Motif ID: Ddit3

Z-value: 0.890


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_127290803-0.156.1e-01Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Showing 1 to 20 of 147 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 3.438 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr3_-_127409014 0.816 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
 Ank2


ankyrin 2, brain


chr3_-_127408986 0.774 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
 Ank2


ankyrin 2, brain


chr3_-_127409044 0.752 ENSMUST00000182704.1
 Ank2
ankyrin 2, brain
chr15_+_32244801 0.739 ENSMUST00000067458.6
 Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_-_109823585 0.692 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr3_-_127408937 0.684 ENSMUST00000183095.1
ENSMUST00000182610.1
 Ank2

ankyrin 2, brain

chr18_+_37421418 0.625 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chr17_-_15564322 0.621 ENSMUST00000147532.1
 Prdm9
PR domain containing 9
chr6_+_21215472 0.614 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr10_+_127195240 0.593 ENSMUST00000181578.1
 F420014N23Rik
RIKEN cDNA F420014N23 gene
chr17_-_35132050 0.571 ENSMUST00000025249.6
 Apom
apolipoprotein M
chr10_+_112271123 0.571 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr1_+_174501796 0.564 ENSMUST00000030039.7
 Fmn2
formin 2
chr17_-_46890405 0.560 ENSMUST00000086675.3
 A330017A19Rik
RIKEN cDNA A330017A19 gene
chr3_+_9403049 0.523 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
 C030034L19Rik


RIKEN cDNA C030034L19 gene


chr15_-_43869993 0.520 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr18_+_37333853 0.512 ENSMUST00000061717.2
 Pcdhb6
protocadherin beta 6
chr1_-_5019342 0.505 ENSMUST00000002533.8
 Rgs20
regulator of G-protein signaling 20
chr19_-_4334001 0.504 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.6 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.6 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.1 0.6 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.2 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.1 0.5 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0086080 connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)