Motif ID: Crx_Gsc

Z-value: 0.480

Transcription factors associated with Crx_Gsc:

Gene SymbolEntrez IDGene Name
Crx ENSMUSG00000041578.9 Crx
Gsc ENSMUSG00000021095.4 Gsc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Crxmm10_v2_chr7_-_15879844_158799680.401.6e-01Click!


Activity profile for motif Crx_Gsc.

activity profile for motif Crx_Gsc


Sorted Z-values histogram for motif Crx_Gsc

Sorted Z-values for motif Crx_Gsc



Network of associatons between targets according to the STRING database.



First level regulatory network of Crx_Gsc

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_42706369 0.986 ENSMUST00000180131.1
 Gm17067
predicted gene 17067
chrY_+_1010543 0.971 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr1_-_52490736 0.519 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr1_+_178187721 0.512 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr1_-_154725920 0.490 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_109983006 0.448 ENSMUST00000145188.1
 Cdh7
cadherin 7, type 2
chr4_+_74013442 0.441 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr11_-_70459957 0.410 ENSMUST00000019064.2
 Cxcl16
chemokine (C-X-C motif) ligand 16
chr13_-_66227573 0.396 ENSMUST00000167981.2
 Gm10772
predicted gene 10772
chr11_+_70459940 0.388 ENSMUST00000147289.1
ENSMUST00000126105.1
 Zmynd15

zinc finger, MYND-type containing 15

chr5_+_77265454 0.363 ENSMUST00000080359.5
 Rest
RE1-silencing transcription factor
chr1_-_155417394 0.357 ENSMUST00000111775.1
ENSMUST00000111774.1
 Xpr1

xenotropic and polytropic retrovirus receptor 1

chr13_+_110395041 0.316 ENSMUST00000022212.7
 Plk2
polo-like kinase 2
chr7_-_134938264 0.289 ENSMUST00000171394.1
 Fam196a
family with sequence similarity 196, member A
chr5_-_74068361 0.282 ENSMUST00000119154.1
ENSMUST00000068058.7
 Usp46

ubiquitin specific peptidase 46

chr1_-_126738167 0.277 ENSMUST00000160693.1
 Nckap5
NCK-associated protein 5
chr16_+_23290464 0.273 ENSMUST00000115335.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr14_-_19977040 0.272 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr10_+_90576872 0.272 ENSMUST00000182550.1
ENSMUST00000099364.5
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr5_-_112589990 0.272 ENSMUST00000183186.1
ENSMUST00000182949.1
 1700034G24Rik

RIKEN cDNA 1700034G24 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.3 GO:1990743 protein sialylation(GO:1990743)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:1990035 calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.1 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)