Motif ID: E2f4

Z-value: 1.094


Transcription factors associated with E2f4:

Gene SymbolEntrez IDGene Name
E2f4 ENSMUSG00000014859.8 E2f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f4mm10_v2_chr8_+_105297663_1052977420.156.0e-01Click!


Activity profile for motif E2f4.

activity profile for motif E2f4


Sorted Z-values histogram for motif E2f4

Sorted Z-values for motif E2f4



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_53638945 2.826 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr15_+_57912199 2.414 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chrY_-_90754821 2.364 ENSMUST00000177893.1
Gm21860
predicted gene, 21860
chrY_+_90784738 2.355 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr2_-_172940299 2.278 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr17_+_86753900 2.267 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr12_+_76533540 2.235 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_+_170009892 2.197 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr1_-_189688074 2.096 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr17_-_28350747 2.070 ENSMUST00000080572.7
ENSMUST00000156862.1
Tead3

TEA domain family member 3

chr19_+_6084983 2.030 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr11_-_101551837 1.951 ENSMUST00000017290.4
Brca1
breast cancer 1
chr15_-_76639840 1.799 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr7_+_126781483 1.793 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr17_-_28350600 1.784 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr2_+_125136692 1.711 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr9_-_82975475 1.689 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr17_-_25727364 1.665 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr13_+_23535411 1.547 ENSMUST00000080859.5
Hist1h3g
histone cluster 1, H3g
chr5_-_112228934 1.546 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr6_+_124830217 1.542 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr9_-_123678782 1.531 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr1_-_169531343 1.424 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_+_72438534 1.382 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr18_-_34751502 1.380 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr2_+_163054682 1.354 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr2_-_63184253 1.315 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr10_-_81427114 1.264 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
Nfic


nuclear factor I/C


chr4_+_134510999 1.187 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr1_-_169531447 1.181 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr2_-_26503814 1.150 ENSMUST00000028288.4
Notch1
notch 1
chr2_+_103970221 1.120 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr1_-_77515048 1.111 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr2_+_181319714 1.030 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr3_-_107969162 1.029 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr1_+_120340569 1.026 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr4_-_40722307 1.012 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr9_+_72438519 1.012 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr14_-_47418407 0.989 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr4_-_133967235 0.978 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chrX_+_36112110 0.960 ENSMUST00000033418.7
Il13ra1
interleukin 13 receptor, alpha 1
chr7_-_4789541 0.956 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr7_-_109865586 0.939 ENSMUST00000007423.5
ENSMUST00000106728.2
ENSMUST00000106729.1
Scube2


signal peptide, CUB domain, EGF-like 2


chr4_-_133967296 0.913 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr7_-_92874196 0.903 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr9_+_44134562 0.902 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chrX_-_164980310 0.890 ENSMUST00000004715.1
ENSMUST00000112248.2
Mospd2

motile sperm domain containing 2

chr4_-_133967893 0.890 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr4_+_84884418 0.882 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr17_+_25727726 0.880 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chr16_-_90727329 0.879 ENSMUST00000099554.4
Mis18a
MIS18 kinetochore protein homolog A (S. pombe)
chrX_-_164980279 0.856 ENSMUST00000112247.2
Mospd2
motile sperm domain containing 2
chr18_-_39490649 0.843 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr12_-_87147883 0.823 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr9_+_92250039 0.815 ENSMUST00000093801.3
Plscr1
phospholipid scramblase 1
chr10_-_88146867 0.799 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr9_-_83441065 0.792 ENSMUST00000034791.8
ENSMUST00000034793.8
Lca5

Leber congenital amaurosis 5 (human)

chr17_-_35046726 0.772 ENSMUST00000097338.4
Msh5
mutS homolog 5 (E. coli)
chrX_-_37110257 0.768 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr4_+_84884276 0.768 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr10_+_58255465 0.766 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr1_+_157412352 0.761 ENSMUST00000061537.5
2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr19_-_5366626 0.737 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chrX_+_8271133 0.732 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr5_-_112228900 0.696 ENSMUST00000182509.1
Miat
myocardial infarction associated transcript (non-protein coding)
chr4_-_43562397 0.694 ENSMUST00000030187.7
Tln1
talin 1
chr1_-_191397026 0.683 ENSMUST00000067976.3
Ppp2r5a
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
chr4_+_11558914 0.636 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr6_-_56704673 0.636 ENSMUST00000170382.2
Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_142881942 0.631 ENSMUST00000043812.8
Pkn2
protein kinase N2
chr2_+_181319806 0.619 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr5_-_34187670 0.605 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr4_-_133967953 0.597 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr14_-_33978751 0.583 ENSMUST00000166737.1
Zfp488
zinc finger protein 488
chr10_+_17723220 0.579 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr5_-_138172383 0.521 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr12_+_117843873 0.518 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr17_-_84187939 0.510 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chrX_+_105079761 0.510 ENSMUST00000119477.1
Pbdc1
polysaccharide biosynthesis domain containing 1
chr13_-_23745511 0.506 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr19_-_6084941 0.499 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr7_-_38107490 0.498 ENSMUST00000108023.3
Ccne1
cyclin E1
chrX_-_8074720 0.496 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr1_+_52630692 0.495 ENSMUST00000165859.1
Tmem194b
transmembrane protein 194B
chr17_+_88440711 0.493 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr17_-_29237759 0.487 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr9_+_100643605 0.475 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr18_+_65800543 0.470 ENSMUST00000025394.6
ENSMUST00000153193.1
Sec11c

SEC11 homolog C (S. cerevisiae)

chr12_-_4233958 0.453 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr11_+_78037959 0.434 ENSMUST00000073660.6
Flot2
flotillin 2
chr17_+_56673225 0.415 ENSMUST00000002445.8
Ranbp3
RAN binding protein 3
chr17_-_12507704 0.412 ENSMUST00000024595.2
Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr17_+_50698525 0.409 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr9_+_118926453 0.391 ENSMUST00000073109.5
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr9_+_119937606 0.383 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chr11_+_78037931 0.382 ENSMUST00000072289.5
ENSMUST00000100784.2
Flot2

flotillin 2

chr7_+_24884611 0.368 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr7_+_97579868 0.364 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr2_+_145934800 0.359 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
4930529M08Rik




RIKEN cDNA 4930529M08 gene




chr12_+_106010263 0.358 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
Vrk1


vaccinia related kinase 1


chr19_-_6084679 0.356 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr7_+_24884651 0.355 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr18_+_34751803 0.332 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr19_+_8735808 0.326 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr17_+_34982099 0.319 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_108834601 0.310 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr5_-_138171813 0.308 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr9_+_107950952 0.305 ENSMUST00000049348.3
Traip
TRAF-interacting protein
chr17_+_34982154 0.298 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_76488436 0.290 ENSMUST00000101618.2
Tsc22d1
TSC22 domain family, member 1
chr17_+_34981847 0.282 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_136624901 0.280 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chrX_+_38600626 0.270 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr2_+_3513035 0.266 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chr9_-_44134481 0.261 ENSMUST00000180670.1
Gm10687
predicted gene 10687
chr7_-_127422002 0.261 ENSMUST00000106300.1
Zfp688
zinc finger protein 688
chr17_-_87025353 0.257 ENSMUST00000024957.6
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
chr8_-_11550689 0.244 ENSMUST00000049461.5
Cars2
cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
chr4_+_43562672 0.225 ENSMUST00000167751.1
ENSMUST00000132631.1
Creb3

cAMP responsive element binding protein 3

chr9_+_100643448 0.219 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr15_-_98831498 0.212 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr4_+_95967205 0.207 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr6_+_113531675 0.196 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr2_-_62646146 0.195 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr14_-_65953728 0.184 ENSMUST00000042046.3
Scara3
scavenger receptor class A, member 3
chr19_-_6084873 0.181 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr7_+_6383310 0.175 ENSMUST00000081022.7
Zfp28
zinc finger protein 28
chr4_-_116123618 0.173 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chr2_+_112284561 0.171 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr11_+_98907801 0.168 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr14_+_31019125 0.166 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chrX_+_164980592 0.165 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fancb


Fanconi anemia, complementation group B


chr5_+_9100681 0.161 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr4_-_58553553 0.148 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr2_+_129593195 0.143 ENSMUST00000099113.3
ENSMUST00000103202.3
Sirpa

signal-regulatory protein alpha

chr12_+_99884498 0.140 ENSMUST00000153627.1
Tdp1
tyrosyl-DNA phosphodiesterase 1
chr5_-_24447587 0.136 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr17_-_66101466 0.117 ENSMUST00000024909.8
ENSMUST00000147484.1
ENSMUST00000143987.1
Ndufv2


NADH dehydrogenase (ubiquinone) flavoprotein 2


chr14_+_55578123 0.108 ENSMUST00000174484.1
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_63184170 0.107 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr11_+_16951371 0.106 ENSMUST00000109635.1
ENSMUST00000061327.1
Fbxo48

F-box protein 48

chr5_-_33652296 0.100 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr5_+_113772748 0.099 ENSMUST00000026937.5
ENSMUST00000112311.1
ENSMUST00000112312.1
Iscu


IscU iron-sulfur cluster scaffold homolog (E. coli)


chr14_-_87141114 0.098 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chrX_-_78583882 0.071 ENSMUST00000114025.1
ENSMUST00000134602.1
ENSMUST00000114024.2
Prrg1


proline rich Gla (G-carboxyglutamic acid) 1


chr1_+_9798123 0.071 ENSMUST00000168907.1
ENSMUST00000166384.1
Sgk3

serum/glucocorticoid regulated kinase 3

chr12_+_4234023 0.047 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr19_+_46003468 0.040 ENSMUST00000099393.2
Hps6
Hermansky-Pudlak syndrome 6
chr5_+_33721724 0.033 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
Fgfr3



fibroblast growth factor receptor 3



chr2_+_153649617 0.026 ENSMUST00000109771.1
Dnmt3b
DNA methyltransferase 3B
chr7_-_16285454 0.026 ENSMUST00000174270.1
Ccdc9
coiled-coil domain containing 9
chr5_+_138171997 0.004 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chrX_+_12587791 0.002 ENSMUST00000033313.2
Atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
chrX_+_105079735 0.000 ENSMUST00000033577.4
Pbdc1
polysaccharide biosynthesis domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.7 2.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.7 2.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 2.3 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.5 1.4 GO:0000087 mitotic M phase(GO:0000087)
0.4 1.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.4 1.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.4 1.1 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.4 1.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 3.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.3 1.0 GO:0019043 establishment of viral latency(GO:0019043)
0.3 0.8 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.3 0.8 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 1.5 GO:0036233 glycine import(GO:0036233)
0.2 2.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 3.0 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.8 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.2 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.7 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.2 0.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 3.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.7 GO:0015816 glycine transport(GO:0015816)
0.1 0.4 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 1.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.8 GO:0031297 replication fork processing(GO:0031297)
0.1 2.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.1 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.7 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.8 GO:0006284 base-excision repair(GO:0006284)
0.1 0.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.1 2.9 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 2.1 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.4 GO:0051608 organic cation transport(GO:0015695) quaternary ammonium group transport(GO:0015697) histamine transport(GO:0051608)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 1.4 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.5 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0031262 Ndc80 complex(GO:0031262)
0.3 1.4 GO:0031523 Myb complex(GO:0031523)
0.3 1.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 1.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 2.0 GO:0008278 cohesin complex(GO:0008278)
0.2 1.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.8 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.2 2.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 2.6 GO:0042555 MCM complex(GO:0042555)
0.2 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.2 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0000922 spindle pole(GO:0000922)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0000405 bubble DNA binding(GO:0000405)
0.3 1.1 GO:0042731 PH domain binding(GO:0042731)
0.3 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 2.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 2.3 GO:0050897 cobalt ion binding(GO:0050897)
0.2 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.4 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 2.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)