Motif ID: Creb1

Z-value: 1.116


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.039.1e-01Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_102982630 2.278 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr12_-_4907705 1.465 ENSMUST00000020962.5
 Ubxn2a
UBX domain protein 2A
chr13_-_29984219 1.431 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr12_-_4907229 1.240 ENSMUST00000142867.1
 Ubxn2a
UBX domain protein 2A
chr7_-_126082406 1.069 ENSMUST00000073935.5
 Gsg1l
GSG1-like
chr7_-_47008397 1.055 ENSMUST00000061639.7
 Spty2d1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr13_-_46727932 0.887 ENSMUST00000021803.9
 Nup153
nucleoporin 153
chr8_+_117157972 0.880 ENSMUST00000064488.4
ENSMUST00000162997.1
 Gan

giant axonal neuropathy

chr2_-_162661075 0.876 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T



chr4_+_138454305 0.875 ENSMUST00000050918.3
 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr12_+_86678685 0.796 ENSMUST00000021681.3
 Vash1
vasohibin 1
chr4_-_58553553 0.796 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr2_+_71786923 0.776 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr4_-_58553311 0.773 ENSMUST00000107571.1
ENSMUST00000055018.4
 Lpar1

lysophosphatidic acid receptor 1

chr3_+_108284089 0.768 ENSMUST00000102632.4
 Sort1
sortilin 1
chr5_+_67260794 0.741 ENSMUST00000161369.1
 Tmem33
transmembrane protein 33
chr10_+_62920648 0.737 ENSMUST00000144459.1
 Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr14_+_33923582 0.736 ENSMUST00000168727.1
 Gdf10
growth differentiation factor 10
chr17_+_29660710 0.722 ENSMUST00000130423.1
 Cmtr1
cap methyltransferase 1
chr7_-_137314394 0.685 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 2.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.5 1.4 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.4 1.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 1.3 GO:0000012 single strand break repair(GO:0000012)
0.1 1.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.3 GO:0051646 mitochondrion localization(GO:0051646)
0.4 1.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.4 1.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 1.2 GO:0060976 coronary vasculature development(GO:0060976)
0.5 1.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 1.1 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.2 0.9 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.9 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 0.8 GO:1903722 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) regulation of centriole elongation(GO:1903722)
0.2 0.8 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.8 GO:0035878 nail development(GO:0035878)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.3 1.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.2 0.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.7 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 2.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 1.3 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 0.9 GO:0043495 protein anchor(GO:0043495)
0.2 0.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097)
0.0 0.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.1 0.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.6 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)