Motif ID: Dlx1

Z-value: 1.000


Transcription factors associated with Dlx1:

Gene SymbolEntrez IDGene Name
Dlx1 ENSMUSG00000041911.3 Dlx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx1mm10_v2_chr2_+_71529085_715291100.771.4e-03Click!


Activity profile for motif Dlx1.

activity profile for motif Dlx1


Sorted Z-values histogram for motif Dlx1

Sorted Z-values for motif Dlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dlx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_11604828 3.632 ENSMUST00000025582.4
 Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr6_+_124304646 2.868 ENSMUST00000112541.2
ENSMUST00000032234.2
 Cd163

CD163 antigen

chr3_+_66219909 2.668 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chrM_+_7759 2.475 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_+_66386292 2.376 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr13_+_94083490 2.235 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr15_-_11037968 2.046 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr6_+_30541582 2.010 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr7_-_45103747 1.990 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr12_+_112760652 1.987 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr6_-_137169710 1.977 ENSMUST00000117919.1
 Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr12_+_77238093 1.850 ENSMUST00000177595.1
ENSMUST00000171770.2
 Fut8

fucosyltransferase 8

chrM_+_9452 1.819 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr8_+_94152607 1.775 ENSMUST00000034211.8
 Mt3
metallothionein 3
chr2_-_164171113 1.747 ENSMUST00000045196.3
 Kcns1
K+ voltage-gated channel, subfamily S, 1
chr5_-_70842617 1.649 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_+_125136692 1.642 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr9_-_123678782 1.620 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr2_+_116067213 1.585 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr19_-_32196393 1.559 ENSMUST00000151822.1
 Sgms1
sphingomyelin synthase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 130 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.9 GO:0006953 acute-phase response(GO:0006953)
0.5 2.8 GO:0036233 glycine import(GO:0036233)
0.9 2.7 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.6 2.6 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 2.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 2.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.2 GO:0051923 sulfation(GO:0051923)
0.1 2.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 2.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.1 2.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 2.0 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.2 1.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.6 1.8 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.4 1.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 1.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 1.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0070469 respiratory chain(GO:0070469)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.5 GO:0043205 fibril(GO:0043205)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 4.5 GO:0005525 GTP binding(GO:0005525)
0.4 3.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.9 GO:0042287 MHC protein binding(GO:0042287)
0.1 2.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.5 2.8 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.5 2.7 GO:0001849 complement component C1q binding(GO:0001849)
0.7 2.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 2.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 2.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 1.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 1.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)