Motif ID: Dmc1

Z-value: 1.985


Transcription factors associated with Dmc1:

Gene SymbolEntrez IDGene Name
Dmc1 ENSMUSG00000022429.10 Dmc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmc1mm10_v2_chr15_-_79605084_796051140.058.6e-01Click!


Activity profile for motif Dmc1.

activity profile for motif Dmc1


Sorted Z-values histogram for motif Dmc1

Sorted Z-values for motif Dmc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dmc1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_14229390 9.267 ENSMUST00000028045.2
 Mrc1
mannose receptor, C type 1
chr18_+_61105561 5.497 ENSMUST00000025523.6
 Csf1r
colony stimulating factor 1 receptor
chr10_-_105841323 4.348 ENSMUST00000046638.9
 Mettl25
methyltransferase like 25
chr16_-_43979050 4.175 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr8_+_66386292 4.140 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr7_-_45103747 3.635 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr5_+_112255813 3.549 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
 Crybb1


crystallin, beta B1


chr11_+_116532441 3.420 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
 Sphk1



sphingosine kinase 1



chr8_+_104340594 3.392 ENSMUST00000034343.4
 Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr3_+_95526777 3.342 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr13_-_92030897 3.318 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr10_-_117282262 3.263 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr1_+_95313607 3.186 ENSMUST00000059975.6
 Fam174a
family with sequence similarity 174, member A
chr18_-_82406777 3.134 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr14_+_75955003 3.075 ENSMUST00000050120.2
 Kctd4
potassium channel tetramerisation domain containing 4
chr15_+_34306666 2.874 ENSMUST00000163455.2
ENSMUST00000022947.5
 Matn2

matrilin 2

chr3_+_66219909 2.771 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr12_-_84876479 2.667 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
 Ltbp2


latent transforming growth factor beta binding protein 2


chr4_-_141598206 2.651 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1


chr9_+_21032038 2.615 ENSMUST00000019616.4
 Icam5
intercellular adhesion molecule 5, telencephalin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 9.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
1.7 6.9 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 4.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.3 4.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 4.2 GO:0018345 protein palmitoylation(GO:0018345)
0.2 4.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 3.8 GO:0010447 response to acidic pH(GO:0010447)
0.2 3.6 GO:0019835 cytolysis(GO:0019835)
0.0 3.5 GO:0007601 visual perception(GO:0007601)
0.6 3.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 3.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.3 3.3 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 3.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.0 3.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.5 2.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 2.9 GO:0048678 response to axon injury(GO:0048678)
0.9 2.8 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 2.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 2.5 GO:0001706 endoderm formation(GO:0001706)
0.5 2.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.7 GO:0010008 endosome membrane(GO:0010008)
2.3 6.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 4.5 GO:0005925 focal adhesion(GO:0005925)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.7 GO:0031012 extracellular matrix(GO:0031012)
0.7 3.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.3 2.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 2.5 GO:0097060 synaptic membrane(GO:0097060)
0.8 2.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 2.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.7 2.2 GO:0044299 C-fiber(GO:0044299)
0.2 2.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 2.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.0 GO:0008021 synaptic vesicle(GO:0008021)
0.4 1.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 10.2 GO:0005537 mannose binding(GO:0005537)
0.1 8.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 5.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.2 4.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 4.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.2 3.6 GO:0019770 IgG receptor activity(GO:0019770)
0.2 3.6 GO:0031005 filamin binding(GO:0031005)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 3.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 3.3 GO:0001968 fibronectin binding(GO:0001968)
1.0 3.1 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.9 GO:0070888 E-box binding(GO:0070888)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.6 2.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.6 2.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 2.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)