Motif ID: Cux1
Z-value: 1.314
Transcription factors associated with Cux1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Cux1 | ENSMUSG00000029705.11 | Cux1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Cux1 | mm10_v2_chr5_-_136567242_136567287 | 0.87 | 6.4e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.9 | 8.7 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
1.3 | 4.0 | GO:2001139 | negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139) |
0.6 | 1.9 | GO:0050929 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
0.5 | 1.6 | GO:2001180 | negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180) |
0.4 | 1.5 | GO:1900272 | negative regulation of long-term synaptic potentiation(GO:1900272) |
0.4 | 1.1 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.4 | 1.4 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.3 | 1.0 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.3 | 1.4 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.3 | 1.0 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
0.3 | 1.3 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.3 | 0.9 | GO:0035622 | intrahepatic bile duct development(GO:0035622) |
0.3 | 0.8 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.3 | 1.3 | GO:0070295 | renal water absorption(GO:0070295) |
0.3 | 0.5 | GO:0010873 | positive regulation of cholesterol esterification(GO:0010873) |
0.2 | 0.9 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.2 | 2.3 | GO:0060346 | bone trabecula formation(GO:0060346) |
0.2 | 0.7 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
0.2 | 1.8 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.2 | 0.8 | GO:0006842 | tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) |
0.2 | 0.6 | GO:0015889 | cobalamin transport(GO:0015889) |
0.2 | 0.9 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.2 | 0.5 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.2 | 2.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.2 | 0.5 | GO:0046078 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) dUMP metabolic process(GO:0046078) |
0.2 | 3.0 | GO:0019835 | cytolysis(GO:0019835) |
0.1 | 0.4 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
0.1 | 1.1 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
0.1 | 1.3 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 0.4 | GO:0097114 | NMDA glutamate receptor clustering(GO:0097114) |
0.1 | 0.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 1.6 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.1 | 0.5 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
0.1 | 0.5 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
0.1 | 3.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.8 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
0.1 | 0.8 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.3 | GO:0030862 | regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
0.1 | 0.5 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.1 | 2.2 | GO:0007614 | short-term memory(GO:0007614) |
0.1 | 0.3 | GO:2000983 | regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984) |
0.1 | 0.3 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.1 | 0.3 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.1 | 0.5 | GO:0021508 | floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505) |
0.1 | 0.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 0.4 | GO:0007412 | axon target recognition(GO:0007412) |
0.1 | 2.3 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.1 | 0.3 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
0.1 | 0.5 | GO:0051541 | elastin metabolic process(GO:0051541) |
0.1 | 0.8 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
0.1 | 0.4 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.1 | 0.5 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.1 | 1.1 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
0.1 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.1 | 0.8 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.1 | 1.1 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.1 | 1.0 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 0.3 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.1 | 0.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.6 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.1 | 0.3 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.1 | 1.0 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.1 | 0.2 | GO:0021546 | rhombomere development(GO:0021546) |
0.1 | 0.4 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.1 | 0.5 | GO:0030578 | PML body organization(GO:0030578) |
0.1 | 0.5 | GO:0070813 | hydrogen sulfide metabolic process(GO:0070813) |
0.1 | 1.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.1 | 0.5 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.2 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
0.1 | 1.6 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
0.1 | 0.8 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.1 | 0.1 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
0.1 | 0.3 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.1 | 0.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 0.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.1 | 0.6 | GO:0015816 | glycine transport(GO:0015816) |
0.1 | 0.3 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.1 | 0.3 | GO:0034214 | protein hexamerization(GO:0034214) |
0.1 | 0.2 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.0 | 0.1 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.0 | 0.1 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.3 | GO:0002934 | desmosome organization(GO:0002934) |
0.0 | 0.2 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.0 | 0.1 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.0 | 0.2 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
0.0 | 1.0 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.0 | 0.4 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.0 | 0.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.0 | 0.2 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 0.6 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.6 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.0 | 0.3 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.0 | 0.2 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
0.0 | 0.4 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.1 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.0 | 1.3 | GO:0031114 | negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
0.0 | 0.1 | GO:0014028 | notochord formation(GO:0014028) |
0.0 | 0.4 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
0.0 | 0.1 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.0 | 0.4 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.0 | 0.5 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
0.0 | 0.2 | GO:0046909 | intermembrane transport(GO:0046909) |
0.0 | 0.3 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 0.6 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.1 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.0 | 0.4 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
0.0 | 0.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.0 | 0.1 | GO:0039530 | MDA-5 signaling pathway(GO:0039530) |
0.0 | 1.1 | GO:0022900 | electron transport chain(GO:0022900) |
0.0 | 2.9 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 0.5 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.2 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
0.0 | 0.1 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.0 | 0.1 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
0.0 | 0.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
0.0 | 0.4 | GO:0031670 | cellular response to nutrient(GO:0031670) |
0.0 | 0.1 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
0.0 | 0.1 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 1.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.1 | GO:0046208 | spermine catabolic process(GO:0046208) |
0.0 | 0.2 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.2 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.0 | 0.2 | GO:0015825 | L-serine transport(GO:0015825) |
0.0 | 0.3 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 1.1 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.0 | 0.0 | GO:0097461 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) |
0.0 | 0.1 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) positive regulation of superoxide anion generation(GO:0032930) negative regulation of vasodilation(GO:0045908) |
0.0 | 0.0 | GO:0000389 | generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389) |
0.0 | 0.3 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 0.1 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.0 | 0.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
0.0 | 0.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.2 | GO:0010388 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
0.0 | 0.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.2 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.0 | 0.9 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
0.0 | 0.2 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
0.0 | 0.0 | GO:2000015 | regulation of determination of dorsal identity(GO:2000015) |
0.0 | 0.6 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.0 | 0.3 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.5 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
0.0 | 0.0 | GO:0061724 | protein to membrane docking(GO:0022615) lipophagy(GO:0061724) |
0.0 | 0.2 | GO:0006825 | copper ion transport(GO:0006825) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 4.0 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
1.0 | 5.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.3 | 0.9 | GO:0034679 | integrin alpha9-beta1 complex(GO:0034679) |
0.3 | 1.0 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.2 | 3.1 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.2 | 0.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.2 | 0.5 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
0.2 | 0.5 | GO:1990423 | RZZ complex(GO:1990423) |
0.1 | 0.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.1 | 1.6 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.6 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.1 | 1.6 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.1 | 1.5 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.5 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.5 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.1 | 0.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 0.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.1 | 2.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.1 | 0.6 | GO:0030312 | external encapsulating structure(GO:0030312) |
0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.0 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 2.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 1.7 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.1 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.3 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.0 | 1.3 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 2.4 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 2.0 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 1.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.5 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.5 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.2 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.3 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.1 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.4 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.0 | 0.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 4.0 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.5 | 1.4 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
0.4 | 1.1 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.3 | 1.5 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.3 | 0.9 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.3 | 1.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.3 | 1.1 | GO:0004337 | geranyltranstransferase activity(GO:0004337) |
0.3 | 0.8 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.2 | 1.7 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.2 | 0.7 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.2 | 1.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.2 | 0.6 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
0.2 | 1.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.2 | 0.8 | GO:0042731 | PH domain binding(GO:0042731) |
0.2 | 1.3 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.2 | 0.6 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.2 | 1.3 | GO:0015288 | porin activity(GO:0015288) |
0.2 | 0.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.2 | 3.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.4 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
0.1 | 0.8 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.5 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 0.4 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) |
0.1 | 0.9 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
0.1 | 2.1 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 0.3 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.1 | 0.4 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 0.4 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 0.6 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.1 | GO:0036310 | annealing helicase activity(GO:0036310) annealing activity(GO:0097617) |
0.1 | 0.6 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 0.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 0.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.5 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.1 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.7 | GO:0034046 | poly(G) binding(GO:0034046) |
0.1 | 2.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 1.1 | GO:0001848 | complement binding(GO:0001848) |
0.1 | 0.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.1 | 1.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 0.2 | GO:0047598 | 7-dehydrocholesterol reductase activity(GO:0047598) |
0.1 | 0.2 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.1 | 0.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 0.4 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.1 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 0.2 | GO:0003844 | 1,4-alpha-glucan branching enzyme activity(GO:0003844) |
0.1 | 0.2 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.6 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 1.1 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.5 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
0.0 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) wide pore channel activity(GO:0022829) |
0.0 | 0.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 0.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.6 | GO:0008796 | bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796) |
0.0 | 0.2 | GO:0043515 | kinetochore binding(GO:0043515) |
0.0 | 0.9 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.2 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.0 | 0.2 | GO:0033691 | sialic acid binding(GO:0033691) |
0.0 | 1.9 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.5 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 1.1 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.0 | 0.5 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.0 | 1.2 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.3 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.1 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
0.0 | 0.6 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.0 | 0.3 | GO:0099604 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
0.0 | 0.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.4 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
0.0 | 0.6 | GO:0044653 | trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859) |
0.0 | 0.5 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.0 | 0.4 | GO:0015149 | hexose transmembrane transporter activity(GO:0015149) |
0.0 | 1.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 1.5 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.1 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.0 | 0.7 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.3 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.3 | GO:0016208 | AMP binding(GO:0016208) |
0.0 | 0.1 | GO:0030620 | U2 snRNA binding(GO:0030620) |
0.0 | 0.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 2.0 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.0 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.0 | 0.1 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.1 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.0 | 0.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 8.3 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 0.5 | GO:0003690 | double-stranded DNA binding(GO:0003690) |
0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.3 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.0 | 0.2 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
0.0 | 0.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.0 | 0.3 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) procollagen-proline dioxygenase activity(GO:0019798) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.0 | 0.2 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.0 | 0.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.7 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |