
2.8 24.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.0 22.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.8 22.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.5 20.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
2.5 19.9 GO:0046790 virion binding(GO:0046790)
1.0 19.1 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.8 18.7 GO:0070064 proline-rich region binding(GO:0070064)
0.3 18.0 GO:0048365 Rac GTPase binding(GO:0048365)
1.1 17.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 17.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 16.4 GO:0030507 spectrin binding(GO:0030507)
0.6 16.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 15.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 15.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)