Motif ID: Creb3

Z-value: 0.521


Transcription factors associated with Creb3:

Gene SymbolEntrez IDGene Name
Creb3 ENSMUSG00000028466.9 Creb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3mm10_v2_chr4_+_43562672_435629470.117.2e-01Click!


Activity profile for motif Creb3.

activity profile for motif Creb3


Sorted Z-values histogram for motif Creb3

Sorted Z-values for motif Creb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_37185897 0.753 ENSMUST00000094840.3
 Gm1043
predicted gene 1043
chr2_-_172043466 0.634 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr3_+_123267445 0.574 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr5_-_148995147 0.523 ENSMUST00000147473.1
 Katnal1
katanin p60 subunit A-like 1
chr4_+_57568144 0.483 ENSMUST00000102904.3
 Palm2
paralemmin 2
chr11_-_108343917 0.480 ENSMUST00000059595.4
 Prkca
protein kinase C, alpha
chr18_+_57354733 0.474 ENSMUST00000025490.8
 Prrc1
proline-rich coiled-coil 1
chr1_+_119526125 0.457 ENSMUST00000183952.1
 TMEM185B
Transmembrane protein 185B
chr7_-_143460989 0.456 ENSMUST00000167912.1
ENSMUST00000037287.6
 Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr6_+_77242644 0.450 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr9_+_44379536 0.443 ENSMUST00000161318.1
ENSMUST00000160902.1
 Hyou1

hypoxia up-regulated 1

chr6_+_77242715 0.441 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr19_-_4989964 0.433 ENSMUST00000056129.7
 Npas4
neuronal PAS domain protein 4
chr1_-_93445642 0.431 ENSMUST00000042498.7
 Hdlbp
high density lipoprotein (HDL) binding protein
chr12_+_4082596 0.428 ENSMUST00000049584.5
 Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr8_-_34146974 0.423 ENSMUST00000033910.8
 Leprotl1
leptin receptor overlapping transcript-like 1
chr9_+_44379490 0.416 ENSMUST00000066601.6
 Hyou1
hypoxia up-regulated 1
chr17_-_84466186 0.385 ENSMUST00000047524.8
 Thada
thyroid adenoma associated
chr6_+_88084473 0.364 ENSMUST00000032143.6
 Rpn1
ribophorin I
chr11_-_113751813 0.363 ENSMUST00000053536.4
 Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.9 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3 0.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0060065 uterus development(GO:0060065)
0.0 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.4 GO:0018158 protein oxidation(GO:0018158)
0.1 0.4 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 0.3 GO:0071873 response to norepinephrine(GO:0071873)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0097413 Lewy body(GO:0097413)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)