Motif ID: E2f3

Z-value: 0.948


Transcription factors associated with E2f3:

Gene SymbolEntrez IDGene Name
E2f3 ENSMUSG00000016477.11 E2f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f3mm10_v2_chr13_-_29984219_299843530.136.7e-01Click!


Activity profile for motif E2f3.

activity profile for motif E2f3


Sorted Z-values histogram for motif E2f3

Sorted Z-values for motif E2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_45857473 2.000 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr7_-_137314394 1.557 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr12_+_112146187 1.389 ENSMUST00000128402.2
Kif26a
kinesin family member 26A
chr19_+_40894692 1.184 ENSMUST00000050092.6
Zfp518a
zinc finger protein 518A
chr19_+_53600377 1.140 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr3_+_103576081 1.113 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6



synaptotagmin VI



chr9_-_79793507 1.013 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr9_-_79793378 0.949 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr19_+_41482632 0.947 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr3_-_41742471 0.910 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr3_+_33800158 0.864 ENSMUST00000139880.1
ENSMUST00000076916.6
ENSMUST00000142280.1
ENSMUST00000117915.1
ENSMUST00000108210.2
Ttc14




tetratricopeptide repeat domain 14




chr3_+_41742615 0.845 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chrX_-_105929206 0.780 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr4_+_32615473 0.765 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr3_+_33799791 0.721 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr3_+_69004969 0.720 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr19_-_9559204 0.677 ENSMUST00000090527.3
Stxbp3b
syntaxin-binding protein 3B
chrX_-_105929333 0.658 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr7_-_75309262 0.653 ENSMUST00000165175.1
Sv2b
synaptic vesicle glycoprotein 2 b
chr12_+_4917376 0.649 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.1 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 2.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.4 GO:0048484 enteric nervous system development(GO:0048484)
0.3 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 1.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 0.6 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 0.6 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.1 0.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.6 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.2 1.4 GO:0000796 condensin complex(GO:0000796)
0.2 1.1 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.2 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0030276 clathrin binding(GO:0030276)
0.3 2.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.3 1.1 GO:0036033 mediator complex binding(GO:0036033)
0.2 1.1 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.2 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 0.5 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.5 GO:0051010 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)