Motif ID: Cxxc1

Z-value: 0.410


Transcription factors associated with Cxxc1:

Gene SymbolEntrez IDGene Name
Cxxc1 ENSMUSG00000024560.6 Cxxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cxxc1mm10_v2_chr18_+_74216118_74216145-0.185.4e-01Click!


Activity profile for motif Cxxc1.

activity profile for motif Cxxc1


Sorted Z-values histogram for motif Cxxc1

Sorted Z-values for motif Cxxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cxxc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_89302545 0.972 ENSMUST00000061728.3
 Nog
noggin
chr3_+_68869563 0.871 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr8_-_122443404 0.560 ENSMUST00000006692.4
 Mvd
mevalonate (diphospho) decarboxylase
chrX_+_53607987 0.367 ENSMUST00000063384.3
ENSMUST00000169626.1
 Cxx1c

CAAX box 1C

chr17_-_14203695 0.352 ENSMUST00000053218.5
 Dact2
dapper homolog 2, antagonist of beta-catenin (xenopus)
chr3_-_8964037 0.342 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chrX_+_53607918 0.312 ENSMUST00000114827.1
 Cxx1c
CAAX box 1C
chr1_-_124045523 0.308 ENSMUST00000112606.1
 Dpp10
dipeptidylpeptidase 10
chr11_-_69921057 0.211 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr1_-_124045247 0.201 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr5_+_30588078 0.199 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr10_-_7681118 0.180 ENSMUST00000159977.1
ENSMUST00000162682.1
 Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr11_-_69920581 0.174 ENSMUST00000108610.1
 Eif5a
eukaryotic translation initiation factor 5A
chr5_+_143403819 0.164 ENSMUST00000110731.2
 Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chrX_-_7375830 0.155 ENSMUST00000115744.1
 Usp27x
ubiquitin specific peptidase 27, X chromosome
chr1_+_59256906 0.150 ENSMUST00000160662.1
ENSMUST00000114248.2
 Cdk15

cyclin-dependent kinase 15

chr15_+_82147238 0.137 ENSMUST00000023100.6
 Srebf2
sterol regulatory element binding factor 2
chr19_-_5273080 0.130 ENSMUST00000025786.7
 Pacs1
phosphofurin acidic cluster sorting protein 1
chr10_+_80249441 0.128 ENSMUST00000020361.6
 Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr11_+_71019593 0.121 ENSMUST00000133413.1
ENSMUST00000164220.1
ENSMUST00000048807.5
 Mis12


MIS12 homolog (yeast)


chr19_-_4439388 0.114 ENSMUST00000117462.1
ENSMUST00000048197.3
 Rhod

ras homolog gene family, member D

chr10_+_7681197 0.110 ENSMUST00000165952.1
 Lats1
large tumor suppressor
chr1_-_180813534 0.104 ENSMUST00000159789.1
ENSMUST00000081026.4
 H3f3a

H3 histone, family 3A

chr9_-_78108617 0.100 ENSMUST00000085311.6
 Fbxo9
f-box protein 9
chr3_-_101307079 0.097 ENSMUST00000097146.2
 Gm10355
predicted gene 10355
chr5_-_65391380 0.095 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
 Rpl9


ribosomal protein L9


chr5_-_65391408 0.093 ENSMUST00000057885.6
 Rpl9
ribosomal protein L9
chr12_-_54656496 0.092 ENSMUST00000056228.6
 Sptssa
serine palmitoyltransferase, small subunit A
chr10_+_50895651 0.088 ENSMUST00000020071.3
 Sim1
single-minded homolog 1 (Drosophila)
chr9_-_78108587 0.083 ENSMUST00000162625.1
ENSMUST00000159099.1
 Fbxo9

f-box protein 9

chr11_+_88068242 0.077 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr11_-_68386974 0.076 ENSMUST00000135141.1
 Ntn1
netrin 1
chr9_-_78109020 0.076 ENSMUST00000001402.7
 Fbxo9
f-box protein 9
chr2_+_112239468 0.075 ENSMUST00000028554.3
 Lpcat4
lysophosphatidylcholine acyltransferase 4
chr8_+_70594466 0.072 ENSMUST00000019283.9
 Isyna1
myo-inositol 1-phosphate synthase A1
chr8_-_111393810 0.071 ENSMUST00000038475.8
 Fa2h
fatty acid 2-hydroxylase
chr11_-_69920892 0.070 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
 Eif5a


eukaryotic translation initiation factor 5A


chr19_+_38931008 0.068 ENSMUST00000145051.1
 Hells
helicase, lymphoid specific
chr5_-_125389177 0.064 ENSMUST00000108707.2
 Ubc
ubiquitin C
chr5_+_125441546 0.063 ENSMUST00000049040.9
 Bri3bp
Bri3 binding protein
chr5_+_125389284 0.061 ENSMUST00000100700.2
 Gm10382
predicted gene 10382
chr18_-_43477764 0.057 ENSMUST00000057110.9
 Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chrX_-_106011766 0.054 ENSMUST00000139421.1
ENSMUST00000113566.2
 Magt1

magnesium transporter 1

chr10_+_128058947 0.052 ENSMUST00000052798.7
 Ptges3
prostaglandin E synthase 3 (cytosolic)
chr7_-_49636847 0.048 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr5_-_125389915 0.047 ENSMUST00000136312.1
 Ubc
ubiquitin C
chrX_+_48623737 0.044 ENSMUST00000114936.1
 Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_+_32205483 0.044 ENSMUST00000121182.1
 Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr17_+_86963279 0.037 ENSMUST00000139344.1
 Rhoq
ras homolog gene family, member Q
chr16_-_4420416 0.036 ENSMUST00000120080.1
 Adcy9
adenylate cyclase 9
chr19_-_36919606 0.029 ENSMUST00000057337.7
 Fgfbp3
fibroblast growth factor binding protein 3
chr10_+_128058974 0.019 ENSMUST00000084771.2
 Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_-_4758216 0.014 ENSMUST00000054294.4
 Fzd1
frizzled homolog 1 (Drosophila)
chr15_-_77153772 0.013 ENSMUST00000166610.1
ENSMUST00000111581.2
 Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr11_+_32205411 0.012 ENSMUST00000039601.3
ENSMUST00000149043.1
 Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr5_-_45857473 0.008 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
 Lcorl


ligand dependent nuclear receptor corepressor-like


chr8_+_92357787 0.006 ENSMUST00000034184.10
 Irx5
Iroquois related homeobox 5 (Drosophila)
chr5_-_35679416 0.003 ENSMUST00000114233.2
 Htra3
HtrA serine peptidase 3
chr7_+_45896941 0.001 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr11_-_77489666 0.001 ENSMUST00000037593.7
ENSMUST00000092892.3
 Ankrd13b

ankyrin repeat domain 13b

chr2_+_181680284 0.001 ENSMUST00000103042.3
 Tcea2
transcription elongation factor A (SII), 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.4 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.1 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.5 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.0 GO:0019955 cytokine binding(GO:0019955)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)