Motif ID: Creb3l2

Z-value: 0.511


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_37442154-0.244.0e-01Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_123267445 1.702 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr10_+_13090788 0.927 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
 Plagl1


pleiomorphic adenoma gene-like 1


chr2_+_129198757 0.780 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr3_+_153973436 0.685 ENSMUST00000089948.5
 Slc44a5
solute carrier family 44, member 5
chr9_+_89909775 0.675 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chrX_+_8271133 0.563 ENSMUST00000127103.1
ENSMUST00000115591.1
 Slc38a5

solute carrier family 38, member 5

chr3_+_104638658 0.507 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr6_+_13871517 0.423 ENSMUST00000181090.1
ENSMUST00000181225.1
 1110019D14Rik

RIKEN cDNA 1110019D14 gene

chr2_+_68861564 0.394 ENSMUST00000176018.1
 Cers6
ceramide synthase 6
chr15_+_34495302 0.386 ENSMUST00000052290.7
ENSMUST00000079028.5
 Pop1

processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)

chr2_+_84840612 0.335 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr15_+_79516396 0.328 ENSMUST00000010974.7
 Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr12_+_112588753 0.317 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr13_-_24206281 0.306 ENSMUST00000123076.1
 Lrrc16a
leucine rich repeat containing 16A
chrX_+_163908982 0.299 ENSMUST00000069041.8
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr13_+_73330982 0.298 ENSMUST00000022098.8
 Mrpl36
mitochondrial ribosomal protein L36
chr13_-_90089513 0.293 ENSMUST00000160232.1
 Xrcc4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr17_-_24163668 0.287 ENSMUST00000040735.5
 Amdhd2
amidohydrolase domain containing 2
chr4_+_128654686 0.266 ENSMUST00000030588.6
ENSMUST00000136377.1
 Phc2

polyhomeotic-like 2 (Drosophila)

chr2_+_144368961 0.265 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
 Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.8 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.6 GO:0015816 glycine transport(GO:0015816)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.3 GO:2000813 actin filament uncapping(GO:0051695) negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.3 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.3 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)